ABCC6 (ATP binding cassette subfamily C member 6) - Rat Genome Database

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Gene: ABCC6 (ATP binding cassette subfamily C member 6) Sus scrofa
Analyze
Symbol: ABCC6
Name: ATP binding cassette subfamily C member 6
RGD ID: 14199936
Description: ENCODES a protein that exhibits ABC-type xenobiotic transporter activity (ortholog); ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN inhibition of non-skeletal tissue mineralization (ortholog); inorganic diphosphate transport (ortholog); intracellular phosphate ion homeostasis (ortholog); PARTICIPATES IN multidrug resistance-associated protein mediated transport pathway; ASSOCIATED WITH Animal Disease Models (ortholog); arterial calcification of infancy (ortholog); autistic disorder (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); extracellular region (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; MRP1; multidrug resistance protein 1; multidrug resistance-associated protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl328,261,214 - 28,356,706 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1328,260,935 - 28,356,706 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2328,960,801 - 29,063,405 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:12429346   PMID:19844775   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ABCC6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl328,261,214 - 28,356,706 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1328,260,935 - 28,356,706 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2328,960,801 - 29,063,405 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABCC6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381616,149,565 - 16,223,494 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1616,149,565 - 16,223,522 (-)EnsemblGRCh38hg38GRCh38
GRCh371616,243,422 - 16,317,351 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361616,150,923 - 16,224,838 (-)NCBINCBI36Build 36hg18NCBI36
Build 341616,151,490 - 16,224,815NCBI
Celera1615,923,582 - 15,972,084 (-)NCBICelera
Cytogenetic Map16p13.11NCBI
HuRef1615,637,406 - 15,701,476 (-)NCBIHuRef
HuRef1617,226,645 - 17,228,924 (+)NCBIHuRef
CHM1_11616,327,717 - 16,401,692 (-)NCBICHM1_1
T2T-CHM13v2.01616,154,422 - 16,229,003 (-)NCBIT2T-CHM13v2.0
Abcc6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,625,804 - 45,679,915 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,616,979 - 45,679,726 (-)EnsemblGRCm39 Ensembl
GRCm38745,974,110 - 46,030,491 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,967,555 - 46,030,302 (-)EnsemblGRCm38mm10GRCm38
MGSCv37753,231,750 - 53,285,656 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,844,422 - 45,898,327 (-)NCBIMGSCv36mm8
MGSCv36735,552,479 - 35,606,515 (-)NCBIMGSCv36mm8
Celera741,445,055 - 41,502,729 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.64NCBI
Abcc6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,583,681 - 105,637,895 (-)NCBIGRCr8
mRatBN7.2196,447,224 - 96,501,464 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl196,447,251 - 96,501,464 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,833,395 - 101,887,602 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01110,305,383 - 110,359,590 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,595,749 - 103,649,961 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,954,786 - 102,013,252 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,959,540 - 102,013,243 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01103,042,723 - 103,096,453 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,448,588 - 96,524,655 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,526,698 - 96,602,766 (-)NCBI
Celera190,699,816 - 90,752,348 (-)NCBICelera
Cytogenetic Map1q22NCBI
Abcc6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955442865,238 - 922,221 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955442865,292 - 921,739 (-)NCBIChiLan1.0ChiLan1.0
