DOC2B (double C2 domain beta) - Rat Genome Database
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Gene: DOC2B (double C2 domain beta) Sus scrofa
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Symbol: DOC2B
Name: double C2 domain beta
RGD ID: 14224603
Description: ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent phospholipid binding (inferred); syntaxin binding (inferred); INVOLVED IN exocytosis (ortholog); positive regulation of calcium ion-dependent exocytosis (ortholog); positive regulation of vesicle fusion (ortholog); FOUND IN SNARE complex (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: double C2-like domain-containing protein beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,529,566 - 47,562,373 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,529,383 - 47,558,236 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
DOC2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,529,566 - 47,562,373 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,529,383 - 47,558,236 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DOC2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl17142,789 - 181,650 (-)EnsemblGRCh38hg38GRCh38
GRCh3817142,789 - 181,650 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37176,009 - 31,421 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36175,810 - 31,270 (-)NCBINCBI36hg18NCBI36
Celera1796,907 - 129,072 (-)NCBI
Cytogenetic Map17p13.3NCBI
HuRef1715,749 - 39,198 (-)NCBIHuRef
CHM1_11716,004 - 40,168 (-)NCBICHM1_1
Doc2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,659,096 - 75,686,886 (-)NCBIGRCm39mm39
GRCm381175,768,270 - 75,796,060 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,768,966 - 75,796,049 (-)EnsemblGRCm38mm10GRCm38
MGSCv371175,582,592 - 75,609,559 (-)NCBIGRCm37mm9NCBIm37
MGSCv361175,585,285 - 75,612,252 (-)NCBImm8
Celera1183,278,304 - 83,305,458 (-)NCBICelera
Cytogenetic Map11B5NCBI
Doc2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01063,921,255 - 63,952,944 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1063,928,064 - 63,952,726 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01064,053,913 - 64,078,844 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41063,115,782 - 63,140,805 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11063,129,404 - 63,154,428 (-)NCBI
Celera1059,653,415 - 59,678,192 (-)NCBICelera
Cytogenetic Map10q24NCBI
Doc2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554811,842,815 - 1,860,374 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554811,839,894 - 1,859,733 (-)NCBIChiLan1.0ChiLan1.0
DOC2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11780,050 - 123,659 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01719,854 - 58,336 (-)NCBIMhudiblu_PPA_v0panPan3
DOC2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl945,450,302 - 45,485,247 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1945,450,270 - 45,488,638 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Doc2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365387,461,030 - 7,486,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DOC2B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1619,294 - 49,309 (-)Ensembl
ChlSab1.11617,890 - 51,080 (-)NCBI
Doc2b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247864,029,384 - 4,060,676 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 3 2 1 4 17 2
Below cutoff 3 2 1 1 5 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000047908   ⟹   ENSSSCP00000055973
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1247,529,566 - 47,562,373 (+)Ensembl
RefSeq Acc Id: XM_021067535   ⟹   XP_020923194
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11247,529,383 - 47,558,236 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021067536   ⟹   XP_020923195
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11247,537,451 - 47,558,236 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020923194 (Get FASTA)   NCBI Sequence Viewer  
  XP_020923195 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020923194   ⟸   XM_021067535
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020923195   ⟸   XM_021067536
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000055973   ⟸   ENSSSCT00000047908
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000039412 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070014248 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000055973 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070023232 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000047908 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070027907 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Doc2 UniProtKB/TrEMBL
  Doc2b UniProtKB/TrEMBL
  Rabphilin/DOC2/Noc2 UniProtKB/TrEMBL
  Synaptotagmin UniProtKB/TrEMBL
NCBI Gene DOC2B ENTREZGENE
PANTHER PTHR45729 UniProtKB/TrEMBL
  PTHR45729:SF9 UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
PIRSF Doc2 UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
  SYNAPTOTAGMN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
UniProt A0A287BHY3_PIG UniProtKB/TrEMBL
  A0A4X1U5A0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87389 ENTREZGENE