NTF4 (neurotrophin 4) - Rat Genome Database

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Gene: NTF4 (neurotrophin 4) Sus scrofa
Analyze
Symbol: NTF4
Name: neurotrophin 4
RGD ID: 14223177
Description: ENCODES a protein that exhibits growth factor activity (inferred); signaling receptor binding (inferred); INVOLVED IN adult locomotory behavior (ortholog); epidermis development (ortholog); ganglion mother cell fate determination (ortholog); ASSOCIATED WITH asthma (ortholog); autistic disorder (ortholog); developmental and epileptic encephalopathy 12 (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: neurotrophin-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,271,246 - 54,274,092 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,271,244 - 54,288,846 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,039,657 - 50,057,398 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
NTF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,271,246 - 54,274,092 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,271,244 - 54,288,846 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,039,657 - 50,057,398 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NTF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,058,284 - 49,065,035 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1949,061,066 - 49,065,076 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,564,385 - 49,568,292 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,256,209 - 54,260,047 (-)NCBINCBI36hg18NCBI36
Build 341954,256,210 - 54,258,937NCBI
Celera1946,431,605 - 46,435,443 (-)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1945,941,069 - 45,943,797 (-)NCBIHuRef
CHM1_11949,566,638 - 49,569,366 (-)NCBICHM1_1
T2T-CHM13v2.01952,055,917 - 52,059,823 (-)NCBI
Ntf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,063,119 - 45,066,603 (+)NCBIGRCm39mm39
GRCm39 Ensembl745,063,119 - 45,066,603 (+)Ensembl
GRCm38745,413,695 - 45,417,179 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,413,695 - 45,417,179 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,669,065 - 52,672,549 (+)NCBIGRCm37mm9NCBIm37
MGSCv36745,281,737 - 45,285,221 (+)NCBImm8
Celera740,869,726 - 40,873,213 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.3NCBI
Ntf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2195,893,560 - 95,896,391 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl195,893,457 - 95,897,243 (+)Ensembl
Rnor_6.01101,405,314 - 101,408,145 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,405,314 - 101,408,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,484,724 - 102,487,555 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,885,577 - 95,888,408 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1195,963,687 - 95,966,519 (+)NCBI
Celera190,149,153 - 90,151,984 (+)NCBICelera
RH 3.4 Map1909.3RGD
Cytogenetic Map1q22NCBI
Ntf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,647,685 - 1,650,553 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,647,685 - 1,650,553 (+)NCBIChiLan1.0ChiLan1.0
LOC103785360
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11954,994,710 - 55,010,424 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,995,009 - 54,995,641 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01946,041,053 - 46,041,808 (-)NCBIMhudiblu_PPA_v0panPan3
NTF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,371,335 - 107,377,238 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,371,335 - 107,376,987 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01107,895,849 - 107,901,840 (+)NCBI
ROS_Cfam_1.0 Ensembl1107,895,849 - 107,901,548 (+)Ensembl
UMICH_Zoey_3.11107,563,703 - 107,569,398 (+)NCBI
UNSW_CanFamBas_1.01107,209,908 - 107,215,558 (+)NCBI
UU_Cfam_GSD_1.01108,045,520 - 108,051,170 (+)NCBI
Ntf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,398,887 - 21,401,144 (-)NCBI
SpeTri2.0NW_0049366643,017,108 - 3,017,955 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NTF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,254,693 - 42,284,899 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl642,279,190 - 42,279,822 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607322,170,689 - 22,171,841 (-)NCBIVero_WHO_p1.0
