CDH5 (cadherin 5) - Rat Genome Database

Name: CDH5
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: CDH5 (cadherin 5) Sus scrofa

Analyze

Symbol:

CDH5

Name:

cadherin 5

RGD ID:

14171588

Description:

ENCODES a protein that exhibits beta-catenin binding (inferred); BMP receptor binding (inferred); calcium ion binding (inferred); INVOLVED IN regulation of complement-dependent cytotoxicity; blood vessel maturation (ortholog); cell-cell adhesion (ortholog); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); Breast Neoplasms (ortholog); cataract 5 multiple types (ortholog); FOUND IN adherens junction (ortholog); cell junction (ortholog); cell-cell junction (ortholog); INTERACTS WITH carvedilol; deoxynivalenol

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cadherin 5, type 2 (vascular endothelium); cadherin-5; vascular endothelial cadherin; VE cadherin

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CDH5 (cadherin 5)	HGNC	Ensembl, Inparanoid, NCBI, OrthoDB
Mus musculus (house mouse):	Cdh5 (cadherin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Cdh5 (cadherin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cdh5 (cadherin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CDH5 (cadherin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CDH5 (cadherin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cdh5 (cadherin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CDH5 (cadherin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cdh5 (cadherin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	27,108,597 - 27,142,177 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	27,108,560 - 27,142,145 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant dyskeratosis congenita 6 (ISO)

Breast Neoplasms (ISO)

cataract 5 multiple types (ISO)

Chromosome 16q12 Duplication Syndrome (ISO)

Colorectal Neoplasms (ISO)

coronary artery disease (ISO)

Experimental Liver Cirrhosis (ISO)

exudative vitreoretinopathy (ISO)

malignant mesothelioma (ISO)

Marfanoid Mental Retardation Syndrome, Autosomal (ISO)

No-Reflow Phenomenon (ISO)

primary biliary cholangitis (ISO)

pulmonary hypertension (ISO)

Right Ventricular Hypertrophy (ISO)

thyroid gland carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

carvedilol (EXP)

deoxynivalenol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adherens junction organization (IBA,IEA)

bicellular tight junction assembly (IEA)

blood vessel endothelial cell migration (IEA)

blood vessel maturation (IEA,ISO)

calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (IBA)

cell adhesion (IEA)

cell migration (IBA)

cell morphogenesis (IBA)

cell-cell adhesion (IEA,ISO)

cell-cell adhesion mediated by cadherin (IBA,IEA)

cell-cell junction assembly (IBA,IEA)

endothelial cell morphogenesis (IEA,ISS)

homophilic cell adhesion via plasma membrane adhesion molecules (IEA)

intracellular calcium ion homeostasis (IEA)

negative regulation of cell population proliferation (IEA,ISO)

negative regulation of endothelial cell apoptotic process (IEA,ISO)

negative regulation of inflammatory response (IEA)

negative regulation of microtubule polymerization (IEA)

obsolete positive regulation of protein dephosphorylation (IEA)

positive regulation of angiogenesis (IEA)

positive regulation of BMP signaling pathway (IEA)

positive regulation of cell migration (IEA)

positive regulation of establishment of endothelial barrier (IEA)

positive regulation of gene expression (IEA)

positive regulation of protein-containing complex assembly (IEA)

protein localization to bicellular tight junction (IEA)

regulation of complement-dependent cytotoxicity (IMP)

regulation of establishment of cell polarity (IEA,ISS)

regulation of protein phosphorylation (IEA)

regulation of vascular permeability (IEA)

transforming growth factor beta receptor signaling pathway (IEA)

Cellular Component

adherens junction (IBA,IEA,ISS)

anchoring junction (IEA)

bicellular tight junction (IBA,IEA)

catenin complex (IBA)

cell junction (IEA,ISS)

cell periphery (IEA)

cell surface (IEA)

cell-cell junction (IEA,ISS)

cytoplasm (IEA,ISS)

external side of plasma membrane (IEA)

nuclear membrane (IEA)

nucleoplasm (IEA)

plasma membrane (IEA)

Molecular Function

beta-catenin binding (IBA,IEA)

