RECQL (RecQ like helicase) - Rat Genome Database

Name: RECQL
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: RECQL (RecQ like helicase) Sus scrofa

Analyze

Symbol:

RECQL

Name:

RecQ like helicase

RGD ID:

14200158

Description:

ENCODES a protein that exhibits 3'-5' DNA helicase activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN DNA duplex unwinding (inferred); DNA geometric change (inferred); DNA metabolic process (inferred); ASSOCIATED WITH Breast Cancer, Familial (ortholog); Breast Neoplasms (ortholog); cancer (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); mediator complex (inferred)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ATP-dependent DNA helicase Q1; RecQ protein-like (DNA helicase Q1-like)

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RECQL (RecQ like helicase)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Recql (RecQ protein-like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Recql (RecQ like helicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Recql (RecQ like helicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RECQL (RecQ like helicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RECQL (RecQ like helicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Recql (RecQ like helicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RECQL (RecQ like helicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Recql (RecQ like helicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	51,953,451 - 52,003,740 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	51,953,460 - 51,995,619 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	55,229,615 - 55,272,155 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Breast Cancer, Familial (ISO)

Breast Neoplasms (ISO)

cancer (ISO)

dilated cardiomyopathy 1O (ISO)

Dwarfism (ISO)

epilepsy (ISO)

genetic disease (ISO)

hepatoblastoma (ISO)

hepatocellular carcinoma (ISO)

hereditary breast ovarian cancer syndrome (ISO)

Hereditary Neoplastic Syndromes (ISO)

lung cancer (ISO)

pancreatic cancer (ISO)

RECON PROGEROID SYNDROME (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA duplex unwinding (IEA)

DNA geometric change (IEA)

DNA metabolic process (IEA)

DNA recombination (IEA)

DNA unwinding involved in DNA replication (IEA)

double-strand break repair via homologous recombination (IEA)

replication fork processing (IEA)

Cellular Component

chromosome (IEA)

cytoplasm (IEA)

mediator complex (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

3'-5' DNA helicase activity (IEA)

ATP binding (IEA)

ATP hydrolysis activity (IEA)

DNA helicase activity (IEA)

DNA/DNA annealing activity (IEA)

double-stranded DNA helicase activity (IEA)

four-way junction helicase activity (IEA)

helicase activity (IEA)

hydrolase activity (IEA)

nucleic acid binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:17145712	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RECQL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	51,953,451 - 52,003,740 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	51,953,460 - 51,995,619 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	55,229,615 - 55,272,155 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RECQL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	21,468,910 - 21,501,635 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	21,468,910 - 21,501,669 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	21,621,844 - 21,654,569 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	21,513,965 - 21,545,796 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	21,514,353 - 21,545,796	NCBI
Celera	12	26,777,229 - 26,809,985 (-)	NCBI		Celera
Cytogenetic Map	12	p12.1	NCBI
HuRef	12	21,395,874 - 21,428,641 (-)	NCBI		HuRef
CHM1_1	12	21,587,472 - 21,620,203 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	21,347,594 - 21,380,648 (-)	NCBI		T2T-CHM13v2.0

Recql
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	142,296,068 - 142,332,802 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	142,296,068 - 142,332,813 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	142,350,342 - 142,387,100 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	142,350,342 - 142,387,087 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	142,310,420 - 142,335,607 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	142,319,368 - 142,344,253 (-)	NCBI		MGSCv36	mm8
Celera	6	145,421,861 - 145,447,035 (-)	NCBI		Celera
Cytogenetic Map	6	G2	NCBI
cM Map	6	73.91	NCBI

Recql
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	177,039,351 - 177,063,968 (-)	NCBI		GRCr8
mRatBN7.2	4	175,308,337 - 175,332,965 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	175,304,117 - 175,332,945 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	181,603,185 - 181,627,672 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	177,387,454 - 177,411,941 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	176,008,012 - 176,032,500 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	176,581,892 - 176,606,520 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	176,581,897 - 176,606,382 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	240,795,675 - 240,820,290 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	179,927,255 - 179,951,742 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	180,172,380 - 180,196,866 (-)	NCBI
Celera	4	163,841,046 - 163,865,533 (-)	NCBI		Celera
Cytogenetic Map	4	q44	NCBI

