GGT5 (gamma-glutamyltransferase 5) - Rat Genome Database

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Gene: GGT5 (gamma-glutamyltransferase 5) Sus scrofa
Analyze
Symbol: GGT5
Name: gamma-glutamyltransferase 5
RGD ID: 14192370
Description: ENCODES a protein that exhibits acyltransferase activity (inferred); glutathione hydrolase activity (inferred); hydrolase activity (inferred); INVOLVED IN inflammatory response (ortholog); leukotriene D4 biosynthetic process (ortholog); response to organonitrogen compound (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); Lung Neoplasms (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,640,586 - 49,663,003 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,638,184 - 49,663,007 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,080,650 - 53,104,965 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074  


Genomics

Comparative Map Data
GGT5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,640,586 - 49,663,003 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,638,184 - 49,663,007 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,080,650 - 53,104,965 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GGT5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382224,219,654 - 24,245,142 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2224,219,654 - 24,245,108 (-)EnsemblGRCh38hg38GRCh38
GRCh372224,615,622 - 24,641,110 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,945,622 - 22,971,110 (-)NCBINCBI36Build 36hg18NCBI36
Build 342222,940,192 - 22,965,582NCBI
Celera228,416,020 - 8,441,502 (-)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef227,564,739 - 7,590,237 (-)NCBIHuRef
CHM1_12224,574,371 - 24,599,750 (-)NCBICHM1_1
T2T-CHM13v2.02224,681,268 - 24,706,753 (-)NCBIT2T-CHM13v2.0
Ggt5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391075,425,161 - 75,453,034 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1075,425,174 - 75,453,034 (+)EnsemblGRCm39 Ensembl
GRCm381075,589,327 - 75,617,200 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,589,340 - 75,617,200 (+)EnsemblGRCm38mm10GRCm38
MGSCv371075,052,126 - 75,079,713 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361075,033,097 - 75,060,684 (+)NCBIMGSCv36mm8
Celera1076,634,075 - 76,661,662 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.55NCBI
Ggt5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82013,042,694 - 13,070,960 (-)NCBIGRCr8
mRatBN7.22013,043,255 - 13,071,523 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2013,043,257 - 13,071,450 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2013,749,839 - 13,778,030 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02013,110,786 - 13,138,974 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,583,284 - 13,611,483 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02013,988,444 - 14,001,296 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02016,178,488 - 16,191,069 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01962,302,144 - 62,302,579 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2014,531,284 - 14,557,667 (-)NCBICelera
Cytogenetic Map20p12NCBI
Ggt5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554558,102,499 - 8,125,966 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554558,101,251 - 8,125,597 (+)NCBIChiLan1.0ChiLan1.0
GGT5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22334,004,643 - 34,033,738 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12236,738,366 - 36,767,475 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0225,025,740 - 5,053,074 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12223,110,461 - 23,125,629 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2223,110,780 - 23,125,632 (-)Ensemblpanpan1.1panPan2
GGT5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12628,316,022 - 28,343,928 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2628,317,989 - 28,343,611 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2627,390,911 - 27,419,099 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02629,720,313 - 29,748,512 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12627,804,270 - 27,832,467 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02627,421,067 - 27,449,253 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02628,411,249 - 28,439,354 (+)NCBIUU_Cfam_GSD_1.0
Ggt5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118141,916,314 - 141,959,384 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936619794,889 - 837,736 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936619794,876 - 837,748 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
Ggt5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474710,051,553 - 10,071,983 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474710,050,765 - 10,072,255 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GGT5
362 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 1 5 2 11 2 2 1
Below cutoff 2 12 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011016   ⟹   ENSSSCP00000010728
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1449,640,586 - 49,663,003 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000053617   ⟹   ENSSSCP00000055089
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1449,640,422 - 49,666,293 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000054124   ⟹   ENSSSCP00000059034
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1449,640,422 - 49,666,575 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000071090   ⟹   ENSSSCP00000067082
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1449,654,868 - 49,661,860 (+)Ensembl
RefSeq Acc Id: XM_001929318   ⟹   XP_001929353
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11449,639,005 - 49,663,007 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013983128   ⟹   XP_013838582
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11449,638,184 - 49,663,007 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013983129   ⟹   XP_013838583
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11449,639,003 - 49,663,007 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013983131   ⟹   XP_013838585
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11449,654,650 - 49,663,007 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021074377   ⟹   XP_020930036
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11449,640,976 - 49,663,007 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021074378   ⟹   XP_020930037
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11449,654,180 - 49,663,007 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013838582   ⟸   XM_013983128
- Peptide Label: isoform X1
- UniProtKB: A0A8D1Y038 (UniProtKB/TrEMBL),   F1RLR8 (UniProtKB/TrEMBL),   A0A8D0Y894 (UniProtKB/TrEMBL),   A0A8D0MYB0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013838583   ⟸   XM_013983129
- Peptide Label: isoform X1
- UniProtKB: A0A8D1Y038 (UniProtKB/TrEMBL),   F1RLR8 (UniProtKB/TrEMBL),   A0A8D0Y894 (UniProtKB/TrEMBL),   A0A8D0MYB0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_001929353   ⟸   XM_001929318
- Peptide Label: isoform X3
- UniProtKB: A0A8D0M9T7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020930036   ⟸   XM_021074377
- Peptide Label: isoform X2
- UniProtKB: A0A4X1V1E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020930037   ⟸   XM_021074378
- Peptide Label: isoform X5
- UniProtKB: A0A8D1XXZ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013838585   ⟸   XM_013983131
- Peptide Label: isoform X4
- UniProtKB: A0A4X1V1E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010728   ⟸   ENSSSCT00000011016
RefSeq Acc Id: ENSSSCP00000059034   ⟸   ENSSSCT00000054124
RefSeq Acc Id: ENSSSCP00000067082   ⟸   ENSSSCT00000071090
RefSeq Acc Id: ENSSSCP00000055089   ⟸   ENSSSCT00000053617


