DAO (D-amino acid oxidase) - Rat Genome Database

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Gene: DAO (D-amino acid oxidase) Sus scrofa
Analyze
Symbol: DAO
Name: D-amino acid oxidase
RGD ID: 14171512
Description: ENCODES a protein that exhibits D-amino-acid oxidase activity; INVOLVED IN D-amino acid catabolic process; leucine metabolic process (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); autistic disorder (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN mitochondrial outer membrane (ortholog); INTERACTS WITH 5-methyl-pyrazole-3-carboxylic acid; chlorpromazine; sodium benzoate
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: D-amino-acid oxidase; DAAO; DAMOX; DAO1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,929,215 - 41,950,633 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11441,931,549 - 41,950,628 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,473,515 - 44,492,595 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q2.1-q2.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1673125   PMID:2572224   PMID:2575382   PMID:2888479   PMID:2893757   PMID:2901989   PMID:2905598   PMID:6120171   PMID:6124543   PMID:6129252   PMID:8104765   PMID:8755502  
PMID:8864836   PMID:9153426   PMID:14681463   PMID:15928834   PMID:16245349   PMID:18544534   PMID:18634432   PMID:22271930  


Genomics

Comparative Map Data
DAO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,929,215 - 41,950,633 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11441,931,549 - 41,950,628 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,473,515 - 44,492,595 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q2.1-q2.3NCBI
DAO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812108,880,092 - 108,901,043 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl12108,858,932 - 108,901,043 (+)EnsemblGRCh38hg38GRCh38
GRCh3712109,273,868 - 109,294,819 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612107,797,986 - 107,818,839 (+)NCBINCBI36hg18NCBI36
Build 3412107,776,332 - 107,797,162NCBI
Celera12108,942,740 - 108,963,590 (+)NCBI
Cytogenetic Map12q24.11NCBI
HuRef12106,338,463 - 106,359,320 (+)NCBIHuRef
CHM1_112109,241,476 - 109,262,347 (+)NCBICHM1_1
T2T-CHM13v2.012108,854,786 - 108,875,798 (+)NCBI
Dao
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,137,696 - 114,163,736 (+)NCBIGRCm39mm39
GRCm39 Ensembl5114,141,764 - 114,163,743 (+)Ensembl
GRCm385113,999,635 - 114,025,675 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,003,703 - 114,025,682 (+)EnsemblGRCm38mm10GRCm38
MGSCv375114,453,835 - 114,475,469 (+)NCBIGRCm37mm9NCBIm37
MGSCv365114,270,835 - 114,285,905 (+)NCBImm8
Celera5111,106,565 - 111,127,023 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.93NCBI
Dao
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21242,592,342 - 42,613,046 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1242,592,343 - 42,612,741 (-)Ensembl
Rnor_6.01248,353,691 - 48,373,647 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,354,196 - 48,365,784 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,135,334 - 50,157,417 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,627,593 - 43,648,332 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11243,490,980 - 43,511,720 (-)NCBI
Celera1244,196,549 - 44,215,768 (-)NCBICelera
Cytogenetic Map12q16NCBI
Dao
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,095,300 - 10,127,666 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545510,095,597 - 10,127,244 (+)NCBIChiLan1.0ChiLan1.0
