POU6F2 (POU class 6 homeobox 2) - Rat Genome Database

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Gene: POU6F2 (POU class 6 homeobox 2) Sus scrofa
Analyze
Symbol: POU6F2
Name: POU class 6 homeobox 2
RGD ID: 14212509
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); hypogonadism (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: POU domain, class 6, transcription factor 2; retina-derived POU-domain factor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1854,748,790 - 55,231,511 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11854,744,833 - 55,231,628 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21860,023,190 - 60,495,998 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:14681463   PMID:30032202  


Genomics

Comparative Map Data
POU6F2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1854,748,790 - 55,231,511 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11854,744,833 - 55,231,628 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21860,023,190 - 60,495,998 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POU6F2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38738,977,909 - 39,468,601 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl738,977,909 - 39,493,095 (+)EnsemblGRCh38hg38GRCh38
GRCh37739,017,509 - 39,508,200 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36739,012,933 - 39,470,915 (+)NCBINCBI36Build 36hg18NCBI36
Build 34738,819,647 - 39,277,630NCBI
Celera739,005,468 - 39,491,972 (+)NCBICelera
Cytogenetic Map7p14.1NCBI
HuRef738,901,808 - 39,131,455 (+)NCBIHuRef
HuRef739,263,229 - 39,387,744 (+)NCBIHuRef
CHM1_1739,020,250 - 39,507,035 (+)NCBICHM1_1
T2T-CHM13v2.0739,134,935 - 39,626,147 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2739,055,332 - 39,542,296 (+)NCBI
Pou6f2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391318,295,683 - 18,797,703 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1318,295,683 - 18,572,271 (-)EnsemblGRCm39 Ensembl
GRCm381318,124,960 - 18,382,044 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1318,121,098 - 18,397,686 (-)EnsemblGRCm38mm10GRCm38
MGSCv371318,216,794 - 18,473,878 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361318,132,390 - 18,389,469 (-)NCBIMGSCv36mm8
Celera1318,429,425 - 18,804,175 (-)NCBICelera
Cytogenetic Map13A2NCBI
cM Map136.05NCBI
Pou6f2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81751,040,522 - 51,616,716 (+)NCBIGRCr8
mRatBN7.21746,472,182 - 46,886,796 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1746,472,181 - 46,921,039 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01749,053,679 - 49,509,174 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01747,511,833 - 47,565,068 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01747,109,121 - 47,393,004 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41754,329,459 - 54,801,954 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1742,568,123 - 43,015,078 (+)NCBICelera
Cytogenetic Map17q11NCBI
Pou6f2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554604,021,679 - 4,497,538 (-)NCBIChiLan1.0ChiLan1.0
POU6F2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2643,812,289 - 44,303,364 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1792,137,024 - 92,628,099 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0739,613,073 - 40,104,152 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1739,846,706 - 40,330,980 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl739,875,708 - 40,330,667 (+)Ensemblpanpan1.1panPan2
POU6F2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11810,237,802 - 10,293,108 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1810,081,229 - 10,206,894 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01810,282,833 - 10,407,490 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11810,259,675 - 10,385,984 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01810,234,925 - 10,360,761 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01810,343,344 - 10,469,200 (-)NCBIUU_Cfam_GSD_1.0
Pou6f2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511895,307,474 - 95,764,439 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647814,614,635 - 14,972,204 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103226192
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12119,070,826 - 19,563,011 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660622,856,319 - 3,051,636 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pou6f2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474021,512,810 - 21,961,131 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in POU6F2
15900 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system respiratory system
High
Medium
Low 1 3 2 8
Below cutoff 4 1 2 7 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000038955   ⟹   ENSSSCP00000034687
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1854,748,790 - 55,231,511 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000043214   ⟹   ENSSSCP00000033338
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1854,748,790 - 55,205,561 (-)Ensembl
RefSeq Acc Id: XM_013985842   ⟹   XP_013841296
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11854,744,833 - 55,231,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021079083   ⟹   XP_020934742
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11854,744,833 - 55,231,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021079084   ⟹   XP_020934743
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11854,744,833 - 55,230,932 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002340448
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11855,181,520 - 55,230,958 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002340449
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11855,181,520 - 55,230,959 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002340450
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11855,181,520 - 55,230,955 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002340451
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11855,181,520 - 55,230,949 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002340452
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11855,181,520 - 55,230,955 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020934742   ⟸   XM_021079083
- Peptide Label: isoform X2
- UniProtKB: A0A286ZSS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013841296   ⟸   XM_013985842
- Peptide Label: isoform X1
- UniProtKB: A0A286ZSS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020934743   ⟸   XM_021079084
- Peptide Label: isoform X3
- UniProtKB: A0A286ZP28 (UniProtKB/TrEMBL),   A0A4X1ULR8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000034687   ⟸   ENSSSCT00000038955
RefSeq Acc Id: ENSSSCP00000033338   ⟸   ENSSSCT00000043214
Protein Domains
Homeobox   POU-specific


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037764 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025068052 UniProtKB/TrEMBL
  ENSSSCG00035049924 UniProtKB/TrEMBL
  ENSSSCG00040068547 UniProtKB/TrEMBL
  ENSSSCG00055004158 UniProtKB/TrEMBL
  ENSSSCG00070017799 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000038955 ENTREZGENE
  ENSSSCT00000038955.3 UniProtKB/TrEMBL
  ENSSSCT00000043214 ENTREZGENE
  ENSSSCT00000043214.2 UniProtKB/TrEMBL
  ENSSSCT00025093685.1 UniProtKB/TrEMBL
  ENSSSCT00035066541.1 UniProtKB/TrEMBL
  ENSSSCT00040094295.1 UniProtKB/TrEMBL
  ENSSSCT00055008207.1 UniProtKB/TrEMBL
  ENSSSCT00070035147.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.260.40 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Lambda_DNA-bd_dom_sf UniProtKB/TrEMBL
  POU UniProtKB/TrEMBL
  POU_dom UniProtKB/TrEMBL
NCBI Gene POU6F2 ENTREZGENE
PANTHER POU DOMAIN UniProtKB/TrEMBL
  PTHR11636:SF68 UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
  Pou UniProtKB/TrEMBL
PRINTS POUDOMAIN UniProtKB/TrEMBL
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
  POU_1 UniProtKB/TrEMBL
  POU_2 UniProtKB/TrEMBL
  POU_3 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  POU UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
  SSF47413 UniProtKB/TrEMBL
UniProt A0A286ZP28 ENTREZGENE, UniProtKB/TrEMBL
  A0A286ZSS7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1ULR8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:98207 ENTREZGENE