PPTC7 (protein phosphatase targeting COQ7) - Rat Genome Database

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Gene: PPTC7 (protein phosphatase targeting COQ7) Sus scrofa
Analyze
Symbol: PPTC7
Name: protein phosphatase targeting COQ7
RGD ID: 14229849
Description: ENCODES a protein that exhibits metal ion binding (inferred); myosin phosphatase activity (inferred); phosphoprotein phosphatase activity (inferred); INVOLVED IN regulation of ubiquinone biosynthetic process (inferred); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein phosphatase PTC7 homolog; PTC7 protein phosphatase homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1431,906,262 - 31,946,554 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11431,905,379 - 31,946,555 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21433,827,421 - 33,868,659 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
PPTC7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1431,906,262 - 31,946,554 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11431,905,379 - 31,946,555 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21433,827,421 - 33,868,659 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPTC7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812110,533,245 - 110,583,318 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12110,533,245 - 110,583,318 (-)EnsemblGRCh38hg38GRCh38
GRCh3712110,971,050 - 111,021,123 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612109,456,620 - 109,505,447 (-)NCBINCBI36Build 36hg18NCBI36
Celera12110,598,937 - 110,647,770 (-)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12107,990,424 - 108,038,697 (-)NCBIHuRef
CHM1_112110,939,903 - 110,988,724 (-)NCBICHM1_1
T2T-CHM13v2.012110,510,939 - 110,561,010 (-)NCBIT2T-CHM13v2.0
Pptc7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395122,422,461 - 122,462,344 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5122,422,428 - 122,462,344 (+)EnsemblGRCm39 Ensembl
GRCm385122,284,398 - 122,324,281 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5122,284,365 - 122,324,281 (+)EnsemblGRCm38mm10GRCm38
MGSCv375122,734,407 - 122,774,290 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365122,545,015 - 122,584,898 (+)NCBIMGSCv36mm8
Celera5119,366,872 - 119,406,757 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.28NCBI
Pptc7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,910,728 - 39,949,101 (-)NCBIGRCr8
mRatBN7.21234,249,963 - 34,288,339 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1234,249,977 - 34,288,339 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,422,353 - 35,460,753 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01236,033,599 - 36,071,984 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,086,069 - 35,124,449 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,731,107 - 39,769,480 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,731,121 - 39,769,480 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,612,134 - 41,650,388 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41235,445,302 - 35,483,671 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11235,311,411 - 35,347,052 (-)NCBI
Celera1235,920,779 - 35,959,227 (-)NCBICelera
Cytogenetic Map12q16NCBI
Pptc7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554827,445,218 - 7,484,952 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554827,445,218 - 7,484,939 (-)NCBIChiLan1.0ChiLan1.0
PPTC7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210118,594,143 - 118,644,387 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112118,590,546 - 118,639,422 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012108,103,217 - 108,152,088 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112111,499,419 - 111,547,288 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12111,499,419 - 111,548,285 (-)Ensemblpanpan1.1panPan2
PPTC7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,345,690 - 8,383,902 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,349,453 - 8,383,617 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha268,509,240 - 8,547,247 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0268,606,290 - 8,642,035 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,603,767 - 8,642,254 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1268,562,698 - 8,600,724 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0268,621,651 - 8,659,686 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0268,577,006 - 8,615,042 (-)NCBIUU_Cfam_GSD_1.0
Pptc7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118155,947,536 - 155,988,201 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365583,490,808 - 3,532,345 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365583,491,225 - 3,531,886 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPTC7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111105,774,912 - 105,823,882 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11105,778,596 - 105,823,836 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037139,293,778 - 139,344,004 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pptc7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474721,320,617 - 21,358,904 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474721,320,525 - 21,358,830 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PPTC7
547 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 1 5 2 17 2 1 3
Low 2 6 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000010768   ⟹   ENSSSCP00000010488
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1431,906,262 - 31,946,554 (-)Ensembl
RefSeq Acc Id: XM_003132884   ⟹   XP_003132932
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11431,905,379 - 31,946,555 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003132932   ⟸   XM_003132884
- UniProtKB: A0A4X1U4H3 (UniProtKB/TrEMBL),   F1RNM7 (UniProtKB/TrEMBL),   A0A8D0IQS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010488   ⟸   ENSSSCT00000010768
Protein Domains
PPM-type phosphatase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009825 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005017771 UniProtKB/TrEMBL
  ENSSSCG00015054029 UniProtKB/TrEMBL
  ENSSSCG00025035086 UniProtKB/TrEMBL
  ENSSSCG00030060876 UniProtKB/TrEMBL
  ENSSSCG00035067658 UniProtKB/TrEMBL
  ENSSSCG00040004705 UniProtKB/TrEMBL
  ENSSSCG00045020623 UniProtKB/TrEMBL
  ENSSSCG00050001318 UniProtKB/TrEMBL
  ENSSSCG00055019882 UniProtKB/TrEMBL
  ENSSSCG00060030834 UniProtKB/TrEMBL
  ENSSSCG00065077092 UniProtKB/TrEMBL
  ENSSSCG00070013969 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000010768 ENTREZGENE
  ENSSSCT00000010768.5 UniProtKB/TrEMBL
  ENSSSCT00005028093.1 UniProtKB/TrEMBL
  ENSSSCT00015071954.1 UniProtKB/TrEMBL
  ENSSSCT00025047855.1 UniProtKB/TrEMBL
  ENSSSCT00030085051.1 UniProtKB/TrEMBL
  ENSSSCT00035091268.1 UniProtKB/TrEMBL
  ENSSSCT00040006269.1 UniProtKB/TrEMBL
  ENSSSCT00045035193.1 UniProtKB/TrEMBL
  ENSSSCT00050001573.1 UniProtKB/TrEMBL
  ENSSSCT00055038972.1 UniProtKB/TrEMBL
  ENSSSCT00060041667.1 UniProtKB/TrEMBL
  ENSSSCT00065106584.1 UniProtKB/TrEMBL
  ENSSSCT00070027337.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.40.10 UniProtKB/TrEMBL
InterPro PPM-type_dom_sf UniProtKB/TrEMBL
  PPM-type_phosphatase_dom UniProtKB/TrEMBL
  PPTC7 UniProtKB/TrEMBL
NCBI Gene PPTC7 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE PTC7 HOMOLOG UniProtKB/TrEMBL
  PTHR12320 UniProtKB/TrEMBL
Pfam SpoIIE UniProtKB/TrEMBL
PROSITE PPM_2 UniProtKB/TrEMBL
SMART PP2C_SIG UniProtKB/TrEMBL
  PP2Cc UniProtKB/TrEMBL
Superfamily-SCOP SSF81606 UniProtKB/TrEMBL
UniProt A0A4X1U4H3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IQS4 ENTREZGENE, UniProtKB/TrEMBL
  F1RNM7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91765 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-25 PPTC7  protein phosphatase targeting COQ7  PPTC7  PTC7 protein phosphatase homolog  Symbol and/or name change 5135510 APPROVED