BMP receptor binding (IEA)

cadherin binding (IBA)

calcium ion binding (IEA)

fibrinogen binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

protein phosphatase binding (IBA,IEA)

protein tyrosine kinase binding (IEA)

signaling receptor binding (IEA)

transmembrane transporter binding (IEA)

vascular endothelial growth factor receptor 2 binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

sphingosine 1-phosphate signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

References

Additional References at PubMed

PMID:9918866	PMID:14681463	PMID:17060906	PMID:17145712	PMID:18019273	PMID:19519369	PMID:22301074	PMID:24280217	PMID:30032202

Genomics

Comparative Map Data

CDH5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	27,108,597 - 27,142,177 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	27,108,560 - 27,142,145 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

CDH5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	66,366,691 - 66,404,784 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	66,366,690 - 66,404,784 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	66,400,594 - 66,438,687 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	64,958,064 - 64,996,190 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	64,958,063 - 64,996,189	NCBI
Celera	16	50,909,482 - 50,944,587 (+)	NCBI		Celera
Cytogenetic Map	16	q21	NCBI
HuRef	16	52,277,104 - 52,314,656 (+)	NCBI		HuRef
CHM1_1	16	67,807,788 - 67,845,939 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	72,161,057 - 72,198,985 (+)	NCBI		T2T-CHM13v2.0

Cdh5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	104,828,247 - 104,871,136 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	104,828,257 - 104,871,143 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	104,101,613 - 104,144,504 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	104,101,625 - 104,144,511 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	106,625,525 - 106,668,402 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	106,990,828 - 107,033,630 (+)	NCBI		MGSCv36	mm8
Celera	8	108,332,486 - 108,375,834 (+)	NCBI		Celera
Cytogenetic Map	8	D3	NCBI
cM Map	8	53.04	NCBI

Cdh5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	821,875 - 860,931 (-)	NCBI		GRCr8
mRatBN7.2	19	815,415 - 854,478 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	815,411 - 854,368 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	813,201 - 850,834 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	1,580,002 - 1,617,637 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	855,206 - 892,839 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	1,025,122 - 1,074,333 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	1,023,683 - 1,074,365 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	1,022,710 - 1,072,784 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	779,350 - 816,108 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	779,507 - 1,129,968 (-)	NCBI
Celera	19	805,477 - 843,688 (-)	NCBI		Celera
Cytogenetic Map	19	p14	NCBI

Cdh5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955433	22,967,960 - 22,992,924 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955433	22,957,718 - 22,994,515 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDH5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	75,868,996 - 75,907,239 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	81,781,113 - 81,819,347 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	46,684,545 - 46,722,740 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	65,787,426 - 65,825,360 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	65,787,370 - 65,825,360 (+)	Ensembl	panpan1.1		panPan2

CDH5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	82,830,505 - 82,863,931 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	82,830,939 - 82,863,882 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	82,820,021 - 82,852,406 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	83,268,385 - 83,300,767 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	83,268,594 - 83,300,713 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	83,091,349 - 83,123,732 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	82,784,959 - 82,805,255 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	83,417,122 - 83,449,500 (-)	NCBI		UU_Cfam_GSD_1.0

Cdh5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	42,814,114 - 42,850,388 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	16,738,748 - 16,775,123 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	16,738,772 - 16,775,000 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDH5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	52,059,987 - 52,098,595 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	52,060,013 - 52,100,405 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	23,817,264 - 23,856,166 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdh5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	20,033,008 - 20,057,595 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624746	20,028,952 - 20,068,029 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CDH5
874 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	5	14	12	23	3	6	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001001649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB046120	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AEMK02000040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK239850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK395576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU714329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01081569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y13919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000039471 ⟹ ENSSSCP00000038553

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	27,118,058 - 27,141,994 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000065433 ⟹ ENSSSCP00000043240

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	27,108,597 - 27,142,167 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000065677 ⟹ ENSSSCP00000047033

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	6	27,118,080 - 27,142,177 (+)	Ensembl

RefSeq Acc Id:

NM_001001649 ⟹ NP_001001649

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	6	27,108,560 - 27,142,145 (+)	NCBI

