DRC1 (dynein regulatory complex subunit 1) - Rat Genome Database

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Gene: DRC1 (dynein regulatory complex subunit 1) Sus scrofa
Analyze
Symbol: DRC1
Name: dynein regulatory complex subunit 1
RGD ID: 14211130
Description: INVOLVED IN axoneme assembly (ortholog); cilium organization (ortholog); cilium-dependent cell motility (ortholog); ASSOCIATED WITH genetic disease (ortholog); Kartagener syndrome (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cilium (ortholog); cytosol (ortholog); sperm flagellum (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dynein regulatory complex protein 1; dynein regulatory complex subunit 1 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3112,581,779 - 112,621,623 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13112,581,765 - 112,621,664 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,717,738 - 119,744,054 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axonemal dynein complex  (IEA)
axoneme  (IBA,IEA)
cilium  (ISO)
cytosol  (IEA,ISO)
motile cilium  (IEA)
sperm flagellum  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DRC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3112,581,779 - 112,621,623 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13112,581,765 - 112,621,664 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,717,738 - 119,744,054 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DRC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38226,401,920 - 26,456,711 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl226,401,920 - 26,456,711 (+)EnsemblGRCh38hg38GRCh38
GRCh37226,624,788 - 26,679,579 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,478,288 - 26,533,082 (+)NCBINCBI36Build 36hg18NCBI36
Celera226,468,325 - 26,523,128 (+)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef226,363,993 - 26,418,785 (+)NCBIHuRef
CHM1_1226,555,024 - 26,609,743 (+)NCBICHM1_1
T2T-CHM13v2.0226,440,521 - 26,495,334 (+)NCBIT2T-CHM13v2.0
Drc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39530,486,328 - 30,524,039 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl530,486,386 - 30,524,039 (+)EnsemblGRCm39 Ensembl
GRCm38530,281,335 - 30,366,695 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl530,281,388 - 30,366,695 (+)EnsemblGRCm38mm10GRCm38
MGSCv37530,643,988 - 30,668,993 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36530,643,988 - 30,668,993 (+)NCBIMGSCv36mm8
Celera527,800,480 - 27,842,753 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map516.42NCBI
Drc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,744,849 - 31,779,996 (-)NCBIGRCr8
mRatBN7.2626,025,004 - 26,059,438 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl626,025,005 - 26,059,414 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx626,317,636 - 26,352,052 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0626,633,519 - 26,667,934 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0626,112,990 - 26,147,339 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0627,425,237 - 27,460,038 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,425,235 - 27,460,038 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0637,237,528 - 37,272,329 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,009,319 - 26,044,919 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1626,012,272 - 26,047,872 (-)NCBI
Celera625,502,874 - 25,536,310 (-)NCBICelera
Cytogenetic Map6q14NCBI
Drc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554698,417,017 - 8,479,802 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554698,416,934 - 8,479,961 (+)NCBIChiLan1.0ChiLan1.0
DRC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212100,060,617 - 100,114,624 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A100,064,585 - 100,118,591 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A26,399,275 - 26,453,518 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A26,491,900 - 26,545,640 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A26,491,900 - 26,545,640 (+)Ensemblpanpan1.1panPan2
DRC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11720,479,290 - 20,517,960 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1720,431,176 - 20,517,753 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1720,374,176 - 20,412,428 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01720,801,323 - 20,839,755 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1720,800,870 - 20,839,548 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11720,488,044 - 20,526,500 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01720,499,051 - 20,537,662 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01720,545,418 - 20,583,914 (+)NCBIUU_Cfam_GSD_1.0