Recql
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	17,113,408 - 17,148,708 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	17,115,443 - 17,148,708 (-)	NCBI	ChiLan1.0	ChiLan1.0

RECQL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	75,300,616 - 75,333,274 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	75,297,014 - 75,329,247 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	64,796,383 - 64,829,165 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	67,400,315 - 67,432,724 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	67,400,315 - 67,432,724 (+)	Ensembl	panpan1.1		panPan2

RECQL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	25,590,326 - 25,636,304 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	25,590,831 - 25,636,685 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	20,715,583 - 20,761,524 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	25,818,962 - 25,865,150 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	25,819,030 - 25,865,148 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	25,611,850 - 25,658,034 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	25,634,863 - 25,681,036 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	20,891,461 - 20,937,671 (-)	NCBI		UU_Cfam_GSD_1.0

Recql
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	87,426,992 - 87,463,355 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936548	5,362,517 - 5,384,338 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936548	5,349,878 - 5,384,603 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RECQL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	21,334,601 - 21,366,943 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	21,331,584 - 21,366,979 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666069	13,777,790 - 13,810,627 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Recql
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	17,185,129 - 17,220,707 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624752	17,183,624 - 17,220,954 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RECQL
1145 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium		2		5				1	3
Low	10	2	3		2	23	2	2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001253707	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021091092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK344949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU457490	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01044615	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000000624 ⟹ ENSSSCP00000000610

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	51,953,184 - 51,995,798 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000059872 ⟹ ENSSSCP00000055660

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	51,953,451 - 52,003,740 (+)	Ensembl

RefSeq Acc Id:

NM_001253707 ⟹ NP_001240636

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	51,953,460 - 51,995,534 (+)	NCBI

Sequence:

show sequence

CCGACCCGGAAGGGCGGATGCTCCCGGCTGGAGAGAAAGGAAAGCCTGGTGGCGGGAAGTTTTT
ATTGGACCGCAGCTGAAAGTGAAAGAAATTTGGCTCTCCAACGTTAGGATGGCATCCATTTCAG
CTCTGAGTGAGGAACTGGATTCTATAACCAATGAGTTACATGCAGTAGACATTCAAATTCAAGG
ACTTTTGGAAAGGCAACAGGAGCTTATTCAGAAAAAAAAAATCCTTGAAAAGAGAATAAAGCAG
TGTTCAGAGGATCCTGATGCTGGGGAAAGCAGTGAATATGATTCTTCACCTGCCTCTTGGAATA
AAGAAGATTTTCCATGGTCTGGTAAAGTTAAAGAAGTTCTGCAAAATATCTTTAAACTGCAGAA
GTTCAGGCCACTTCAGCTGGAAACTATTAATGTAACGATGTCTGGAAAGGAAGTATTTCTCGTT
ATGCCTACAGGAGGTGGGAAGAGCTTATGCTACCAGTTACCAGCGTTATGTTCAGACGGTTTTA
CACTCGTGATTTGCCCATTGATCTCCCTTATGGAAGACCAGTTAATGGTTTTGAAACAATTAGG
AATTTCAGCTACCATGTTAAATGCTTCTAGTTCTAAGGAGCATGTGAAATGGGTCCATGCTGAA
ATGGTAAATAAAAACTCCAAGCTGAAGCTAATTTATGTGACTCCAGAGAAAATTGCAAAAAGCA
AGATGTTTATGTCAAGACTGGAAAAAGCCTATGAAGCAAGGAGATTTACCCGAATTGCTATAGA
TGAAGTTCATTGTTGTAGTCAGTGGGGACATGATTTCAGACCTGATTATAAGGCACTTGGTATT
CTGAAGCGGCAGTTCCCTAACACATCGCTAATTGGACTGACTGCCACTGCGACAAGTCATGTTT
TGAAGGATGCTCAGAAAATATTGTGTGTGGAAAAGTGTTTTACTTTTACAGCTTCTTTTAATCG
ACCTAATCTCTATTATGAGGTTCGGCAGAAGCCCTCAAATACTGAAGATTTTATTGAGGATATT
GTAAAGCTTATCAATGGAAGATACAAGGGGCAATCAGGAATCATATATTGCTTTTCTCAGAAAG
ACTCTGAGCAAGTTACAGTTAGTTTACAGAAATTGGGGATTCATGCGGGTGCTTACCATGCCAA
CATGGAACCAGAAGATAAGACTACAGTTCATAGAAGATGGTCAGCCAATGAAATTCAGGTAGTG
GTGGCAACAGTTGCATTTGGGATGGGAATTGATAAGCCAGATGTGAGGTTTGTTATTCATCATT
CAATGAGTAAATCAATGGAAAATTATTACCAGGAGAGTGGACGTGCAGGTCGAGATGACACGAA
AGCAGACTGTATTTTGTATTATGGCTTTGGAGATATATTCAGGATAAGTTCAATGGTAGTAATG
GAAAATGTGGGACAGCAGAAGCTTTATGAGATGGTATCATATTGCCAAAACATAAGCAAATGTC
GCCGTGTATTGATAGCTCAACATTTTGATGAAGTATGGAGCCCAGAAGAATGTAACAAAATGTG
TGATAATTGCTGTAAAGATACTTCATTTGAGAGAAAGAACATAACAGCATACTGTAGAGATCTA
GTCAAGATCTTGAAGCAGGCAGAGGAACTGAATGAAAAGCTCACTCCACTGAAACTGATCGATT
CTTGGTTGGGAAAGGGAGCAGCCAAACTCAGGGTAGCAGGCATTGCTCCTCCCACACTTCCTCG
TGAAGACCTGGAGAAAATTATTGCCCACTTTCTCATACAGCAGTATCTCAAAGAAGACTACAGT
TTTACGGCTTATGCTACCATCTCCTACTTGAAAATAGGACCTAAAGCTAATCTTTTGAACAATG
AGGCACATGTTATTACTATGCAAGTAAAGAGGCCCACACAGAGCTGTTTCAGGATTGAATCACC
TCAAAGTTGTCATTCTGAAGGAGCTGATAAAAAGAGGGAAGAAAAAAATTCAAGTAACTACCAG
AAGTCTGCACACATGCTTCAGCAATCTAACTGTAATAAGACTATAGGGGCTAAGAAAAGAAAAA
TTGATAATGCATGAGTATTTCTAAATTTTCCAAGAAAATATTTTATGCATGGATACACTATTAG
TTTTGTAGTTAATCAAAAGTTTGACAATTTCATTAATATTTTACACATATGGAACTATATTTTC
AGAATTTATCTCTGAAGTATTCAAGACTTGAGAATTTGAGACCTTGTAAGACTGAAATCTTGGA
TTGTATAAATTTAGTGTGAAACAAGGGAAAAATAAATTACTGTAAAACACTTTAAGGAGTTCCC
TGGTGGCTCAGTAGGTTAAGGATCTGTCATTGTCACCACTGTGGTGCAGGTTTAATCTTTGGCC
TAGGAACATCTGCATGCCTCAGGCACAGCCAAAAAAAGTGGGGGTTATTGAATATAGTCTCCCC
CTCAAAACAAAAAAACCCTTTAAATGTAAAATAGTTAAGAGAATAAGTTCATATAACTCTCTTA
AGCTCTTTATGCCTTGTCATAACTAGCTGTATTTTTTTCTTTTGACATAACTGACTTCCGGTGT
TATTTATACAGAATATTTTACACAGGCTCATCACAGCAAGTAAATGATTTCAGGTTATAATAGC
TGTAGGGAATTCCCTTCATGGCTTGGCGGTTAATGAACCAAACTAGGATCCATGACGATGAAGG
TTCGATCCCTGGCCTCACTCAGTGGGTTAAGGATCCAGGGTTGCCTGTAGGTCACAGACATGGC
TCGGATCCCGAGTTGCTGGGGCTGCGGTGTAGGCCAGTAGCTGTAGCTGATTTGACCCCTAGCC
TGGGAACCTCCATGTGCCCTGAGGGTGGCCCTAAAATAGCGAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_021091092 ⟹ XP_020946751

