CA5A (carbonic anhydrase 5A) - Rat Genome Database

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Gene: CA5A (carbonic anhydrase 5A) Sus scrofa
Analyze
Symbol: CA5A
Name: carbonic anhydrase 5A
RGD ID: 14150455
Description: ENCODES a protein that exhibits carbonate dehydratase activity (ortholog); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); CARBONIC ANHYDRASE VA DEFICIENCY, HYPERAMMONEMIA DUE TO (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: carbonic anhydrase 5A, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,505,566 - 1,538,494 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.161,495,615 - 1,539,390 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
mitochondrion  (IBA,IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:14681463  


Genomics

Comparative Map Data
CA5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl61,505,566 - 1,538,494 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.161,495,615 - 1,539,390 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CA5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1687,881,546 - 87,936,580 (-)EnsemblGRCh38hg38GRCh38
GRCh381687,881,549 - 87,936,575 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371687,915,155 - 87,970,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361686,479,126 - 86,527,613 (-)NCBINCBI36hg18NCBI36
Build 341686,479,125 - 86,527,613NCBI
Celera1672,219,173 - 72,267,375 (-)NCBI
Cytogenetic Map16q24.2NCBI
HuRef1673,662,132 - 73,710,650 (-)NCBIHuRef
CHM1_11689,333,043 - 89,381,480 (-)NCBICHM1_1
Car5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398122,642,874 - 122,671,651 (-)NCBIGRCm39mm39
GRCm39 Ensembl8122,642,865 - 122,671,643 (-)Ensembl
GRCm388121,916,135 - 121,944,912 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8121,916,126 - 121,944,904 (-)EnsemblGRCm38mm10GRCm38
MGSCv378124,440,035 - 124,468,812 (-)NCBIGRCm37mm9NCBIm37
MGSCv368121,987,915 - 122,017,051 (-)NCBImm8
MGSCv368124,802,236 - 124,830,994 (-)NCBImm8
Celera8126,138,230 - 126,172,629 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.81NCBI
Ca5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21949,973,092 - 50,002,948 (-)NCBI
Rnor_6.0 Ensembl1954,731,859 - 54,761,670 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01954,731,829 - 54,761,697 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01965,451,126 - 65,480,815 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,158,607 - 52,188,664 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,163,493 - 52,193,545 (-)NCBI
Celera1949,218,046 - 49,247,995 (-)NCBICelera
Cytogenetic Map19q12NCBI
Ca5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,139,920 - 2,160,597 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,141,450 - 2,159,955 (-)NCBIChiLan1.0ChiLan1.0
CA5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11687,887,288 - 87,903,159 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01668,564,400 - 68,618,614 (-)NCBIMhudiblu_PPA_v0panPan3
CA5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1565,269,855 - 65,297,593 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl565,269,635 - 65,296,777 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha565,280,118 - 65,307,768 (+)NCBI
ROS_Cfam_1.0565,489,652 - 65,517,389 (+)NCBI
UMICH_Zoey_3.1565,515,185 - 65,542,854 (+)NCBI
UNSW_CanFamBas_1.0565,346,901 - 65,374,559 (+)NCBI
UU_Cfam_GSD_1.0565,753,935 - 65,781,642 (+)NCBI
Ca5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,719,672 - 25,742,042 (+)NCBI
SpeTri2.0NW_0049366411,478,285 - 1,495,490 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA5A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1573,284,536 - 73,333,629 (-)NCBI
Ca5a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247461,293,619 - 1,323,067 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system musculoskeletal system nervous system reproductive system respiratory system
High
Medium
Low 6 2 6 1
Below cutoff 4 1 2 13 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000057346   ⟹   ENSSSCP00000040568
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl61,506,042 - 1,529,328 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000068954   ⟹   ENSSSCP00000071225
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl61,505,676 - 1,529,327 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000077090   ⟹   ENSSSCP00000070763
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl61,506,093 - 1,526,476 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000081582   ⟹   ENSSSCP00000069816
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl61,505,566 - 1,525,306 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000082715   ⟹   ENSSSCP00000069084
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl61,506,052 - 1,538,494 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000087799   ⟹   ENSSSCP00000066722
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl61,507,655 - 1,529,327 (+)Ensembl
RefSeq Acc Id: XM_021093672   ⟹   XP_020949331
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,787 - 1,539,389 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093673   ⟹   XP_020949332
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,615 - 1,539,389 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093674   ⟹   XP_020949333
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,784 - 1,539,390 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093675   ⟹   XP_020949334
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,786 - 1,539,390 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093676   ⟹   XP_020949335
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,942 - 1,529,330 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093677   ⟹   XP_020949336
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,941 - 1,526,467 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093678   ⟹   XP_020949337
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,941 - 1,524,992 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093680   ⟹   XP_020949339
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,942 - 1,529,330 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093681   ⟹   XP_020949340
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,941 - 1,524,992 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021093682   ⟹   XP_020949341
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.161,495,942 - 1,529,330 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020949332   ⟸   XM_021093673
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949333   ⟸   XM_021093674
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020949334   ⟸   XM_021093675
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020949331   ⟸   XM_021093672
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949336   ⟸   XM_021093677
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_020949337   ⟸   XM_021093678
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_020949340   ⟸   XM_021093681
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_020949335   ⟸   XM_021093676
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_020949341   ⟸   XM_021093682
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_020949339   ⟸   XM_021093680
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: ENSSSCP00000071225   ⟸   ENSSSCT00000068954
RefSeq Acc Id: ENSSSCP00000069816   ⟸   ENSSSCT00000081582
RefSeq Acc Id: ENSSSCP00000070763   ⟸   ENSSSCT00000077090
RefSeq Acc Id: ENSSSCP00000066722   ⟸   ENSSSCT00000087799
RefSeq Acc Id: ENSSSCP00000040568   ⟸   ENSSSCT00000057346
RefSeq Acc Id: ENSSSCP00000069084   ⟸   ENSSSCT00000082715
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000035629 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000040568 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000066722 UniProtKB/TrEMBL
  ENSSSCP00000069084 UniProtKB/TrEMBL
  ENSSSCP00000069816 UniProtKB/TrEMBL
  ENSSSCP00000070763 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000071225 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000057346 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000068954 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000077090 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000081582 UniProtKB/TrEMBL
  ENSSSCT00000082715 UniProtKB/TrEMBL
  ENSSSCT00000087799 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
NCBI Gene CA5A ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A287A9K7_PIG UniProtKB/TrEMBL
  A0A5G2QRM5_PIG UniProtKB/TrEMBL
  A0A5G2QVV1_PIG UniProtKB/TrEMBL
  A0A5G2QY19_PIG UniProtKB/TrEMBL
  A0A5G2R0X3_PIG UniProtKB/TrEMBL
  A0A5G2RAR3_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86101 ENTREZGENE