ACSM5 (acyl-CoA synthetase medium chain family member 5) - Rat Genome Database

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Gene: ACSM5 (acyl-CoA synthetase medium chain family member 5) Sus scrofa
Analyze
Symbol: ACSM5
Name: acyl-CoA synthetase medium chain family member 5
RGD ID: 14158024
Description: ENCODES a protein that exhibits acid-thiol ligase activity (inferred); CoA-ligase activity (inferred); fatty acid ligase activity (inferred); INVOLVED IN acyl-CoA metabolic process (inferred); fatty acid biosynthetic process (inferred); lipid metabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN mitochondrial matrix (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-coenzyme A synthetase ACSM5, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl325,393,190 - 25,422,476 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1325,393,121 - 25,422,551 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2326,172,262 - 26,260,399 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
ACSM5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl325,393,190 - 25,422,476 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1325,393,121 - 25,422,551 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2326,172,262 - 26,260,399 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACSM5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381620,409,534 - 20,441,336 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1620,409,534 - 20,441,336 (+)EnsemblGRCh38hg38GRCh38
GRCh371620,420,856 - 20,452,658 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361620,328,357 - 20,359,791 (+)NCBINCBI36Build 36hg18NCBI36
Celera1619,570,305 - 19,620,803 (+)NCBICelera
Cytogenetic Map16p12.3NCBI
HuRef1618,957,265 - 18,988,605 (+)NCBIHuRef
CHM1_11620,509,049 - 20,540,458 (+)NCBICHM1_1
T2T-CHM13v2.01620,340,542 - 20,372,354 (+)NCBIT2T-CHM13v2.0
Acsm5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397119,125,354 - 119,142,583 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7119,118,686 - 119,144,774 (+)EnsemblGRCm39 Ensembl
GRCm387119,526,131 - 119,543,360 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7119,519,463 - 119,545,551 (+)EnsemblGRCm38mm10GRCm38
MGSCv377126,669,779 - 126,686,874 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367119,317,390 - 119,334,942 (+)NCBIMGSCv36mm8
Celera7119,443,888 - 119,461,026 (+)NCBICelera
Cytogenetic Map7F2NCBI
cM Map763.94NCBI
Acsm5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81183,302,241 - 183,328,175 (+)NCBIGRCr8
mRatBN7.21173,870,873 - 173,896,838 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1173,863,041 - 173,898,588 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1182,182,608 - 182,209,756 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01189,368,714 - 189,395,865 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,103,934 - 182,131,081 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,240,955 - 189,270,422 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,233,141 - 189,272,172 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01196,182,194 - 196,208,230 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41177,785,186 - 177,808,572 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11177,924,431 - 177,947,815 (+)NCBI
Celera1171,623,897 - 171,653,739 (+)NCBICelera
Cytogenetic Map1q35NCBI
Acsm5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554424,046,714 - 4,076,044 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554424,047,059 - 4,075,158 (+)NCBIChiLan1.0ChiLan1.0
ACSM5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21821,674,412 - 21,710,286 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11626,194,536 - 26,225,903 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01617,870,259 - 17,901,984 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11620,505,983 - 20,764,275 (+)NCBIpanpan1.1PanPan1.1panPan2
ACSM5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1624,907,766 - 24,943,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl624,907,236 - 24,940,862 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,132,530 - 39,168,614 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0625,061,811 - 25,097,894 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl625,061,290 - 25,094,664 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1624,862,666 - 24,898,749 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0624,757,794 - 24,793,879 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0625,145,748 - 25,181,821 (-)NCBIUU_Cfam_GSD_1.0
