DYNC2LI1 (dynein cytoplasmic 2 light intermediate chain 1) - Rat Genome Database

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Gene: DYNC2LI1 (dynein cytoplasmic 2 light intermediate chain 1) Sus scrofa
Analyze
Symbol: DYNC2LI1
Name: dynein cytoplasmic 2 light intermediate chain 1
RGD ID: 14213570
Description: ENCODES a protein that exhibits dynein heavy chain binding (inferred); INVOLVED IN cilium assembly (ortholog); determination of left/right symmetry (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); genetic disease (ortholog); FOUND IN apical part of cell (inferred); axoneme (inferred); centrosome (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cytoplasmic dynein 2 light intermediate chain 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl396,654,415 - 96,703,237 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1396,656,099 - 96,703,282 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X142,093,233 - 142,093,545 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:15679890   PMID:30032202  


Genomics

Comparative Map Data
DYNC2LI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl396,654,415 - 96,703,237 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1396,656,099 - 96,703,282 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X142,093,233 - 142,093,545 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DYNC2LI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38243,774,039 - 43,828,347 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl243,774,039 - 43,810,010 (+)EnsemblGRCh38hg38GRCh38
GRCh37244,001,178 - 44,055,486 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36243,854,686 - 43,890,653 (+)NCBINCBI36Build 36hg18NCBI36
Celera243,839,914 - 43,875,885 (+)NCBICelera
Cytogenetic Map2p21NCBI
HuRef243,737,874 - 43,773,845 (+)NCBIHuRef
CHM1_1243,930,576 - 43,966,546 (+)NCBICHM1_1
T2T-CHM13v2.0243,779,369 - 43,833,678 (+)NCBIT2T-CHM13v2.0
Dync2li1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391784,933,903 - 84,962,996 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1784,933,924 - 84,963,016 (+)EnsemblGRCm39 Ensembl
GRCm381784,626,475 - 84,655,568 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1784,626,496 - 84,655,588 (+)EnsemblGRCm38mm10GRCm38
MGSCv371785,025,836 - 85,054,908 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361784,534,823 - 84,563,894 (+)NCBIMGSCv36mm8
Celera1788,993,647 - 89,022,328 (+)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1755.02NCBI
Dync2li1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8615,745,350 - 15,778,166 (-)NCBIGRCr8
mRatBN7.269,992,537 - 10,025,355 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl69,992,541 - 10,025,336 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx610,287,813 - 10,320,761 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0610,597,204 - 10,630,152 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0610,112,319 - 10,148,463 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.067,900,962 - 7,933,795 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl67,900,972 - 7,933,796 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.067,837,898 - 7,869,293 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.467,993,577 - 8,025,670 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.167,993,576 - 8,025,669 (+)NCBI
Celera69,714,091 - 9,746,141 (-)NCBICelera
Cytogenetic Map6q12NCBI
Dync2li1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544110,928,343 - 10,961,194 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544110,928,577 - 10,961,194 (+)NCBIChiLan1.0ChiLan1.0
DYNC2LI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21282,595,156 - 82,649,760 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A82,599,634 - 82,653,716 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A43,858,368 - 43,912,262 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A44,706,777 - 44,760,757 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A44,706,777 - 44,742,724 (+)Ensemblpanpan1.1panPan2
DYNC2LI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11046,231,433 - 46,270,102 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1046,231,460 - 46,290,382 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1046,093,044 - 46,131,740 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01047,109,916 - 47,148,612 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1047,109,962 - 47,148,583 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11046,818,280 - 46,856,971 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01047,108,466 - 47,146,902 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01047,291,618 - 47,330,309 (+)NCBIUU_Cfam_GSD_1.0
Dync2li1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629236,690,889 - 36,720,417 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365088,118,589 - 8,149,035 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365088,119,733 - 8,149,022 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNC2LI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11463,441,948 - 63,481,460 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1463,440,155 - 63,481,479 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604548,407,629 - 48,448,000 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dync2li1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473825,245,890 - 25,283,706 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473825,245,792 - 25,298,397 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DYNC2LI1
886 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 3 6 2 2
Low 8 4 5 2 17 1 2
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000056975   ⟹   ENSSSCP00000043950
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl396,654,415 - 96,703,219 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000065558   ⟹   ENSSSCP00000045158
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl396,659,249 - 96,703,237 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000066504   ⟹   ENSSSCP00000065607
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl396,656,280 - 96,689,324 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000091151   ⟹   ENSSSCP00000060003
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl396,670,947 - 96,703,237 (-)Ensembl
RefSeq Acc Id: NM_001244749   ⟹   NP_001231678
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1396,656,099 - 96,703,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085661   ⟹   XP_020941320
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1396,656,279 - 96,703,282 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021085662   ⟹   XP_020941321
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1396,656,279 - 96,703,282 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001231678   ⟸   NM_001244749
- UniProtKB: A0A287AJ83 (UniProtKB/TrEMBL),   A0A480JTX3 (UniProtKB/TrEMBL),   A0A4X1SKQ0 (UniProtKB/TrEMBL),   A0A8D1JVJ4 (UniProtKB/TrEMBL),   A0A8D0LKK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941321   ⟸   XM_021085662
- Peptide Label: isoform X2
- UniProtKB: A0A8D1D9W4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941320   ⟸   XM_021085661
- Peptide Label: isoform X1
- UniProtKB: A0A287AJ83 (UniProtKB/TrEMBL),   A0A8D1JVJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000045158   ⟸   ENSSSCT00000065558
RefSeq Acc Id: ENSSSCP00000043950   ⟸   ENSSSCT00000056975
RefSeq Acc Id: ENSSSCP00000065607   ⟸   ENSSSCT00000066504
RefSeq Acc Id: ENSSSCP00000060003   ⟸   ENSSSCT00000091151


