SCN3B (sodium voltage-gated channel beta subunit 3) - Rat Genome Database

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Gene: SCN3B (sodium voltage-gated channel beta subunit 3) Sus scrofa
Analyze
Symbol: SCN3B
Name: sodium voltage-gated channel beta subunit 3
RGD ID: 14199809
Description: ENCODES a protein that exhibits sodium channel activity (inferred); sodium channel regulator activity (inferred); transmembrane transporter binding (inferred); INVOLVED IN cardiac conduction (ortholog); nervous system development (ortholog); sodium ion transport (ortholog); ASSOCIATED WITH brain edema (ortholog); Brugada syndrome (ortholog); Brugada syndrome 7 (ortholog); FOUND IN membrane (inferred); monoatomic ion channel complex (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium channel subunit beta-3; sodium channel, voltage-gated, type III, beta subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl950,508,880 - 50,583,712 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1950,508,194 - 50,532,432 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2955,796,544 - 55,873,092 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SCN3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl950,508,880 - 50,583,712 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1950,508,194 - 50,532,432 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2955,796,544 - 55,873,092 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCN3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811123,629,188 - 123,654,624 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11123,629,187 - 123,655,244 (-)EnsemblGRCh38hg38GRCh38
GRCh3711123,499,896 - 123,525,332 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611123,005,105 - 123,030,525 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411123,007,132 - 123,030,522NCBI
Celera11120,659,315 - 120,684,712 (-)NCBICelera
Cytogenetic Map11q24.1NCBI
HuRef11119,441,120 - 119,466,515 (-)NCBIHuRef
CHM1_111123,386,094 - 123,411,515 (-)NCBICHM1_1
T2T-CHM13v2.011123,658,164 - 123,683,597 (-)NCBIT2T-CHM13v2.0
Scn3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39940,180,512 - 40,202,914 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl940,180,513 - 40,202,914 (+)EnsemblGRCm39 Ensembl
GRCm38940,269,216 - 40,291,618 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl940,269,217 - 40,291,618 (+)EnsemblGRCm38mm10GRCm38
MGSCv37940,076,801 - 40,099,203 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36940,019,969 - 40,041,678 (+)NCBIMGSCv36mm8
Celera937,506,998 - 37,529,283 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
cM Map921.42NCBI
Scn3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8849,527,529 - 49,550,019 (+)NCBIGRCr8
mRatBN7.2840,630,372 - 40,652,869 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl840,630,455 - 40,652,868 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx846,138,136 - 46,160,555 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0844,416,727 - 44,439,130 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0842,284,327 - 42,306,725 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0844,136,413 - 44,159,011 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl844,136,496 - 44,159,010 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0861,379,751 - 61,402,348 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4843,231,453 - 43,254,066 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1843,240,218 - 43,262,831 (+)NCBI
Celera840,246,442 - 40,268,779 (+)NCBICelera
Cytogenetic Map8q22NCBI
Scn3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541224,388,366 - 24,412,604 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541224,391,764 - 24,412,912 (-)NCBIChiLan1.0ChiLan1.0
SCN3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29124,329,243 - 124,354,342 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111125,433,875 - 125,458,948 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011118,460,860 - 118,486,563 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111122,377,643 - 122,403,065 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11122,377,643 - 122,403,063 (-)Ensemblpanpan1.1panPan2
SCN3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1510,783,235 - 10,808,342 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl510,783,325 - 10,804,242 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha510,839,227 - 10,864,324 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0510,733,388 - 10,758,535 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl510,734,206 - 10,759,133 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1510,837,530 - 10,862,647 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0510,768,079 - 10,793,209 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0510,814,475 - 10,839,652 (+)NCBIUU_Cfam_GSD_1.0
Scn3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947105,161,078 - 105,184,745 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365428,086,702 - 8,105,372 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365428,082,487 - 8,106,154 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCN3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11115,031,634 - 115,057,829 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1115,034,508 - 115,057,787 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604311,051,460 - 11,079,632 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scn3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248801,496,634 - 1,516,684 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248801,496,571 - 1,519,728 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SCN3B
595 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 1 5 14 12 23 3 6 2