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010055 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005045918 UniProtKB/TrEMBL
  ENSSSCG00015020661 UniProtKB/TrEMBL
  ENSSSCG00030074771 UniProtKB/TrEMBL
  ENSSSCG00040059024 UniProtKB/TrEMBL
  ENSSSCG00045014651 UniProtKB/TrEMBL
  ENSSSCG00050022602 UniProtKB/TrEMBL
  ENSSSCG00055010132 UniProtKB/TrEMBL
  ENSSSCG00065021174 UniProtKB/TrEMBL
  ENSSSCG00070021207 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011016 ENTREZGENE
  ENSSSCT00000011016.5 UniProtKB/TrEMBL
  ENSSSCT00000071090.2 UniProtKB/TrEMBL
  ENSSSCT00005074334.1 UniProtKB/TrEMBL
  ENSSSCT00005074336.1 UniProtKB/TrEMBL
  ENSSSCT00015027581.1 UniProtKB/TrEMBL
  ENSSSCT00030105040.1 UniProtKB/TrEMBL
  ENSSSCT00040080171.1 UniProtKB/TrEMBL
  ENSSSCT00045024999.1 UniProtKB/TrEMBL
  ENSSSCT00045025022.1 UniProtKB/TrEMBL
  ENSSSCT00050030525.1 UniProtKB/TrEMBL
  ENSSSCT00055020067.1 UniProtKB/TrEMBL
  ENSSSCT00055020127.1 UniProtKB/TrEMBL
  ENSSSCT00065028195.1 UniProtKB/TrEMBL
  ENSSSCT00065028198.1 UniProtKB/TrEMBL
  ENSSSCT00070042164.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.246.130 UniProtKB/TrEMBL
  3.60.20.40 UniProtKB/TrEMBL
InterPro GGT_lsub_C UniProtKB/TrEMBL
  GGT_peptidase UniProtKB/TrEMBL
  GGT_ssub UniProtKB/TrEMBL
  Ntn_hydrolases_N UniProtKB/TrEMBL
NCBI Gene GGT5 ENTREZGENE
PANTHER GAMMA GLUTAMYL TRANSPEPTIDASE UniProtKB/TrEMBL
  GLUTATHIONE HYDROLASE 5 PROENZYME UniProtKB/TrEMBL
Pfam G_glu_transpept UniProtKB/TrEMBL
PRINTS GGTRANSPTASE UniProtKB/TrEMBL
PROSITE G_GLU_TRANSPEPTIDASE UniProtKB/TrEMBL
Superfamily-SCOP SSF56235 UniProtKB/TrEMBL
UniProt A0A4X1V1E7 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QYR3_PIG UniProtKB/TrEMBL
  A0A8D0M9T7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MYB0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Y894 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1XXZ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Y038 ENTREZGENE, UniProtKB/TrEMBL
  F1RLR8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:88439 ENTREZGENE