Acsm5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344117,794,121 - 117,818,115 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365015,891,900 - 5,916,031 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365015,891,989 - 5,915,929 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACSM5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1518,695,695 - 18,727,551 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl518,698,330 - 18,726,765 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606811,178,507 - 11,209,583 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acsm5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247823,709,020 - 3,731,601 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247823,708,941 - 3,729,359 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ACSM5
1162 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 2 4 2 5 1 16 2 2 3
Below cutoff 5 1 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000027749   ⟹   ENSSSCP00000020240
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl325,393,190 - 25,422,476 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000041222   ⟹   ENSSSCP00000039901
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl325,393,194 - 25,422,431 (-)Ensembl
RefSeq Acc Id: XM_003124563   ⟹   XP_003124611
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1325,393,121 - 25,422,551 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005662100   ⟹   XP_005662157
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1325,393,694 - 25,422,498 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005662101   ⟹   XP_005662158
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1325,393,694 - 25,422,498 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021086523   ⟹   XP_020942182
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1325,393,121 - 25,422,509 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003124611   ⟸   XM_003124563
- Peptide Label: isoform X1
- UniProtKB: I3L882 (UniProtKB/TrEMBL),   A0A8D2A1H2 (UniProtKB/TrEMBL),   A0A8D0M8F9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020942182   ⟸   XM_021086523
- Peptide Label: isoform X2
- UniProtKB: A0A287A7W3 (UniProtKB/TrEMBL),   A0A8D0YWD2 (UniProtKB/TrEMBL),   A0A8D0TSL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005662158   ⟸   XM_005662101
- Peptide Label: isoform X3
- UniProtKB: A0A8D1QKL8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005662157   ⟸   XM_005662100
- Peptide Label: isoform X3
- UniProtKB: A0A8D1QKL8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000039901   ⟸   ENSSSCT00000041222
RefSeq Acc Id: ENSSSCP00000020240   ⟸   ENSSSCT00000027749
Protein Domains
AMP-binding enzyme C-terminal   AMP-dependent synthetase/ligase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000026453 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005045926 UniProtKB/TrEMBL
  ENSSSCG00030018594 UniProtKB/TrEMBL
  ENSSSCG00035017815 UniProtKB/TrEMBL
  ENSSSCG00055013146 UniProtKB/TrEMBL
  ENSSSCG00060063276 UniProtKB/TrEMBL
  ENSSSCG00065073417 UniProtKB/TrEMBL
  ENSSSCG00070024385 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000027749 ENTREZGENE
  ENSSSCT00000027749.4 UniProtKB/TrEMBL
  ENSSSCT00000041222 ENTREZGENE
  ENSSSCT00000041222.3 UniProtKB/TrEMBL
  ENSSSCT00005074335.1 UniProtKB/TrEMBL
  ENSSSCT00005074337.1 UniProtKB/TrEMBL
  ENSSSCT00030025672.1 UniProtKB/TrEMBL
  ENSSSCT00030025678.1 UniProtKB/TrEMBL
  ENSSSCT00030025685.1 UniProtKB/TrEMBL
  ENSSSCT00035022939.1 UniProtKB/TrEMBL
  ENSSSCT00035022941.1 UniProtKB/TrEMBL
  ENSSSCT00055025904.1 UniProtKB/TrEMBL
  ENSSSCT00060086307.1 UniProtKB/TrEMBL
  ENSSSCT00060086328.1 UniProtKB/TrEMBL
  ENSSSCT00060086338.1 UniProtKB/TrEMBL
  ENSSSCT00065101054.1 UniProtKB/TrEMBL
  ENSSSCT00065101072.1 UniProtKB/TrEMBL
  ENSSSCT00070048717.1 UniProtKB/TrEMBL
  ENSSSCT00070048724.1 UniProtKB/TrEMBL
  ENSSSCT00070048728.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.300.30 UniProtKB/TrEMBL
  3.40.50.12780 UniProtKB/TrEMBL
InterPro AMP-bd_C UniProtKB/TrEMBL
  AMP-bd_C_sf UniProtKB/TrEMBL
  AMP-binding_CS UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  AMP-dep_Synthh-like_sf UniProtKB/TrEMBL
KEGG Report ssc:100511318 UniProtKB/TrEMBL
NCBI Gene ACSM5 ENTREZGENE
PANTHER ACYL-COENZYME A SYNTHETASE UniProtKB/TrEMBL
  ACYL-COENZYME A SYNTHETASE ACSM5, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam AMP-binding UniProtKB/TrEMBL
  AMP-binding_C UniProtKB/TrEMBL
PROSITE AMP_BINDING UniProtKB/TrEMBL
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/TrEMBL
UniProt A0A287A7W3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VH32_PIG UniProtKB/TrEMBL
  A0A4X1VH42_PIG UniProtKB/TrEMBL
  A0A4X1VI59_PIG UniProtKB/TrEMBL
  A0A8D0M8F9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TSL4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0VU48_PIG UniProtKB/TrEMBL
  A0A8D0VWT0_PIG UniProtKB/TrEMBL
  A0A8D0YWD2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1QKL8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WCL8_PIG UniProtKB/TrEMBL
  A0A8D2A1H2 ENTREZGENE, UniProtKB/TrEMBL
  I3L882 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:85036 ENTREZGENE