PMEPA1 (prostate transmembrane protein, androgen induced 1) - Rat Genome Database

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Gene: PMEPA1 (prostate transmembrane protein, androgen induced 1) Sus scrofa
Analyze
Symbol: PMEPA1
Name: prostate transmembrane protein, androgen induced 1
RGD ID: 14200671
Description: ENCODES a protein that exhibits protein sequestering activity (inferred); R-SMAD binding (inferred); WW domain binding (inferred); INVOLVED IN negative regulation of signal transduction (inferred); negative regulation of SMAD protein signal transduction (inferred); negative regulation of transforming growth factor beta receptor signaling pathway (inferred); ASSOCIATED WITH breast cancer (ortholog); Experimental Liver Cirrhosis (ortholog); gastric adenocarcinoma (ortholog); FOUND IN early endosome membrane (inferred); endosome (inferred); endosome membrane (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: protein TMEPAI; TMEPAI; transmembrane, prostate androgen induced RNA
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1757,999,287 - 58,054,118 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11757,999,287 - 58,054,329 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21765,159,876 - 65,215,002 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
PMEPA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1757,999,287 - 58,054,118 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11757,999,287 - 58,054,329 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21765,159,876 - 65,215,002 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PMEPA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382057,648,396 - 57,711,472 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2057,648,392 - 57,711,536 (-)EnsemblGRCh38hg38GRCh38
GRCh372056,223,452 - 56,286,528 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362055,656,858 - 55,719,947 (-)NCBINCBI36Build 36hg18NCBI36
Build 342055,656,859 - 55,719,947NCBI
Celera2052,963,835 - 53,026,924 (-)NCBICelera
Cytogenetic Map20q13.31NCBI
HuRef2053,005,433 - 53,067,708 (-)NCBIHuRef
CHM1_12056,124,658 - 56,187,819 (-)NCBICHM1_1
T2T-CHM13v2.02059,426,291 - 59,489,466 (-)NCBIT2T-CHM13v2.0
Pmepa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392173,066,251 - 173,118,329 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2173,066,251 - 173,118,326 (-)EnsemblGRCm39 Ensembl
GRCm382173,224,458 - 173,276,731 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2173,224,458 - 173,276,533 (-)EnsemblGRCm38mm10GRCm38
MGSCv372173,049,966 - 173,102,034 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362172,870,728 - 172,919,472 (-)NCBIMGSCv36mm8
Celera2179,192,066 - 179,202,057 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map295.85NCBI
Pmepa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83182,430,193 - 182,478,649 (-)NCBIGRCr8
mRatBN7.23162,011,884 - 162,060,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3162,012,751 - 162,060,454 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3165,812,187 - 165,818,999 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03174,316,169 - 174,322,997 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03172,052,965 - 172,059,777 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03171,295,630 - 171,342,662 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3171,294,856 - 171,342,646 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03177,360,018 - 177,407,050 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43164,094,654 - 164,140,142 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13164,003,347 - 164,051,086 (-)NCBI
Celera3161,200,373 - 161,207,182 (-)NCBICelera
Cytogenetic Map3q42NCBI
Pmepa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554451,837,062 - 1,847,214 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554451,837,084 - 1,847,214 (+)NCBIChiLan1.0ChiLan1.0
PMEPA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22163,400,110 - 63,462,420 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12063,393,229 - 63,455,537 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02053,989,384 - 54,052,151 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12055,267,089 - 55,329,349 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2055,267,089 - 55,329,347 (-)Ensemblpanpan1.1panPan2
PMEPA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12442,602,608 - 42,637,569 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2442,602,595 - 42,656,209 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2441,846,597 - 41,902,939 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02443,464,654 - 43,520,349 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2443,466,163 - 43,521,173 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12442,571,913 - 42,623,915 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02442,689,091 - 42,745,421 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02443,347,420 - 43,403,784 (-)NCBIUU_Cfam_GSD_1.0