Sequence:

show sequence

GGCTCCCCTCGAGAGGCTGTGGGCCAAGCTCCCCGGCACACTCAGCCCCGGACGGGCGGCAGAC
AGCCAGACAGACGGACACACATCTCGGCCCCCGGCACGACCGGCCCCTCCTGGGAAGATGCAGG
TGCTCGTGATGCTGCTCGCTGCAGCCGGCACCTACCTGGGCCTGCTGACAGCACCTACAGCTGC
CTCGAACCCTGGCCGACAGGACACCCCCAGCACGCTGCCCCTTCACCGGCGCCAGAAGAGAGAC
TGGATCTGGAACCAGATGCACATCGACGAAGAGAAAAACGGCTCGCTGCCCCATTACGTGGGCA
AGATTAAATCCAGCGTGAACCACAAGAACACCAAGTACCAGCTCAAAGGCGAGTCCGCCGGCAA
GGTCTTCCGGGTGGATGAGAACACGGGGGATGTGTACGCCTTCGAGAGGCTGGACAGGGAGAAG
ATCCCTGAGTACCAGCTCGTCGCCCTCGTGGTGGACAAGAACACTGAGAAGAACCTGGAGTCTC
CTTCCAGCTTCACCATCAAAGTTCACGATATCAACGACAACTGGCCTGTGTTCACACAGCTCGT
GTTCAACGCCTCCGTGCCTGAGATGTCAGTGATAGGGACCTCGGTCATCCAGTTGACAGCAGTA
GACGCAGATGACCCCACGGTGGCAGACCATGCCTCTGTCATATACCGGCTCAAGGAGGGAGAAG
AACACTTCCGCATCCGTGGTCCTGGACTCATTGAAACGGCCAGCAAAAATCTGGACCGAGAGAC
AGTGCCCATGTACAAGATCGTGGTGGAAACACAAGATGCCCAGGGCCTCCGTGGGGACTCGGGC
ACAGCCACTGTGTTCATCACTCTGCAGGACGTCAACGACAACTTCCCCGTCTTCACCCAGACCA
GGTACACATTTTCTGTGCCTGAAGACATCCGTGTGGGCAGCCCCCTAGGCTCTCTGTTTGTCAA
GGACCCAGATGAGCCCCAAAACCGGAAAACCAAGTACAGCATCGTGCAGGGCGAGTACAGGGAC
ACCTTCACCATCGAGCCGGACCCCACCCGCAACGAAGGCATCATCAAGCCCATGAAGCCCCTGG
ACTATGAACGCATCCAGCAATACAGCTTCACCATCGAGGCCACAGACCCCACCATCGACCTCCG
CTACCTGAGTGGCACCTCCACCAAGAACATCGCCCGTGTCATCATCAACGTCACAGACGTGGAC
GAGCCCCCCAACTTCAAGCAGCCCTTCTACCACTTCCAGCTGCGGGAGAATGAGAAGAAACCTT
GGATCGGCTCAGTGCTGGCCGTGGACCCGGACGCCGCTCAGCGGAGCATCGGATACTCCATCCG
CAGGACCAGTGACAAGGGCCAGTTCTTCGGAATAAACAAGCACGGGAATATTTACAATGTGAAA
GAACTGGACAGAGAAGTCTACCCCTGGTATAACCTGACAGTGGAGGCCAAAGAGCTGGATTCTA
GGGGCACCCCCACGGGCAAGGAATCCATTGTGCAGGTCCACATTGAAGTTCTGGATGAGAACGA
CAACGCCCCGGAGTTTGCCAAGCCCTATGAGGCCAAAGTGTGTGAGGACGCCCCCCAGGGCAAG
CTGGTTGTGCAAATTTCAGCAATAGACAAGGATGTAACACCACGAGATGTGAAGTTCAAGTTCT
CCCTGAGCACTGAGGACAGCAACTTCACCCTCACGGATAATCACGATAACACAGCCAACATCAC
AGTCAAGCACGGGTATTTTGACCGGGAGCGTGCCAAGGTCCACCACCTTCCCATACTCATCTCG
GACAACGGGAGGCCGAGCCTCACAGGCACCAGCACGCTGCACGTGACCGTGTGCAAGTGCAACG
AGCGGGGCGAGTTCACCTTGTGCGAGGAGATGGGCGCCCAAGTGGGCGTCAGCATCCAGGCCCT
GGTAGCCATCTTCCTCTGCATCCTCACCATCGCAGTGATCTCCCTCCTCGTGTACCTGCGGCGG
CGTCTCCGGAAGCAGGCTCGCGCCCATGGCAAGAGCGTGCCGGAGATCCACGAGCAGCTGGTCA
CCTACGATGAGGAGGGCGGCGGCGAGATGGACACCACCAGCTACGACGTCTCGGTTCTCAACTC
AGTGCGCCACGGCGGGGCCAAGCCCCCGCGGCCGGCGCTGGATGCGCGACCGTCCCTCTACGCG
CAGGTGCAGAAGCCGCCACGTCACGCACCCGGGGCGCATGCGCCAGGGGAGATGGCGGCGATGA
TCGAGGTGAAGAAGGATGAGGCGGACCATGACGGCGGCGGCCCTCCCTACGACACGCTGCATAT
CTTTGGCTACGAGGGCGCTGAGTCCATCGCCGAGTCCCTCAGCTCCTTGGGCACCGACTCATCC
GACTCTGACATCGATTATGACTTCCTCAATGACTGGGGGCCCAGGTTCAAGATGCTGGCCGAGC
TGTACGGCTCAGACCCCCGAGAGGAGCTGCTGTATTAGGAGACCCAAACCACCGCGGCTTAGGC
TAGTCAGACATGAGGCACTGAGCCCTTGAATTGTAGCACTCATGCCCCAGCCTAAGAGCCCTTC
CTCCTGGGTCCCAGAGACCTCATCACCTTGGGTAGCACAACCAAGTCCCTGAAATGTCCAGGAA
CATCTTTCAGCAACGGCTACTCACAAAATGCTGGAAAATCCAGGATGGTGTTCTGTCTGGGCTG
