NMNAT3 (nicotinamide nucleotide adenylyltransferase 3) - Rat Genome Database

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Gene: NMNAT3 (nicotinamide nucleotide adenylyltransferase 3) Sus scrofa
Analyze
Symbol: NMNAT3
Name: nicotinamide nucleotide adenylyltransferase 3
RGD ID: 14147884
Description: ENCODES a protein that exhibits adenylyltransferase activity (inferred); ATP binding (inferred); catalytic activity (inferred); INVOLVED IN NAD biosynthetic process (ortholog); response to tumor necrosis factor (ortholog); response to wounding (ortholog); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH glaucoma (ortholog); polycystic ovary syndrome (ortholog); FOUND IN axon (ortholog); neuronal cell body (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1380,429,639 - 80,556,790 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11380,431,405 - 80,556,808 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21388,294,211 - 88,321,441 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (ISO)
cytoplasm  (IEA)
mitochondrion  (IBA,IEA)
neuronal cell body  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NMNAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1380,429,639 - 80,556,790 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11380,431,405 - 80,556,808 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21388,294,211 - 88,321,441 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NMNAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383139,560,180 - 139,678,050 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3139,560,180 - 139,678,017 (-)EnsemblGRCh38hg38GRCh38
GRCh373139,279,022 - 139,396,892 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,761,723 - 140,879,530 (-)NCBINCBI36Build 36hg18NCBI36
Build 343140,761,731 - 140,879,538NCBI
Celera3137,701,933 - 137,819,739 (-)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3136,654,467 - 136,772,328 (-)NCBIHuRef
CHM1_13139,242,474 - 139,360,320 (-)NCBICHM1_1
T2T-CHM13v2.03142,307,606 - 142,425,486 (-)NCBIT2T-CHM13v2.0
Nmnat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,169,487 - 98,302,586 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,169,488 - 98,302,491 (+)EnsemblGRCm39 Ensembl
GRCm38998,287,433 - 98,420,533 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,287,435 - 98,420,438 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,197,002 - 98,311,847 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36998,105,935 - 98,220,780 (+)NCBIMGSCv36mm8
Celera997,850,409 - 97,963,936 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.35NCBI
Nmnat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88107,771,124 - 107,888,528 (+)NCBIGRCr8
mRatBN7.2898,892,168 - 99,003,912 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl898,873,398 - 99,020,645 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8104,561,145 - 104,672,788 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08102,760,392 - 102,872,044 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08100,602,906 - 100,714,552 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08106,317,038 - 106,429,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8106,317,124 - 106,429,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08105,760,369 - 105,871,374 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48103,472,426 - 103,584,246 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18103,491,880 - 103,603,693 (+)NCBI
Celera898,304,722 - 98,415,332 (+)NCBICelera
Cytogenetic Map8q31NCBI
Nmnat3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555085,913,898 - 6,022,128 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555085,909,808 - 6,024,301 (+)NCBIChiLan1.0ChiLan1.0
NMNAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,472,086 - 137,592,706 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13137,476,826 - 137,597,430 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,594,825 - 136,715,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13144,196,529 - 144,313,658 (-)NCBIpanpan1.1PanPan1.1panPan2
NMNAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12335,714,162 - 35,829,150 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2335,714,933 - 35,829,049 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2335,701,815 - 35,816,030 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02336,250,931 - 36,365,957 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2336,250,934 - 36,366,221 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12335,933,008 - 36,047,352 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02336,006,480 - 36,121,350 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02336,249,065 - 36,363,588 (-)NCBIUU_Cfam_GSD_1.0
Nmnat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560274,886,743 - 75,026,495 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365401,636,380 - 1,766,306 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365401,653,243 - 1,766,244 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NMNAT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11550,880,146 - 50,990,958 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1550,880,235 - 50,991,281 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604123,853,934 - 23,964,976 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nmnat3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473016,158,485 - 16,231,670 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473016,151,185 - 16,289,260 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NMNAT3
2726 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 20 3 2 5 14 12 20 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000024168   ⟹   ENSSSCP00000027527
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1380,431,404 - 80,556,681 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000028389   ⟹   ENSSSCP00000024710
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1380,431,413 - 80,556,790 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000067789   ⟹   ENSSSCP00000074102
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1380,429,639 - 80,556,622 (-)Ensembl
RefSeq Acc Id: XM_021069536   ⟹   XP_020925195
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11380,431,405 - 80,556,808 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069537   ⟹   XP_020925196
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11380,431,405 - 80,556,804 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069538   ⟹   XP_020925197
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11380,431,405 - 80,556,806 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020925195   ⟸   XM_021069536
- Peptide Label: isoform X1
- UniProtKB: A0A8D0URX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925197   ⟸   XM_021069538
- Peptide Label: isoform X3
- UniProtKB: A0A8D1DM59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020925196   ⟸   XM_021069537
- Peptide Label: isoform X2
- UniProtKB: F1SL51 (UniProtKB/TrEMBL),   A0A4X1TUY0 (UniProtKB/TrEMBL),   A0A8D0URX9 (UniProtKB/TrEMBL),   A0A8D0VPU5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000074102   ⟸   ENSSSCT00000067789
Ensembl Acc Id: ENSSSCP00000024710   ⟸   ENSSSCT00000028389
Ensembl Acc Id: ENSSSCP00000027527   ⟸   ENSSSCT00000024168
Protein Domains
Cytidyltransferase-like   Cytosolic fatty-acid binding proteins


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031142 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015060053 UniProtKB/TrEMBL
  ENSSSCG00025043015 UniProtKB/TrEMBL
  ENSSSCG00030015323 UniProtKB/TrEMBL
  ENSSSCG00035045593 UniProtKB/TrEMBL
  ENSSSCG00035046027 UniProtKB/TrEMBL
  ENSSSCG00040015653 UniProtKB/TrEMBL
  ENSSSCG00045009554 UniProtKB/TrEMBL