Pmepa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640182,866,513 - 182,877,162 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936530429,045 - 439,866 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936530429,059 - 439,847 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PMEPA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.126,403,358 - 6,465,958 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl26,404,515 - 6,465,982 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605054,461,088 - 54,523,559 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pmepa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474124,051,566 - 24,103,997 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474124,053,947 - 24,103,990 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PMEPA1
1840 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3
Low 10 4 3 5 2 20 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000048672   ⟹   ENSSSCP00000053357
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1757,999,287 - 58,053,674 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000067544   ⟹   ENSSSCP00000069737
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1757,999,287 - 58,054,118 (-)Ensembl
RefSeq Acc Id: NM_001123203   ⟹   NP_001116675
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11757,999,287 - 58,053,674 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005673042   ⟹   XP_005673099
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11757,999,287 - 58,054,329 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013985486   ⟹   XP_013840940
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11757,999,287 - 58,023,490 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005673099   ⟸   XM_005673042
- Peptide Label: isoform X1
- UniProtKB: A0A8D1C8F5 (UniProtKB/TrEMBL),   A0A8D1Q346 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001116675   ⟸   NM_001123203
- UniProtKB: A5GFP6 (UniProtKB/TrEMBL),   A0A4X1USP0 (UniProtKB/TrEMBL),   A0A5G2R6I4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013840940   ⟸   XM_013985486
- Peptide Label: isoform X2
- UniProtKB: A0A8D1Q346 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000053357   ⟸   ENSSSCT00000048672
RefSeq Acc Id: ENSSSCP00000069737   ⟸   ENSSSCT00000067544


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034259 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015004594 UniProtKB/TrEMBL
  ENSSSCG00025009396 UniProtKB/TrEMBL
  ENSSSCG00030040430 UniProtKB/TrEMBL
  ENSSSCG00035057170 UniProtKB/TrEMBL
  ENSSSCG00040010896 UniProtKB/TrEMBL
  ENSSSCG00045005322 UniProtKB/TrEMBL
  ENSSSCG00050078898 UniProtKB/TrEMBL
  ENSSSCG00055008478 UniProtKB/TrEMBL
  ENSSSCG00060049350 UniProtKB/TrEMBL
  ENSSSCG00065037530 UniProtKB/TrEMBL
  ENSSSCG00070018955 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000048672 ENTREZGENE
  ENSSSCT00000048672.1 UniProtKB/TrEMBL
  ENSSSCT00000067544 ENTREZGENE
  ENSSSCT00000067544.1 UniProtKB/TrEMBL
  ENSSSCT00015006167.1 UniProtKB/TrEMBL
  ENSSSCT00015006173.1 UniProtKB/TrEMBL
  ENSSSCT00025012436.1 UniProtKB/TrEMBL
  ENSSSCT00025012447.1 UniProtKB/TrEMBL
  ENSSSCT00030056249.1 UniProtKB/TrEMBL
  ENSSSCT00030056269.1 UniProtKB/TrEMBL
  ENSSSCT00030056285.1 UniProtKB/TrEMBL
  ENSSSCT00030056337.1 UniProtKB/TrEMBL
  ENSSSCT00035076460.1 UniProtKB/TrEMBL
  ENSSSCT00040014221.1 UniProtKB/TrEMBL
  ENSSSCT00040014241.1 UniProtKB/TrEMBL
  ENSSSCT00040014253.1 UniProtKB/TrEMBL
  ENSSSCT00040014274.1 UniProtKB/TrEMBL
  ENSSSCT00045008842.1 UniProtKB/TrEMBL
  ENSSSCT00045008846.1 UniProtKB/TrEMBL
  ENSSSCT00050108858.1 UniProtKB/TrEMBL
  ENSSSCT00050108860.1 UniProtKB/TrEMBL
  ENSSSCT00050108866.1 UniProtKB/TrEMBL
  ENSSSCT00055016594.1 UniProtKB/TrEMBL
  ENSSSCT00055016628.1 UniProtKB/TrEMBL
  ENSSSCT00055016669.1 UniProtKB/TrEMBL
  ENSSSCT00055016695.1 UniProtKB/TrEMBL
  ENSSSCT00060067019.1 UniProtKB/TrEMBL
  ENSSSCT00060067029.1 UniProtKB/TrEMBL
  ENSSSCT00060067048.1 UniProtKB/TrEMBL
  ENSSSCT00065051244.1 UniProtKB/TrEMBL
  ENSSSCT00065051246.1 UniProtKB/TrEMBL
  ENSSSCT00070037406.1 UniProtKB/TrEMBL
  ENSSSCT00070037426.1 UniProtKB/TrEMBL
  ENSSSCT00070037428.1 UniProtKB/TrEMBL
InterPro TMEPAI/LRAD4 UniProtKB/TrEMBL
KEGG Report ssc:100144523 UniProtKB/TrEMBL
NCBI Gene PMEPA1 ENTREZGENE
PANTHER PTHR16514 UniProtKB/TrEMBL
  PTHR16514:SF5 UniProtKB/TrEMBL
UniProt A0A287BBB7_PIG UniProtKB/TrEMBL
  A0A4X1UMN8_PIG UniProtKB/TrEMBL
  A0A4X1URC7_PIG UniProtKB/TrEMBL
  A0A4X1USP0 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2R6I4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1AMY3_PIG UniProtKB/TrEMBL
  A0A8D1C8F5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1DDT8_PIG UniProtKB/TrEMBL
  A0A8D1Q346 ENTREZGENE, UniProtKB/TrEMBL
  A5GFP6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:95606 ENTREZGENE