EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit) - Rat Genome Database

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Gene: EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit) Sus scrofa
Analyze
Symbol: EZH1
Name: enhancer of zeste 1 polycomb repressive complex 2 subunit
RGD ID: 14162175
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); histone binding (ortholog); INVOLVED IN facultative heterochromatin formation (ortholog); hepatocyte homeostasis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN chromosome, telomeric region (ortholog); heterochromatin (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: enhancer of zeste homolog 1; histone-lysine N-methyltransferase EZH1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,115,297 - 20,141,749 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,107,744 - 20,139,764 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,304,800 - 20,338,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EZH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,115,297 - 20,141,749 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,107,744 - 20,139,764 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,304,800 - 20,338,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EZH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,700,275 - 42,745,040 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,700,275 - 42,745,049 (-)EnsemblGRCh38hg38GRCh38
GRCh371740,852,293 - 40,897,058 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,105,819 - 38,150,574 (-)NCBINCBI36Build 36hg18NCBI36
Build 341738,105,819 - 38,150,574NCBI
Celera1737,507,762 - 37,552,422 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1736,617,368 - 36,662,170 (-)NCBIHuRef
CHM1_11741,087,908 - 41,132,634 (-)NCBICHM1_1
T2T-CHM13v2.01743,557,412 - 43,602,180 (-)NCBIT2T-CHM13v2.0
Ezh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,081,941 - 101,117,268 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,081,941 - 101,117,289 (-)EnsemblGRCm39 Ensembl
GRCm3811101,191,115 - 101,226,463 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,191,115 - 101,226,463 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,052,429 - 101,087,764 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611101,007,206 - 101,044,038 (-)NCBIMGSCv36mm8
Celera11112,487,231 - 112,522,681 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1164.37NCBI
Ezh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,626,307 - 86,662,257 (-)NCBIGRCr8
mRatBN7.21086,126,023 - 86,162,001 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,126,015 - 86,161,921 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,162,463 - 91,188,804 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,641,259 - 90,667,579 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,034,424 - 86,060,744 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,104,026 - 89,139,978 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,104,027 - 89,130,339 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,902,522 - 88,938,413 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,211,249 - 90,237,563 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11090,227,546 - 90,252,203 (-)NCBI
Celera1084,843,423 - 84,869,785 (-)NCBICelera
Cytogenetic Map10q31NCBI
Ezh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,548,858 - 16,564,310 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,548,898 - 16,563,449 (-)NCBIChiLan1.0ChiLan1.0
EZH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,240,711 - 22,285,877 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,130,797 - 24,175,862 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,572,868 - 14,618,012 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,814,061 - 14,842,295 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1714,814,054 - 14,842,295 (+)Ensemblpanpan1.1panPan2
EZH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,271,729 - 20,292,918 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,264,552 - 20,290,712 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,724,769 - 19,754,876 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,981,842 - 21,011,945 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,981,878 - 21,011,945 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1919,767,995 - 19,797,890 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,032,956 - 20,063,052 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,136,953 - 20,167,063 (+)NCBIUU_Cfam_GSD_1.0
