FOXH1 (forkhead box H1) - Rat Genome Database

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Gene: FOXH1 (forkhead box H1) Sus scrofa
Analyze
Symbol: FOXH1
Name: forkhead box H1
RGD ID: 14171430
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); axial mesoderm development (ortholog); determination of left/right symmetry (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH agnathia-otocephaly complex (ortholog); Brown-Vialetto-Van Laere syndrome 2 (ortholog); Conotruncal Cardiac Defects (ortholog); FOUND IN activin responsive factor complex (inferred); chromatin (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: forkhead box protein H1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4322,838 - 324,481 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14320,610 - 324,570 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24411,723 - 415,556 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
FOXH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4322,838 - 324,481 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14320,610 - 324,570 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24411,723 - 415,556 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOXH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,473,412 - 144,475,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,473,412 - 144,475,849 (-)EnsemblGRCh38hg38GRCh38
GRCh378145,698,795 - 145,701,232 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,670,306 - 145,672,526 (-)NCBINCBI36Build 36hg18NCBI36
Build 348145,670,316 - 145,672,526NCBI
Celera8141,874,214 - 141,876,817 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,812,639 - 140,814,791 (-)NCBIHuRef
CHM1_18145,737,374 - 145,739,977 (-)NCBICHM1_1
T2T-CHM13v2.08145,643,152 - 145,645,589 (-)NCBIT2T-CHM13v2.0
Foxh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,552,029 - 76,554,286 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,552,425 - 76,554,148 (-)EnsemblGRCm39 Ensembl
GRCm381576,667,829 - 76,671,614 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,668,225 - 76,669,948 (-)EnsemblGRCm38mm10GRCm38
MGSCv371576,498,737 - 76,500,303 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,495,562 - 76,497,128 (-)NCBIMGSCv36mm8
Celera1578,161,919 - 78,163,485 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.24NCBI
Foxh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,268,608 - 110,272,105 (-)NCBIGRCr8
mRatBN7.27108,387,969 - 108,391,566 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,387,969 - 108,390,049 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,129,799 - 110,131,879 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,353,375 - 112,355,455 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,314,210 - 112,316,290 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,730,307 - 117,733,076 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,730,307 - 117,732,387 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,718,390 - 117,720,470 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,717,890 - 114,719,455 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,752,036 - 114,753,685 (-)NCBI
Celera7104,737,872 - 104,739,952 (-)NCBICelera
Cytogenetic Map7q34NCBI
Foxh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554543,094,033 - 3,095,512 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554543,094,015 - 3,096,060 (-)NCBIChiLan1.0ChiLan1.0
FOXH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,965,218 - 161,969,422 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18137,494,284 - 137,498,488 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08141,240,691 - 141,244,381 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18144,229,228 - 144,231,829 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8144,225,933 - 144,232,736 (-)Ensemblpanpan1.1panPan2
FOXH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,883,554 - 37,887,324 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,882,687 - 37,885,319 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,844,309 - 37,848,077 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,357,286 - 38,361,056 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,356,419 - 38,358,928 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11338,049,036 - 38,052,801 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01338,157,673 - 38,161,434 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,634,120 - 38,637,890 (-)NCBIUU_Cfam_GSD_1.0
Foxh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303361,968 - 365,427 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364707,789,541 - 7,791,039 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364707,789,486 - 7,791,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,685,137 - 138,688,451 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,685,626 - 138,687,144 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660391,166,573 - 1,171,132 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Foxh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,386,281 - 12,387,774 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,384,728 - 12,388,234 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FOXH1
45 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system reproductive system respiratory system
High
Medium
Low 6 2 1 3 20
Below cutoff 3 2 1 3 3 1

Sequence


RefSeq Acc Id: ENSSSCT00000006481   ⟹   ENSSSCP00000006310
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4322,838 - 324,481 (+)Ensembl
RefSeq Acc Id: XM_001925280   ⟹   XP_001925315
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14320,610 - 324,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013996400   ⟹   XP_013851854
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14320,610 - 324,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021090533   ⟹   XP_020946192
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14320,610 - 324,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021090534   ⟹   XP_020946193
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14320,610 - 324,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021090535   ⟹   XP_020946194
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14320,610 - 324,570 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020946192   ⟸   XM_021090533
- Peptide Label: isoform X1
- UniProtKB: A0A8D1EPH6 (UniProtKB/TrEMBL),   A0A8D1UBE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020946193   ⟸   XM_021090534
- Peptide Label: isoform X1
- UniProtKB: A0A8D1EPH6 (UniProtKB/TrEMBL),   A0A8D1UBE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020946194   ⟸   XM_021090535
- Peptide Label: isoform X2
- UniProtKB: A0A8D1UBE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_001925315   ⟸   XM_001925280
- Peptide Label: isoform X1
- UniProtKB: A0A8D1EPH6 (UniProtKB/TrEMBL),   A0A8D1UBE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013851854   ⟸   XM_013996400
- Peptide Label: isoform X1
- UniProtKB: A0A8D1EPH6 (UniProtKB/TrEMBL),   A0A8D1UBE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000006310   ⟸   ENSSSCT00000006481
Protein Domains
Fork-head


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000005902 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025053244 UniProtKB/TrEMBL
  ENSSSCG00030002230 UniProtKB/TrEMBL
  ENSSSCG00035056234 UniProtKB/TrEMBL
  ENSSSCG00040045476 UniProtKB/TrEMBL
  ENSSSCG00045013322 UniProtKB/TrEMBL
  ENSSSCG00050054260 UniProtKB/TrEMBL
  ENSSSCG00055026045 UniProtKB/TrEMBL
  ENSSSCG00060014465 UniProtKB/TrEMBL
  ENSSSCG00065019144 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006481 ENTREZGENE
  ENSSSCT00000006481.4 UniProtKB/TrEMBL
  ENSSSCT00025072825.1 UniProtKB/TrEMBL
  ENSSSCT00030002843.1 UniProtKB/TrEMBL
  ENSSSCT00035075058.1 UniProtKB/TrEMBL
  ENSSSCT00040061049.1 UniProtKB/TrEMBL
  ENSSSCT00045022707.1 UniProtKB/TrEMBL
  ENSSSCT00050073975.1 UniProtKB/TrEMBL
  ENSSSCT00055051436.1 UniProtKB/TrEMBL
  ENSSSCT00060019161.1 UniProtKB/TrEMBL
  ENSSSCT00065025467.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro FH_FOXH1 UniProtKB/TrEMBL
  Fork_head_dom UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report ssc:100154027 UniProtKB/TrEMBL
NCBI Gene FOXH1 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN H1 UniProtKB/TrEMBL
  FORKHEAD BOX PROTEIN H1 UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/TrEMBL
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A8D1EPH6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1UBE4 ENTREZGENE, UniProtKB/TrEMBL
  F1RSP3_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88207 ENTREZGENE