NDUFA4 (NDUFA4 mitochondrial complex associated) - Rat Genome Database

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Gene: NDUFA4 (NDUFA4 mitochondrial complex associated) Sus scrofa
Analyze
Symbol: NDUFA4
Name: NDUFA4 mitochondrial complex associated
RGD ID: 14195433
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); ASSOCIATED WITH genetic disease (ortholog); mitochondrial complex IV deficiency nuclear type 21 (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrial respiratory chain complex I (ortholog); mitochondrial respiratory chain complex IV (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytochrome c oxidase subunit NDUFA4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: NDUFA4  
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl980,636,929 - 80,644,315 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1980,637,005 - 80,644,067 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2988,555,979 - 88,563,046 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
NDUFA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl980,636,929 - 80,644,315 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1980,637,005 - 80,644,067 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2988,555,979 - 88,563,046 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38710,931,943 - 10,940,153 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl710,931,943 - 10,940,153 (-)EnsemblGRCh38hg38GRCh38
GRCh37710,971,570 - 10,979,780 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36710,939,340 - 10,946,338 (-)NCBINCBI36Build 36hg18NCBI36
Build 34710,746,054 - 10,753,053NCBI
Celera710,947,593 - 10,954,592 (-)NCBICelera
Cytogenetic Map7p21.3NCBI
HuRef710,829,724 - 10,838,039 (-)NCBIHuRef
CHM1_1710,972,141 - 10,980,374 (-)NCBICHM1_1
T2T-CHM13v2.0711,062,535 - 11,070,743 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2711,025,124 - 11,033,358 (-)NCBI
Ndufa4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39611,900,371 - 11,907,449 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl611,900,291 - 11,907,496 (-)EnsemblGRCm39 Ensembl
GRCm38611,900,372 - 11,907,450 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl611,900,292 - 11,907,497 (-)EnsemblGRCm38mm10GRCm38
MGSCv37611,850,373 - 11,857,446 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36611,850,373 - 11,857,446 (-)NCBIMGSCv36mm8
Celera611,992,912 - 11,999,985 (-)NCBICelera
Cytogenetic Map6A1NCBI
cM Map65.01NCBI
Ndufa4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8440,968,391 - 40,975,559 (-)NCBIGRCr8
mRatBN7.2440,002,216 - 40,009,384 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl440,002,216 - 40,023,920 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx444,975,238 - 44,982,402 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0440,901,442 - 40,908,606 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0439,304,957 - 39,312,121 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0438,233,680 - 38,240,848 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl438,233,680 - 38,240,848 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0438,070,978 - 38,078,251 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4437,125,782 - 37,133,055 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera435,414,376 - 35,421,532 (-)NCBICelera
Cytogenetic Map4q21NCBI
Ndufa4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543217,502,272 - 17,509,517 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543217,502,272 - 17,509,517 (-)NCBIChiLan1.0ChiLan1.0
NDUFA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2615,760,949 - 15,767,672 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1764,085,666 - 64,092,390 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0711,585,054 - 11,591,775 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1710,932,727 - 10,939,949 (-)NCBIpanpan1.1PanPan1.1panPan2
NDUFA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11425,887,204 - 25,893,746 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1425,468,815 - 25,475,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01425,696,535 - 25,703,079 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11425,864,709 - 25,871,252 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01425,594,037 - 25,600,585 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01425,847,856 - 25,854,404 (-)NCBIUU_Cfam_GSD_1.0
Ndufa4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511839,433,348 - 39,440,232 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936761554,028 - 560,901 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936761554,025 - 560,913 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12147,245,396 - 47,252,145 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2147,245,170 - 47,252,730 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604257,188,514 - 57,195,774 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufa4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248278,366,027 - 8,375,881 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248278,366,597 - 8,373,881 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NDUFA4
186 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High 2 2 2
Medium 10 2 3 5 21 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000028465   ⟹   ENSSSCP00000024241
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl980,636,929 - 80,644,315 (-)Ensembl
RefSeq Acc Id: NM_001097468   ⟹   NP_001090937
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1980,637,005 - 80,644,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013979726   ⟹   XP_013835180
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1980,637,283 - 80,644,067 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001090937 (Get FASTA)   NCBI Sequence Viewer  
  XP_013835180 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABK55629 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000024241.2
Reference Protein Sequences
RefSeq Acc Id: NP_001090937   ⟸   NM_001097468
- UniProtKB: A1XQS3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013835180   ⟸   XM_013979726
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000024241   ⟸   ENSSSCT00000028465


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024313 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000028465.4 UniProtKB/TrEMBL
InterPro B12D UniProtKB/TrEMBL
KEGG Report ssc:100579141 UniProtKB/TrEMBL
NCBI Gene NDUFA4 ENTREZGENE
PANTHER CYTOCHROME C OXIDASE SUBUNIT NDUFA4 UniProtKB/TrEMBL
  PTHR14256 UniProtKB/TrEMBL
Pfam B12D UniProtKB/TrEMBL
UniProt A1XQS3 ENTREZGENE, UniProtKB/TrEMBL
  I3LJI1_PIG UniProtKB/TrEMBL