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	51,956,247 - 51,995,619 (+)	NCBI

Sequence:

show sequence

CTCCAACGTTAGGATGGCATCCATTTCAGCCTGAAGTTGGGAAGAGAAGAAGCACATGCCATGG
GGAATGCCAAAACAAACGACTTCTTGTGAAGATGAATCTTACCAGAATCTGTATTAGTCTCTTA
CTGCCTCAAAGCCTCCAGTTTAGGCAATGCAGAACCTGCCAGCCTGAAGGCTGGTGTACTGCCC
TGTGGAGTTGCACACAACCTGGCTGAGTGTTCAGAGAAGCTGGAGGAGGGGACCAATAGGATCT
GGAGGAGCTGCAGGCCCTGTTATTTCCCCAAGGAGATCTAGCAGCAGCTGGAATTGTGGACCCA
GCTGTTGTCCCATGCCAATGAGGTCAAAATGTGGCTACTGCTTCACTTCTACCTTCTAAATCTC
TGGCTCCCCAGCATGACACAAACGCCCTGCATACAACCAAATACACAACCCCAAAGAGGACAGG
AATTCTCTATTCATCTTTGATATGCTCAGCCCTCTTCTTGCTGAATCACATCCTCCTTAATCTT
CTAACTGAAATCCTGAGATATGAGCTCTGAGTGAGGAACTGGATTCTATAACCAATGAGTTACA
TGCAGTAGACATTCAAATTCAAGAACTTTTGGAAAGGCAACAGGAGCTTATTCAGAAAAAAAAA
ATCCTTGAAAAGAGAATAAAGCAGTGTTCAGAGGATCCTGATGCTGGGGAAAGCAGTGAATATG
ATTCTTCACCTGCCTCTTGGAATAAAGAAGATTTTCCATGGTCTGGTAAAGTTAAAGAAGTTCT
GCAAAATATCTTTAAACTGCAGAAGTTCAGGCCACTTCAGCTGGAAACTATTAATGTAACGATG
TCTGGAAAGGAAGTATTTCTCGTTATGCCTACAGGAGGTGGGAAGAGCTTATGCTACCAGTTAC
CAGCGTTATGTTCAGACGGTTTTACACTCGTGATTTGCCCATTGATCTCCCTTATGGAAGACCA
GTTAATGGTTTTGAAACAATTAGGAATTTCAGCTACCATGTTAAATGCTTCTAGTTCTAAGGAG
CATGTGAAATGGGTCCATGCTGAAATGGTAAATAAAAACTCCAAGCTGAAGCTAATTTATGTGA
CTCCAGAGAAAATTGCAAAAAGCAAGATGTTTATGTCAAGACTGGAAAAAGCCTATGAAGCAAG
GAGATTTACCCGAATTGCTATAGATGAAGTTCATTGTTGTAGTCAGTGGGGACATGATTTCAGA
CCTGATTATAAGGCACTTGGTATTCTGAAGCGGCAGTTCCCTAACACATCGCTAATTGGACTGA
CTGCCACTGCGACAAGTCATGTTTTGAAGGATGCTCAGAAAATATTGTGTGTGGAAAAGTGTTT
TACTTTTACAGCTTCTTTTAATCGACCTAATCTCTATTATGAGGTTCGGCAGAAGCCCTCAAAT
ACTGAAGATTTTATTGAGGATATTGTAAAGCTTATCAATGGAAGATACAAGGGGCAATCAGGAA
TCATATATTGCTTTTCTCAGAAAGACTCTGAGCAAGTTACAGTTAGTTTACAGAAATTGGGGAT
TCATGCGGGTGCTTACCATGCCAACATGGAACCAGAAGATAAGACTACAGTTCATAGAAGATGG
