CKM (creatine kinase, M-type) - Rat Genome Database

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Gene: CKM (creatine kinase, M-type) Sus scrofa
Analyze
Symbol: CKM
Name: creatine kinase, M-type
RGD ID: 14152056
Description: ENCODES a protein that exhibits creatine kinase activity (ortholog); INVOLVED IN phosphocreatine biosynthetic process (ortholog); response to heat (ortholog); PARTICIPATES IN creatine metabolic pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); Colonic Neoplasms (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CPK-M; creatine kinase M chain; creatine kinase M-type; creatine phosphokinase M-type; M-CK; muscle creatine kinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,700,507 - 51,714,814 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,704,021 - 51,716,935 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig Cytomap6q22-6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
extracellular space  (IBA,IEA,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:27606901   PMID:30032202  


Genomics

Comparative Map Data
CKM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,700,507 - 51,714,814 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,704,021 - 51,716,935 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig Cytomap6q22-6q23NCBI
CKM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,306,413 - 45,322,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,306,413 - 45,322,875 (-)EnsemblGRCh38hg38GRCh38
GRCh371945,809,671 - 45,826,133 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,501,511 - 50,517,974 (-)NCBINCBI36Build 36hg18NCBI36
Build 341950,501,511 - 50,517,974NCBI
Celera1942,615,239 - 42,631,814 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,241,505 - 42,258,552 (-)NCBIHuRef
CHM1_11945,812,972 - 45,829,550 (-)NCBICHM1_1
T2T-CHM13v2.01948,133,088 - 48,149,564 (-)NCBIT2T-CHM13v2.0
Ckm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,145,019 - 19,155,508 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,138,701 - 19,156,766 (+)EnsemblGRCm39 Ensembl
GRCm38719,411,094 - 19,421,583 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,404,776 - 19,422,841 (+)EnsemblGRCm38mm10GRCm38
MGSCv37719,996,443 - 20,006,932 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,569,616 - 18,580,105 (+)NCBIMGSCv36mm8
Celera716,817,487 - 16,827,978 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.67NCBI
Ckm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,189,382 - 88,199,717 (+)NCBIGRCr8
mRatBN7.2179,061,390 - 79,071,721 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,061,456 - 79,071,720 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,450,252 - 84,460,444 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0193,008,139 - 93,018,387 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,205,352 - 86,215,542 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,321,507 - 80,331,841 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,321,585 - 80,331,841 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,587,884 - 81,598,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,762,202 - 78,772,681 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,840,312 - 78,850,792 (+)NCBI
Celera173,523,369 - 73,533,981 (+)NCBICelera
RH 3.4 Map1787.5RGD
Cytogenetic Map1q21NCBI
Ckm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555552,318,072 - 2,336,811 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555552,318,072 - 2,330,733 (-)NCBIChiLan1.0ChiLan1.0
CKM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,466,605 - 51,482,812 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,336,131 - 53,354,359 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,255,158 - 42,271,467 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11950,854,556 - 50,870,366 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1950,854,556 - 50,870,366 (-)Ensemblpanpan1.1panPan2
CKM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,210,158 - 110,218,937 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,210,152 - 110,343,383 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,692,858 - 109,701,637 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,741,228 - 110,750,012 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,739,646 - 110,876,550 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,416,843 - 110,425,622 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,050,951 - 110,059,969 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,920,541 - 110,929,325 (+)NCBIUU_Cfam_GSD_1.0
Ckm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,444,955 - 17,453,704 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,790,958 - 1,801,139 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,792,298 - 1,801,063 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CKM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,764,229 - 38,778,718 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl638,763,402 - 38,776,301 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,361,677 - 18,377,016 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ckm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249072,215,157 - 2,226,889 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249072,215,260 - 2,226,891 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CKM
109 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High 2
Medium 2 2
Low 6 2 2 4 2 1
Below cutoff 2 2 1 3 17 2 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001129949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021093541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021093542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021093543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF165173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK240051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK390624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK390627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK390773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK394595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK394621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK394641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK394699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK398294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM040048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY754869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ153192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01087186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000041497   ⟹   ENSSSCP00000045315
