CCDC68 (coiled-coil domain containing 68)

Gene: CCDC68 (coiled-coil domain containing 68) Sus scrofa

Analyze

Symbol:

CCDC68

Name:

coiled-coil domain containing 68

RGD ID:

14150523

Description:

INVOLVED IN intracellular signal transduction (inferred); microtubule anchoring at centrosome (inferred); protein localization (inferred); ASSOCIATED WITH genetic disease (ortholog); Habitual Abortions (ortholog); intellectual disability (ortholog); FOUND IN centriolar subdistal appendage (inferred); centriole (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

coiled-coil domain-containing protein 68

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	104,424,001 - 104,474,489 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	104,424,413 - 104,474,581 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	114,765,620 - 114,802,011 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Habitual Abortions (ISO)

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular signal transduction (IBA,IEA)

microtubule anchoring at centrosome (IEA)

protein localization (IEA)

Cellular Component

centriolar subdistal appendage (IEA)

centriole (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

CCDC68
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	104,424,001 - 104,474,489 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	104,424,413 - 104,474,581 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	114,765,620 - 114,802,011 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCDC68
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	54,901,509 - 54,959,461 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	54,901,509 - 54,959,461 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	52,568,740 - 52,626,692 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	50,719,791 - 50,777,635 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	18	49,286,315 - 49,344,306 (-)	NCBI		Celera
Cytogenetic Map	18	q21.2	NCBI
HuRef	18	49,277,953 - 49,335,856 (-)	NCBI		HuRef
CHM1_1	18	52,563,986 - 52,622,029 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	55,104,591 - 55,162,630 (-)	NCBI		T2T-CHM13v2.0

Ccdc68
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	70,057,929 - 70,102,559 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	70,058,497 - 70,102,555 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	69,924,858 - 69,969,488 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	69,925,426 - 69,969,484 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	70,085,213 - 70,129,138 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	70,050,928 - 70,094,853 (+)	NCBI		MGSCv36	mm8
Celera	18	71,216,513 - 71,260,561 (+)	NCBI		Celera
Cytogenetic Map	18	E2	NCBI
cM Map	18	43.78	NCBI

Ccdc68
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	65,817,232 - 65,859,529 (+)	NCBI		GRCr8
mRatBN7.2	18	63,541,828 - 63,584,122 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	63,541,896 - 63,584,119 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	65,632,130 - 65,674,399 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	66,310,463 - 66,352,696 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	64,192,155 - 64,234,401 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	68,408,812 - 68,472,323 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	68,408,890 - 68,472,320 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	67,564,633 - 67,626,014 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	66,623,573 - 66,665,814 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	18	61,636,522 - 61,676,187 (+)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

Ccdc68
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	39,423,316 - 39,493,809 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	39,426,158 - 39,493,655 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCDC68
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	72,426,763 - 72,484,388 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	58,108,866 - 58,177,003 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	48,280,443 - 48,337,823 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	51,616,129 - 51,660,189 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	51,616,129 - 51,658,312 (-)	Ensembl	panpan1.1		panPan2

CCDC68
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	20,644,302 - 20,688,615 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	20,656,190 - 20,687,998 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	21,623,176 - 21,674,467 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	20,524,860 - 20,576,165 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	20,539,287 - 20,576,143 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	20,578,407 - 20,629,637 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	20,473,432 - 20,524,590 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	20,745,160 - 20,796,344 (+)	NCBI		UU_Cfam_GSD_1.0

Ccdc68
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	33,751,766 - 33,795,620 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936497	9,005,157 - 9,034,486 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936497	8,990,841 - 9,035,498 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCDC68
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	24,746,806 - 24,803,950 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666060	735,254 - 791,257 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccdc68
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624792	378,711 - 446,932 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624792	375,934 - 541,040 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CCDC68
1132 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium								1
Low	10	2	3		2	3	1	2
Below cutoff		2		5		18	1		1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_001926362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU469481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01006610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000005008 ⟹ ENSSSCP00000004888

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	1	104,424,001 - 104,474,489 (-)	Ensembl

RefSeq Acc Id:

XM_001926362 ⟹ XP_001926397

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	1	104,424,413 - 104,474,581 (-)	NCBI

