SOAT2 (sterol O-acyltransferase 2) - Rat Genome Database

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Gene: SOAT2 (sterol O-acyltransferase 2) Sus scrofa
Analyze
Symbol: SOAT2
Name: sterol O-acyltransferase 2
RGD ID: 14153067
Description: ENCODES a protein that exhibits sterol O-acyltransferase activity (ortholog); INVOLVED IN cholesterol metabolic process (ortholog); cholesterol storage (ortholog); response to nutrient (ortholog); PARTICIPATES IN kidney failure pathway; ASSOCIATED WITH arteriosclerosis (ortholog); celiac disease (ortholog); cholelithiasis (ortholog); FOUND IN brush border (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,358,673 - 18,371,264 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,358,941 - 18,371,262 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,773,838 - 18,786,099 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SOAT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,358,673 - 18,371,264 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,358,941 - 18,371,262 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,773,838 - 18,786,099 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SOAT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,103,486 - 53,124,535 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,103,486 - 53,124,535 (+)EnsemblGRCh38hg38GRCh38
GRCh371253,497,270 - 53,518,319 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,783,541 - 51,804,590 (+)NCBINCBI36Build 36hg18NCBI36
Build 341251,783,581 - 51,804,589NCBI
Celera1253,145,169 - 53,166,217 (+)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,540,306 - 50,561,441 (+)NCBIHuRef
CHM1_11253,463,699 - 53,484,782 (+)NCBICHM1_1
T2T-CHM13v2.01253,067,863 - 53,088,913 (+)NCBIT2T-CHM13v2.0
Soat2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,058,853 - 102,071,871 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,058,961 - 102,071,904 (+)EnsemblGRCm39 Ensembl
GRCm3815102,150,415 - 102,163,469 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,150,526 - 102,163,469 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715101,981,006 - 101,993,867 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615101,978,609 - 101,991,470 (+)NCBIMGSCv36mm8
Celera15104,305,508 - 104,318,364 (+)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.33NCBI
Soat2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,160,424 - 135,173,521 (+)NCBIGRCr8
mRatBN7.27133,281,818 - 133,294,915 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,281,818 - 133,294,915 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,043,192 - 135,056,256 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,272,559 - 137,285,623 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,257,195 - 137,270,297 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,754,892 - 143,767,989 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,754,892 - 143,767,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,552,394 - 141,565,491 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,890,902 - 140,903,999 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17140,967,338 - 140,980,436 (+)NCBI
Celera7129,716,600 - 129,729,697 (+)NCBICelera
Cytogenetic Map7q36NCBI
Soat2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458382,892 - 394,749 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458383,123 - 394,003 (+)NCBIChiLan1.0ChiLan1.0
SOAT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21041,063,981 - 41,085,825 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11241,060,746 - 41,082,590 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,632,018 - 35,653,227 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,413,954 - 36,434,074 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,413,954 - 36,434,074 (-)Ensemblpanpan1.1panPan2
SOAT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,053,063 - 2,062,773 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl272,053,067 - 2,062,329 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,186,356 - 44,196,074 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0272,057,164 - 2,066,887 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl272,057,174 - 2,066,374 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1272,074,438 - 2,083,937 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,060,773 - 2,070,480 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,585,437 - 44,595,161 (+)NCBIUU_Cfam_GSD_1.0