Sequence


Ensembl Acc Id: ENSSSCT00000051882   ⟹   ENSSSCP00000058024
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl950,508,198 - 50,524,628 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000098441   ⟹   ENSSSCP00000077500
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl950,508,880 - 50,583,712 (-)Ensembl
RefSeq Acc Id: XM_005667446   ⟹   XP_005667503
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,037 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005667447   ⟹   XP_005667504
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,218 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005667448   ⟹   XP_005667505
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,432 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979501   ⟹   XP_013834955
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979503   ⟹   XP_013834957
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,045 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063040   ⟹   XP_020918699
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,175 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063041   ⟹   XP_020918700
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,037 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063042   ⟹   XP_020918701
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,037 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002335702
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,036 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002335703
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1950,508,194 - 50,532,040 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005667505   ⟸   XM_005667448
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VHU4 (UniProtKB/TrEMBL),   A0A480L113 (UniProtKB/TrEMBL),   A0A8D1W5L9 (UniProtKB/TrEMBL),   A0A8D0Q4B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005667504   ⟸   XM_005667447
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VHU4 (UniProtKB/TrEMBL),   A0A480L113 (UniProtKB/TrEMBL),   A0A8D1W5L9 (UniProtKB/TrEMBL),   A0A8D0Q4B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918699   ⟸   XM_021063040
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VHU4 (UniProtKB/TrEMBL),   A0A480L113 (UniProtKB/TrEMBL),   A0A8D1W5L9 (UniProtKB/TrEMBL),   A0A8D0Q4B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834957   ⟸   XM_013979503
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020918701   ⟸   XM_021063042
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VHU4 (UniProtKB/TrEMBL),   A0A480L113 (UniProtKB/TrEMBL),   A0A8D1W5L9 (UniProtKB/TrEMBL),   A0A8D0Q4B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005667503   ⟸   XM_005667446
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VHU4 (UniProtKB/TrEMBL),   A0A480L113 (UniProtKB/TrEMBL),   A0A8D1W5L9 (UniProtKB/TrEMBL),   A0A8D0Q4B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918700   ⟸   XM_021063041
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VHU4 (UniProtKB/TrEMBL),   A0A480L113 (UniProtKB/TrEMBL),   A0A8D1W5L9 (UniProtKB/TrEMBL),   A0A8D0Q4B5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834955   ⟸   XM_013979501
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VHU4 (UniProtKB/TrEMBL),   A0A480L113 (UniProtKB/TrEMBL),   A0A8D1W5L9 (UniProtKB/TrEMBL),   A0A8D0Q4B5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000058024   ⟸   ENSSSCT00000051882
Ensembl Acc Id: ENSSSCP00000077500   ⟸   ENSSSCT00000098441
Protein Domains
Ig-like   Immunoglobulin V-set


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024299 Ensembl
  ENSSSCG00000053283 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015077042 UniProtKB/TrEMBL
  ENSSSCG00025008060 UniProtKB/TrEMBL
  ENSSSCG00045027018 UniProtKB/TrEMBL
  ENSSSCG00055008614 UniProtKB/TrEMBL
  ENSSSCG00060057903 UniProtKB/TrEMBL
  ENSSSCG00065027109 UniProtKB/TrEMBL
  ENSSSCG00070024570 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000098441 ENTREZGENE
  ENSSSCT00000098441.1 UniProtKB/TrEMBL
  ENSSSCT00015104088.1 UniProtKB/TrEMBL
  ENSSSCT00025010722.1 UniProtKB/TrEMBL
  ENSSSCT00045045981.1 UniProtKB/TrEMBL
  ENSSSCT00045046074.1 UniProtKB/TrEMBL
  ENSSSCT00045046158.1 UniProtKB/TrEMBL
  ENSSSCT00055016876.1 UniProtKB/TrEMBL
  ENSSSCT00060078899.1 UniProtKB/TrEMBL
  ENSSSCT00065036504.1 UniProtKB/TrEMBL
  ENSSSCT00070049036.1 UniProtKB/TrEMBL
  ENSSSCT00070049041.1 UniProtKB/TrEMBL
  ENSSSCT00070049046.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Na_channel_b1/b3 UniProtKB/TrEMBL
KEGG Report ssc:100628130 UniProtKB/TrEMBL
NCBI Gene SCN3B ENTREZGENE
PANTHER PTHR10546 UniProtKB/TrEMBL
  PTHR10546:SF1 UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A480L113 ENTREZGENE
  A0A4X1VHU4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LEP0_PIG UniProtKB/TrEMBL
  A0A8D0Q4B5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1IE11_PIG UniProtKB/TrEMBL
  A0A8D1W5L9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A480L113 UniProtKB/TrEMBL
VGNC ID VGNC:92634 ENTREZGENE