ARL4A (ADP ribosylation factor like GTPase 4A) - Rat Genome Database

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Gene: ARL4A (ADP ribosylation factor like GTPase 4A) Sus scrofa
Analyze
Symbol: ARL4A
Name: ADP ribosylation factor like GTPase 4A
RGD ID: 14152482
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); INVOLVED IN brown fat cell differentiation (ortholog); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosylation factor-like protein 4A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl982,225,272 - 82,231,900 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1982,224,985 - 82,228,951 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2990,366,105 - 90,368,735 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleolus  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)
plasma membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARL4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl982,225,272 - 82,231,900 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1982,224,985 - 82,228,951 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2990,366,105 - 90,368,735 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARL4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38712,686,903 - 12,690,958 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl712,686,856 - 12,690,958 (+)EnsemblGRCh38hg38GRCh38
GRCh37712,726,528 - 12,730,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36712,693,006 - 12,697,084 (+)NCBINCBI36Build 36hg18NCBI36
Celera712,704,156 - 12,708,234 (+)NCBICelera
Cytogenetic Map7p21.3NCBI
HuRef712,607,443 - 12,611,550 (+)NCBIHuRef
CHM1_1712,726,522 - 12,730,629 (+)NCBICHM1_1
T2T-CHM13v2.0712,817,976 - 12,822,031 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2712,777,588 - 12,781,695 (+)NCBI
Arl4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391240,083,290 - 40,087,986 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1240,055,446 - 40,088,024 (-)EnsemblGRCm39 Ensembl
GRCm381240,033,291 - 40,037,987 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1240,005,447 - 40,038,025 (-)EnsemblGRCm38mm10GRCm38
MGSCv371240,759,878 - 40,764,574 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361240,543,714 - 40,548,410 (-)NCBIMGSCv36mm8
Celera1241,461,600 - 41,466,296 (-)NCBICelera
Cytogenetic Map12B1NCBI
cM Map1218.06NCBI
Arl4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8662,809,287 - 62,811,297 (-)NCBIGRCr8
mRatBN7.2657,079,496 - 57,084,156 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl657,078,812 - 57,085,066 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx657,345,445 - 57,347,455 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0657,660,381 - 57,662,391 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0657,151,623 - 57,153,633 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0659,945,926 - 59,950,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl659,948,577 - 59,950,586 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0669,534,037 - 69,538,697 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4659,212,599 - 59,214,609 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1659,215,725 - 59,217,735 (-)NCBI
Celera656,132,664 - 56,134,674 (-)NCBICelera
Cytogenetic Map6q21NCBI
Arl4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541016,400,342 - 16,403,200 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541016,400,342 - 16,403,200 (+)NCBIChiLan1.0ChiLan1.0
LOC100986273
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2617,553,211 - 17,558,311 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1765,877,927 - 65,881,296 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0713,379,627 - 13,383,603 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1712,723,991 - 12,727,761 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl712,725,299 - 12,725,901 (+)Ensemblpanpan1.1panPan2
ARL4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11427,522,766 - 27,526,404 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1427,034,654 - 27,036,978 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01427,349,211 - 27,351,535 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1427,349,181 - 27,351,535 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11427,519,115 - 27,521,438 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01427,249,798 - 27,252,122 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01427,566,321 - 27,568,645 (+)NCBIUU_Cfam_GSD_1.0
Arl4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511872,030,368 - 72,032,687 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936795355,256 - 357,515 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936795355,256 - 357,560 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARL4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12145,407,194 - 45,409,476 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604259,064,746 - 59,068,941 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arl4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473917,254,603 - 17,256,200 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473917,254,603 - 17,256,833 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ARL4A
