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Gene: CASP8 (caspase 8) Sus scrofa
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Symbol: CASP8
Name: caspase 8
Description: ENCODES a protein that exhibits identical protein binding (inferred); scaffold protein binding (inferred); ubiquitin protein ligase binding (inferred); INVOLVED IN activation of cysteine-type endopeptidase activity (inferred); cellular response to mechanical stimulus (inferred); execution phase of apoptosis (inferred); PARTICIPATES IN Alzheimer's disease pathway; apoptotic cell death pathway; ceramide signaling pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); Acute Lung Injury (ortholog); adenocarcinoma (ortholog); FOUND IN CD95 death-inducing signaling complex (inferred); nucleoplasm (inferred); ripoptosome (inferred); INTERACTS WITH 3-methyladenine; ATP; cilastatin
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: caspase 8, apoptosis-related cysteine peptidase; caspase-8
Orthologs:
Homo sapiens (human) : CASP8 (caspase 8)  HGNC  Alliance
Mus musculus (house mouse) : Casp8 (caspase 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Casp8 (caspase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp8 (caspase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP8 (caspase 8)
Canis lupus familiaris (dog) : CASP8 (caspase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp8 (caspase 8)
Chlorocebus sabaeus (African green monkey) : CASP8 (caspase 8)
Heterocephalus glaber (naked mole-rat) : Casp8 (caspase 8)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15104,923,953 - 104,948,470 (+)Ensembl
Sscrofa11.115104,923,659 - 104,948,470 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215116,337,232 - 116,340,859 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on CASP8
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 14187349
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.