UPP2 (uridine phosphorylase 2) - Rat Genome Database
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Gene: UPP2 (uridine phosphorylase 2) Sus scrofa
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Symbol: UPP2
Name: uridine phosphorylase 2
RGD ID: 14238873
Description: ENCODES a protein that exhibits uridine phosphorylase activity (ortholog); INVOLVED IN CMP catabolic process (ortholog); UMP catabolic process (ortholog); uridine catabolic process (ortholog); PARTICIPATES IN beta-ureidopropionase deficiency pathway; dihydropyrimidinase deficiency pathway; mitochondrial neurogastrointestinal encephalopathy syndrome pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1565,088,284 - 65,131,789 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11565,088,652 - 65,131,739 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21572,235,731 - 72,280,652 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
UPP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1565,088,284 - 65,131,789 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11565,088,652 - 65,131,739 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21572,235,731 - 72,280,652 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UPP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2157,876,702 - 158,136,154 (+)EnsemblGRCh38hg38GRCh38
GRCh382157,995,179 - 158,136,154 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372158,733,213 - 158,992,666 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh372158,851,691 - 158,992,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362158,559,937 - 158,700,724 (+)NCBINCBI36hg18NCBI36
Build 342158,677,198 - 158,817,985NCBI
Celera2152,468,457 - 152,609,424 (+)NCBI
Cytogenetic Map2q24.1NCBI
HuRef2150,739,887 - 150,880,962 (+)NCBIHuRef
CHM1_12158,857,583 - 158,998,565 (+)NCBICHM1_1
Upp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39258,456,329 - 58,685,858 (+)NCBIGRCm39mm39
GRCm38258,566,317 - 58,795,846 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl258,567,298 - 58,792,971 (+)EnsemblGRCm38mm10GRCm38
MGSCv37258,607,596 - 58,643,079 (+)NCBIGRCm37mm9NCBIm37
MGSCv36258,570,571 - 58,606,054 (+)NCBImm8
Celera260,510,835 - 60,545,982 (+)NCBICelera
Cytogenetic Map2C1.1NCBI
Upp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2343,273,048 - 43,317,417 (+)NCBI
Rnor_6.0 Ensembl344,806,106 - 44,846,464 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0344,806,106 - 44,846,464 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0349,922,719 - 49,961,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4340,492,002 - 40,536,956 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1340,380,721 - 40,432,184 (+)NCBI
Celera341,338,432 - 41,381,638 (+)NCBICelera
Cytogenetic Map3q21NCBI
Upp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544915,365,106 - 15,405,235 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544915,355,592 - 15,405,997 (-)NCBIChiLan1.0ChiLan1.0
UPP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B162,603,164 - 162,636,231 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B162,496,507 - 162,636,231 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B45,363,103 - 45,400,281 (+)NCBIMhudiblu_PPA_v0panPan3
Upp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493646920,465,767 - 20,513,084 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UPP2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11043,510,752 - 43,545,133 (+)NCBI
Upp2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247327,574,609 - 7,641,345 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system nervous system renal system reproductive system
High
Medium 1 2
Low 1 3 22
Below cutoff 6 1 1 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000028912   ⟹   ENSSSCP00000026634
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1565,088,284 - 65,131,789 (+)Ensembl
RefSeq Acc Id: XM_021076462   ⟹   XP_020932121
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11565,088,653 - 65,131,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021076463   ⟹   XP_020932122
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11565,088,652 - 65,131,739 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020932121 (Get FASTA)   NCBI Sequence Viewer  
  XP_020932122 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020932122   ⟸   XM_021076463
- Sequence:
RefSeq Acc Id: XP_020932121   ⟸   XM_021076462
- Sequence:
RefSeq Acc Id: ENSSSCP00000026634   ⟸   ENSSSCT00000028912
Protein Domains
PNP_UDP_1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000021938 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070025893 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000026634 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070043810 UniProtKB/TrEMBL
  ENSSSCP00070043811 UniProtKB/TrEMBL
  ENSSSCP00070043812 UniProtKB/TrEMBL
  ENSSSCP00070043814 UniProtKB/TrEMBL
  ENSSSCP00070043816 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000028912 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070051786 UniProtKB/TrEMBL
  ENSSSCT00070051787 UniProtKB/TrEMBL
  ENSSSCT00070051789 UniProtKB/TrEMBL
  ENSSSCT00070051791 UniProtKB/TrEMBL
  ENSSSCT00070051792 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1580 UniProtKB/TrEMBL
InterPro Nucleoside_phosphorylase_CS UniProtKB/TrEMBL
  Nucleoside_phosphorylase_d UniProtKB/TrEMBL
  Nucleoside_phosphorylase_sf UniProtKB/TrEMBL
  Uridine_phosphorylase_euk UniProtKB/TrEMBL
NCBI Gene UPP2 ENTREZGENE
Pfam PNP_UDP_1 UniProtKB/TrEMBL
PROSITE PNP_UDP_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF53167 UniProtKB/TrEMBL
TIGRFAMs euk_UDPppase UniProtKB/TrEMBL
UniProt A0A4X1VPR2_PIG UniProtKB/TrEMBL
  A0A4X1VQJ2_PIG UniProtKB/TrEMBL
  A0A4X1VRQ8_PIG UniProtKB/TrEMBL
  I3LRA0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95986 ENTREZGENE