Ezh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,609,211 - 19,644,761 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,428,677 - 17,465,877 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,430,383 - 17,465,889 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EZH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,544,483 - 63,592,651 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,558,551 - 63,587,501 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,337,734 - 34,385,777 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ezh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247951,454,361 - 1,470,079 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EZH1
1024 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 4 3 5 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000018921   ⟹   ENSSSCP00000018416
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1220,115,297 - 20,141,749 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000072319   ⟹   ENSSSCP00000072774
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1220,118,863 - 20,141,749 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000085050   ⟹   ENSSSCP00000067879
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1220,115,297 - 20,141,749 (+)Ensembl
RefSeq Acc Id: NM_001243206   ⟹   NP_001230135
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11220,107,744 - 20,139,764 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001230135   ⟸   NM_001243206
- UniProtKB: A0A8D0Y904 (UniProtKB/TrEMBL),   A0A8D0IP85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000067879   ⟸   ENSSSCT00000085050
RefSeq Acc Id: ENSSSCP00000018416   ⟸   ENSSSCT00000018921
RefSeq Acc Id: ENSSSCP00000072774   ⟸   ENSSSCT00000072319
Protein Domains
CXC   SET


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017382 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005011269 UniProtKB/TrEMBL
  ENSSSCG00015071646 UniProtKB/TrEMBL
  ENSSSCG00025056773 UniProtKB/TrEMBL
  ENSSSCG00030071131 UniProtKB/TrEMBL
  ENSSSCG00035016090 UniProtKB/TrEMBL
  ENSSSCG00040027555 UniProtKB/TrEMBL
  ENSSSCG00050062509 UniProtKB/TrEMBL
  ENSSSCG00055026372 UniProtKB/TrEMBL
  ENSSSCG00060044581 UniProtKB/TrEMBL
  ENSSSCG00065003487 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018921 ENTREZGENE
  ENSSSCT00000018921.5 UniProtKB/TrEMBL
  ENSSSCT00000072319.2 UniProtKB/TrEMBL
  ENSSSCT00000085050.1 UniProtKB/TrEMBL
  ENSSSCT00005019169.1 UniProtKB/TrEMBL
  ENSSSCT00015098074.1 UniProtKB/TrEMBL
  ENSSSCT00015098320.1 UniProtKB/TrEMBL
  ENSSSCT00015098511.1 UniProtKB/TrEMBL
  ENSSSCT00015098707.1 UniProtKB/TrEMBL
  ENSSSCT00025077788.1 UniProtKB/TrEMBL
  ENSSSCT00025078142.1 UniProtKB/TrEMBL
  ENSSSCT00025078464.1 UniProtKB/TrEMBL
  ENSSSCT00030099521.1 UniProtKB/TrEMBL
  ENSSSCT00030099562.1 UniProtKB/TrEMBL
  ENSSSCT00030099606.1 UniProtKB/TrEMBL
  ENSSSCT00035020543.1 UniProtKB/TrEMBL
  ENSSSCT00035020561.1 UniProtKB/TrEMBL
  ENSSSCT00035020568.1 UniProtKB/TrEMBL
  ENSSSCT00040036989.1 UniProtKB/TrEMBL
  ENSSSCT00040037416.1 UniProtKB/TrEMBL
  ENSSSCT00040037583.1 UniProtKB/TrEMBL
  ENSSSCT00050085157.1 UniProtKB/TrEMBL
  ENSSSCT00050085160.1 UniProtKB/TrEMBL
  ENSSSCT00050085162.1 UniProtKB/TrEMBL
  ENSSSCT00055052222.1 UniProtKB/TrEMBL
  ENSSSCT00055052410.1 UniProtKB/TrEMBL
  ENSSSCT00055052510.1 UniProtKB/TrEMBL
  ENSSSCT00060060469.1 UniProtKB/TrEMBL
  ENSSSCT00060060481.1 UniProtKB/TrEMBL
  ENSSSCT00060060485.1 UniProtKB/TrEMBL
  ENSSSCT00065004750.1 UniProtKB/TrEMBL
  ENSSSCT00065004753.1 UniProtKB/TrEMBL
  ENSSSCT00065004757.1 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
InterPro CXC_dom UniProtKB/TrEMBL
  EZH1/2-like UniProtKB/TrEMBL
  EZH1/2_MCSS UniProtKB/TrEMBL
  EZH1/EZH2 UniProtKB/TrEMBL
  EZH1_SET UniProtKB/TrEMBL
  PRC2_HTH_1 UniProtKB/TrEMBL
  Pre-SET_CXC UniProtKB/TrEMBL
  SANT/Myb UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  Tesmin/TSO1-like_CXC UniProtKB/TrEMBL
KEGG Report ssc:100518394 UniProtKB/TrEMBL
NCBI Gene EZH1 ENTREZGENE
PANTHER PTHR45747 UniProtKB/TrEMBL
  PTHR45747:SF1 UniProtKB/TrEMBL
Pfam Ezh2_MCSS UniProtKB/TrEMBL
  EZH2_WD-Binding UniProtKB/TrEMBL
  PRC2_HTH_1 UniProtKB/TrEMBL
  preSET_CXC UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PROSITE CXC UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART CXC UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP SSF82199 UniProtKB/TrEMBL
UniProt A0A5G2QUQ3_PIG UniProtKB/TrEMBL
  A0A5G2R8X2_PIG UniProtKB/TrEMBL
  A0A8D0IP85 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Q484_PIG UniProtKB/TrEMBL
  A0A8D0Y3H8_PIG UniProtKB/TrEMBL
  A0A8D0Y904 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RXA0_PIG UniProtKB/TrEMBL
  A0A8D1X8Q1_PIG UniProtKB/TrEMBL
  F1S1G9_PIG UniProtKB/TrEMBL
VGNC ID VGNC:87854 ENTREZGENE