Sequence:

show sequence

GCGCTCCCTGAGGGGTGGAGCCAGCCAGCCCCACGGAGAAGACTCAGCCCAGGTCCAGAGCCGA
GGGGAGGAGCAGCGGCAGAATCCTGCTCTGGCTGAGCGCCCTCCAAGGTAGACGAGCCCCTGCG
ATCCGCGCACAGGTCACCCCCAGGGAATCTGGCTTTAATGTGATGGAAACACTCTTGATCTTGG
TGTCCAAAACATGAAGGTTTGACTCTGAGCTCTGTTAGTTTTACTGTGATTTGGGCTGGACTTC
ACAATGACAACAGTTCCCCTGAGGGGCAAGATAGAAGATCATTCTGCCTCATTTGAGTCCACCT
CAGCTCATATTATTGAAGAAACTGAATATGTGAAAAAGATTCGAACTACTCTGGAAAAGATCCG
AAACCAAATATTTAAAGATGAAGTGAGACATAACAGTACAAATCACAGACTAGATGCAAAGCAC
TATGGAAACATTCAAAATGCCTCTGACTCTGAAATGGATCCTTCTTGCAGTTTGGATCTGCTCA
TGGAAAGGATAAAAGGAAAAGACCGGCAGCTCTTAGAGATGAACAAAGAGAATGAAGTATTGAA
AATCAAGCTGGAAGCCTCCAGAGAAGCCGGAGCGGCGGCTCTGAGAAATGTGGCCCAGAGATTA
TTTGAAAACTATCAAACACAGTCTGAGGAAGCTAGAAAGAAGCATGAGGACAATAGACACTTAC
TCCAGGTTAACAAACTTGAAAAAGAACAGAAATTGAACCACCATGTTGAAAATCTGAATCAAAT
TGCTGAAAAGCTTGAAGAAAAACATAATCAAATCACGGAGTTGGAAAATCTTGTACAGAGAATG
GAAAAGGAAAAGAGAACACTGCTAGACAAAAAACTGTCTTTGGAAAACAAGCTGCTGCATCTCA
AATCCACCACTACTTATCCTAAAAGTTGCCAGGATCTTCAAAAGGAGATTTCCCTCCTCCAGGA
GCAGATCGCTCATCTACAGTTTGTGATTCACTCCCAGCATCAGAACCTGCGAAGTGTCATCCAG
GAGATGGAAGACTTAAAAAATAATTTAAAAGAACAAGATAAAAGAATTGAAAATCTGAAAGAAA
AAGTGAACATACTTGAAGCCCAGAACAAAGAACTAAAAACCAAGGTGGCTCTTTGTTCTGAAAC
TCCCAGGACAAAGGTGTCTAAGGCTGTCTCTACAAGTGAATTGAAGACTGAAGGCACAACCCCA
TATCTGATGTTGGTAAGGCTGCGGAAATGAGCTGGCTGCCTGGAGATCTGAATGAGGAAGATCA
TCATATGGGTCTTATTTATTCCTTGAAACACAGTCTAAGTGTACATATTAAAATGGCTTGGTGC
CAGTATTTAATGGAATTTATTGTATTTAATACATATATCGACAGCTTTGCAGGAAGGTGACATT
TCAGAAAATTAAATACATATTCAATGAAAGGAACTCTTTCTTCAAAACTTACTAAATGGATGAA
GAAATCAGTTGCTTTCCTGTGATGGAAGATGAATTCTGCTTTAAACTTTTAAAAAAATCAAAAA
TCTGTTTGTTTTTTTTTGTTTGTTTGTTTGAAGATTTTTGCTGAAGGGACTGGTTAAGGTTGTC
AACTTTGACTTTTTGATAGTGGCTTTTATGTATAGTTACCCCTTGGTATCCATGAGGGATTGGT
TCCAGGAGCCACCTGGGGTACCAAAACCCATGTGGATGCTCAAATCCTATCTATAAAATGGCAA
ATTATAGTTGATTCTCTGTATGCATGGTACCACATCCACTGATTCAGCCAATCATGGATGCAGA
ACCTGCAGATACAGAGGGCCTGCTATATATAAATATAAGGAAGAGTGTACAGACAGACCTCCTT
TCATTGTGCCTCACAGATACTGATGTTTACAAATTGAAGGTTTGTGGGAACCCTGCATTGTCAG
ATGATGGTTAGCATTTTTTCAGCAATAAAGTGTTTTTAATGTAATTTAATTTAAGTATTAGACA
TAATAATATTGCATACTTAATAGGCTACAGGACAGTGTAAATATAACTTTTATATGCACTGGGA
AACTGGAAATTTCATGTGACTCACTTCACTGTAATAGTCTCTTTATTGCGGTGCTCTGGAAACA
AACCTCTGCATCTCTGAGGGATATCTGTGAATAAATAATATTTTAAATATTTGACTTTTGAGTA
ATACAAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_001926397	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000004888
	ENSSSCP00000004888.3
	ENSSSCP00015012826.1
	ENSSSCP00025044657.1
	ENSSSCP00030017280.1
	ENSSSCP00035046165.1
	ENSSSCP00040048807.1
	ENSSSCP00045027031.1
	ENSSSCP00050001490.1
	ENSSSCP00055048355.1
	ENSSSCP00060027273.1
	ENSSSCP00065012510.1
	ENSSSCP00070026820.1

