CENPT (centromere protein T) - Rat Genome Database

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Gene: CENPT (centromere protein T) Sus scrofa
Analyze
Symbol: CENPT
Name: centromere protein T
RGD ID: 14189793
Description: ENCODES a protein that exhibits DNA binding (inferred); protein heterodimerization activity (inferred); INVOLVED IN cell division (inferred); chromosome organization (inferred); chromosome segregation (inferred); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); genetic disease (ortholog); inherited metabolic disorder (ortholog); FOUND IN inner kinetochore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,450,569 - 28,456,229 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1628,450,568 - 28,456,620 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2625,668,564 - 25,682,398 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CENPT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,450,569 - 28,456,229 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1628,450,568 - 28,456,620 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2625,668,564 - 25,682,398 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CENPT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,828,157 - 67,847,693 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,828,157 - 67,847,811 (-)EnsemblGRCh38hg38GRCh38
GRCh371667,862,060 - 67,881,596 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,419,561 - 66,438,862 (-)NCBINCBI36Build 36hg18NCBI36
Celera1652,370,476 - 52,389,773 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,735,010 - 53,754,438 (-)NCBIHuRef
CHM1_11669,270,266 - 69,289,543 (-)NCBICHM1_1
T2T-CHM13v2.01673,623,939 - 73,643,467 (-)NCBIT2T-CHM13v2.0
Cenpt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,571,297 - 106,581,678 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,571,305 - 106,579,910 (-)EnsemblGRCm39 Ensembl
GRCm388105,844,669 - 105,855,086 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,844,673 - 105,853,278 (-)EnsemblGRCm38mm10GRCm38
MGSCv378108,368,578 - 108,375,908 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368108,733,807 - 108,741,137 (-)NCBIMGSCv36mm8
Celera8110,072,453 - 110,079,784 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.05NCBI
Cenpt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,644,548 - 50,651,048 (-)NCBIGRCr8
mRatBN7.21933,734,684 - 33,741,159 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,734,685 - 33,741,142 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,550,226 - 40,556,666 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,203,547 - 41,209,987 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,501,848 - 43,508,316 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,813,284 - 37,819,782 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,812,751 - 37,819,789 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,680,055 - 48,686,554 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,680,014 - 35,686,455 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,684,895 - 35,691,336 (-)NCBI
Celera1933,162,346 - 33,168,786 (-)NCBICelera
Cytogenetic Map19q12NCBI
Cenpt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554848,862,206 - 8,867,771 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554848,862,221 - 8,867,881 (+)NCBIChiLan1.0ChiLan1.0
CENPT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,355,183 - 77,374,790 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11683,266,631 - 83,285,249 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01648,169,892 - 48,177,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11667,557,661 - 67,565,267 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,557,661 - 67,564,735 (-)Ensemblpanpan1.1panPan2
CENPT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,641,261 - 81,647,047 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,641,426 - 81,647,039 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,631,054 - 81,636,750 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,076,463 - 82,082,161 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,076,538 - 82,082,153 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1581,902,886 - 81,908,582 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,584,471 - 81,590,166 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,226,961 - 82,232,656 (+)NCBIUU_Cfam_GSD_1.0
Cenpt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,384,099 - 41,390,488 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647518,198,733 - 18,203,963 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647518,198,725 - 18,204,257 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,604,893 - 59,611,140 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl559,605,149 - 59,614,206 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604722,331,590 - 22,338,090 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cenpt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,532,732 - 18,538,326 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474618,530,574 - 18,538,437 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CENPT
78 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 7 2 3 5 23 1 3 3
Below cutoff 3 1 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000003066   ⟹   ENSSSCP00000002987
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl628,446,687 - 28,456,230 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000062657   ⟹   ENSSSCP00000051845
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl628,450,569 - 28,456,202 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000071960   ⟹   ENSSSCP00000064985
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl628,454,587 - 28,456,229 (-)Ensembl
RefSeq Acc Id: XM_021094110   ⟹   XP_020949769
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1628,450,568 - 28,456,605 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002344575
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1628,450,573 - 28,456,620 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020949769   ⟸   XM_021094110
- UniProtKB: A0A4X1UG26 (UniProtKB/TrEMBL),   A0A287B6Z0 (UniProtKB/TrEMBL),   A0A8D0IHJ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000002987   ⟸   ENSSSCT00000003066
RefSeq Acc Id: ENSSSCP00000051845   ⟸   ENSSSCT00000062657
RefSeq Acc Id: ENSSSCP00000064985   ⟸   ENSSSCT00000071960
Protein Domains
CENP-T/Histone H4 histone fold   Centromere kinetochore component CENP-T N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002768 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005009270 UniProtKB/TrEMBL
  ENSSSCG00025070800 UniProtKB/TrEMBL
  ENSSSCG00030001463 UniProtKB/TrEMBL
  ENSSSCG00035035673 UniProtKB/TrEMBL
  ENSSSCG00045027078 UniProtKB/TrEMBL
  ENSSSCG00055009549 UniProtKB/TrEMBL
  ENSSSCG00060078290 UniProtKB/TrEMBL
  ENSSSCG00065032664 UniProtKB/TrEMBL
  ENSSSCG00070017086 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000062657 ENTREZGENE
  ENSSSCT00000062657.3 UniProtKB/TrEMBL
  ENSSSCT00000071960.2 UniProtKB/TrEMBL
  ENSSSCT00005014707.1 UniProtKB/TrEMBL
  ENSSSCT00005014791.1 UniProtKB/TrEMBL
  ENSSSCT00025097332.1 UniProtKB/TrEMBL
  ENSSSCT00030001947.1 UniProtKB/TrEMBL
  ENSSSCT00035047298.1 UniProtKB/TrEMBL
  ENSSSCT00045046312.1 UniProtKB/TrEMBL
  ENSSSCT00055018704.1 UniProtKB/TrEMBL
  ENSSSCT00060108096.1 UniProtKB/TrEMBL
  ENSSSCT00065044330.1 UniProtKB/TrEMBL
  ENSSSCT00070033685.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
InterPro CENP-T UniProtKB/TrEMBL
  CENP-T/H4_C UniProtKB/TrEMBL
  CENP-T_N UniProtKB/TrEMBL
  Histone-fold UniProtKB/TrEMBL
NCBI Gene CENPT ENTREZGENE
PANTHER CENTROMERE PROTEIN T UniProtKB/TrEMBL
  PTHR46904 UniProtKB/TrEMBL
Pfam CENP-T_C UniProtKB/TrEMBL
  CENP-T_N UniProtKB/TrEMBL
Superfamily-SCOP SSF47113 UniProtKB/TrEMBL
UniProt A0A287B6Z0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UG26 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IHJ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0ZIY8_PIG UniProtKB/TrEMBL
UniProt Secondary A0A5G2QLR4 UniProtKB/TrEMBL
VGNC ID VGNC:86556 ENTREZGENE