RABGGTB (Rab geranylgeranyltransferase subunit beta) - Rat Genome Database

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Gene: RABGGTB (Rab geranylgeranyltransferase subunit beta) Sus scrofa
Analyze
Symbol: RABGGTB (Ensembl: MSH4)
Name: Rab geranylgeranyltransferase subunit beta
RGD ID: 14208255
Description: ENCODES a protein that exhibits isoprenoid binding (ortholog); Rab geranylgeranyltransferase activity (ortholog); small GTPase binding (ortholog); INVOLVED IN protein geranylgeranylation (ortholog); ASSOCIATED WITH genetic disease (ortholog); medium chain acyl-CoA dehydrogenase deficiency (ortholog); FOUND IN Rab-protein geranylgeranyltransferase complex (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: geranylgeranyl transferase type-2 subunit beta; Rab geranylgeranyltransferase beta subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6137,410,691 - 137,534,233 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16137,525,063 - 137,534,132 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26127,497,462 - 127,506,518 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:16978188   PMID:17407547   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RABGGTB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6137,410,691 - 137,534,233 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16137,525,063 - 137,534,132 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26127,497,462 - 127,506,518 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RABGGTB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38175,786,194 - 75,795,090 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl175,786,197 - 75,795,086 (+)EnsemblGRCh38hg38GRCh38
GRCh37176,251,879 - 76,260,775 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36176,024,474 - 76,033,352 (+)NCBINCBI36Build 36hg18NCBI36
Build 34175,963,906 - 75,972,785NCBI
Celera174,491,796 - 74,500,671 (+)NCBICelera
Cytogenetic Map1p31.1NCBI
HuRef174,381,711 - 74,390,606 (+)NCBIHuRef
CHM1_1176,367,172 - 76,376,066 (+)NCBICHM1_1
T2T-CHM13v2.0175,622,856 - 75,631,751 (+)NCBIT2T-CHM13v2.0
Rabggtb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393153,612,926 - 153,618,603 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3153,612,924 - 153,618,646 (-)EnsemblGRCm39 Ensembl
GRCm383153,907,289 - 153,912,966 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3153,907,287 - 153,913,009 (-)EnsemblGRCm38mm10GRCm38
MGSCv373153,570,253 - 153,575,930 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363153,844,841 - 153,849,445 (-)NCBIMGSCv36mm8
Celera3160,370,948 - 160,376,625 (-)NCBICelera
Cytogenetic Map3H3NCBI
cM Map378.76NCBI
Rabggtb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82245,504,586 - 245,510,878 (-)NCBIGRCr8
mRatBN7.22242,844,758 - 242,850,951 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2242,844,762 - 242,851,050 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2250,667,563 - 250,673,774 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02248,561,386 - 248,567,597 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02243,459,951 - 243,466,163 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02260,110,309 - 260,115,574 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2260,110,309 - 260,115,577 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02278,774,376 - 278,779,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42251,852,549 - 251,857,811 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12251,867,151 - 251,872,419 (-)NCBI
Celera2234,777,191 - 234,782,459 (-)NCBICelera
Cytogenetic Map2q45NCBI
Rabggtb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542317,152,380 - 17,162,310 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542317,155,161 - 17,162,237 (-)NCBIChiLan1.0ChiLan1.0
RABGGTB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21151,097,980 - 151,106,943 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11150,258,522 - 150,267,454 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0175,001,443 - 75,010,421 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1176,973,158 - 76,982,083 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl176,973,158 - 76,982,083 (+)Ensemblpanpan1.1panPan2
RABGGTB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1670,824,822 - 70,834,958 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl670,825,188 - 70,835,238 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha673,489,614 - 73,499,688 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0671,417,955 - 71,428,054 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl671,417,956 - 71,428,066 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1670,913,867 - 70,923,901 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0670,859,305 - 70,869,344 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0671,352,611 - 71,362,696 (-)NCBIUU_Cfam_GSD_1.0