Drc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629264,796,133 - 64,838,684 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364936,000,165 - 6,043,455 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364936,000,881 - 6,043,437 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11481,188,261 - 81,245,064 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604530,908,542 - 30,963,901 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Drc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247388,541,063 - 8,599,491 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247388,540,863 - 8,599,386 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DRC1
2009 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system
High
Medium
Low 1 2 3 2 13 1 2
Below cutoff 5 1 1 1 6 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000009374   ⟹   ENSSSCP00000009134
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl3112,581,780 - 112,621,623 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000093447   ⟹   ENSSSCP00000077139
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl3112,581,779 - 112,612,228 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000097584   ⟹   ENSSSCP00000078285
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl3112,584,016 - 112,621,623 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000101248   ⟹   ENSSSCP00000078774
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl3112,584,016 - 112,621,623 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000106251   ⟹   ENSSSCP00000076278
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl3112,581,779 - 112,612,228 (-)Ensembl
RefSeq Acc Id: XM_021087730   ⟹   XP_020943389
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.13112,581,765 - 112,621,664 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021087732   ⟹   XP_020943391
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.13112,581,765 - 112,621,617 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020943389   ⟸   XM_021087730
- Peptide Label: isoform X1
- UniProtKB: A0A8W4FGC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020943391   ⟸   XM_021087732
- Peptide Label: isoform X2
- UniProtKB: A0A8W4FCZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000009134   ⟸   ENSSSCT00000009374
RefSeq Acc Id: ENSSSCP00000078774   ⟸   ENSSSCT00000101248
RefSeq Acc Id: ENSSSCP00000077139   ⟸   ENSSSCT00000093447
RefSeq Acc Id: ENSSSCP00000076278   ⟸   ENSSSCT00000106251
RefSeq Acc Id: ENSSSCP00000078285   ⟸   ENSSSCT00000097584
Protein Domains
Dynein regulatory complex protein 1 C-terminal   Dynein regulatory complex protein 1/2 N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008568 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025060727 UniProtKB/TrEMBL
  ENSSSCG00035070731 UniProtKB/TrEMBL
  ENSSSCG00045004530 UniProtKB/TrEMBL
  ENSSSCG00055008077 UniProtKB/TrEMBL
  ENSSSCG00060048862 UniProtKB/TrEMBL
  ENSSSCG00065022571 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000009374 ENTREZGENE
  ENSSSCT00000009374.5 UniProtKB/TrEMBL
  ENSSSCT00000093447.1 UniProtKB/TrEMBL
  ENSSSCT00000097584.1 UniProtKB/TrEMBL
  ENSSSCT00000101248.1 UniProtKB/TrEMBL
  ENSSSCT00000106251.1 UniProtKB/TrEMBL
  ENSSSCT00025083143.1 UniProtKB/TrEMBL
  ENSSSCT00025083413.1 UniProtKB/TrEMBL
  ENSSSCT00035095591.1 UniProtKB/TrEMBL
  ENSSSCT00035095616.1 UniProtKB/TrEMBL
  ENSSSCT00045007513.1 UniProtKB/TrEMBL
  ENSSSCT00045007515.1 UniProtKB/TrEMBL
  ENSSSCT00055015747.1 UniProtKB/TrEMBL
  ENSSSCT00055015811.1 UniProtKB/TrEMBL
  ENSSSCT00060066364.1 UniProtKB/TrEMBL
  ENSSSCT00060066370.1 UniProtKB/TrEMBL
  ENSSSCT00065030029.1 UniProtKB/TrEMBL
  ENSSSCT00065030032.1 UniProtKB/TrEMBL
InterPro DRC1/2_N UniProtKB/TrEMBL
  DRC1/DRC2 UniProtKB/TrEMBL
  DRC1_C UniProtKB/TrEMBL
NCBI Gene DRC1 ENTREZGENE
PANTHER DYNEIN REGULATORY COMPLEX PROTEIN 1 UniProtKB/TrEMBL
  PTHR21625 UniProtKB/TrEMBL
Pfam NYD-SP28 UniProtKB/TrEMBL
  NYD-SP28_assoc UniProtKB/TrEMBL
UniProt A0A8D0SSS3_PIG UniProtKB/TrEMBL
  A0A8D1D3D3_PIG UniProtKB/TrEMBL
  A0A8D1VT98_PIG UniProtKB/TrEMBL
  A0A8D1Y1Q6_PIG UniProtKB/TrEMBL
  A0A8W4FBP8_PIG UniProtKB/TrEMBL
  A0A8W4FCZ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FGC0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FHH3_PIG UniProtKB/TrEMBL
  F1SDN3_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87440 ENTREZGENE