Ntf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,007,801 - 5,008,451 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248325,005,935 - 5,008,694 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system reproductive system respiratory system
High
Medium
Low 2 2 3 2 9 2
Below cutoff 5 1 2 10 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000003510   ⟹   ENSSSCP00000003427
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl654,271,246 - 54,274,092 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000079549   ⟹   ENSSSCP00000062381
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl654,270,553 - 54,288,843 (-)Ensembl
RefSeq Acc Id: NM_001243713   ⟹   NP_001230642
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,271,244 - 54,274,092 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013998616   ⟹   XP_013854070
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,271,244 - 54,288,846 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013998617   ⟹   XP_013854071
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,271,244 - 54,273,885 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001230642 (Get FASTA)   NCBI Sequence Viewer  
  XP_013854070 (Get FASTA)   NCBI Sequence Viewer  
  XP_013854071 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013854070   ⟸   XM_013998616
- Peptide Label: isoform X1
- UniProtKB: F1RIN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230642   ⟸   NM_001243713
- Peptide Label: precursor
- UniProtKB: F1RIN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013854071   ⟸   XM_013998617
- Peptide Label: isoform X1
- UniProtKB: F1RIN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000062381   ⟸   ENSSSCT00000079549
RefSeq Acc Id: ENSSSCP00000003427   ⟸   ENSSSCT00000003510
Protein Domains
NGF


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000003160 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015015859 UniProtKB/TrEMBL
  ENSSSCG00025020267 UniProtKB/TrEMBL
  ENSSSCG00030064963 UniProtKB/TrEMBL
  ENSSSCG00035039077 UniProtKB/TrEMBL
  ENSSSCG00040014558 UniProtKB/TrEMBL
  ENSSSCG00045012793 UniProtKB/TrEMBL
  ENSSSCG00050077239 UniProtKB/TrEMBL
  ENSSSCG00055006911 UniProtKB/TrEMBL
  ENSSSCG00060078089 UniProtKB/TrEMBL
  ENSSSCG00065054342 UniProtKB/TrEMBL
  ENSSSCG00070027707 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000003427 ENTREZGENE
  ENSSSCP00000003427.2 UniProtKB/TrEMBL
  ENSSSCP00000062381.1 UniProtKB/TrEMBL
  ENSSSCP00015008268.1 UniProtKB/TrEMBL
  ENSSSCP00025011648.1 UniProtKB/TrEMBL
  ENSSSCP00030041797.1 UniProtKB/TrEMBL
  ENSSSCP00035020824.1 UniProtKB/TrEMBL
  ENSSSCP00040008087.1 UniProtKB/TrEMBL
  ENSSSCP00045014984.1 UniProtKB/TrEMBL
  ENSSSCP00050046914.1 UniProtKB/TrEMBL
  ENSSSCP00055010520.1 UniProtKB/TrEMBL
  ENSSSCP00060047779.1 UniProtKB/TrEMBL
  ENSSSCP00060047780.1 UniProtKB/TrEMBL
  ENSSSCP00065032423.1 UniProtKB/TrEMBL
  ENSSSCP00070047198.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000003510 ENTREZGENE
  ENSSSCT00000003510.3 UniProtKB/TrEMBL
  ENSSSCT00000079549.1 UniProtKB/TrEMBL
  ENSSSCT00015021036.1 UniProtKB/TrEMBL
  ENSSSCT00025027515.1 UniProtKB/TrEMBL
  ENSSSCT00030090768.1 UniProtKB/TrEMBL
  ENSSSCT00035051877.1 UniProtKB/TrEMBL
  ENSSSCT00040019501.1 UniProtKB/TrEMBL
  ENSSSCT00045021778.1 UniProtKB/TrEMBL
  ENSSSCT00050106286.1 UniProtKB/TrEMBL
  ENSSSCT00055013378.1 UniProtKB/TrEMBL
  ENSSSCT00060107683.1 UniProtKB/TrEMBL
  ENSSSCT00060107684.1 UniProtKB/TrEMBL
  ENSSSCT00065074427.1 UniProtKB/TrEMBL
  ENSSSCT00070055576.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  Nerve_growth_factor-like UniProtKB/TrEMBL
  Nerve_growth_factor-rel UniProtKB/TrEMBL
  Nerve_growth_factor_CS UniProtKB/TrEMBL
  Neurotrophin-4 UniProtKB/TrEMBL
KEGG Report ssc:100511085 UniProtKB/TrEMBL
NCBI Gene NTF4 ENTREZGENE
PANTHER PTHR11589 UniProtKB/TrEMBL
  PTHR11589:SF8 UniProtKB/TrEMBL
Pfam NGF UniProtKB/TrEMBL
PIRSF NGF UniProtKB/TrEMBL
PRINTS NEUROTROPHN4 UniProtKB/TrEMBL
  NGF UniProtKB/TrEMBL
PROSITE NGF_1 UniProtKB/TrEMBL
SMART NGF UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A4X1VZW4_PIG UniProtKB/TrEMBL
  F1RIN3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:98163 ENTREZGENE