GGCATCCTGTCACCCGGGACCCAGGGTCCAACTCAAGCCTTTCTCTGGCTCCTCAAAGCAGCTT
ATTATCGACTCCCAAGGGGAATTCTTCCTCTGAGGTCAGAGAGCCTCATGGGGAAGAATTCCCC
TGAATTCAGAGCATACACCCTCCAGAGTCCCCAGCACTCCTCAGCCTCTCCTCAGACCTGTCAA
GAGGGAGGAAGGGCCCCTGACAGTTCCTGTGGTGACCTTGCTGGCCTGCTACGCTTGTAACTAT
GCTGTGCTGAGTGTTGACAACTCATCCAAAGTCAGGGAAATGGTTTGTTGAACTTCAAAGCAAC
TGTGAATTCATCCTGGAGGGATAGTGGAGACCAAGTGTGACAGATCATAGGGTGAGGGCCACTC
CCACTCCCTCCAGAGAGGGCCTGGAGTCACTGTGACCCCAACTTGAGACTCATGACACCGCTCC
AGTTTTGCCTGGCAAGTGGGGCCGATGTTCCCAGAGCAGAAGACCTCTGCCCATCTCCCCTGGT
CACTCGCTCATGCTCTTTTCCTTTTCTCTCCATCCAGTCTTGATCTCTTGACTTAGAGGCCCTC
AAGATGTGACCCACATCAACTCTGGCCAAAGTCCAAACCCAAACATGACTGCATAACAGAGCTG
TGCCATTTGCCTTTACACCTCATCATGGCCACATCTCAGGGAACCCCAGCAGGGCCTCATTCCT
GCAGGGGGCAAGGCCCCTGCCCAAGCCCTGCAGTCACCCATGCATCTCGCACTTATGGAACTTT
CCACTGCAAACACACCTCTGGGAAATGGCTTCACTCAACAGGAGGGGATGGGGGAAGGAAGCAA
ACTCTTCAGCACACCCTTTGACATGAACTAAGTTTCCTGCTTTGGGAAAGGCTCCCCCCACAAT
TCAGGGGACTGTAGATAACACTGACTTTTTGCTTTTAACTAATAACTACTTTTTCACTTTTTTA
ACTAATAATACTTACACATTTCTAGCTCTCACAAATAGAATAAGGATTTTTTGCATAATGAGCT
GGTTGCTATTTAGGTTAACAACTTAAATTCAGGTTTTTTTAGTTGGATAAACCAATTCCTATAA
CCTTCTATTTCCTATCATTGTGGTAATTGCTTTAATGATAATGACTATATATATATTGGCTGCA
CGAATGCATGGGACATACTGTATTTTTTTTATAATTCTGAATTCAGAG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001001649	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACF37109	(Get FASTA)	NCBI Sequence Viewer
	BAB82983	(Get FASTA)	NCBI Sequence Viewer
	CAA74225	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000043240.3
	ENSSSCP00000047033
	ENSSSCP00000047033.1
	ENSSSCP00005003935.1
	ENSSSCP00005003952.1
	ENSSSCP00055035372.1
	ENSSSCP00065006677.1
GenBank Protein	O02840	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001001649 ⟸ NM_001001649
- Peptide Label:	precursor
- UniProtKB:	O02840 (UniProtKB/Swiss-Prot), B4YYE0 (UniProtKB/TrEMBL), A0A8D1XNS4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQVLVMLLAAAGTYLGLLTAPTAASNPGRQDTPSTLPLHRRQKRDWIWNQMHIDEEKNGSLPHY VGKIKSSVNHKNTKYQLKGESAGKVFRVDENTGDVYAFERLDREKIPEYQLVALVVDKNTEKNL ESPSSFTIKVHDINDNWPVFTQLVFNASVPEMSVIGTSVIQLTAVDADDPTVADHASVIYRLKE GEEHFRIRGPGLIETASKNLDRETVPMYKIVVETQDAQGLRGDSGTATVFITLQDVNDNFPVFT QTRYTFSVPEDIRVGSPLGSLFVKDPDEPQNRKTKYSIVQGEYRDTFTIEPDPTRNEGIIKPMK PLDYERIQQYSFTIEATDPTIDLRYLSGTSTKNIARVIINVTDVDEPPNFKQPFYHFQLRENEK KPWIGSVLAVDPDAAQRSIGYSIRRTSDKGQFFGINKHGNIYNVKELDREVYPWYNLTVEAKEL DSRGTPTGKESIVQVHIEVLDENDNAPEFAKPYEAKVCEDAPQGKLVVQISAIDKDVTPRDVKF KFSLSTEDSNFTLTDNHDNTANITVKHGYFDRERAKVHHLPILISDNGRPSLTGTSTLHVTVCK CNERGEFTLCEEMGAQVGVSIQALVAIFLCILTIAVISLLVYLRRRLRKQARAHGKSVPEIHEQ LVTYDEEGGGEMDTTSYDVSVLNSVRHGGAKPPRPALDARPSLYAQVQKPPRHAPGAHAPGEMA AMIEVKKDEADHDGGGPPYDTLHIFGYEGAESIAESLSSLGTDSSDSDIDYDFLNDWGPRFKML AELYGSDPREELLY hide sequence

