ADGRF4 (adhesion G protein-coupled receptor F4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: ADGRF4 (adhesion G protein-coupled receptor F4) Sus scrofa
Analyze
Symbol: ADGRF4
Name: adhesion G protein-coupled receptor F4
RGD ID: 14148268
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (inferred); cell surface receptor signaling pathway (inferred); G protein-coupled receptor signaling pathway (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADGRF2; adhesion G protein-coupled receptor F2; adhesion G-protein coupled receptor F2; G protein-coupled receptor 111; GPR111
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl742,373,211 - 42,430,700 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1742,357,184 - 42,401,773 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2392,015,231 - 92,060,068 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ADGRF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl742,373,211 - 42,430,700 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1742,357,184 - 42,401,773 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2392,015,231 - 92,060,068 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRF2P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38647,656,472 - 47,697,794 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl647,673,420 - 47,693,719 (+)EnsemblGRCh38hg38GRCh38
GRCh37647,624,208 - 47,665,530 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36647,732,285 - 47,766,296 (+)NCBINCBI36Build 36hg18NCBI36
Build 34647,732,181 - 47,758,379NCBI
Celera649,180,394 - 49,221,792 (+)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef647,352,079 - 47,393,449 (+)NCBIHuRef
CHM1_1647,627,133 - 47,668,488 (+)NCBICHM1_1
T2T-CHM13v2.0647,498,118 - 47,539,580 (+)NCBIT2T-CHM13v2.0
Adgrf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,004,919 - 43,054,646 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1743,007,021 - 43,053,070 (-)EnsemblGRCm39 Ensembl
GRCm381742,694,028 - 42,743,753 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1742,696,130 - 42,742,179 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1742,708,936 - 42,742,179 (-)EnsemblGRCm38mm10GRCm38
MGSCv371742,845,886 - 42,879,128 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361742,172,421 - 42,205,663 (-)NCBIMGSCv36mm8
Celera1746,129,553 - 46,162,658 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1719.66NCBI
Adgrf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8925,735,607 - 25,745,962 (+)NCBIGRCr8
mRatBN7.2918,238,389 - 18,248,745 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl918,219,714 - 18,269,038 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0920,898,943 - 20,948,284 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,917,673 - 20,950,386 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0919,771,781 - 19,810,350 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,960,770 - 13,973,241 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1913,936,316 - 13,968,349 (+)NCBI
Celera915,923,302 - 15,971,903 (+)NCBICelera
Cytogenetic Map9q13NCBI
Adgrf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543712,095,601 - 12,126,710 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543712,104,938 - 12,126,649 (+)NCBIChiLan1.0ChiLan1.0
LOC100991737
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2562,169,248 - 62,189,580 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1658,018,353 - 58,060,742 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0647,239,514 - 47,279,734 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1648,502,919 - 48,529,581 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl648,502,919 - 48,537,453 (+)Ensemblpanpan1.1panPan2
ADGRF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11215,716,866 - 15,739,690 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1215,701,981 - 15,735,213 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1215,733,024 - 15,770,650 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01216,204,945 - 16,242,393 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1216,204,948 - 16,240,571 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11215,714,103 - 15,751,846 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01215,806,684 - 15,844,322 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01215,954,135 - 15,991,995 (+)NCBIUU_Cfam_GSD_1.0
Adgrf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494651,086,555 - 51,123,314 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647612,836,901 - 12,857,743 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11724,595,746 - 24,632,284 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604447,671,850 - 47,721,653 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgrf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475413,383,349 - 13,414,132 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ADGRF4
1918 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system reproductive system respiratory system
High
Medium
Low 1 1 1
Below cutoff 1 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000023995   ⟹   ENSSSCP00000021241
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl742,404,491 - 42,426,340 (+)Ensembl
RefSeq Acc Id: XM_013996166   ⟹   XP_013851620
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1742,357,184 - 42,401,773 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013851620 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000021241.3
  ENSSSCP00045000015.1
  ENSSSCP00045000030.1
  ENSSSCP00055010514.1
  ENSSSCP00070034848.1
  ENSSSCP00070034855.1
  ENSSSCP00070034861.1
  ENSSSCP00070034869.1
Reference Protein Sequences
RefSeq Acc Id: XP_013851620   ⟸   XM_013996166
- UniProtKB: A0A4X1V2F0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000021241   ⟸   ENSSSCT00000023995
Protein Domains
G-protein coupled receptors family 2 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000022089 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00045000005 UniProtKB/TrEMBL
  ENSSSCG00045000077 UniProtKB/TrEMBL
  ENSSSCG00055006887 UniProtKB/TrEMBL
  ENSSSCG00070020875 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000023995.3 UniProtKB/TrEMBL
  ENSSSCT00045000055.1 UniProtKB/TrEMBL
  ENSSSCT00045000099.1 UniProtKB/TrEMBL
  ENSSSCT00055013373.1 UniProtKB/TrEMBL
  ENSSSCT00070041506.1 UniProtKB/TrEMBL
  ENSSSCT00070041513.1 UniProtKB/TrEMBL
  ENSSSCT00070041519.1 UniProtKB/TrEMBL
  ENSSSCT00070041529.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.220.50 UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_Ig-hepta-like_rcpt UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
NCBI Gene ADGRF2 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR F4 UniProtKB/TrEMBL
  ADHESION G-PROTEIN COUPLED RECEPTOR F2 UniProtKB/TrEMBL
  PTHR45813 UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
PRINTS GPCRSECRETIN UniProtKB/TrEMBL
  IGHEPTARCPTR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A4X1UZW5_PIG UniProtKB/TrEMBL
  A0A4X1V2E3_PIG UniProtKB/TrEMBL
  A0A4X1V2F0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1KNM1_PIG UniProtKB/TrEMBL
  A0A8D1PXC3_PIG UniProtKB/TrEMBL
  I3LB22_PIG UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-07-26 ADGRF4  adhesion G protein-coupled receptor F4  ADGRF2  adhesion G protein-coupled receptor F2  Symbol and/or name change 19259463 PROVISIONAL