AK6 (adenylate kinase 6) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: AK6 (adenylate kinase 6) Sus scrofa
Analyze
Symbol: AK6
Name: adenylate kinase 6
RGD ID: 14150029
Description: ENCODES a protein that exhibits adenylate kinase activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN nucleoside monophosphate phosphorylation (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adenylate kinase isoenzyme 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1647,480,557 - 47,500,018 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11647,480,556 - 47,499,656 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21651,338,643 - 51,356,750 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Cajal body  (IEA)
centrosome  (IEA)
cytoplasm  (IEA)
nuclear speck  (IEA)
nucleolus  (ISO)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AK6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1647,480,557 - 47,500,018 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11647,480,556 - 47,499,656 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21651,338,643 - 51,356,750 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AK6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38569,350,984 - 69,369,824 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl569,350,984 - 69,370,013 (-)EnsemblGRCh38hg38GRCh38
GRCh37568,646,811 - 68,665,651 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map5q13.2NCBI
HuRef565,603,597 - 65,621,883 (-)NCBIHuRef
CHM1_1568,647,401 - 68,665,684 (-)NCBICHM1_1
T2T-CHM13v2.0570,176,769 - 70,195,609 (-)NCBIT2T-CHM13v2.0
Ak6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913100,787,851 - 100,802,923 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13100,787,487 - 100,802,867 (+)EnsemblGRCm39 Ensembl
GRCm3813100,651,343 - 100,666,415 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13100,650,979 - 100,666,359 (+)EnsemblGRCm38mm10GRCm38
Celera13104,261,518 - 104,276,058 (+)NCBICelera
Cytogenetic Map13D1NCBI
Ak6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8233,528,388 - 33,540,445 (+)NCBIGRCr8
mRatBN7.2231,794,316 - 31,806,375 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2025,576,483 - 25,576,998 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl231,794,519 - 31,806,371 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx238,928,842 - 38,940,871 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0236,969,330 - 36,981,235 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0231,827,274 - 31,839,138 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0230,664,407 - 30,676,464 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl230,664,217 - 30,676,464 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2027,129,291 - 27,129,806 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0249,824,043 - 49,836,100 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera227,807,006 - 27,818,863 (+)NCBICelera
Cytogenetic Map2q12NCBI
Ak6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495557560,481 - 78,415 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495557561,082 - 78,415 (-)NCBIChiLan1.0ChiLan1.0
AK6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2444,549,846 - 44,567,894 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1542,703,471 - 42,721,447 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0544,630,692 - 44,649,166 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1546,201,985 - 46,220,364 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl546,201,985 - 46,220,364 (+)Ensemblpanpan1.1panPan2
AK6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1254,390,411 - 54,406,872 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl254,390,411 - 54,406,872 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha251,356,906 - 51,373,134 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0254,901,418 - 54,917,916 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl254,901,418 - 54,917,942 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1251,960,190 - 51,976,409 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0252,735,500 - 52,749,699 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0253,623,775 - 53,640,092 (-)NCBIUU_Cfam_GSD_1.0
Ak6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213191,315,967 - 191,329,147 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936480252,435 - 265,605 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936480252,435 - 265,615 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AK6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1465,435,848 - 65,456,343 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl465,434,782 - 65,456,000 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604914,171,677 - 14,192,710 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ak6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624905228,706 - 244,656 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla_female_1.0 EnsemblNW_0046248052,392,044 - 2,392,637 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624905228,751 - 244,656 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AK6