Ensembl Acc Id:

ENSSSCP00000038553 ⟸ ENSSSCT00000039471

Ensembl Acc Id:

ENSSSCP00000043240 ⟸ ENSSSCT00000065433

Ensembl Acc Id:

ENSSSCP00000047033 ⟸ ENSSSCT00000065677

Protein Domains

Cadherin

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000035772	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005004254	UniProtKB/TrEMBL
	ENSSSCG00055022576	UniProtKB/Swiss-Prot
	ENSSSCG00065012277	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000065433.3	UniProtKB/TrEMBL
	ENSSSCT00000065677	ENTREZGENE
	ENSSSCT00000065677.3	UniProtKB/TrEMBL
	ENSSSCT00005006803.1	UniProtKB/TrEMBL
	ENSSSCT00005006823.1	UniProtKB/TrEMBL
	ENSSSCT00055044391.1	UniProtKB/Swiss-Prot
	ENSSSCT00065016373.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.900.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Cadherin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin_cytoplasmic-dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Catenin_binding_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	ssc:414737	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	CDH5	ENTREZGENE
PANTHER	PTHR24027	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR24027:SF89	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Cadherin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	CADHERIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	CADHERIN_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CADHERIN_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	SM00112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF49313	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A287AGS7_PIG	UniProtKB/TrEMBL
	A0A8D1XNS4	ENTREZGENE, UniProtKB/TrEMBL
	B4YYE0	ENTREZGENE, UniProtKB/TrEMBL
	CADH5_PIG	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8WNW5_PIG	UniProtKB/TrEMBL
UniProt Secondary	A0A4X1UPT3	UniProtKB/TrEMBL
VGNC ID	VGNC:86486	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Annotations - PID (archival)