LAMA2 (laminin subunit alpha 2) - Rat Genome Database

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Gene: LAMA2 (laminin subunit alpha 2) Sus scrofa
Analyze
Symbol: LAMA2
Name: laminin subunit alpha 2
RGD ID: 14240609
Description: ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN axon guidance (ortholog); positive regulation of synaptic transmission, cholinergic (ortholog); Schwann cell differentiation (ortholog); ASSOCIATED WITH Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 23 (ortholog); Charcot-Marie-Tooth disease (ortholog); congenital merosin-deficient muscular dystrophy 1A (ortholog); FOUND IN basement membrane (ortholog); dendritic spine (ortholog); neuromuscular junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: laminin, alpha 2; LOW QUALITY PROTEIN: laminin subunit alpha-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl133,867,639 - 34,359,698 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1133,765,412 - 34,359,741 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2137,284,919 - 37,545,503 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463  


Genomics

Comparative Map Data
LAMA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl133,867,639 - 34,359,698 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1133,765,412 - 34,359,741 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2137,284,919 - 37,545,503 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LAMA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6128,883,138 - 129,516,566 (+)EnsemblGRCh38hg38GRCh38
GRCh386128,883,138 - 129,516,566 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376129,204,283 - 129,837,711 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366129,245,979 - 129,879,404 (+)NCBINCBI36hg18NCBI36
Build 346129,246,034 - 129,879,401NCBI
Celera6129,950,556 - 130,583,793 (+)NCBI
Cytogenetic Map6q22.33NCBI
HuRef6126,785,527 - 127,418,362 (+)NCBIHuRef
CHM1_16129,468,357 - 130,101,369 (+)NCBICHM1_1
Lama2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391026,857,281 - 27,493,021 (-)NCBIGRCm39mm39
GRCm39 Ensembl1026,856,032 - 27,495,754 (-)Ensembl
GRCm381026,981,285 - 27,617,191 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1026,980,036 - 27,619,758 (-)EnsemblGRCm38mm10GRCm38
MGSCv371026,701,091 - 27,336,748 (-)NCBIGRCm37mm9NCBIm37
MGSCv361026,670,819 - 27,306,267 (-)NCBImm8
Celera1027,907,208 - 28,541,586 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1014.23NCBI
Lama2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2117,672,675 - 18,320,641 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl117,672,536 - 18,320,530 (+)Ensembl
Rnor_6.0118,491,264 - 19,143,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl118,491,384 - 19,143,269 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0120,002,787 - 20,647,256 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4118,203,466 - 18,885,462 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1118,324,930 - 18,885,310 (+)NCBI
Celera116,078,601 - 16,724,118 (+)NCBICelera
Cytogenetic Map1p12NCBI
Lama2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554369,830,030 - 10,399,891 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554369,829,777 - 10,400,101 (+)NCBIChiLan1.0ChiLan1.0
LAMA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16130,781,676 - 131,415,549 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6130,781,781 - 131,415,337 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06126,672,013 - 127,307,870 (+)NCBIMhudiblu_PPA_v0panPan3
LAMA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1167,645,461 - 68,096,506 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl167,611,122 - 68,095,914 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha168,254,521 - 68,844,637 (+)NCBI
ROS_Cfam_1.0167,721,690 - 68,305,337 (+)NCBI
UMICH_Zoey_3.1167,644,723 - 68,228,165 (+)NCBI
UNSW_CanFamBas_1.0167,427,961 - 68,011,313 (+)NCBI
UU_Cfam_GSD_1.0168,070,825 - 68,654,877 (+)NCBI
Lama2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946117,593,991 - 118,159,491 (+)NCBI
SpeTri2.0NW_004936639259,662 - 825,170 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11344,074,128 - 44,688,187 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1344,073,525 - 44,531,889 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604016,239,880 - 16,874,460 (-)NCBIVero_WHO_p1.0
Lama2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247533,194,678 - 3,794,145 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 3 1 3 2 2 2 1
Low 8 1 2 2 21 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000036716   ⟹   ENSSSCP00000045834
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl133,867,639 - 34,359,698 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000039085   ⟹   ENSSSCP00000037113
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl133,867,639 - 34,359,698 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000059566   ⟹   ENSSSCP00000038855
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl133,867,639 - 34,359,698 (-)Ensembl
RefSeq Acc Id: XM_021084463   ⟹   XP_020940122
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1133,765,412 - 34,359,741 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020940122 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020940122   ⟸   XM_021084463
- Sequence:
RefSeq Acc Id: ENSSSCP00000037113   ⟸   ENSSSCT00000039085
RefSeq Acc Id: ENSSSCP00000038855   ⟸   ENSSSCT00000059566
RefSeq Acc Id: ENSSSCP00000045834   ⟸   ENSSSCT00000036716

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000033894 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000037113 UniProtKB/TrEMBL
  ENSSSCP00000038855 UniProtKB/TrEMBL
  ENSSSCP00000045834 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000036716 UniProtKB/TrEMBL
  ENSSSCT00000039085 UniProtKB/TrEMBL
  ENSSSCT00000059566 UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Laminin_aI UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_IV UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
NCBI Gene LAMA2 ENTREZGENE
Pfam Laminin_B UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_I UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
PROSITE EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  LAMININ_IVA UniProtKB/TrEMBL
  LAMININ_NTER UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  LamB UniProtKB/TrEMBL
  LamNT UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/TrEMBL
UniProt A0A287A027_PIG UniProtKB/TrEMBL
  A0A287A502_PIG UniProtKB/TrEMBL
  A0A287AP44_PIG UniProtKB/TrEMBL
VGNC ID VGNC:101493 ENTREZGENE