617 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000046334   ⟹   ENSSSCP00000038414
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1647,480,557 - 47,500,018 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000070015   ⟹   ENSSSCP00000065011
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1647,481,472 - 47,499,493 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000070506   ⟹   ENSSSCP00000071738
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1647,481,048 - 47,499,692 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000087527   ⟹   ENSSSCP00000070180
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1647,480,557 - 47,499,478 (-)Ensembl
RefSeq Acc Id: XM_003134021   ⟹   XP_003134069
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11647,480,556 - 47,499,656 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013984839   ⟹   XP_013840293
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11647,481,553 - 47,499,653 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001301862
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11647,481,553 - 47,499,219 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003134069   ⟸   XM_003134021
- Peptide Label: isoform X2
- UniProtKB: A0A4X1UJ16 (UniProtKB/TrEMBL),   A0A4X1UKD8 (UniProtKB/TrEMBL),   A0A8D0JCW4 (UniProtKB/TrEMBL),   A0A8D1ISB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013840293   ⟸   XM_013984839
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000065011   ⟸   ENSSSCT00000070015
RefSeq Acc Id: ENSSSCP00000071738   ⟸   ENSSSCT00000070506
RefSeq Acc Id: ENSSSCP00000038414   ⟸   ENSSSCT00000046334
RefSeq Acc Id: ENSSSCP00000070180   ⟸   ENSSSCT00000087527


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037053 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005025269 UniProtKB/TrEMBL
  ENSSSCG00015044634 UniProtKB/TrEMBL
  ENSSSCG00025046913 UniProtKB/TrEMBL
  ENSSSCG00030045099 UniProtKB/TrEMBL
  ENSSSCG00035038374 UniProtKB/TrEMBL
  ENSSSCG00040045978 UniProtKB/TrEMBL
  ENSSSCG00045031822 UniProtKB/TrEMBL
  ENSSSCG00050056381 UniProtKB/TrEMBL
  ENSSSCG00055021115 UniProtKB/TrEMBL
  ENSSSCG00065075470 UniProtKB/TrEMBL
  ENSSSCG00070017355 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000046334 ENTREZGENE
  ENSSSCT00000046334.3 UniProtKB/TrEMBL
  ENSSSCT00000070506.2 UniProtKB/TrEMBL
  ENSSSCT00000087527.1 UniProtKB/TrEMBL
  ENSSSCT00005040280.1 UniProtKB/TrEMBL
  ENSSSCT00005040339.1 UniProtKB/TrEMBL
  ENSSSCT00005040387.1 UniProtKB/TrEMBL
  ENSSSCT00005040434.1 UniProtKB/TrEMBL
  ENSSSCT00015059659.1 UniProtKB/TrEMBL
  ENSSSCT00015059690.1 UniProtKB/TrEMBL
  ENSSSCT00015059742.1 UniProtKB/TrEMBL
  ENSSSCT00015059794.1 UniProtKB/TrEMBL
  ENSSSCT00025063796.1 UniProtKB/TrEMBL
  ENSSSCT00025063875.1 UniProtKB/TrEMBL
  ENSSSCT00025063967.1 UniProtKB/TrEMBL
  ENSSSCT00025064050.1 UniProtKB/TrEMBL
  ENSSSCT00030062935.1 UniProtKB/TrEMBL
  ENSSSCT00030062948.1 UniProtKB/TrEMBL
  ENSSSCT00030062965.1 UniProtKB/TrEMBL
  ENSSSCT00030062982.1 UniProtKB/TrEMBL
  ENSSSCT00035050925.1 UniProtKB/TrEMBL
  ENSSSCT00035050929.1 UniProtKB/TrEMBL
  ENSSSCT00035050935.1 UniProtKB/TrEMBL
  ENSSSCT00035050936.1 UniProtKB/TrEMBL
  ENSSSCT00040061842.1 UniProtKB/TrEMBL
  ENSSSCT00040061874.1 UniProtKB/TrEMBL
  ENSSSCT00040061934.1 UniProtKB/TrEMBL
  ENSSSCT00040061986.1 UniProtKB/TrEMBL
  ENSSSCT00045054355.1 UniProtKB/TrEMBL
  ENSSSCT00045054443.1 UniProtKB/TrEMBL
  ENSSSCT00045054504.1 UniProtKB/TrEMBL
  ENSSSCT00045054566.1 UniProtKB/TrEMBL
  ENSSSCT00050076888.1 UniProtKB/TrEMBL
  ENSSSCT00050076892.1 UniProtKB/TrEMBL
  ENSSSCT00055041527.1 UniProtKB/TrEMBL
  ENSSSCT00055041588.1 UniProtKB/TrEMBL
  ENSSSCT00055041674.1 UniProtKB/TrEMBL
  ENSSSCT00055041747.1 UniProtKB/TrEMBL
  ENSSSCT00065104150.1 UniProtKB/TrEMBL
  ENSSSCT00065104155.1 UniProtKB/TrEMBL
  ENSSSCT00065104161.1 UniProtKB/TrEMBL
  ENSSSCT00070034224.1 UniProtKB/TrEMBL
  ENSSSCT00070034227.1 UniProtKB/TrEMBL
  ENSSSCT00070034229.1 UniProtKB/TrEMBL
  ENSSSCT00070034235.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Adenyl_kinase_AK6 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report ssc:106504175 UniProtKB/TrEMBL
NCBI Gene AK6 ENTREZGENE
PANTHER ADENYLATE KINASE ISOENZYME 6 UniProtKB/TrEMBL
  PTHR12595 UniProtKB/TrEMBL
Pfam AAA_18 UniProtKB/TrEMBL
PRINTS SHIKIMTKNASE UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287A3E1_PIG UniProtKB/TrEMBL
  A0A4X1UJ16 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UJS7_PIG UniProtKB/TrEMBL
  A0A4X1UKD8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UKE4_PIG UniProtKB/TrEMBL
  A0A8D0JCW4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0S9A4_PIG UniProtKB/TrEMBL
  A0A8D0UT39_PIG UniProtKB/TrEMBL
  A0A8D1ISB7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1IY52_PIG UniProtKB/TrEMBL
  A0A8D1N1C1_PIG UniProtKB/TrEMBL
  A0A8D2A3G8_PIG UniProtKB/TrEMBL
  A0A8D2A627_PIG UniProtKB/TrEMBL
UniProt Secondary A0A5G2QJN8 UniProtKB/TrEMBL
  A0A5G2R1E8 UniProtKB/TrEMBL
  A0A5G2R3F9 UniProtKB/TrEMBL
VGNC ID VGNC:85211 ENTREZGENE