TCAGCCAATGAAATTCAGGTAGTGGTGGCAACAGTTGCATTTGGGATGGGAATTGATAAGCCAG
ATGTGAGGTTTGTTATTCATCATTCAATGAGTAAATCAATGGAAAATTATTACCAGGAGAGTGG
ACGTGCAGGTCGAGATGACACGAAAGCAGACTGTATTTTGTATTATGGCTTTGGAGATATATTC
AGGATAAGTTCAATGGTAGTAATGGAAAATGTGGGACAGCAGAAGCTTTATGAGATGGTATCAT
ATTGCCAAAACATAAGCAAATGTCGCCGTGTATTGATAGCTCAACATTTTGATGAAGTATGGAG
CCCAGAAGAATGTAACAAAATGTGTGATAATTGCTGTAAAGATACTTCATTTGAGAGAAAGAAC
ATAACAGCATACTGTAGAGATCTAGTCAAGATCTTGAAGCAGGCAGAGGAACTGAATGAAAAGC
TCACTCCACTGAAACTGATCGATTCTTGGTTGGGAAAGGGAGCAGCCAAACTCAGGGTAGCAGG
CATTGCTCCTCCCACACTTCCTCGTGAAGACCTGGAGAAAATTATTGCCCACTTTCTCATACAG
CAGTATCTCAAAGAAGACTACAGTTTTACGGCTTATGCTACCATCTCCTACTTGAAAATAGGAC
CTAAAGCTAATCTTTTGAACAATGAGGCACATGTTATTACTATGCAAGTAAAGAGGCCCACACA
GAGCTGTTTCAGGATTGAATCACCTCAAAGTTGTCATTCTGAAGGAGCTGATAAAAAGAGGGAA
GAAAAAAATTCAAGTAACTACCAGAAGTCTGCACACATGCTTCAGCAATCTAACTGTAATAAGA
CTATAGGGGCTAAGAAAAGAAAAATTGATAATGCATGAGTATTTCTAAATTTTCCAAGAAAATA
TTTTATGCATGGATACACTATTAGTTTTGTAGTTAATCAAAAGTTTGACAATTTCATTAATATT
TTACACATATGGAACTATATTTTCAGAATTTATCTCTGAAGTATTCAAGACTTGAGAATTTGAG
ACCTTGTAAGACTGAAATCTTGGATTGTATAAATTTAGTGTGAAACAAGGGAAAAATAAATTAC
TGTAAAACACTTTAAGGAGTTCCCTGGTGGCTCAGTAGGTTAAGGATCTGTCATTGTCACCACT
GTGGTGCAGGTTTAATCTTTGGCCTAGGAACATCTGCATGCCTCAGGCACAGCCAAAAAAAGTG
GGGGTTATTGAATATAGTCTCCCCCTCAAAACAAAAAAACCCTTTAAATGTAAAATAGTTAAGA
GAATAAGTTCATATAACTCTCTTAAGCTCTTTATGCCTTGTCATAACTAGCTGTATTTTTTTCT
TTTGACATAACTGACTTCCGATGTTATTTATACAGAATATTTTACACAGGCTCATCACAGCAAG
TAAATGATTTCAGGTTATAATAGCTGTAGGGAATTCCCTTCATGGCTTGGCGGTTAATGAACCA
AACTAGGATCCATGACGATGAAGGTTCGATCCCTGGCCTCACTCAGTGGGTTAAGGATCCAGGG
TTGCCTGTAGGTCACAGACATGGCTCGGATCCCGAGTTGCTGGGGCTGCGGTGTAGGCCAGTAG
CTGTAGCTGATTTGACCCCTAGCCTGGGAACCTCCATGTGCCCTGAGGGTGGCCCTAAAATAGC
GAAAAAAAAAAAAAAAATAGAATAGTTGTAGACTCCAAATAAAAAAGGATAAAGTATCAATACA
AATAATATCAGCAGGTAAGAACTTGTATTTAAGTAAAA

