HAL (histidine ammonia-lyase) - Rat Genome Database
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Gene: HAL (histidine ammonia-lyase) Sus scrofa
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Symbol: HAL
Name: histidine ammonia-lyase
RGD ID: 14148244
Description: ENCODES a protein that exhibits ammonia-lyase activity (inferred); histidine ammonia-lyase activity (inferred); INVOLVED IN histidine catabolic process to glutamate and formamide (inferred); histidine catabolic process to glutamate and formate (inferred); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); histidinemia (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl587,522,522 - 87,547,491 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1587,522,483 - 87,547,489 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2591,725,402 - 91,751,694 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
HAL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl587,522,522 - 87,547,491 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1587,522,483 - 87,547,489 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2591,725,402 - 91,751,694 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HAL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1295,972,662 - 95,996,365 (-)EnsemblGRCh38hg38GRCh38
GRCh381295,972,662 - 95,996,344 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371296,366,440 - 96,390,143 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361294,891,273 - 94,914,202 (-)NCBINCBI36hg18NCBI36
Build 341294,869,609 - 94,892,539NCBI
Celera1296,033,432 - 96,056,362 (-)NCBI
Cytogenetic Map12q23.1NCBI
HuRef1293,428,306 - 93,452,016 (-)NCBIHuRef
CHM1_11296,331,432 - 96,355,134 (-)NCBICHM1_1
Hal
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391093,324,630 - 93,352,623 (+)NCBIGRCm39mm39
GRCm381093,488,768 - 93,516,761 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1093,488,768 - 93,519,304 (+)EnsemblGRCm38mm10GRCm38
MGSCv371092,951,513 - 92,979,488 (+)NCBIGRCm37mm9NCBIm37
MGSCv361093,707,053 - 93,735,128 (+)NCBImm8
MGSCv361092,918,567 - 92,946,542 (+)NCBImm8
Celera1095,474,543 - 95,502,727 (+)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1048.49NCBI
Hal
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0734,326,087 - 34,356,413 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl734,326,087 - 34,356,413 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0734,391,142 - 34,421,405 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4730,520,913 - 30,551,145 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1730,541,183 - 30,571,416 (+)NCBI
Celera725,107,998 - 25,136,986 (+)NCBICelera
Cytogenetic Map7q13NCBI
RH 3.4 Map7191.8RGD
Hal
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540532,316,326 - 32,341,485 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540532,317,345 - 32,341,409 (-)NCBIChiLan1.0ChiLan1.0
HAL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11296,950,020 - 96,973,662 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1296,950,020 - 96,973,662 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01293,561,401 - 93,585,215 (-)NCBIMhudiblu_PPA_v0panPan3
HAL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1535,759,672 - 35,791,003 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11535,767,314 - 35,791,086 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Hal
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493650712,058,583 - 12,078,159 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HAL
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11191,343,715 - 91,367,384 (-)NCBI
Hal
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475011,318,572 - 11,344,326 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system respiratory system
High
Medium
Low 1 1 2
Below cutoff 7 1 2 2 4 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000000976   ⟹   ENSSSCP00000000955
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl587,522,524 - 87,547,491 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000052080   ⟹   ENSSSCP00000032962
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl587,522,524 - 87,547,491 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000073930   ⟹   ENSSSCP00000061267
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl587,522,522 - 87,546,238 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000088546   ⟹   ENSSSCP00000066171
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl587,522,524 - 87,547,491 (+)Ensembl
RefSeq Acc Id: XM_001925061   ⟹   XP_001925096
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1587,522,483 - 87,547,489 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001925096 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_001925096   ⟸   XM_001925061
- Sequence:
RefSeq Acc Id: ENSSSCP00000066171   ⟸   ENSSSCT00000088546
RefSeq Acc Id: ENSSSCP00000000955   ⟸   ENSSSCT00000000976
RefSeq Acc Id: ENSSSCP00000061267   ⟸   ENSSSCT00000073930
RefSeq Acc Id: ENSSSCP00000032962   ⟸   ENSSSCT00000052080
Protein Domains
Par3_HAL_N_term


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000892 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070001913 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000000955 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000032962 UniProtKB/TrEMBL
  ENSSSCP00000061267 UniProtKB/TrEMBL
  ENSSSCP00000066171 UniProtKB/TrEMBL
  ENSSSCP00070003015 UniProtKB/TrEMBL
  ENSSSCP00070003023 UniProtKB/TrEMBL
  ENSSSCP00070003029 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000976 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000052080 UniProtKB/TrEMBL
  ENSSSCT00000073930 UniProtKB/TrEMBL
  ENSSSCT00000088546 UniProtKB/TrEMBL
  ENSSSCT00070003632 UniProtKB/TrEMBL
  ENSSSCT00070003644 UniProtKB/TrEMBL
  ENSSSCT00070003651 UniProtKB/TrEMBL
Gene3D-CATH 1.10.275.10 UniProtKB/TrEMBL
InterPro Aromatic_Lyase UniProtKB/TrEMBL
  Fumarase/histidase_N UniProtKB/TrEMBL
  HutH UniProtKB/TrEMBL
  L-Aspartase-like UniProtKB/TrEMBL
  Par3/HAL_N UniProtKB/TrEMBL
  Phe/His_NH3-lyase_AS UniProtKB/TrEMBL
NCBI Gene HAL ENTREZGENE
PANTHER PTHR10362 UniProtKB/TrEMBL
Pfam Lyase_aromatic UniProtKB/TrEMBL
  Par3_HAL_N_term UniProtKB/TrEMBL
PROSITE PAL_HISTIDASE UniProtKB/TrEMBL
Superfamily-SCOP SSF48557 UniProtKB/TrEMBL
TIGRFAMs hutH UniProtKB/TrEMBL
UniGene Ssc.32439 ENTREZGENE
UniProt A0A286ZND0_PIG UniProtKB/TrEMBL
  A0A4X1SKS3_PIG UniProtKB/TrEMBL
  A0A4X1SLX6_PIG UniProtKB/TrEMBL
  A0A4X1SLZ9_PIG UniProtKB/TrEMBL
  A0A5G2QGX7_PIG UniProtKB/TrEMBL
  A0A5G2QQ33_PIG UniProtKB/TrEMBL
  F1SQR7_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88775 ENTREZGENE