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl651,699,165 - 51,714,811 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000075869   ⟹   ENSSSCP00000061534
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl651,704,083 - 51,712,422 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000087584   ⟹   ENSSSCP00000070358
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl651,700,507 - 51,712,422 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000093010   ⟹   ENSSSCP00000078844
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl651,700,507 - 51,714,814 (-)Ensembl
RefSeq Acc Id: NM_001129949   ⟹   NP_001123421
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1651,704,025 - 51,714,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093541   ⟹   XP_020949200
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1651,704,021 - 51,715,181 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093542   ⟹   XP_020949201
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1651,704,021 - 51,716,935 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093543   ⟹   XP_020949202
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1651,704,021 - 51,712,446 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020949201   ⟸   XM_021093542
- Peptide Label: isoform X1
- UniProtKB: A0A5G2QZN6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020949200   ⟸   XM_021093541
- Peptide Label: isoform X1
- UniProtKB: A0A5G2QZN6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020949202   ⟸   XM_021093543
- Peptide Label: isoform X1
- UniProtKB: A0A5G2QZN6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001123421   ⟸   NM_001129949
- UniProtKB: Q45EW9 (UniProtKB/Swiss-Prot),   Q5XLD3 (UniProtKB/Swiss-Prot),   A0A5G2QZN6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000045315   ⟸   ENSSSCT00000041497
RefSeq Acc Id: ENSSSCP00000061534   ⟸   ENSSSCT00000075869
RefSeq Acc Id: ENSSSCP00000070358   ⟸   ENSSSCT00000087584
RefSeq Acc Id: ENSSSCP00000078844   ⟸   ENSSSCT00000093010
Protein Domains
Phosphagen kinase C-terminal   Phosphagen kinase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000036132 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005021466 UniProtKB/Swiss-Prot
  ENSSSCG00015006617 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00025045630 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00030060031 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00035068926 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00040061159 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00045036676 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00055011557 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00060027142 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00065001659 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00070028309 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000075869 ENTREZGENE
  ENSSSCT00000075869.2 UniProtKB/TrEMBL
  ENSSSCT00000087584 ENTREZGENE
  ENSSSCT00000087584.1 UniProtKB/TrEMBL
  ENSSSCT00000093010.1 UniProtKB/TrEMBL
  ENSSSCT00005034041.1 UniProtKB/Swiss-Prot
  ENSSSCT00015008842.1 UniProtKB/Swiss-Prot
  ENSSSCT00015008931.1 UniProtKB/TrEMBL
  ENSSSCT00025061951.1 UniProtKB/Swiss-Prot
  ENSSSCT00025062061.1 UniProtKB/TrEMBL
  ENSSSCT00030083879.1 UniProtKB/Swiss-Prot
  ENSSSCT00030083909.1 UniProtKB/TrEMBL
  ENSSSCT00030083964.1 UniProtKB/TrEMBL
  ENSSSCT00030084010.1 UniProtKB/Swiss-Prot
  ENSSSCT00035093091.1 UniProtKB/TrEMBL
  ENSSSCT00035093171.1 UniProtKB/Swiss-Prot
  ENSSSCT00040083237.1 UniProtKB/TrEMBL
  ENSSSCT00040083461.1 UniProtKB/Swiss-Prot
  ENSSSCT00040083572.1 UniProtKB/TrEMBL
  ENSSSCT00045063185.1 UniProtKB/TrEMBL
  ENSSSCT00045063279.1 UniProtKB/Swiss-Prot
  ENSSSCT00045063316.1 UniProtKB/TrEMBL
  ENSSSCT00055022622.1 UniProtKB/TrEMBL
  ENSSSCT00055022694.1 UniProtKB/Swiss-Prot
  ENSSSCT00060036759.1 UniProtKB/TrEMBL
  ENSSSCT00060036770.1 UniProtKB/Swiss-Prot
  ENSSSCT00060036784.1 UniProtKB/TrEMBL
  ENSSSCT00065002071.1 UniProtKB/Swiss-Prot
  ENSSSCT00065002080.1 UniProtKB/TrEMBL
  ENSSSCT00070056777.1 UniProtKB/TrEMBL
  ENSSSCT00070056778.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.135.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutamine synthetase/guanido kinase, catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ATP-guanido_PTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-guanido_PTrfase_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gln_synth/guanido_kin_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397264 UniProtKB/Swiss-Prot
NCBI Gene CKM ENTREZGENE
PANTHER CREATINE KINASE M-TYPE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11547 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ATP-gua_Ptrans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-gua_PtransN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PHOSPHAGEN_KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHAGEN_KINASE_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHAGEN_KINASE_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48034 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55931 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287AMP3_PIG UniProtKB/TrEMBL
  A0A5G2QZN6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0S415_PIG UniProtKB/TrEMBL
  A0A8D1L9L8_PIG UniProtKB/TrEMBL
  A0A8W4FIY7_PIG UniProtKB/TrEMBL
  KCRM_PIG UniProtKB/Swiss-Prot
  Q45EW9 ENTREZGENE
  Q4LAX1_PIG UniProtKB/TrEMBL
  Q5XLD3 ENTREZGENE
UniProt Secondary A0A5G2QBV6 UniProtKB/TrEMBL
  Q45EW9 UniProtKB/Swiss-Prot
VGNC ID VGNC:96952 ENTREZGENE