BTNL2 (butyrophilin like 2) - Rat Genome Database

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Gene: BTNL2 (butyrophilin like 2) Sus scrofa
Analyze
Symbol: BTNL2
Name: butyrophilin like 2
RGD ID: 14162357
Description: ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN negative regulation of T cell receptor signaling pathway (ortholog); positive regulation of interleukin-2 production (ortholog); positive regulation of T cell proliferation (ortholog); ASSOCIATED WITH berylliosis (ortholog); coronary artery disease (ortholog); genetic disease (ortholog); FOUND IN external side of plasma membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: butyrophilin-like 2 (MHC class II associated); butyrophilin-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,790,614 - 24,807,432 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,789,988 - 24,809,920 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,001,473 - 29,021,390 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
BTNL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,790,614 - 24,807,432 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,789,988 - 24,809,920 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,001,473 - 29,021,390 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BTNL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,393,339 - 32,407,181 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,393,339 - 32,407,181 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,361,116 - 32,374,958 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,470,491 - 32,482,878 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,470,490 - 32,482,878NCBI
Celera633,929,258 - 33,941,628 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,116,435 - 32,128,672 (-)NCBIHuRef
CHM1_1632,364,981 - 32,377,368 (-)NCBICHM1_1
T2T-CHM13v2.0632,246,262 - 32,260,103 (-)NCBIT2T-CHM13v2.0
Btnl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,573,763 - 34,588,466 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,573,796 - 34,588,469 (+)EnsemblGRCm39 Ensembl
GRCm381734,354,789 - 34,369,492 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,354,822 - 34,369,495 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,491,767 - 34,506,437 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,962,403 - 33,977,115 (+)NCBIMGSCv36mm8
Celera1737,117,517 - 37,137,992 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Btnl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,492,100 - 4,505,932 (-)NCBIGRCr8
mRatBN7.2204,490,169 - 4,504,002 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,489,517 - 4,503,341 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,254,364 - 5,265,996 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,616,104 - 4,627,736 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,088,388 - 5,099,896 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,140,184 - 4,156,365 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,141,878 - 4,154,978 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,221,727 - 6,236,503 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,613,726 - 4,625,383 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,701,740 - 4,702,792 (+)NCBI
Celera206,093,476 - 6,105,126 (-)NCBICelera
Cytogenetic Map20p12NCBI
Btnl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,083,745 - 1,101,730 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,084,330 - 1,101,751 (-)NCBIChiLan1.0ChiLan1.0
BTNL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,879,850 - 46,942,392 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,844,186 - 42,903,429 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,067,223 - 32,126,032 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,944,694 - 32,950,097 (-)NCBIpanpan1.1PanPan1.1panPan2
BTNL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,085,589 - 2,106,787 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,086,324 - 2,107,124 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,235,540 - 2,256,084 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0122,362,341 - 2,383,324 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl122,362,672 - 2,383,780 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,085,680 - 2,106,664 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,166,791 - 2,187,786 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,240,782 - 2,261,746 (-)NCBIUU_Cfam_GSD_1.0
Btnl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494636,973,660 - 36,993,788 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936727567,656 - 587,784 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936727567,656 - 587,784 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0

Variants

.
Variants in BTNL2
367 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system
High
Medium 5
Low 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000001605   ⟹   ENSSSCP00000001563
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl724,790,614 - 24,807,432 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000072990   ⟹   ENSSSCP00000066618
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl724,793,583 - 24,806,962 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000089511   ⟹   ENSSSCP00000059883
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl724,792,632 - 24,806,962 (-)Ensembl
RefSeq Acc Id: XM_003482157   ⟹   XP_003482205
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1724,789,988 - 24,809,920 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013977699   ⟹   XP_013833153
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1724,789,988 - 24,809,920 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013977700   ⟹   XP_013833154
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1724,789,988 - 24,809,920 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013977701   ⟹   XP_013833155
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1724,789,988 - 24,809,920 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021098499   ⟹   XP_020954158
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1724,789,988 - 24,809,920 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021098500   ⟹   XP_020954159
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1724,789,988 - 24,809,920 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020954158   ⟸   XM_021098499
- UniProtKB: A0A8D1CRN6 (UniProtKB/TrEMBL),   A0A8D0IZ72 (UniProtKB/TrEMBL),   A0A8D1X2I5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020954159   ⟸   XM_021098500
- UniProtKB: A0A8D1CRN6 (UniProtKB/TrEMBL),   A0A8D0IZ72 (UniProtKB/TrEMBL),   A0A8D1X2I5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013833155   ⟸   XM_013977701
- UniProtKB: A0A8D1CRN6 (UniProtKB/TrEMBL),   A0A8D0IZ72 (UniProtKB/TrEMBL),   A0A8D1X2I5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013833153   ⟸   XM_013977699
- UniProtKB: A0A8D1CRN6 (UniProtKB/TrEMBL),   A0A8D0IZ72 (UniProtKB/TrEMBL),   A0A8D1X2I5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013833154   ⟸   XM_013977700
- UniProtKB: A0A8D1CRN6 (UniProtKB/TrEMBL),   A0A8D0IZ72 (UniProtKB/TrEMBL),   A0A8D1X2I5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003482205   ⟸   XM_003482157
- UniProtKB: A0A8D1CRN6 (UniProtKB/TrEMBL),   A0A8D0IZ72 (UniProtKB/TrEMBL),   A0A8D1X2I5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000001563   ⟸   ENSSSCT00000001605
RefSeq Acc Id: ENSSSCP00000059883   ⟸   ENSSSCT00000089511
RefSeq Acc Id: ENSSSCP00000066618   ⟸   ENSSSCT00000072990
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025071 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005019271 UniProtKB/TrEMBL
  ENSSSCG00015020753 UniProtKB/TrEMBL
  ENSSSCG00025012387 UniProtKB/TrEMBL
  ENSSSCG00030025441 UniProtKB/TrEMBL
  ENSSSCG00035029999 UniProtKB/TrEMBL
  ENSSSCG00040067559 UniProtKB/TrEMBL
  ENSSSCG00045012352 UniProtKB/TrEMBL
  ENSSSCG00055007458 UniProtKB/TrEMBL
  ENSSSCG00060078661 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001605 ENTREZGENE
  ENSSSCT00000001605.5 UniProtKB/TrEMBL
  ENSSSCT00000072990.2 UniProtKB/TrEMBL
  ENSSSCT00000089511.2 UniProtKB/TrEMBL
  ENSSSCT00005030380.1 UniProtKB/TrEMBL
  ENSSSCT00005030411.1 UniProtKB/TrEMBL
  ENSSSCT00005030421.1 UniProtKB/TrEMBL
  ENSSSCT00015027404.1 UniProtKB/TrEMBL
  ENSSSCT00015027471.1 UniProtKB/TrEMBL
  ENSSSCT00015027549.1 UniProtKB/TrEMBL
  ENSSSCT00025016371.1 UniProtKB/TrEMBL
  ENSSSCT00025016421.1 UniProtKB/TrEMBL
  ENSSSCT00025016452.1 UniProtKB/TrEMBL
  ENSSSCT00030035524.1 UniProtKB/TrEMBL
  ENSSSCT00030035531.1 UniProtKB/TrEMBL
  ENSSSCT00035039753.1 UniProtKB/TrEMBL
  ENSSSCT00035039764.1 UniProtKB/TrEMBL
  ENSSSCT00040092681.1 UniProtKB/TrEMBL
  ENSSSCT00045021013.1 UniProtKB/TrEMBL
  ENSSSCT00045021043.1 UniProtKB/TrEMBL
  ENSSSCT00045021068.1 UniProtKB/TrEMBL
  ENSSSCT00055014591.1 UniProtKB/TrEMBL
  ENSSSCT00060108761.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
KEGG Report ssc:100158014 UniProtKB/TrEMBL
NCBI Gene BTNL2 ENTREZGENE
PANTHER BTNL2-RELATED UniProtKB/TrEMBL
  BUTYROPHILIN UniProtKB/TrEMBL
  BUTYROPHILIN SUBFAMILY 1 MEMBER A1 UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A5G2Q760_PIG UniProtKB/TrEMBL
  A0A5G2QNZ9_PIG UniProtKB/TrEMBL
  A0A8D0ITA7_PIG UniProtKB/TrEMBL
  A0A8D0IZ72 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MYS6_PIG UniProtKB/TrEMBL
  A0A8D0N0V1_PIG UniProtKB/TrEMBL
  A0A8D0N0W9_PIG UniProtKB/TrEMBL
  A0A8D0W4M1_PIG UniProtKB/TrEMBL
  A0A8D1CRN6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1H8T1_PIG UniProtKB/TrEMBL
  A0A8D1HCQ5_PIG UniProtKB/TrEMBL
  A0A8D1X2I5 ENTREZGENE, UniProtKB/TrEMBL
  A5D9J9_PIG UniProtKB/TrEMBL
  A5D9K0_PIG UniProtKB/TrEMBL
  F1RQ42_PIG UniProtKB/TrEMBL
UniProt Secondary F1RQ43 UniProtKB/TrEMBL
VGNC ID VGNC:85916 ENTREZGENE