Rabggtb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505887,302,500 - 87,310,667 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365712,812,902 - 2,821,019 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RABGGTB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12057,398,684 - 57,407,769 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2057,398,327 - 57,407,712 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603360,102,783 - 60,111,881 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rabggtb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474221,168,290 - 21,175,923 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RABGGTB
204 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 2 3 5 2 20 2 3 3
Low 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: NM_001348295   ⟹   NP_001335224
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16137,525,063 - 137,534,132 (-)NCBI
Sequence:
RefSeq Acc Id: NR_145513
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16137,525,063 - 137,534,132 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093611   ⟹   XP_020949270
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.16137,525,063 - 137,534,109 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001335224   ⟸   NM_001348295
- UniProtKB: A0A4X1ULX5 (UniProtKB/TrEMBL),   F1S9R0 (UniProtKB/TrEMBL),   A0A8D0QVR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020949270   ⟸   XM_021093611
- Peptide Label: isoform X1
- UniProtKB: A0A8D0QVR1 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000003775 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005038406 UniProtKB/TrEMBL
  ENSSSCG00015034407 UniProtKB/TrEMBL
  ENSSSCG00025013820 UniProtKB/TrEMBL
  ENSSSCG00030040110 UniProtKB/TrEMBL
  ENSSSCG00035045797 UniProtKB/TrEMBL
  ENSSSCG00040049387 UniProtKB/TrEMBL
  ENSSSCG00045017051 UniProtKB/TrEMBL
  ENSSSCG00050046848 UniProtKB/TrEMBL
  ENSSSCG00055016182 UniProtKB/TrEMBL
  ENSSSCG00060074333 UniProtKB/TrEMBL
  ENSSSCG00065039169 UniProtKB/TrEMBL
  ENSSSCG00070017640 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004178 ENTREZGENE
  ENSSSCT00000004178.4 UniProtKB/TrEMBL
  ENSSSCT00000041063.3 UniProtKB/TrEMBL
  ENSSSCT00000041771.3 UniProtKB/TrEMBL
  ENSSSCT00000100487.1 UniProtKB/TrEMBL
  ENSSSCT00005062318.1 UniProtKB/TrEMBL
  ENSSSCT00015045772.1 UniProtKB/TrEMBL
  ENSSSCT00015046558.1 UniProtKB/TrEMBL
  ENSSSCT00015046912.1 UniProtKB/TrEMBL
  ENSSSCT00015047150.1 UniProtKB/TrEMBL
  ENSSSCT00025018435.1 UniProtKB/TrEMBL
  ENSSSCT00025018597.1 UniProtKB/TrEMBL
  ENSSSCT00025018702.1 UniProtKB/TrEMBL
  ENSSSCT00025018777.1 UniProtKB/TrEMBL
  ENSSSCT00030055799.1 UniProtKB/TrEMBL
  ENSSSCT00035060882.1 UniProtKB/TrEMBL
  ENSSSCT00040066632.1 UniProtKB/TrEMBL
  ENSSSCT00040066922.1 UniProtKB/TrEMBL
  ENSSSCT00040067302.1 UniProtKB/TrEMBL
  ENSSSCT00045029088.1 UniProtKB/TrEMBL
  ENSSSCT00045029257.1 UniProtKB/TrEMBL
  ENSSSCT00045029451.1 UniProtKB/TrEMBL
  ENSSSCT00045029562.1 UniProtKB/TrEMBL
  ENSSSCT00050063774.1 UniProtKB/TrEMBL
  ENSSSCT00050063801.1 UniProtKB/TrEMBL
  ENSSSCT00050063823.1 UniProtKB/TrEMBL
  ENSSSCT00055031955.1 UniProtKB/TrEMBL
  ENSSSCT00055032165.1 UniProtKB/TrEMBL
  ENSSSCT00055032409.1 UniProtKB/TrEMBL
  ENSSSCT00055032546.1 UniProtKB/TrEMBL
  ENSSSCT00060101673.1 UniProtKB/TrEMBL
  ENSSSCT00060101820.1 UniProtKB/TrEMBL
  ENSSSCT00065053535.1 UniProtKB/TrEMBL
  ENSSSCT00065053552.1 UniProtKB/TrEMBL
  ENSSSCT00070034879.1 UniProtKB/TrEMBL
  ENSSSCT00070034893.1 UniProtKB/TrEMBL
  ENSSSCT00070034912.1 UniProtKB/TrEMBL
  ENSSSCT00070034914.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.20 UniProtKB/TrEMBL
InterPro PFTB_repeat UniProtKB/TrEMBL
  PGGT1B-like UniProtKB/TrEMBL
  Ptb1 UniProtKB/TrEMBL
  Terpenoid_cyclase/PrenylTrfase UniProtKB/TrEMBL
KEGG Report ssc:733698 UniProtKB/TrEMBL
NCBI Gene RABGGTB ENTREZGENE
PANTHER GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA UniProtKB/TrEMBL
  PTHR11774 UniProtKB/TrEMBL
Pfam Prenyltrans UniProtKB/TrEMBL
Superfamily-SCOP SSF48239 UniProtKB/TrEMBL
UniProt A0A287BJ15_PIG UniProtKB/TrEMBL
  A0A4X1UGV4_PIG UniProtKB/TrEMBL
  A0A4X1UL84_PIG UniProtKB/TrEMBL
  A0A4X1ULX5 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UM01_PIG UniProtKB/TrEMBL
  A0A8D0NG95_PIG UniProtKB/TrEMBL
  A0A8D0NLI7_PIG UniProtKB/TrEMBL
  A0A8D0QVR1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0QWS7_PIG UniProtKB/TrEMBL
  A0A8D0UII4_PIG UniProtKB/TrEMBL
  A0A8W4FLD1_PIG UniProtKB/TrEMBL
  F1S9R0 ENTREZGENE, UniProtKB/TrEMBL
  Q19QT1_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287BFL8 UniProtKB/TrEMBL
  A0A287BG92 UniProtKB/TrEMBL