RefSeq Acc Id:

XP_001926397 ⟸ XM_001926362

- UniProtKB:

F1S1Z2 (UniProtKB/TrEMBL), A0A8D1Y3L4 (UniProtKB/TrEMBL), A0A4X1UCT6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTTVPLRGKIEDHSASFESTSAHIIEETEYVKKIRTTLEKIRNQIFKDEVRHNSTNHRLDAKHY
GNIQNASDSEMDPSCSLDLLMERIKGKDRQLLEMNKENEVLKIKLEASREAGAAALRNVAQRLF
ENYQTQSEEARKKHEDNRHLLQVNKLEKEQKLNHHVENLNQIAEKLEEKHNQITELENLVQRME
KEKRTLLDKKLSLENKLLHLKSTTTYPKSCQDLQKEISLLQEQIAHLQFVIHSQHQNLRSVIQE
MEDLKNNLKEQDKRIENLKEKVNILEAQNKELKTKVALCSETPRTKVSKAVSTSELKTEGTTPY
LMLVRLRK

hide sequence

RefSeq Acc Id:

ENSSSCP00000004888 ⟸ ENSSSCT00000005008

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000004534	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015024376	UniProtKB/TrEMBL
	ENSSSCG00025073418	UniProtKB/TrEMBL
	ENSSSCG00030026961	UniProtKB/TrEMBL
	ENSSSCG00035078379	UniProtKB/TrEMBL
	ENSSSCG00040076339	UniProtKB/TrEMBL
	ENSSSCG00045022786	UniProtKB/TrEMBL
	ENSSSCG00050003042	UniProtKB/TrEMBL
	ENSSSCG00055030338	UniProtKB/TrEMBL
	ENSSSCG00060046828	UniProtKB/TrEMBL
	ENSSSCG00065023004	UniProtKB/TrEMBL
	ENSSSCG00070016330	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000005008	ENTREZGENE
	ENSSSCT00000005008.4	UniProtKB/TrEMBL
	ENSSSCT00015032310.1	UniProtKB/TrEMBL
	ENSSSCT00025101070.1	UniProtKB/TrEMBL
	ENSSSCT00030037690.1	UniProtKB/TrEMBL
	ENSSSCT00035107007.1	UniProtKB/TrEMBL
	ENSSSCT00040106282.1	UniProtKB/TrEMBL
	ENSSSCT00045038876.1	UniProtKB/TrEMBL
	ENSSSCT00050003986.1	UniProtKB/TrEMBL
	ENSSSCT00055060358.1	UniProtKB/TrEMBL
	ENSSSCT00060063583.1	UniProtKB/TrEMBL
	ENSSSCT00065030608.1	UniProtKB/TrEMBL
	ENSSSCT00070032148.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.1490	UniProtKB/TrEMBL
KEGG Report	ssc:100152360	UniProtKB/TrEMBL
NCBI Gene	CCDC68	ENTREZGENE
PANTHER	GDOWN1	UniProtKB/TrEMBL
	PTHR23171:SF3	UniProtKB/TrEMBL
UniProt	A0A4X1UCT6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1Y3L4	ENTREZGENE, UniProtKB/TrEMBL
	F1S1Z2	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:86308	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar