CSF2RB (colony stimulating factor 2 receptor subunit beta) - Rat Genome Database

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Gene: CSF2RB (colony stimulating factor 2 receptor subunit beta) Sus scrofa
Analyze
Symbol: CSF2RB
Name: colony stimulating factor 2 receptor subunit beta
RGD ID: 14175092
Description: ENCODES a protein that exhibits coreceptor activity (inferred); cytokine receptor activity (inferred); INVOLVED IN response to lipopolysaccharide (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; interleukin-3 signaling pathway; interleukin-5 signaling pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); asthma (ortholog); autosomal recessive chronic granulomatous disease 3 (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: colony stimulating factor 2 receptor beta common subunit; cytokine receptor common subunit beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,816,376 - 10,840,618 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,816,366 - 10,840,613 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.258,415,807 - 8,439,906 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CSF2RB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,816,376 - 10,840,618 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,816,366 - 10,840,613 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.258,415,807 - 8,439,906 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CSF2RB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382236,913,628 - 36,940,439 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2236,913,628 - 36,940,439 (+)EnsemblGRCh38hg38GRCh38
GRCh372237,309,670 - 37,336,481 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362235,648,168 - 35,664,764 (+)NCBINCBI36Build 36hg18NCBI36
Build 342235,642,721 - 35,659,318NCBI
Celera2221,111,014 - 21,137,820 (+)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2220,271,284 - 20,300,485 (+)NCBIHuRef
CHM1_12237,269,205 - 37,296,007 (+)NCBICHM1_1
T2T-CHM13v2.02237,372,586 - 37,399,383 (+)NCBIT2T-CHM13v2.0
Csf2rb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,166,707 - 78,189,921 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,166,707 - 78,189,921 (-)EnsemblGRCm39 Ensembl
GRCm381578,282,507 - 78,305,721 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,282,507 - 78,305,721 (-)EnsemblGRCm38mm10GRCm38
MGSCv371578,112,940 - 78,136,033 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,109,765 - 78,132,858 (-)NCBIMGSCv36mm8
Celera1579,743,456 - 79,766,549 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.22NCBI
Csf2rb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,756,950 - 111,782,089 (+)NCBIGRCr8
mRatBN7.27109,876,919 - 109,901,589 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7109,886,425 - 109,904,157 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7111,626,685 - 111,649,953 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07113,850,226 - 113,873,488 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07113,818,844 - 113,842,074 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07119,554,383 - 119,568,248 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7119,554,354 - 119,568,776 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07119,544,873 - 119,558,539 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,227,239 - 116,271,993 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,271,510 - 116,306,223 (+)NCBI
Celera7106,216,478 - 106,238,726 (+)NCBICelera
Cytogenetic Map7q34NCBI
Csf2rb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,449,111 - 23,463,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,442,417 - 23,465,093 (+)NCBIChiLan1.0ChiLan1.0
CSF2RB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22346,770,999 - 46,797,941 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12249,462,363 - 49,489,315 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02217,831,313 - 17,858,272 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12235,666,729 - 35,693,708 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2235,666,734 - 35,693,701 (+)Ensemblpanpan1.1panPan2
CSF2RB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,541,645 - 27,566,907 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,541,647 - 27,567,278 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1027,496,146 - 27,521,244 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01028,333,755 - 28,358,851 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1028,333,760 - 28,358,984 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11028,055,276 - 28,080,375 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01028,363,777 - 28,388,879 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,542,588 - 28,567,688 (-)NCBIUU_Cfam_GSD_1.0
Csf2rb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,919,175 - 10,950,319 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364923,929,589 - 3,974,070 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CSF2RB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11919,614,719 - 19,642,546 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1919,624,234 - 19,640,617 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045106,220,245 - 106,247,737 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in CSF2RB
1146 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000000142   ⟹   ENSSSCP00000000140
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl510,816,376 - 10,840,363 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000085649   ⟹   ENSSSCP00000063095
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl510,817,686 - 10,840,618 (-)Ensembl
RefSeq Acc Id: XM_001924779   ⟹   XP_001924814
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1510,816,366 - 10,840,613 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001924814 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000000140
  ENSSSCP00000000140.5
  ENSSSCP00000063095.1
  ENSSSCP00045036379.1
  ENSSSCP00045036483.1
  ENSSSCP00055048617.1
  ENSSSCP00055048622.1
GenBank Protein JAG69616 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_001924814   ⟸   XM_001924779
- UniProtKB: A0A0B8RVZ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000063095   ⟸   ENSSSCT00000085649
Ensembl Acc Id: ENSSSCP00000000140   ⟸   ENSSSCT00000000142
Protein Domains
Fibronectin type-III


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000136 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00045030650 UniProtKB/TrEMBL
  ENSSSCG00055030477 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000142 ENTREZGENE
  ENSSSCT00000000142.5 UniProtKB/TrEMBL
  ENSSSCT00000085649.2 UniProtKB/TrEMBL
  ENSSSCT00045052303.1 UniProtKB/TrEMBL
  ENSSSCT00045052466.1 UniProtKB/TrEMBL
  ENSSSCT00055060677.1 UniProtKB/TrEMBL
  ENSSSCT00055060682.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Hempt_rcpt_S_F1_CS UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  IL3RB_N UniProtKB/TrEMBL
  TypeI_recpt_CBD UniProtKB/TrEMBL
NCBI Gene CSF2RB ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  CYTOKINE RECEPTOR COMMON SUBUNIT BETA UniProtKB/TrEMBL
Pfam IL3Rb_N UniProtKB/TrEMBL
  IL6Ra-bind UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  HEMATOPO_REC_S_F1 UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
UniProt A0A0B8RVZ4 ENTREZGENE
  A0A5G2QEJ3_PIG UniProtKB/TrEMBL
  A0A8D1IRG7_PIG UniProtKB/TrEMBL
  A0A8D1ITI9_PIG UniProtKB/TrEMBL
  A0A8D1S9Z4_PIG UniProtKB/TrEMBL
  A0A8D1SCC7_PIG UniProtKB/TrEMBL
  F1SKK0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87033 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-25 CSF2RB  colony stimulating factor 2 receptor subunit beta  CSF2RB  colony stimulating factor 2 receptor beta common subunit  Symbol and/or name change 5135510 APPROVED