DAO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112109,849,995 - 109,870,065 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12109,849,995 - 109,870,065 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012106,453,807 - 106,475,409 (+)NCBIMhudiblu_PPA_v0panPan3
DAO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12618,032,663 - 18,057,277 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2618,033,392 - 18,057,238 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2617,744,673 - 17,773,938 (+)NCBI
ROS_Cfam_1.02618,371,860 - 18,401,188 (-)NCBI
ROS_Cfam_1.0 Ensembl2618,376,518 - 18,395,445 (-)Ensembl
UMICH_Zoey_3.12617,954,290 - 17,983,467 (+)NCBI
UNSW_CanFamBas_1.02618,362,722 - 18,391,870 (-)NCBI
UU_Cfam_GSD_1.02618,381,507 - 18,410,821 (-)NCBI
Dao
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118144,717,426 - 144,736,206 (-)NCBI
SpeTri2.0NW_004936769744,862 - 758,086 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111104,080,915 - 104,104,017 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl11104,081,672 - 104,106,222 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037140,993,522 - 141,016,334 (-)NCBIVero_WHO_p1.0
Dao
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,105,133 - 12,116,604 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474712,094,658 - 12,117,000 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system
High
Medium 5 10 2
Low 2 3 13
Below cutoff 1 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000010894   ⟹   ENSSSCP00000010609
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1441,931,541 - 41,950,633 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000041453   ⟹   ENSSSCP00000037253
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1441,929,215 - 41,947,105 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000043498   ⟹   ENSSSCP00000047768
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1441,931,541 - 41,950,633 (-)Ensembl
RefSeq Acc Id: NM_214066   ⟹   NP_999231
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11441,931,549 - 41,950,628 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_999231 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA30985 (Get FASTA)   NCBI Sequence Viewer  
  AAA31025 (Get FASTA)   NCBI Sequence Viewer  
  AAA31026 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_999231   ⟸   NM_214066
- UniProtKB: P00371 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010609   ⟸   ENSSSCT00000010894
RefSeq Acc Id: ENSSSCP00000037253   ⟸   ENSSSCT00000041453
RefSeq Acc Id: ENSSSCP00000047768   ⟸   ENSSSCT00000043498
Protein Domains
DAO


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009942 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005045054 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00015008169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00025030743 UniProtKB/TrEMBL
  ENSSSCG00030059512 UniProtKB/TrEMBL
  ENSSSCG00035071801 UniProtKB/TrEMBL
  ENSSSCG00040004294 UniProtKB/TrEMBL
  ENSSSCG00045017345 UniProtKB/TrEMBL
  ENSSSCG00055026300 UniProtKB/TrEMBL
  ENSSSCG00060076998 UniProtKB/TrEMBL
  ENSSSCG00065026997 UniProtKB/TrEMBL
  ENSSSCG00070003140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000010609 UniProtKB/TrEMBL
  ENSSSCP00000037253 UniProtKB/TrEMBL
  ENSSSCP00000047768 UniProtKB/TrEMBL
  ENSSSCP00005045526 UniProtKB/Swiss-Prot
  ENSSSCP00005045531 UniProtKB/TrEMBL
  ENSSSCP00005045539 UniProtKB/TrEMBL
