EMP2 (epithelial membrane protein 2) - Rat Genome Database

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Gene: EMP2 (epithelial membrane protein 2) Sus scrofa
Analyze
Symbol: EMP2
Name: epithelial membrane protein 2
RGD ID: 14236182
Description: ENCODES a protein that exhibits integrin binding (inferred); kinase binding (inferred); protein kinase binding (inferred); INVOLVED IN caveola assembly (ortholog); cell population proliferation (ortholog); positive regulation of cell-matrix adhesion (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 1C (ortholog); genetic disease (ortholog); Landau-Kleffner syndrome (ortholog); FOUND IN caveola (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl332,450,604 - 32,492,721 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1332,449,496 - 32,493,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2333,257,119 - 33,291,408 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
EMP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl332,450,604 - 32,492,721 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1332,449,496 - 32,493,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2333,257,119 - 33,291,408 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EMP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381610,528,422 - 10,580,598 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1610,528,422 - 10,580,632 (-)EnsemblGRCh38hg38GRCh38
GRCh371610,622,279 - 10,674,455 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361610,533,476 - 10,582,040 (-)NCBINCBI36Build 36hg18NCBI36
Build 341610,533,475 - 10,582,040NCBI
Celera1610,790,221 - 10,843,547 (-)NCBICelera
Cytogenetic Map16p13.13NCBI
HuRef1610,541,152 - 10,593,355 (-)NCBIHuRef
CHM1_11610,622,208 - 10,674,485 (-)NCBICHM1_1
T2T-CHM13v2.01610,564,353 - 10,616,512 (-)NCBIT2T-CHM13v2.0
Emp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391610,099,613 - 10,131,832 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1610,099,613 - 10,131,832 (-)EnsemblGRCm39 Ensembl
GRCm381610,281,749 - 10,313,968 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1610,281,749 - 10,313,968 (-)EnsemblGRCm38mm10GRCm38
MGSCv371610,281,842 - 10,314,061 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361610,195,337 - 10,227,546 (-)NCBIMGSCv36mm8
Celera1610,915,145 - 10,947,388 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map165.54NCBI
Emp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8105,866,869 - 5,901,533 (+)NCBIGRCr8
mRatBN7.2105,360,073 - 5,394,734 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl105,360,073 - 5,394,733 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1010,056,350 - 10,090,896 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0109,577,512 - 9,612,176 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0105,215,785 - 5,250,323 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0105,433,248 - 5,467,840 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl105,433,248 - 5,467,839 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0104,254,720 - 4,288,863 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4105,311,157 - 5,348,038 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1105,311,156 - 5,348,037 (+)NCBI
Celera104,376,437 - 4,410,636 (+)NCBICelera
Cytogenetic Map10q11NCBI
Emp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554427,826,738 - 7,860,028 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554427,826,967 - 7,862,035 (+)NCBIChiLan1.0ChiLan1.0
EMP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21811,072,654 - 11,124,792 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11614,848,582 - 14,900,614 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0169,465,589 - 9,517,593 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11610,694,425 - 10,744,744 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1610,694,425 - 10,744,744 (-)Ensemblpanpan1.1panPan2
EMP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1632,026,908 - 32,060,447 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl632,026,916 - 32,057,693 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha633,409,027 - 33,443,115 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0632,209,301 - 32,239,471 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1632,023,125 - 32,057,265 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0631,897,121 - 31,930,062 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0632,321,409 - 32,355,603 (+)NCBIUU_Cfam_GSD_1.0
Emp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344111,008,817 - 111,016,703 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365308,854,203 - 8,862,126 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365308,854,266 - 8,862,127 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EMP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1510,013,722 - 10,060,880 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl510,014,121 - 10,028,949 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606820,100,209 - 20,153,152 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Emp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248247,879,425 - 7,915,472 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248247,881,258 - 7,915,010 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EMP2
1217 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 5 1 2 3 1
Low 5 4 3 4 23 2
Below cutoff 2

Sequence


RefSeq Acc Id: ENSSSCT00000064420   ⟹   ENSSSCP00000037610
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl332,450,604 - 32,492,721 (+)Ensembl
RefSeq Acc Id: XM_021086638   ⟹   XP_020942297
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1332,449,497 - 32,473,903 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021086639   ⟹   XP_020942298
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1332,449,496 - 32,460,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021086640   ⟹   XP_020942299
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1332,450,504 - 32,493,245 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021086641   ⟹   XP_020942300
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1332,450,510 - 32,493,245 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021086642   ⟹   XP_020942301
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1332,450,502 - 32,493,245 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020942298   ⟸   XM_021086639
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020942297   ⟸   XM_021086638
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020942301   ⟸   XM_021086642
- Peptide Label: isoform X3
- UniProtKB: A0A287A649 (UniProtKB/TrEMBL),   A0A4X1VS33 (UniProtKB/TrEMBL),   A0A8D0JFI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020942299   ⟸   XM_021086640
- Peptide Label: isoform X3
- UniProtKB: A0A287A649 (UniProtKB/TrEMBL),   A0A4X1VS33 (UniProtKB/TrEMBL),   A0A8D0JFI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020942300   ⟸   XM_021086641
- Peptide Label: isoform X3
- UniProtKB: A0A287A649 (UniProtKB/TrEMBL),   A0A4X1VS33 (UniProtKB/TrEMBL),   A0A8D0JFI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000037610   ⟸   ENSSSCT00000064420


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037065 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005023532 UniProtKB/TrEMBL
  ENSSSCG00025051220 UniProtKB/TrEMBL
  ENSSSCG00035066956 UniProtKB/TrEMBL
  ENSSSCG00045000984 UniProtKB/TrEMBL
  ENSSSCG00065076673 UniProtKB/TrEMBL
  ENSSSCG00070025957 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000064420 ENTREZGENE
  ENSSSCT00000064420.3 UniProtKB/TrEMBL
  ENSSSCT00005037219.1 UniProtKB/TrEMBL
  ENSSSCT00025069982.1 UniProtKB/TrEMBL
  ENSSSCT00035090280.1 UniProtKB/TrEMBL
  ENSSSCT00045001452.1 UniProtKB/TrEMBL
  ENSSSCT00065105913.1 UniProtKB/TrEMBL
  ENSSSCT00070051941.1 UniProtKB/TrEMBL
  ENSSSCT00070051942.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro EMP-2 UniProtKB/TrEMBL
  PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
  PMP22_EMP_MP20 UniProtKB/TrEMBL
NCBI Gene EMP2 ENTREZGENE
PANTHER EPITHELIAL MEMBRANE PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR10671:SF32 UniProtKB/TrEMBL
Pfam PMP22_Claudin UniProtKB/TrEMBL
PRINTS EPMEMFAMILY UniProtKB/TrEMBL
  EPMEMPROT2 UniProtKB/TrEMBL
PROSITE PMP22_1 UniProtKB/TrEMBL
  PMP22_2 UniProtKB/TrEMBL
UniProt A0A287A649 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VS33 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JFI0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:87689 ENTREZGENE