TFB2M (transcription factor B2, mitochondrial) - Rat Genome Database

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Gene: TFB2M (transcription factor B2, mitochondrial) Sus scrofa
Analyze
Symbol: TFB2M
Name: transcription factor B2, mitochondrial
RGD ID: 14154264
Description: ENCODES a protein that exhibits methyltransferase activity (inferred); mitochondrial transcription factor activity (inferred); RNA binding (inferred); INVOLVED IN methylation (inferred); mitochondrial transcription (inferred); rRNA methylation (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 54 (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrial nucleoid (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dimethyladenosine transferase 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1019,028,820 - 19,046,327 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11019,028,813 - 19,046,343 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21021,380,800 - 21,391,917 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TFB2M
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1019,028,820 - 19,046,327 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11019,028,813 - 19,046,343 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21021,380,800 - 21,391,917 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TFB2M
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381246,540,561 - 246,566,261 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1246,540,561 - 246,566,261 (-)EnsemblGRCh38hg38GRCh38
GRCh371246,703,863 - 246,729,563 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361244,770,489 - 244,796,186 (-)NCBINCBI36Build 36hg18NCBI36
Build 341243,029,908 - 243,055,604NCBI
Celera1219,991,213 - 220,016,913 (-)NCBICelera
Cytogenetic Map1q44NCBI
HuRef1217,089,659 - 217,115,356 (-)NCBIHuRef
CHM1_11247,976,165 - 248,001,862 (-)NCBICHM1_1
T2T-CHM13v2.01245,961,432 - 245,987,151 (-)NCBIT2T-CHM13v2.0
Tfb2m
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391179,355,617 - 179,373,870 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1179,355,620 - 179,373,832 (-)EnsemblGRCm39 Ensembl
GRCm381179,528,052 - 179,546,305 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1179,528,055 - 179,546,267 (-)EnsemblGRCm38mm10GRCm38
MGSCv371181,458,187 - 181,476,398 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361181,364,731 - 181,382,942 (-)NCBIMGSCv36mm8
Celera1186,598,996 - 186,617,245 (-)NCBICelera
Cytogenetic Map1H4NCBI
cM Map183.56NCBI
Tfb2m
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81393,810,859 - 93,828,678 (-)NCBIGRCr8
mRatBN7.21391,278,889 - 91,296,709 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1391,278,898 - 91,296,657 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1393,784,087 - 93,801,822 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01395,184,250 - 95,201,981 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01392,358,929 - 92,376,664 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01397,820,493 - 97,838,275 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1397,613,991 - 97,628,059 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1397,820,493 - 97,838,228 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013102,830,291 - 102,848,026 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.013102,630,835 - 102,643,959 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41395,228,520 - 95,246,255 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11395,417,455 - 95,435,191 (-)NCBI
Celera1390,831,066 - 90,847,804 (-)NCBICelera
Cytogenetic Map13q26NCBI
Tfb2m
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554069,421,957 - 9,441,091 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554069,424,329 - 9,441,212 (-)NCBIChiLan1.0ChiLan1.0
TFB2M
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212,566,012 - 2,591,941 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112,782,783 - 2,808,906 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01222,157,251 - 222,184,186 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11227,512,367 - 227,538,060 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1227,512,367 - 227,538,060 (-)Ensemblpanpan1.1panPan2
TFB2M
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1737,259,671 - 37,278,397 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl737,250,601 - 37,278,366 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha736,742,133 - 36,760,850 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0737,091,933 - 37,110,662 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl737,085,571 - 37,110,687 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1736,932,190 - 36,950,900 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0736,940,202 - 36,958,896 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0737,209,120 - 37,227,834 (-)NCBIUU_Cfam_GSD_1.0
