SPIN4 (spindlin family member 4) - Rat Genome Database

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Gene: SPIN4 (spindlin family member 4) Sus scrofa
Analyze
Symbol: SPIN4
Name: spindlin family member 4
RGD ID: 14163207
Description: ENCODES a protein that exhibits methylated histone binding (inferred); INVOLVED IN gamete generation (inferred); regulation of DNA-templated transcription (inferred); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); osteopathia striata with cranial sclerosis (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: spindlin-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX49,976,950 - 49,981,084 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X49,976,956 - 49,981,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IEA)
nucleoplasm  (IBA,IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SPIN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX49,976,950 - 49,981,084 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X49,976,956 - 49,981,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SPIN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X63,347,228 - 63,351,332 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX63,347,228 - 63,351,332 (-)EnsemblGRCh38hg38GRCh38
GRCh37X62,567,107 - 62,571,211 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X62,483,832 - 62,487,943 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX62,913,949 - 62,918,060 (-)NCBICelera
Cytogenetic MapXq11.1NCBI
HuRefX56,393,952 - 56,398,063 (-)NCBIHuRef
CHM1_1X62,459,711 - 62,463,822 (-)NCBICHM1_1
T2T-CHM13v2.0X61,772,497 - 61,776,601 (-)NCBIT2T-CHM13v2.0
Spin4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X94,066,113 - 94,070,288 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX94,066,116 - 94,070,288 (-)EnsemblGRCm39 Ensembl
GRCm38X95,022,507 - 95,026,682 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX95,022,510 - 95,026,682 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X92,217,846 - 92,222,021 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X91,225,229 - 91,229,401 (-)NCBIMGSCv36mm8
CeleraX82,046,345 - 82,050,536 (-)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX41.83NCBI
Spin4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X63,898,338 - 63,902,427 (-)NCBIGRCr8
mRatBN7.2X59,888,728 - 59,892,817 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX59,891,581 - 59,892,330 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX61,359,427 - 61,363,518 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X64,859,949 - 64,864,040 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X62,438,155 - 62,442,244 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X64,217,074 - 64,221,225 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX64,219,933 - 64,220,593 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0X65,118,212 - 65,123,811 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X82,564,580 - 82,565,329 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX60,320,231 - 60,324,382 (-)NCBICelera
Cytogenetic MapXq22NCBI
Spin4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554753,970,481 - 3,971,230 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554753,967,813 - 3,971,725 (-)NCBIChiLan1.0ChiLan1.0
SPIN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X62,898,091 - 63,113,996 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X62,900,023 - 63,117,594 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X52,489,880 - 52,494,902 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X62,502,776 - 62,506,934 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX62,505,610 - 62,506,359 (-)Ensemblpanpan1.1panPan2
SPIN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X48,805,292 - 48,809,546 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX48,808,215 - 48,808,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX39,675,781 - 39,680,076 (+)NCBIDog10K_Boxer_Tasha
Spin4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X53,602,203 - 53,606,366 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366354,368,491 - 4,369,240 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366354,367,956 - 4,369,768 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPIN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X53,601,474 - 53,605,617 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX53,604,335 - 53,605,081 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666083820,332 - 824,461 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spin4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248983,525,469 - 3,526,218 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248983,524,809 - 3,528,954 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SPIN4
2 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system nervous system
High
Medium
Low 4
Below cutoff 1 3

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021080353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000053098   ⟹   ENSSSCP00000033440
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX49,976,950 - 49,981,084 (-)Ensembl
RefSeq Acc Id: XM_021080353   ⟹   XP_020936012
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X49,976,956 - 49,981,312 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020936012   ⟸   XM_021080353
- UniProtKB: A0A286ZPC2 (UniProtKB/TrEMBL),   A0A4X1SFG8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000033440   ⟸   ENSSSCT00000053098


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000036647 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015076555 UniProtKB/TrEMBL
  ENSSSCG00025034577 UniProtKB/TrEMBL
  ENSSSCG00030024144 UniProtKB/TrEMBL
  ENSSSCG00035012276 UniProtKB/TrEMBL
  ENSSSCG00040052061 UniProtKB/TrEMBL
  ENSSSCG00045013209 UniProtKB/TrEMBL
  ENSSSCG00050072907 UniProtKB/TrEMBL
  ENSSSCG00055028888 UniProtKB/TrEMBL
  ENSSSCG00060006603 UniProtKB/TrEMBL
  ENSSSCG00065025386 UniProtKB/TrEMBL
  ENSSSCG00070000363 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000053098 ENTREZGENE
  ENSSSCT00000053098.3 UniProtKB/TrEMBL
  ENSSSCT00015103259.1 UniProtKB/TrEMBL
  ENSSSCT00025047125.1 UniProtKB/TrEMBL
  ENSSSCT00030033548.1 UniProtKB/TrEMBL
  ENSSSCT00035015439.1 UniProtKB/TrEMBL
  ENSSSCT00040070289.1 UniProtKB/TrEMBL
  ENSSSCT00045022474.1 UniProtKB/TrEMBL
  ENSSSCT00050099573.1 UniProtKB/TrEMBL
  ENSSSCT00055057319.1 UniProtKB/TrEMBL
  ENSSSCT00060008395.1 UniProtKB/TrEMBL
  ENSSSCT00065033972.1 UniProtKB/TrEMBL
  ENSSSCT00070000648.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.70 UniProtKB/TrEMBL
InterPro SPIN/Ssty UniProtKB/TrEMBL
  SPIN/Ssty_sf UniProtKB/TrEMBL
NCBI Gene SPIN4 ENTREZGENE
PANTHER PTHR10405 UniProtKB/TrEMBL
  PTHR10405:SF9 UniProtKB/TrEMBL
Pfam Spin-Ssty UniProtKB/TrEMBL
UniProt A0A286ZPC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SFG8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:93408 ENTREZGENE