66 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 7 1 1 1 1 3 2
Low 3 3 2 4 2 22 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000056123   ⟹   ENSSSCP00000037387
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl982,225,272 - 82,230,713 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000072139   ⟹   ENSSSCP00000066768
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl982,226,050 - 82,231,900 (+)Ensembl
RefSeq Acc Id: NM_001031791   ⟹   NP_001026961
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1982,226,697 - 82,227,299 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005667648   ⟹   XP_005667705
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1982,224,985 - 82,227,625 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005667649   ⟹   XP_005667706
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1982,225,999 - 82,228,951 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005667650   ⟹   XP_005667707
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1982,224,986 - 82,227,625 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005667651   ⟹   XP_005667708
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1982,225,999 - 82,228,951 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005667705   ⟸   XM_005667648
- Peptide Label: isoform X1
- UniProtKB: Q4ZJK1 (UniProtKB/TrEMBL),   A0A4X1TLJ2 (UniProtKB/TrEMBL),   A0A8D0VQT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005667707   ⟸   XM_005667650
- Peptide Label: isoform X1
- UniProtKB: Q4ZJK1 (UniProtKB/TrEMBL),   A0A4X1TLJ2 (UniProtKB/TrEMBL),   A0A8D0VQT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005667706   ⟸   XM_005667649
- Peptide Label: isoform X1
- UniProtKB: Q4ZJK1 (UniProtKB/TrEMBL),   A0A4X1TLJ2 (UniProtKB/TrEMBL),   A0A8D0VQT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005667708   ⟸   XM_005667651
- Peptide Label: isoform X1
- UniProtKB: Q4ZJK1 (UniProtKB/TrEMBL),   A0A4X1TLJ2 (UniProtKB/TrEMBL),   A0A8D0VQT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001026961   ⟸   NM_001031791
- UniProtKB: Q4ZJK1 (UniProtKB/TrEMBL),   A0A4X1TLJ2 (UniProtKB/TrEMBL),   A0A8D0VQT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000037387   ⟸   ENSSSCT00000056123
RefSeq Acc Id: ENSSSCP00000066768   ⟸   ENSSSCT00000072139


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000032709 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005005165 UniProtKB/TrEMBL
  ENSSSCG00015020585 UniProtKB/TrEMBL
  ENSSSCG00025029358 UniProtKB/TrEMBL
  ENSSSCG00030015950 UniProtKB/TrEMBL
  ENSSSCG00035035608 UniProtKB/TrEMBL
  ENSSSCG00040023360 UniProtKB/TrEMBL
  ENSSSCG00045004198 UniProtKB/TrEMBL
  ENSSSCG00050021884 UniProtKB/TrEMBL
  ENSSSCG00055023181 UniProtKB/TrEMBL
  ENSSSCG00060034159 UniProtKB/TrEMBL
  ENSSSCG00065023859 UniProtKB/TrEMBL
  ENSSSCG00070009911 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000056123 ENTREZGENE
  ENSSSCT00000056123.2 UniProtKB/TrEMBL
  ENSSSCT00000072139 ENTREZGENE
  ENSSSCT00000072139.2 UniProtKB/TrEMBL
  ENSSSCT00005007702.1 UniProtKB/TrEMBL
  ENSSSCT00005007726.1 UniProtKB/TrEMBL
  ENSSSCT00015027205.1 UniProtKB/TrEMBL
  ENSSSCT00015027266.1 UniProtKB/TrEMBL
  ENSSSCT00015027438.1 UniProtKB/TrEMBL
  ENSSSCT00025039972.1 UniProtKB/TrEMBL
  ENSSSCT00025040044.1 UniProtKB/TrEMBL
  ENSSSCT00030022100.1 UniProtKB/TrEMBL
  ENSSSCT00030022109.1 UniProtKB/TrEMBL
  ENSSSCT00030022118.1 UniProtKB/TrEMBL
  ENSSSCT00030022130.1 UniProtKB/TrEMBL
  ENSSSCT00035047201.1 UniProtKB/TrEMBL
  ENSSSCT00035047204.1 UniProtKB/TrEMBL
  ENSSSCT00035047208.1 UniProtKB/TrEMBL
  ENSSSCT00040031323.1 UniProtKB/TrEMBL
  ENSSSCT00040031360.1 UniProtKB/TrEMBL
  ENSSSCT00045006999.1 UniProtKB/TrEMBL
  ENSSSCT00045007000.1 UniProtKB/TrEMBL
  ENSSSCT00050029502.1 UniProtKB/TrEMBL
  ENSSSCT00050029523.1 UniProtKB/TrEMBL
  ENSSSCT00050029548.1 UniProtKB/TrEMBL
  ENSSSCT00050029567.1 UniProtKB/TrEMBL
  ENSSSCT00055045587.1 UniProtKB/TrEMBL
  ENSSSCT00055045615.1 UniProtKB/TrEMBL
  ENSSSCT00060046316.1 UniProtKB/TrEMBL
  ENSSSCT00060046330.1 UniProtKB/TrEMBL
  ENSSSCT00065031763.1 UniProtKB/TrEMBL
  ENSSSCT00065031765.1 UniProtKB/TrEMBL
  ENSSSCT00065031767.1 UniProtKB/TrEMBL
  ENSSSCT00070019268.1 UniProtKB/TrEMBL
  ENSSSCT00070019293.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase_ARF/SAR UniProtKB/TrEMBL
KEGG Report ssc:595121 UniProtKB/TrEMBL
NCBI Gene ARL4A ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 4A UniProtKB/TrEMBL
  PTHR11711 UniProtKB/TrEMBL
Pfam Arf UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
SMART ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  SAR UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A4X1TLJ2 ENTREZGENE
  A0A8D0VQT6 ENTREZGENE, UniProtKB/TrEMBL
  Q4ZJK1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1TLJ2 UniProtKB/TrEMBL
VGNC ID VGNC:85522 ENTREZGENE