Tfb2m
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934450,226,674 - 50,249,990 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365264,497,507 - 4,520,048 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365264,497,396 - 4,520,650 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFB2M
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12583,564,405 - 83,591,980 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2583,564,432 - 83,591,930 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605585,842,481 - 85,869,767 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfb2m
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477113,115,227 - 13,132,841 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TFB2M
415 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000032587   ⟹   ENSSSCP00000019262
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1019,028,820 - 19,046,327 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000037887   ⟹   ENSSSCP00000055985
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1019,028,821 - 19,046,307 (-)Ensembl
RefSeq Acc Id: XM_021064472   ⟹   XP_020920131
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11019,028,813 - 19,046,343 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021064473   ⟹   XP_020920132
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11019,028,813 - 19,046,338 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020920131   ⟸   XM_021064472
- Peptide Label: isoform X1
- UniProtKB: I3L5G3 (UniProtKB/TrEMBL),   A0A480RRY5 (UniProtKB/TrEMBL),   A0A480X542 (UniProtKB/TrEMBL),   A0A4X1T1R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020920132   ⟸   XM_021064473
- Peptide Label: isoform X2
- UniProtKB: A0A287BHB8 (UniProtKB/TrEMBL),   A0A8D1JDZ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000019262   ⟸   ENSSSCT00000032587
RefSeq Acc Id: ENSSSCP00000055985   ⟸   ENSSSCT00000037887
Protein Domains
Ribosomal RNA adenine methylase transferase N-


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000023775 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005005110 UniProtKB/TrEMBL
  ENSSSCG00025011726 UniProtKB/TrEMBL
  ENSSSCG00030028637 UniProtKB/TrEMBL
  ENSSSCG00035023721 UniProtKB/TrEMBL
  ENSSSCG00040058075 UniProtKB/TrEMBL
  ENSSSCG00045035559 UniProtKB/TrEMBL
  ENSSSCG00050016552 UniProtKB/TrEMBL
  ENSSSCG00055023291 UniProtKB/TrEMBL
  ENSSSCG00060024556 UniProtKB/TrEMBL
  ENSSSCG00065067844 UniProtKB/TrEMBL
  ENSSSCG00070005549 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000032587 ENTREZGENE
  ENSSSCT00000032587.4 UniProtKB/TrEMBL
  ENSSSCT00000037887 ENTREZGENE
  ENSSSCT00000037887.3 UniProtKB/TrEMBL
  ENSSSCT00005007607.1 UniProtKB/TrEMBL
  ENSSSCT00025015697.1 UniProtKB/TrEMBL
  ENSSSCT00025015732.1 UniProtKB/TrEMBL
  ENSSSCT00030040015.1 UniProtKB/TrEMBL
  ENSSSCT00030040045.1 UniProtKB/TrEMBL
  ENSSSCT00035031115.1 UniProtKB/TrEMBL
  ENSSSCT00035031121.1 UniProtKB/TrEMBL
  ENSSSCT00035031124.1 UniProtKB/TrEMBL
  ENSSSCT00040078771.1 UniProtKB/TrEMBL
  ENSSSCT00040078899.1 UniProtKB/TrEMBL
  ENSSSCT00040079019.1 UniProtKB/TrEMBL
  ENSSSCT00045061032.1 UniProtKB/TrEMBL
  ENSSSCT00045061113.1 UniProtKB/TrEMBL
  ENSSSCT00045061191.1 UniProtKB/TrEMBL
  ENSSSCT00050022568.1 UniProtKB/TrEMBL
  ENSSSCT00050022574.1 UniProtKB/TrEMBL
  ENSSSCT00055045833.1 UniProtKB/TrEMBL
  ENSSSCT00055045947.1 UniProtKB/TrEMBL
  ENSSSCT00060033290.1 UniProtKB/TrEMBL
  ENSSSCT00060033293.1 UniProtKB/TrEMBL
  ENSSSCT00065093134.1 UniProtKB/TrEMBL
  ENSSSCT00065093140.1 UniProtKB/TrEMBL
  ENSSSCT00070010496.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro KsgA/Erm UniProtKB/TrEMBL
  rRNA_Ade_methylase_Trfase_N UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene TFB2M ENTREZGENE
PANTHER PTHR11727 UniProtKB/TrEMBL
  PTHR11727:SF13 UniProtKB/TrEMBL
Pfam RrnaAD UniProtKB/TrEMBL
PIRSF MtTFB2 UniProtKB/TrEMBL
PROSITE SAM_RNA_A_N6_MT UniProtKB/TrEMBL
SMART rADc UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A287BHB8 ENTREZGENE, UniProtKB/TrEMBL
  A0A480RRY5 ENTREZGENE, UniProtKB/TrEMBL
  A0A480X542 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1T1R2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WAK9_PIG UniProtKB/TrEMBL
  A0A8D1C4V9_PIG UniProtKB/TrEMBL
  A0A8D1FAT5_PIG UniProtKB/TrEMBL
  A0A8D1JDV1_PIG UniProtKB/TrEMBL
  A0A8D1JDZ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1LK07_PIG UniProtKB/TrEMBL
  I3L5G3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:95887 ENTREZGENE