ESPNL (espin like) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: ESPNL (espin like) Sus scrofa
Analyze
Symbol: ESPNL
Name: espin like
RGD ID: 14208827
Description: ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); INVOLVED IN actin filament bundle assembly (inferred); sensory perception of sound (inferred); ASSOCIATED WITH Bethlem Myopathy 1A (ortholog); chromosome 2q37 deletion syndrome (ortholog); D-2-hydroxyglutaric aciduria 1 (ortholog); FOUND IN stereocilium tip (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: espin-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15137,675,710 - 137,706,662 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115137,674,867 - 137,706,968 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215152,084,342 - 152,114,957 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell projection  (IEA)
cytoplasm  (IBA,IEA)
stereocilium  (IEA)
stereocilium tip  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ESPNL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15137,675,710 - 137,706,662 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115137,674,867 - 137,706,968 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215152,084,342 - 152,114,957 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ESPNL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,100,340 - 238,133,287 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,100,340 - 238,133,287 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,008,981 - 239,041,928 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,673,690 - 238,706,667 (+)NCBINCBI36Build 36hg18NCBI36
Celera2232,721,894 - 232,754,471 (+)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2230,800,976 - 230,833,055 (+)NCBIHuRef
CHM1_12239,014,636 - 239,047,034 (+)NCBICHM1_1
T2T-CHM13v2.02238,590,236 - 238,623,038 (+)NCBIT2T-CHM13v2.0
Espnl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39191,249,845 - 91,277,130 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl191,249,797 - 91,276,028 (+)EnsemblGRCm39 Ensembl
GRCm38191,322,075 - 91,348,303 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl191,322,075 - 91,348,306 (+)EnsemblGRCm38mm10GRCm38
MGSCv37193,218,652 - 93,244,880 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36193,152,481 - 93,178,709 (+)NCBIMGSCv36mm8
Celera194,259,186 - 94,285,436 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map146.08NCBI
Espnl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8999,358,907 - 99,385,439 (+)NCBIGRCr8
mRatBN7.2991,912,038 - 91,936,803 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl991,912,049 - 91,935,292 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9100,338,818 - 100,362,060 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09105,474,578 - 105,497,820 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09103,838,173 - 103,861,427 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0998,459,175 - 98,484,930 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl998,460,177 - 98,483,419 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0998,136,139 - 98,161,479 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4990,547,266 - 90,570,761 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera989,453,359 - 89,476,315 (+)NCBICelera
Cytogenetic Map9q36NCBI
Espnl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555422,430,712 - 2,453,361 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555422,430,610 - 2,453,738 (-)NCBIChiLan1.0ChiLan1.0
ESPNL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213140,731,545 - 140,764,431 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B140,746,512 - 140,779,398 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B125,331,809 - 125,364,719 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B244,182,671 - 244,214,248 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B244,182,781 - 244,214,009 (+)Ensemblpanpan1.1panPan2
ESPNL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12548,609,340 - 48,634,397 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2549,105,311 - 49,132,935 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02548,995,197 - 49,023,042 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2548,995,158 - 49,021,659 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12548,870,291 - 48,897,694 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02548,658,916 - 48,686,318 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02548,891,219 - 48,918,851 (+)NCBIUU_Cfam_GSD_1.0
Espnl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303190,558,612 - 190,590,062 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936525352,389 - 380,214 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936525352,389 - 380,214 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESPNL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110124,122,495 - 124,152,355 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10124,123,379 - 124,152,127 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604075,265,583 - 75,295,437 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Espnl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248473,279,555 - 3,298,589 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248473,279,022 - 3,299,321 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ESPNL
1790 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

hemolymphoid system musculoskeletal system respiratory system
High
Medium
Low
Below cutoff 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017788   ⟹   ENSSSCP00000017307
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15137,675,710 - 137,706,662 (+)Ensembl
RefSeq Acc Id: XM_021074968   ⟹   XP_020930627
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115137,674,867 - 137,706,968 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020930627 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000017307
  ENSSSCP00000017307.4
  ENSSSCP00025046471.1
  ENSSSCP00035010939.1
  ENSSSCP00045013977.1
Reference Protein Sequences
RefSeq Acc Id: XP_020930627   ⟸   XM_021074968
- UniProtKB: A0A8D1H6A4 (UniProtKB/TrEMBL),   F1SJI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000017307   ⟸   ENSSSCT00000017788


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016335 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025075690 UniProtKB/TrEMBL
  ENSSSCG00035021760 UniProtKB/TrEMBL
  ENSSSCG00045011980 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017788 ENTREZGENE
  ENSSSCT00000017788.4 UniProtKB/TrEMBL
  ENSSSCT00025104510.1 UniProtKB/TrEMBL
  ENSSSCT00035028397.1 UniProtKB/TrEMBL
  ENSSSCT00045020357.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
NCBI Gene ESPNL ENTREZGENE
PANTHER ESPIN UniProtKB/TrEMBL
  ESPIN-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A8D1H6A4 ENTREZGENE, UniProtKB/TrEMBL
  F1SJI0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:96163 ENTREZGENE