SGPL1 (sphingosine-1-phosphate lyase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: SGPL1 (sphingosine-1-phosphate lyase 1) Sus scrofa
Analyze
Symbol: SGPL1
Name: sphingosine-1-phosphate lyase 1
RGD ID: 14181399
Description: ENCODES a protein that exhibits carbon-carbon lyase activity (inferred); pyridoxal phosphate binding (inferred); sphinganine-1-phosphate aldolase activity (inferred); INVOLVED IN androgen metabolic process (ortholog); estrogen metabolic process (ortholog); face morphogenesis (ortholog); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH nephrotic syndrome type 14 (ortholog); FOUND IN endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1473,723,800 - 73,781,830 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11473,696,902 - 73,781,830 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21479,572,301 - 79,628,480 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
SGPL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1473,723,800 - 73,781,830 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11473,696,902 - 73,781,830 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21479,572,301 - 79,628,480 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SGPL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1070,815,948 - 70,881,184 (+)EnsemblGRCh38hg38GRCh38
GRCh381070,815,920 - 70,881,184 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371072,575,704 - 72,640,941 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361072,245,722 - 72,309,873 (+)NCBINCBI36hg18NCBI36
Build 341072,245,721 - 72,309,871NCBI
Celera1065,857,672 - 65,923,231 (+)NCBI
Cytogenetic Map10q22.1NCBI
HuRef1066,569,390 - 66,634,948 (+)NCBIHuRef
CHM1_11072,858,499 - 72,923,730 (+)NCBICHM1_1
Sgpl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391060,934,421 - 60,983,463 (-)NCBIGRCm39mm39
GRCm39 Ensembl1060,934,421 - 60,983,482 (-)Ensembl
GRCm381061,098,642 - 61,147,684 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1061,098,642 - 61,147,703 (-)EnsemblGRCm38mm10GRCm38
MGSCv371060,561,390 - 60,610,413 (-)NCBIGRCm37mm9NCBIm37
MGSCv361060,493,999 - 60,542,956 (-)NCBImm8
Celera1062,199,269 - 62,248,215 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.14NCBI
Sgpl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22029,047,793 - 29,094,209 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2029,047,796 - 29,094,084 (-)Ensembl
Rnor_6.02030,699,936 - 30,769,178 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2030,699,872 - 30,749,940 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02032,497,280 - 32,543,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42028,459,734 - 28,505,017 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12028,473,533 - 28,518,817 (-)NCBI
Celera2030,483,317 - 30,527,561 (-)NCBICelera
Cytogenetic Map20q11NCBI
Sgpl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543720,488,330 - 20,547,171 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543720,489,641 - 20,547,105 (-)NCBIChiLan1.0ChiLan1.0
SGPL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11069,812,082 - 69,876,444 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1069,812,092 - 69,876,438 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01067,286,349 - 67,351,574 (+)NCBIMhudiblu_PPA_v0panPan3
SGPL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1421,666,264 - 21,717,476 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl421,660,939 - 21,715,155 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha421,795,341 - 21,851,669 (+)NCBI
ROS_Cfam_1.0421,939,185 - 21,995,525 (+)NCBI
UMICH_Zoey_3.1421,834,799 - 21,891,148 (+)NCBI
UNSW_CanFamBas_1.0422,040,063 - 22,096,345 (+)NCBI
UU_Cfam_GSD_1.0422,392,266 - 22,448,632 (+)NCBI
Sgpl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721359,357,640 - 59,407,321 (-)NCBI
SpeTri2.0NW_0049365217,850,370 - 7,899,998 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGPL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1960,425,703 - 60,487,196 (-)NCBI
ChlSab1.1 Ensembl960,424,305 - 60,487,146 (-)Ensembl
Vero_WHO_p1.0NW_02366604821,148,927 - 21,211,740 (-)NCBI
Sgpl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247544,844,472 - 4,889,006 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 2 3 5 6 3 3
Low 2 2 2 17 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011246   ⟹   ENSSSCP00000010954
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1473,723,800 - 73,779,717 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000042658   ⟹   ENSSSCP00000055280
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1473,724,390 - 73,781,662 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000045496   ⟹   ENSSSCP00000054654
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1473,724,166 - 73,780,364 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000047829   ⟹   ENSSSCP00000047377
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1473,724,220 - 73,781,800 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000056069   ⟹   ENSSSCP00000046783
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1473,724,100 - 73,780,359 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000059184   ⟹   ENSSSCP00000035877
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1473,724,169 - 73,781,830 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000064467   ⟹   ENSSSCP00000048727
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1473,724,034 - 73,781,830 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000072375   ⟹   ENSSSCP00000073520
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1473,754,990 - 73,781,830 (+)Ensembl
RefSeq Acc Id: XM_003133063   ⟹   XP_003133111
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,724,006 - 73,780,368 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005657406   ⟹   XP_005657463
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,724,088 - 73,780,368 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005657407   ⟹   XP_005657464
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,724,397 - 73,780,368 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005657408   ⟹   XP_005657465
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,724,397 - 73,780,368 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005657409   ⟹   XP_005657466
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,724,166 - 73,780,368 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005657410   ⟹   XP_005657467
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,724,089 - 73,780,368 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005657411   ⟹   XP_005657468
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,696,902 - 73,780,368 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021073925   ⟹   XP_020929584
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,724,504 - 73,780,368 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002338876
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11473,724,061 - 73,781,830 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005657468   ⟸   XM_005657411
- Peptide Label: isoform X4
- UniProtKB: K9IVV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003133111   ⟸   XM_003133063
- Peptide Label: isoform X4
- UniProtKB: K9IVV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005657463   ⟸   XM_005657406
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005657467   ⟸   XM_005657410
- Peptide Label: isoform X4
- UniProtKB: K9IVV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005657466   ⟸   XM_005657409
- Peptide Label: isoform X4
- UniProtKB: K9IVV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005657464   ⟸   XM_005657407
- Peptide Label: isoform X2
- UniProtKB: F1SUB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005657465   ⟸   XM_005657408
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020929584   ⟸   XM_021073925
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSSSCP00000048727   ⟸   ENSSSCT00000064467
RefSeq Acc Id: ENSSSCP00000035877   ⟸   ENSSSCT00000059184
RefSeq Acc Id: ENSSSCP00000010954   ⟸   ENSSSCT00000011246
RefSeq Acc Id: ENSSSCP00000054654   ⟸   ENSSSCT00000045496
RefSeq Acc Id: ENSSSCP00000055280   ⟸   ENSSSCT00000042658
RefSeq Acc Id: ENSSSCP00000046783   ⟸   ENSSSCT00000056069
RefSeq Acc Id: ENSSSCP00000073520   ⟸   ENSSSCT00000072375
RefSeq Acc Id: ENSSSCP00000047377   ⟸   ENSSSCT00000047829


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010274 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000010954 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000035877 UniProtKB/TrEMBL
  ENSSSCP00000046783 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000047377 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000048727 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000054654 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000055280 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000073520 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011246 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000042658 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000045496 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000047829 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000056069 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000059184 UniProtKB/TrEMBL
  ENSSSCT00000064467 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000072375 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/TrEMBL
InterPro PyrdxlP-dep_de-COase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_dom1 UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/TrEMBL
KEGG Report ssc:100525187 UniProtKB/TrEMBL
NCBI Gene SGPL1 ENTREZGENE
Pfam Pyridoxal_deC UniProtKB/TrEMBL
Superfamily-SCOP SSF53383 UniProtKB/TrEMBL
UniProt A0A286ZW55_PIG UniProtKB/TrEMBL
  A0A287ARS0_PIG UniProtKB/TrEMBL
  A0A287ATW8_PIG UniProtKB/TrEMBL
  A0A287AX55_PIG UniProtKB/TrEMBL
  A0A287BEZ7_PIG UniProtKB/TrEMBL
  A0A287BGV0_PIG UniProtKB/TrEMBL
  A0A5G2RB20_PIG UniProtKB/TrEMBL
  F1SUB2 ENTREZGENE, UniProtKB/TrEMBL
  K9IVV1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92797 ENTREZGENE