SI (sucrase-isomaltase) - Rat Genome Database

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Gene: SI (sucrase-isomaltase) Sus scrofa
Analyze
Symbol: SI
Name: sucrase-isomaltase
RGD ID: 14227603
Description: ENCODES a protein that exhibits beta-fructofuranosidase activity (ortholog); oligo-1,6-glucosidase activity (ortholog); INVOLVED IN aging (ortholog); response to fructose (ortholog); response to glucocorticoid (ortholog); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; glycogen storage disease type III pathway; glycogen storage disease type IV pathway; ASSOCIATED WITH colitis (ortholog); congenital sucrase-isomaltase deficiency (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN brush border (ortholog); membrane raft (ortholog); INTERACTS WITH bisphenol A; choline; cyanocob(III)alamin
Type: protein-coding
RefSeq Status: MODEL
Also known as: Sucrase-isomaltase, intestinal
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13104,296,283 - 104,379,478 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113104,296,281 - 104,379,558 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213112,716,702 - 112,812,308 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

Genomics

Comparative Map Data
SI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13104,296,283 - 104,379,478 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113104,296,281 - 104,379,558 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213112,716,702 - 112,812,308 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3164,978,898 - 165,078,496 (-)EnsemblGRCh38hg38GRCh38
GRCh383164,978,898 - 165,078,496 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373164,696,686 - 164,796,284 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363166,179,380 - 166,278,976 (-)NCBINCBI36hg18NCBI36
Build 343166,179,388 - 166,278,984NCBI
Celera3163,095,850 - 163,195,264 (-)NCBI
Cytogenetic Map3q26.1NCBI
HuRef3162,066,552 - 162,166,109 (-)NCBIHuRef
CHM1_13164,659,546 - 164,759,127 (-)NCBICHM1_1
Sis
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39372,795,890 - 72,875,196 (-)NCBIGRCm39mm39
GRCm39 Ensembl372,795,890 - 72,875,196 (-)Ensembl
GRCm38372,888,557 - 72,967,863 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl372,888,557 - 72,967,863 (-)EnsemblGRCm38mm10GRCm38
MGSCv37372,692,482 - 72,770,788 (-)NCBIGRCm37mm9NCBIm37
MGSCv36372,976,489 - 73,055,789 (-)NCBImm8
Celera373,012,488 - 73,086,863 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map332.59NCBI
Si
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22157,505,893 - 157,586,228 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl2170,221,245 - 170,301,348 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02170,220,794 - 170,301,348 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02189,563,145 - 189,643,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42163,520,975 - 163,601,280 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12163,470,937 - 163,551,243 (-)NCBI
Celera2151,764,945 - 151,845,208 (-)NCBICelera
RH 3.4 Map21027.6RGD
Cytogenetic Map2q32NCBI
Si
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544814,685,963 - 14,777,338 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544814,686,315 - 14,777,298 (-)NCBIChiLan1.0ChiLan1.0
SI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13170,057,282 - 170,156,983 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3170,057,750 - 170,154,502 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03161,961,038 - 162,104,054 (-)NCBIMhudiblu_PPA_v0panPan3
SI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13430,284,869 - 30,373,749 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3430,284,858 - 30,373,780 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3439,346,430 - 39,434,804 (-)NCBI
ROS_Cfam_1.03430,347,263 - 30,435,400 (-)NCBI
UMICH_Zoey_3.13430,290,443 - 30,378,872 (-)NCBI
UNSW_CanFamBas_1.03430,241,911 - 30,330,433 (-)NCBI
UU_Cfam_GSD_1.03430,511,922 - 30,599,883 (-)NCBI
Si
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560296,367,610 - 96,445,267 (-)NCBI
SpeTri2.0NW_0049367071,153,538 - 1,228,220 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11524,480,060 - 24,582,468 (+)NCBI
ChlSab1.1 Ensembl1524,482,865 - 24,582,394 (+)Ensembl
Vero_WHO_p1.0NW_02366606333,458,175 - 33,557,570 (+)NCBI
Si
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473042,984,277 - 43,112,819 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system nervous system
High
Medium 6
Low 2 2
Below cutoff 2 1 18

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000032326   ⟹   ENSSSCP00000023767
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13104,296,283 - 104,379,478 (-)Ensembl
RefSeq Acc Id: XM_021069748   ⟹   XP_020925407
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113104,296,281 - 104,379,558 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069749   ⟹   XP_020925408
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113104,296,281 - 104,379,500 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069750   ⟹   XP_020925409
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113104,296,281 - 104,379,478 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069751   ⟹   XP_020925410
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113104,296,281 - 104,379,500 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020925407 (Get FASTA)   NCBI Sequence Viewer  
  XP_020925408 (Get FASTA)   NCBI Sequence Viewer  
  XP_020925409 (Get FASTA)   NCBI Sequence Viewer  
  XP_020925410 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein P56729 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020925407   ⟸   XM_021069748
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020925408   ⟸   XM_021069749
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020925410   ⟸   XM_021069751
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020925409   ⟸   XM_021069750
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000023767   ⟸   ENSSSCT00000032326
Protein Domains
P-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011735 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070023971 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000023767 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070040383 UniProtKB/TrEMBL
  ENSSSCP00070040405 UniProtKB/TrEMBL
  ENSSSCP00070040410 UniProtKB/TrEMBL
  ENSSSCP00070040417 UniProtKB/TrEMBL
  ENSSSCP00070040425 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000032326 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070047848 UniProtKB/TrEMBL
  ENSSSCT00070047874 UniProtKB/TrEMBL
  ENSSSCT00070047880 UniProtKB/TrEMBL
  ENSSSCT00070047888 UniProtKB/TrEMBL
  ENSSSCT00070047896 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1180 UniProtKB/TrEMBL
InterPro Gal_mutarotase_N UniProtKB/TrEMBL
  Gal_mutarotase_sf_dom UniProtKB/TrEMBL
  Glyco_hydro_31 UniProtKB/TrEMBL
  Glyco_hydro_31_AS UniProtKB/TrEMBL
  Glyco_hydro_31_CS UniProtKB/TrEMBL
  Glyco_hydro_b UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
  P_trefoil_CS UniProtKB/TrEMBL
  P_trefoil_dom UniProtKB/TrEMBL
NCBI Gene SI ENTREZGENE
Pfam Glyco_hydro_31 UniProtKB/TrEMBL
  NtCtMGAM_N UniProtKB/TrEMBL
  Trefoil UniProtKB/TrEMBL
PROSITE GLYCOSYL_HYDROL_F31_1 UniProtKB/TrEMBL
  GLYCOSYL_HYDROL_F31_2 UniProtKB/TrEMBL
  P_TREFOIL_1 UniProtKB/TrEMBL
  P_TREFOIL_2 UniProtKB/TrEMBL
SMART SM00018 UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/TrEMBL
  SSF74650 UniProtKB/TrEMBL
UniProt A0A4X1VBC4_PIG UniProtKB/TrEMBL
  A0A4X1VHU5_PIG UniProtKB/TrEMBL
  A0A4X1VHW3_PIG UniProtKB/TrEMBL
  A0A4X1VHW8_PIG UniProtKB/TrEMBL
  A0A4X1VHY7_PIG UniProtKB/TrEMBL
  I3LI68_PIG UniProtKB/TrEMBL
  P56729 ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID VGNC:92863 ENTREZGENE