ABCC6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1627,800,060 - 27,849,170 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl627,798,835 - 27,848,689 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha629,163,710 - 29,212,774 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0627,963,339 - 28,012,220 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl627,963,425 - 28,011,739 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1627,766,376 - 27,815,441 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0627,656,383 - 27,705,374 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0628,061,767 - 28,110,633 (+)NCBIUU_Cfam_GSD_1.0
Abcc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344115,372,021 - 115,412,095 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365013,469,928 - 3,508,577 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCC6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1515,169,725 - 15,243,731 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl515,168,156 - 15,242,811 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606814,739,120 - 14,812,929 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcc6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624782594,511 - 640,180 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624782590,174 - 640,576 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ABCC6
3530 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSSCT00000041197   ⟹   ENSSSCP00000080720
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl328,261,214 - 28,356,706 (+)Ensembl
RefSeq Acc Id: XM_021086559   ⟹   XP_020942218
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1328,260,935 - 28,356,706 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020942218   ⟸   XM_021086559
- UniProtKB: A0A8D0MX88 (UniProtKB/TrEMBL),   A0A8D0R3X9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000080720   ⟸   ENSSSCT00000041197

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007873 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015017013 UniProtKB/TrEMBL
  ENSSSCG00025015961 UniProtKB/TrEMBL
  ENSSSCG00030036136 UniProtKB/TrEMBL
  ENSSSCG00035057520 UniProtKB/TrEMBL
  ENSSSCG00040013277 UniProtKB/TrEMBL
  ENSSSCG00045022771 UniProtKB/TrEMBL
  ENSSSCG00050016480 UniProtKB/TrEMBL
  ENSSSCG00055007304 UniProtKB/TrEMBL
  ENSSSCG00060014618 UniProtKB/TrEMBL
  ENSSSCG00065063338 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000041197 ENTREZGENE
  ENSSSCT00000041197.2 UniProtKB/TrEMBL
  ENSSSCT00015022756.1 UniProtKB/TrEMBL
  ENSSSCT00015023453.1 UniProtKB/TrEMBL
  ENSSSCT00015023565.1 UniProtKB/TrEMBL
  ENSSSCT00015023671.1 UniProtKB/TrEMBL
  ENSSSCT00015023919.1 UniProtKB/TrEMBL
  ENSSSCT00025021531.1 UniProtKB/TrEMBL
  ENSSSCT00025021923.1 UniProtKB/TrEMBL
  ENSSSCT00030050246.1 UniProtKB/TrEMBL
  ENSSSCT00035076929.1 UniProtKB/TrEMBL
  ENSSSCT00035076931.1 UniProtKB/TrEMBL
  ENSSSCT00035076943.1 UniProtKB/TrEMBL
  ENSSSCT00035076950.1 UniProtKB/TrEMBL
  ENSSSCT00040017667.1 UniProtKB/TrEMBL
  ENSSSCT00045038999.1 UniProtKB/TrEMBL
  ENSSSCT00045039370.1 UniProtKB/TrEMBL
  ENSSSCT00045039560.1 UniProtKB/TrEMBL
  ENSSSCT00045039845.1 UniProtKB/TrEMBL
  ENSSSCT00050022511.1 UniProtKB/TrEMBL
  ENSSSCT00055014333.1 UniProtKB/TrEMBL
  ENSSSCT00055014608.1 UniProtKB/TrEMBL
  ENSSSCT00055014697.1 UniProtKB/TrEMBL
  ENSSSCT00055014833.1 UniProtKB/TrEMBL
  ENSSSCT00060019398.1 UniProtKB/TrEMBL
  ENSSSCT00065086875.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/TrEMBL
  ABC_transporter-like_ATP-bd UniProtKB/TrEMBL
  ABC_transporter-like_CS UniProtKB/TrEMBL
  ABC_transporter_C UniProtKB/TrEMBL
  Multidrug-R_assoc UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene ABCC6 ENTREZGENE
PANTHER ATP-BINDING CASSETTE SUB-FAMILY C UniProtKB/TrEMBL
  PTHR24223:SF339 UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PROSITE ABC_TM1F UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90123 UniProtKB/TrEMBL
UniProt A0A8D0MUM7_PIG UniProtKB/TrEMBL
  A0A8D0MUU2_PIG UniProtKB/TrEMBL
  A0A8D0MX88 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MXY2_PIG UniProtKB/TrEMBL
  A0A8D0R3X9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1ABA5_PIG UniProtKB/TrEMBL
  A0A8D1AD16_PIG UniProtKB/TrEMBL
  A0A8D1AI82_PIG UniProtKB/TrEMBL
  A0A8D1AKZ5_PIG UniProtKB/TrEMBL
  A0A8D1I2B0_PIG UniProtKB/TrEMBL
  A0A8D1I4V4_PIG UniProtKB/TrEMBL
  A0A8D1I5Q9_PIG UniProtKB/TrEMBL
  A0A8D1LK52_PIG UniProtKB/TrEMBL
  A0A8D1PTV4_PIG UniProtKB/TrEMBL
  A0A8D1TXE5_PIG UniProtKB/TrEMBL
  A0A8D1TXL3_PIG UniProtKB/TrEMBL
  A0A8D1TXM2_PIG UniProtKB/TrEMBL
  A0A8W4FQN4_PIG UniProtKB/TrEMBL