Soat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,733,617 - 62,745,065 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,420,804 - 10,430,881 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,420,847 - 10,430,813 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOAT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,214,295 - 49,228,268 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,215,034 - 49,228,244 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037196,837,935 - 196,852,282 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Soat2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,160,203 - 1,170,935 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,160,275 - 1,170,249 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SOAT2
323 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system musculoskeletal system nervous system reproductive system respiratory system
High
Medium
Low 8
Below cutoff 2 1 1 1 8 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000000279   ⟹   ENSSSCP00000000275
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl518,358,673 - 18,371,264 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000043738   ⟹   ENSSSCP00000040905
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl518,359,058 - 18,371,258 (+)Ensembl
RefSeq Acc Id: XM_003126184   ⟹   XP_003126232
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1518,359,018 - 18,371,262 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021091697   ⟹   XP_020947356
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1518,358,941 - 18,371,262 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020947356   ⟸   XM_021091697
- Peptide Label: isoform X1
- UniProtKB: A0A4X1WBH7 (UniProtKB/TrEMBL),   A0A8D0SC62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003126232   ⟸   XM_003126184
- Peptide Label: isoform X2
- UniProtKB: A0A8D1YHU4 (UniProtKB/TrEMBL),   F1SGE4 (UniProtKB/TrEMBL),   A0A4X1WBH7 (UniProtKB/TrEMBL),   A0A8D0SC62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000040905   ⟸   ENSSSCT00000043738
RefSeq Acc Id: ENSSSCP00000000275   ⟸   ENSSSCT00000000279


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000260 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005004907 UniProtKB/TrEMBL
  ENSSSCG00015064967 UniProtKB/TrEMBL
  ENSSSCG00025050910 UniProtKB/TrEMBL
  ENSSSCG00030028011 UniProtKB/TrEMBL
  ENSSSCG00035032541 UniProtKB/TrEMBL
  ENSSSCG00040068091 UniProtKB/TrEMBL
  ENSSSCG00045002623 UniProtKB/TrEMBL
  ENSSSCG00055030601 UniProtKB/TrEMBL
  ENSSSCG00060051086 UniProtKB/TrEMBL
  ENSSSCG00065036680 UniProtKB/TrEMBL
  ENSSSCG00070030231 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000279 ENTREZGENE
  ENSSSCT00000000279.3 UniProtKB/TrEMBL
  ENSSSCT00005007718.1 UniProtKB/TrEMBL
  ENSSSCT00015087085.1 UniProtKB/TrEMBL
  ENSSSCT00015087368.1 UniProtKB/TrEMBL
  ENSSSCT00025069536.1 UniProtKB/TrEMBL
  ENSSSCT00025069754.1 UniProtKB/TrEMBL
  ENSSSCT00030039170.1 UniProtKB/TrEMBL
  ENSSSCT00030039195.1 UniProtKB/TrEMBL
  ENSSSCT00035043107.1 UniProtKB/TrEMBL
  ENSSSCT00035043123.1 UniProtKB/TrEMBL
  ENSSSCT00040093242.1 UniProtKB/TrEMBL
  ENSSSCT00040093446.1 UniProtKB/TrEMBL
  ENSSSCT00045004129.1 UniProtKB/TrEMBL
  ENSSSCT00045004177.1 UniProtKB/TrEMBL
  ENSSSCT00055061016.1 UniProtKB/TrEMBL
  ENSSSCT00060069527.1 UniProtKB/TrEMBL
  ENSSSCT00060069536.1 UniProtKB/TrEMBL
  ENSSSCT00065049989.1 UniProtKB/TrEMBL
  ENSSSCT00065050012.1 UniProtKB/TrEMBL
  ENSSSCT00070060833.1 UniProtKB/TrEMBL
InterPro MBOAT_fam UniProtKB/TrEMBL
  Oat_ACAT_DAG_ARE UniProtKB/TrEMBL
  Sterol_acyltranf_meta UniProtKB/TrEMBL
NCBI Gene SOAT2 ENTREZGENE
PANTHER PTHR10408 UniProtKB/TrEMBL
  STEROL O-ACYLTRANSFERASE 2 UniProtKB/TrEMBL
Pfam MBOAT UniProtKB/TrEMBL
PIRSF Oat_ACAT_DAG_ARE UniProtKB/TrEMBL
  Sterol_acyltranf_ACAT UniProtKB/TrEMBL
UniProt A0A4X1WBH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0PT30_PIG UniProtKB/TrEMBL
  A0A8D0SC62 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0W9N2_PIG UniProtKB/TrEMBL
  A0A8D0WBA7_PIG UniProtKB/TrEMBL
  A0A8D0ZEN3_PIG UniProtKB/TrEMBL
  A0A8D1FQG1_PIG UniProtKB/TrEMBL
  A0A8D1YHU4 ENTREZGENE, UniProtKB/TrEMBL
  F1SGE4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:93328 ENTREZGENE