  ENSSSCG00050024243 UniProtKB/TrEMBL
  ENSSSCG00055017494 UniProtKB/TrEMBL
  ENSSSCG00055017764 UniProtKB/TrEMBL
  ENSSSCG00060027565 UniProtKB/TrEMBL
  ENSSSCG00065040553 UniProtKB/TrEMBL
  ENSSSCG00070012510 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000024168.4 UniProtKB/TrEMBL
  ENSSSCT00000028389 ENTREZGENE
  ENSSSCT00000028389.4 UniProtKB/TrEMBL
  ENSSSCT00000067789.1 UniProtKB/TrEMBL
  ENSSSCT00015080285.1 UniProtKB/TrEMBL
  ENSSSCT00015080729.1 UniProtKB/TrEMBL
  ENSSSCT00015080811.1 UniProtKB/TrEMBL
  ENSSSCT00015080974.1 UniProtKB/TrEMBL
  ENSSSCT00025058288.1 UniProtKB/TrEMBL
  ENSSSCT00025058543.1 UniProtKB/TrEMBL
  ENSSSCT00030021157.1 UniProtKB/TrEMBL
  ENSSSCT00030021167.1 UniProtKB/TrEMBL
  ENSSSCT00030021175.1 UniProtKB/TrEMBL
  ENSSSCT00030021182.1 UniProtKB/TrEMBL
  ENSSSCT00035060601.1 UniProtKB/TrEMBL
  ENSSSCT00035060613.1 UniProtKB/TrEMBL
  ENSSSCT00035060619.1 UniProtKB/TrEMBL
  ENSSSCT00035061192.1 UniProtKB/TrEMBL
  ENSSSCT00040021074.1 UniProtKB/TrEMBL
  ENSSSCT00040021097.1 UniProtKB/TrEMBL
  ENSSSCT00040021112.1 UniProtKB/TrEMBL
  ENSSSCT00040021120.1 UniProtKB/TrEMBL
  ENSSSCT00045016179.1 UniProtKB/TrEMBL
  ENSSSCT00045016211.1 UniProtKB/TrEMBL
  ENSSSCT00045016243.1 UniProtKB/TrEMBL
  ENSSSCT00045016274.1 UniProtKB/TrEMBL
  ENSSSCT00050032676.1 UniProtKB/TrEMBL
  ENSSSCT00050032679.1 UniProtKB/TrEMBL
  ENSSSCT00050032681.1 UniProtKB/TrEMBL
  ENSSSCT00050032683.1 UniProtKB/TrEMBL
  ENSSSCT00055034359.1 UniProtKB/TrEMBL
  ENSSSCT00055034475.1 UniProtKB/TrEMBL
  ENSSSCT00055034566.1 UniProtKB/TrEMBL
  ENSSSCT00055034628.1 UniProtKB/TrEMBL
  ENSSSCT00055034915.1 UniProtKB/TrEMBL
  ENSSSCT00060037315.1 UniProtKB/TrEMBL
  ENSSSCT00060037323.1 UniProtKB/TrEMBL
  ENSSSCT00060037328.1 UniProtKB/TrEMBL
  ENSSSCT00060037329.1 UniProtKB/TrEMBL
  ENSSSCT00065055442.1 UniProtKB/TrEMBL
  ENSSSCT00065055445.1 UniProtKB/TrEMBL
  ENSSSCT00065055448.1 UniProtKB/TrEMBL
  ENSSSCT00065055450.1 UniProtKB/TrEMBL
  ENSSSCT00070024456.1 UniProtKB/TrEMBL
  ENSSSCT00070024459.1 UniProtKB/TrEMBL
  ENSSSCT00070024471.1 UniProtKB/TrEMBL
  ENSSSCT00070024474.1 UniProtKB/TrEMBL
  ENSSSCT00070024493.1 UniProtKB/TrEMBL
  ENSSSCT00070024499.1 UniProtKB/TrEMBL
  ENSSSCT00070024500.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.128.20 UniProtKB/TrEMBL
  3.40.50.620 UniProtKB/TrEMBL
InterPro Calycin UniProtKB/TrEMBL
  Cyt_trans-like UniProtKB/TrEMBL
  Euk_NMN_adenylyltrnsfrase UniProtKB/TrEMBL
  Fatty_acid-bd UniProtKB/TrEMBL
  ILBP UniProtKB/TrEMBL
  Lipocln_cytosolic_FA-bd_dom UniProtKB/TrEMBL
  NadD/NMNAT UniProtKB/TrEMBL
  NMNAT_euk UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
NCBI Gene NMNAT3 ENTREZGENE
PANTHER NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE UniProtKB/TrEMBL
  NICOTINAMIDE/NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE 3 UniProtKB/TrEMBL
  PTHR11955 UniProtKB/TrEMBL
Pfam CTP_transf_like UniProtKB/TrEMBL
  Lipocalin UniProtKB/TrEMBL
PRINTS FATTYACIDBP UniProtKB/TrEMBL
PROSITE FABP UniProtKB/TrEMBL
Superfamily-SCOP Nucleotidylyl transferase UniProtKB/TrEMBL
  SSF50814 UniProtKB/TrEMBL
UniProt A0A4X1TSP8_PIG UniProtKB/TrEMBL
  A0A4X1TUY0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TXK4_PIG UniProtKB/TrEMBL
  A0A4X1TXS2_PIG UniProtKB/TrEMBL
  A0A4X1TXU7_PIG UniProtKB/TrEMBL
  A0A4X1TY22_PIG UniProtKB/TrEMBL
  A0A5G2RAR2_PIG UniProtKB/TrEMBL
  A0A8D0JFT6_PIG UniProtKB/TrEMBL
  A0A8D0U867_PIG UniProtKB/TrEMBL
  A0A8D0URX9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0VPU5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0ZVG4_PIG UniProtKB/TrEMBL
  A0A8D1A120_PIG UniProtKB/TrEMBL
  A0A8D1A583_PIG UniProtKB/TrEMBL
  A0A8D1DM59 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1YMS7_PIG UniProtKB/TrEMBL
  F1SL51 ENTREZGENE
  I3LTS9_PIG UniProtKB/TrEMBL
UniProt Secondary F1SL51 UniProtKB/TrEMBL
VGNC ID VGNC:108679 ENTREZGENE