  ENSSSCP00015004255 UniProtKB/TrEMBL
  ENSSSCP00015004305 UniProtKB/Swiss-Prot
  ENSSSCP00015004352 UniProtKB/TrEMBL
  ENSSSCP00025017906 UniProtKB/TrEMBL
  ENSSSCP00025017969 UniProtKB/TrEMBL
  ENSSSCP00025018076 UniProtKB/TrEMBL
  ENSSSCP00030038191 UniProtKB/TrEMBL
  ENSSSCP00030038219 UniProtKB/TrEMBL
  ENSSSCP00030038279 UniProtKB/TrEMBL
  ENSSSCP00035040934 UniProtKB/TrEMBL
  ENSSSCP00035040956 UniProtKB/TrEMBL
  ENSSSCP00035040970 UniProtKB/TrEMBL
  ENSSSCP00040002139 UniProtKB/TrEMBL
  ENSSSCP00040002143 UniProtKB/TrEMBL
  ENSSSCP00040002148 UniProtKB/TrEMBL
  ENSSSCP00045020474 UniProtKB/TrEMBL
  ENSSSCP00045020551 UniProtKB/TrEMBL
  ENSSSCP00045020613 UniProtKB/TrEMBL
  ENSSSCP00055041571 UniProtKB/TrEMBL
  ENSSSCP00055041665 UniProtKB/TrEMBL
  ENSSSCP00055041745 UniProtKB/TrEMBL
  ENSSSCP00060046680 UniProtKB/TrEMBL
  ENSSSCP00060046712 UniProtKB/TrEMBL
  ENSSSCP00060046726 UniProtKB/TrEMBL
  ENSSSCP00065015274 UniProtKB/TrEMBL
  ENSSSCP00065015285 UniProtKB/TrEMBL
  ENSSSCP00065015289 UniProtKB/TrEMBL
  ENSSSCP00070004865 UniProtKB/TrEMBL
  ENSSSCP00070004870 UniProtKB/Swiss-Prot
  ENSSSCP00070004877 UniProtKB/TrEMBL
  ENSSSCP00070004886 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000010894 UniProtKB/TrEMBL
  ENSSSCT00000041453 UniProtKB/TrEMBL
  ENSSSCT00000043498 UniProtKB/TrEMBL
  ENSSSCT00005072766 UniProtKB/Swiss-Prot
  ENSSSCT00005072772 UniProtKB/TrEMBL
  ENSSSCT00005072783 UniProtKB/TrEMBL
  ENSSSCT00015010804 UniProtKB/TrEMBL
  ENSSSCT00015010951 UniProtKB/Swiss-Prot
  ENSSSCT00015011064 UniProtKB/TrEMBL
  ENSSSCT00025042055 UniProtKB/TrEMBL
  ENSSSCT00025042215 UniProtKB/TrEMBL
  ENSSSCT00025042473 UniProtKB/TrEMBL
  ENSSSCT00030083119 UniProtKB/TrEMBL
  ENSSSCT00030083175 UniProtKB/TrEMBL
  ENSSSCT00030083295 UniProtKB/TrEMBL
  ENSSSCT00035097106 UniProtKB/TrEMBL
  ENSSSCT00035097143 UniProtKB/TrEMBL
  ENSSSCT00035097173 UniProtKB/TrEMBL
  ENSSSCT00040005653 UniProtKB/TrEMBL
  ENSSSCT00040005658 UniProtKB/TrEMBL
  ENSSSCT00040005664 UniProtKB/TrEMBL
  ENSSSCT00045029540 UniProtKB/TrEMBL
  ENSSSCT00045029642 UniProtKB/TrEMBL
  ENSSSCT00045029728 UniProtKB/TrEMBL
  ENSSSCT00055052032 UniProtKB/TrEMBL
  ENSSSCT00055052149 UniProtKB/TrEMBL
  ENSSSCT00055052244 UniProtKB/TrEMBL
  ENSSSCT00060105930 UniProtKB/TrEMBL
  ENSSSCT00060105980 UniProtKB/TrEMBL
  ENSSSCT00060106002 UniProtKB/TrEMBL
  ENSSSCT00065036364 UniProtKB/TrEMBL
  ENSSSCT00065036382 UniProtKB/TrEMBL
  ENSSSCT00065036391 UniProtKB/TrEMBL
  ENSSSCT00070005959 UniProtKB/TrEMBL
  ENSSSCT00070005965 UniProtKB/Swiss-Prot
  ENSSSCT00070005977 UniProtKB/TrEMBL
  ENSSSCT00070005990 UniProtKB/TrEMBL
InterPro D-amino_acid_oxidase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD-dep_OxRdtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397134 UniProtKB/Swiss-Prot
NCBI Gene DAO ENTREZGENE
PANTHER PTHR11530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DAO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF D-aa_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DAO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287AV04_PIG UniProtKB/TrEMBL
  A0A4X1SRS8_PIG UniProtKB/TrEMBL
  A0A4X1SRU8_PIG UniProtKB/TrEMBL
  A0A4X1SS08_PIG UniProtKB/TrEMBL
  A0A5S6G733_PIG UniProtKB/TrEMBL
  A0A5S6HBK3_PIG UniProtKB/TrEMBL
  A0A8D1X294_PIG UniProtKB/TrEMBL
  A0A8D1X409_PIG UniProtKB/TrEMBL
  OXDA_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q28382_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87155 ENTREZGENE