MIR19B-2 (microRNA mir-19b-2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: MIR19B-2 (microRNA mir-19b-2) Sus scrofa
Analyze
Symbol: MIR19B-2
Name: microRNA mir-19b-2
RGD ID: 14165585
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: microRNA 19b-2; ssc-mir-19b-2
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX110,113,855 - 110,113,934 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X110,113,855 - 110,113,934 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X126,199,650 - 126,199,729 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:19917043   PMID:21312241   PMID:24499489  


Genomics

Comparative Map Data
MIR19B-2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX110,113,855 - 110,113,934 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X110,113,855 - 110,113,934 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X126,199,650 - 126,199,729 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIR19B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X134,169,671 - 134,169,766 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX134,169,671 - 134,169,766 (-)EnsemblGRCh38hg38GRCh38
GRCh37X133,303,701 - 133,303,796 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X133,131,366 - 133,131,461 (-)NCBINCBI36hg18NCBI36
CeleraX133,690,534 - 133,690,629 (-)NCBI
Cytogenetic MapXq26.2NCBI
HuRefX122,701,740 - 122,701,835 (-)NCBIHuRef
CHM1_1X133,215,397 - 133,215,492 (-)NCBICHM1_1
T2T-CHM13v2.0X132,494,818 - 132,494,913 (-)NCBI
Mir19b-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X51,830,860 - 51,830,943 (-)NCBIGRCm39mm39
GRCm39 EnsemblX51,830,860 - 51,830,943 (-)Ensembl
GRCm38X52,741,983 - 52,742,066 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX52,741,983 - 52,742,066 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X50,095,160 - 50,095,243 (-)NCBIGRCm37mm9NCBIm37
CeleraX40,158,203 - 40,158,286 (-)NCBICelera
Cytogenetic MapXA5NCBI
Mir19b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X132,422,072 - 132,422,167 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX132,422,072 - 132,422,167 (-)Ensembl
Rnor_6.0X140,117,379 - 140,117,474 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX140,117,379 - 140,117,474 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X140,167,226 - 140,167,321 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX131,322,287 - 131,322,382 (-)NCBICelera
Cytogenetic MapXq36NCBI
MIR19B-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X104,895,962 - 104,896,025 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX104,895,962 - 104,896,025 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX91,006,321 - 91,006,384 (-)NCBI
ROS_Cfam_1.0X106,755,718 - 106,755,781 (-)NCBI
UMICH_Zoey_3.1X104,168,894 - 104,168,957 (-)NCBI
UNSW_CanFamBas_1.0X106,034,839 - 106,034,902 (-)NCBI
UU_Cfam_GSD_1.0X105,820,105 - 105,820,168 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000022355
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX110,113,855 - 110,113,934 (-)Ensembl
RefSeq Acc Id: NR_038570
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X110,113,855 - 110,113,934 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000020748 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000022355 ENTREZGENE
miRBase MI0013159 ENTREZGENE
NCBI Gene MIR19B-2 ENTREZGENE
RNAcentral URS000013D17D RNACentral
  URS000066B4C0 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR19B-2  microRNA mir-19b-2    microRNA 19b-2  Symbol and/or name change 5135510 APPROVED