ASCL1 (achaete-scute family bHLH transcription factor 1) - Rat Genome Database

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Gene: ASCL1 (achaete-scute family bHLH transcription factor 1) Sus scrofa
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Symbol: ASCL1
Name: achaete-scute family bHLH transcription factor 1
RGD ID: 14190669
Description: ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); chromatin binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN adrenal chromaffin cell differentiation (ortholog); carotid body glomus cell differentiation (ortholog); cell differentiation (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); congenital central hypoventilation syndrome (ortholog); Hyperplasia (ortholog); FOUND IN neuronal cell body (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: achaete-scute homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1581,357,431 - 81,360,335 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal chromaffin cell differentiation  (ISO)
carotid body glomus cell differentiation  (ISO)
cell differentiation  (ISO)
cell maturation  (ISO)
cellular response to magnetism  (ISO)
central nervous system neuron development  (ISO)
cerebral cortex development  (ISO)
cerebral cortex GABAergic interneuron differentiation  (ISO)
commitment of neuronal cell to specific neuron type in forebrain  (ISO)
forebrain neuron differentiation  (ISO)
generation of neurons  (ISO)
glial cell differentiation  (ISO)
heart development  (ISO)
lung neuroendocrine cell differentiation  (ISO)
musculoskeletal movement, spinal reflex action  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of neuron differentiation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
nervous system development  (ISO)
neuroblast fate determination  (ISO)
neuroblast proliferation  (ISO)
neurogenesis  (ISO)
neuron development  (ISO)
neuron differentiation  (ISO)
neuron fate commitment  (ISO)
neuron fate specification  (ISO)
neuron migration  (ISO)
noradrenergic neuron development  (ISO)
noradrenergic neuron fate commitment  (ISO)
Notch signaling pathway  (ISO)
olfactory pit development  (ISO)
oligodendrocyte cell fate commitment  (ISO)
oligodendrocyte development  (ISO)
oligodendrocyte differentiation  (ISO)
pattern specification process  (ISO)
positive regulation of cell cycle  (ISO)
positive regulation of neural precursor cell proliferation  (ISO)
positive regulation of neurogenesis  (ISO)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of Notch signaling pathway  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
regulation of cell population proliferation  (ISO)
regulation of epithelial cell differentiation  (ISO)
regulation of gene expression  (ISO)
regulation of mitotic cell cycle  (ISO)
regulation of neurogenesis  (ISO)
regulation of Notch signaling pathway  (ISO)
regulation of timing of subpallium neuron differentiation  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
response to epidermal growth factor  (ISO)
response to folic acid  (ISO)
response to lithium ion  (ISO)
response to retinoic acid  (ISO)
spinal cord association neuron differentiation  (ISO)
spinal cord oligodendrocyte cell differentiation  (ISO)
spinal cord oligodendrocyte cell fate specification  (ISO)
stomach neuroendocrine cell differentiation  (ISO)
subpallium neuron fate commitment  (ISO)
sympathetic ganglion development  (ISO)
ventral spinal cord interneuron fate commitment  (ISO)
vestibular nucleus development  (ISO)

Cellular Component

References

Genomics

Comparative Map Data
ASCL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1581,357,431 - 81,360,335 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ASCL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12102,957,674 - 102,960,513 (+)EnsemblGRCh38hg38GRCh38
GRCh3812102,957,674 - 102,960,513 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712103,351,452 - 103,354,291 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612101,875,594 - 101,878,421 (+)NCBINCBI36hg18NCBI36
Build 3412101,853,930 - 101,856,754NCBI
Celera12103,015,725 - 103,018,566 (+)NCBI
Cytogenetic Map12q23.2NCBI
HuRef12100,410,703 - 100,413,544 (+)NCBIHuRef
CHM1_112103,318,246 - 103,321,086 (+)NCBICHM1_1
Ascl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391087,326,681 - 87,329,522 (-)NCBIGRCm39mm39
GRCm39 Ensembl1087,326,681 - 87,329,522 (-)Ensembl
GRCm381087,490,819 - 87,493,660 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1087,490,819 - 87,493,660 (-)EnsemblGRCm38mm10GRCm38
MGSCv371086,953,786 - 86,956,405 (-)NCBIGRCm37mm9NCBIm37
MGSCv361086,920,621 - 86,922,980 (-)NCBImm8
Celera1089,464,389 - 89,467,010 (-)NCBICelera
Cytogenetic Map10C1NCBI
Ascl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2721,904,153 - 21,906,003 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl721,903,126 - 21,905,993 (-)Ensembl
Rnor_6.0728,038,662 - 28,040,504 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl728,038,662 - 28,040,510 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0728,152,425 - 28,154,275 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4724,145,578 - 24,168,494 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1724,165,848 - 24,167,679 (-)NCBI
Celera719,079,344 - 19,081,186 (-)NCBICelera
Cytogenetic Map7q13NCBI
Ascl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540537,941,243 - 37,943,641 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540537,941,243 - 37,943,641 (+)NCBIChiLan1.0ChiLan1.0
ASCL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112103,931,707 - 103,934,554 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12103,932,302 - 103,932,999 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012100,536,895 - 100,539,737 (+)NCBIMhudiblu_PPA_v0panPan3
ASCL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11541,694,021 - 41,696,933 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1541,694,269 - 41,695,391 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1542,062,179 - 42,065,075 (+)NCBI
ROS_Cfam_1.01542,349,900 - 42,352,808 (+)NCBI
UMICH_Zoey_3.11541,619,328 - 41,622,224 (+)NCBI
UNSW_CanFamBas_1.01541,717,251 - 41,720,147 (+)NCBI
UU_Cfam_GSD_1.01541,986,771 - 41,989,679 (+)NCBI
Ascl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494518,304,396 - 18,306,779 (-)NCBI
SpeTri2.0NW_00493649211,315,929 - 11,317,166 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASCL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11198,182,213 - 98,185,057 (+)NCBI
ChlSab1.1 Ensembl1198,182,787 - 98,183,506 (+)Ensembl
Vero_WHO_p1.0NW_023666037146,827,687 - 146,830,550 (-)NCBI
Ascl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247505,487,046 - 5,489,399 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021092654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_021092654   ⟹   XP_020948313
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1581,357,431 - 81,360,335 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020948313 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020948313   ⟸   XM_021092654
- Sequence:


Additional Information

Database Acc Id Source(s)
NCBI Gene ASCL1 ENTREZGENE