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038383 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005016338 UniProtKB/TrEMBL
  ENSSSCG00025028273 UniProtKB/TrEMBL
  ENSSSCG00030033052 UniProtKB/TrEMBL
  ENSSSCG00035061852 UniProtKB/TrEMBL
  ENSSSCG00040007292 UniProtKB/TrEMBL
  ENSSSCG00050012739 UniProtKB/TrEMBL
  ENSSSCG00065042895 UniProtKB/TrEMBL
  ENSSSCG00070001937 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000056975 ENTREZGENE
  ENSSSCT00000056975.3 UniProtKB/TrEMBL
  ENSSSCT00000065558.3 UniProtKB/TrEMBL
  ENSSSCT00000066504 ENTREZGENE
  ENSSSCT00000066504.1 UniProtKB/TrEMBL
  ENSSSCT00000091151.2 UniProtKB/TrEMBL
  ENSSSCT00005025722.1 UniProtKB/TrEMBL
  ENSSSCT00005025791.1 UniProtKB/TrEMBL
  ENSSSCT00005025828.1 UniProtKB/TrEMBL
  ENSSSCT00005025910.1 UniProtKB/TrEMBL
  ENSSSCT00025038491.1 UniProtKB/TrEMBL
  ENSSSCT00025038581.1 UniProtKB/TrEMBL
  ENSSSCT00030045785.1 UniProtKB/TrEMBL
  ENSSSCT00030045844.1 UniProtKB/TrEMBL
  ENSSSCT00035083119.1 UniProtKB/TrEMBL
  ENSSSCT00040009614.1 UniProtKB/TrEMBL
  ENSSSCT00040009657.1 UniProtKB/TrEMBL
  ENSSSCT00050017200.1 UniProtKB/TrEMBL
  ENSSSCT00050017208.1 UniProtKB/TrEMBL
  ENSSSCT00065058666.1 UniProtKB/TrEMBL
  ENSSSCT00070003642.1 UniProtKB/TrEMBL
  ENSSSCT00070003657.1 UniProtKB/TrEMBL
  ENSSSCT00070003667.1 UniProtKB/TrEMBL
InterPro DYNC2LI1 UniProtKB/TrEMBL
  Dynein_light_int_chain UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report ssc:100513078 UniProtKB/TrEMBL
NCBI Gene DYNC2LI1 ENTREZGENE
PANTHER CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1 UniProtKB/TrEMBL
  PTHR13236 UniProtKB/TrEMBL
Pfam DLIC UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287AJ83 ENTREZGENE, UniProtKB/TrEMBL
  A0A480JTX3 ENTREZGENE
  A0A4X1SKQ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SM20_PIG UniProtKB/TrEMBL
  A0A5G2QUG0_PIG UniProtKB/TrEMBL
  A0A8D0LJY6_PIG UniProtKB/TrEMBL
  A0A8D0LKK3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1D9W4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1JVJ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1YTZ9_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287AMP5 UniProtKB/TrEMBL
  A0A480JTX3 UniProtKB/TrEMBL
  A0A5G2Q9L3 UniProtKB/TrEMBL
VGNC ID VGNC:87499 ENTREZGENE