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Protein Sequences


Protein RefSeqs	NP_001240636	(Get FASTA)	NCBI Sequence Viewer
	XP_020946751	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000055660
	ENSSSCP00000055660.1
	ENSSSCP00035008975.1
	ENSSSCP00055002202.1
	ENSSSCP00065006730.1
	ENSSSCP00070039967.1

RefSeq Acc Id:

NP_001240636 ⟸ NM_001253707

- UniProtKB:

A0A287BGJ9 (UniProtKB/TrEMBL), A0A8D1CNG3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASISALSEELDSITNELHAVDIQIQGLLERQQELIQKKKILEKRIKQCSEDPDAGESSEYDSS
PASWNKEDFPWSGKVKEVLQNIFKLQKFRPLQLETINVTMSGKEVFLVMPTGGGKSLCYQLPAL
CSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSKLKLIYVTPE
KIAKSKMFMSRLEKAYEARRFTRIAIDEVHCCSQWGHDFRPDYKALGILKRQFPNTSLIGLTAT
ATSHVLKDAQKILCVEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIY
CFSQKDSEQVTVSLQKLGIHAGAYHANMEPEDKTTVHRRWSANEIQVVVATVAFGMGIDKPDVR
FVIHHSMSKSMENYYQESGRAGRDDTKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQ
NISKCRRVLIAQHFDEVWSPEECNKMCDNCCKDTSFERKNITAYCRDLVKILKQAEELNEKLTP
LKLIDSWLGKGAAKLRVAGIAPPTLPREDLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKA
NLLNNEAHVITMQVKRPTQSCFRIESPQSCHSEGADKKREEKNSSNYQKSAHMLQQSNCNKTIG
AKKRKIDNA

hide sequence

RefSeq Acc Id:	XP_020946751 ⟸ XM_021091092
- Peptide Label:	isoform X1
- UniProtKB:	A0A287BGJ9 (UniProtKB/TrEMBL), A0A8D1CNG3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSK EHVKWVHAEMVNKNSKLKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAIDEVHCCSQWGHDF RPDYKALGILKRQFPNTSLIGLTATATSHVLKDAQKILCVEKCFTFTASFNRPNLYYEVRQKPS NTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQKLGIHAGAYHANMEPEDKTTVHRR WSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDTKADCILYYGFGDI FRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLIAQHFDEVWSPEECNKMCDNCCKDTSFERK NITAYCRDLVKILKQAEELNEKLTPLKLIDSWLGKGAAKLRVAGIAPPTLPREDLEKIIAHFLI QQYLKEDYSFTAYATISYLKIGPKANLLNNEAHVITMQVKRPTQSCFRIESPQSCHSEGADKKR EEKNSSNYQKSAHMLQQSNCNKTIGAKKRKIDNA hide sequence

RefSeq Acc Id:

ENSSSCP00000000610 ⟸ ENSSSCT00000000624

RefSeq Acc Id:

ENSSSCP00000055660 ⟸ ENSSSCT00000059872

Protein Domains

Helicase ATP-binding Helicase C-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000000580	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00035018582	UniProtKB/TrEMBL
	ENSSSCG00055001601	UniProtKB/TrEMBL
	ENSSSCG00065012360	UniProtKB/TrEMBL
	ENSSSCG00070023740	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000059872	ENTREZGENE
	ENSSSCT00000059872.3	UniProtKB/TrEMBL
	ENSSSCT00035024000.1	UniProtKB/TrEMBL
	ENSSSCT00055002932.1	UniProtKB/TrEMBL
	ENSSSCT00065016485.1	UniProtKB/TrEMBL
	ENSSSCT00070047368.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	DEAD/DEAH_box_helicase_dom	UniProtKB/TrEMBL
	DNA_helicase_ATP-dep_RecQ	UniProtKB/TrEMBL
	Helicase_ATP-bd	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	RecQ_Zn-bd	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	RECQL	ENTREZGENE
PANTHER	ATP-DEPENDENT DNA HELICASE Q1	UniProtKB/TrEMBL
	DNA HELICASE RECQ FAMILY MEMBER	UniProtKB/TrEMBL
Pfam	DEAD	UniProtKB/TrEMBL
	Helicase_C	UniProtKB/TrEMBL
	RecQ_Zn_bind	UniProtKB/TrEMBL
PROSITE	HELICASE_ATP_BIND_1	UniProtKB/TrEMBL
	HELICASE_CTER	UniProtKB/TrEMBL
SMART	DEXDc	UniProtKB/TrEMBL
	HELICc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A287BGJ9	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1VF29_PIG	UniProtKB/TrEMBL
	A0A8D1CNG3	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:92195	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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