GLRX2 (glutaredoxin 2) - Rat Genome Database
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Gene: GLRX2 (glutaredoxin 2) Sus scrofa
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Symbol: GLRX2
Name: glutaredoxin 2
RGD ID: 14142946
Description: ENCODES a protein that exhibits protein disulfide oxidoreductase activity (inferred); INVOLVED IN aging (ortholog); cellular response to superoxide (ortholog); response to hydrogen peroxide (ortholog); ASSOCIATED WITH Hyperparathyroidism 1 (ortholog); FOUND IN dendrite (ortholog); intracellular membrane-bounded organelle (ortholog); mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.110679,305 - 689,890 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
GLRX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.110679,305 - 689,890 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GLRX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1193,090,866 - 193,106,114 (-)EnsemblGRCh38hg38GRCh38
GRCh381193,096,465 - 193,106,114 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371193,065,595 - 193,075,659 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,332,223 - 191,341,867 (-)NCBINCBI36hg18NCBI36
Build 341189,797,256 - 189,806,213NCBI
Celera1166,175,205 - 166,184,851 (-)NCBI
Cytogenetic Map1q31.2NCBI
HuRef1164,301,400 - 164,311,051 (-)NCBIHuRef
CHM1_11194,487,507 - 194,497,577 (-)NCBICHM1_1
Glrx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391143,614,787 - 143,625,416 (+)NCBIGRCm39mm39
GRCm381143,739,224 - 143,749,678 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1143,716,338 - 143,749,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv371145,586,479 - 145,596,808 (+)NCBIGRCm37mm9NCBIm37
MGSCv361145,501,567 - 145,511,896 (+)NCBImm8
Celera1146,314,372 - 146,324,701 (+)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.53NCBI
Glrx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01360,529,057 - 60,552,115 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1360,529,932 - 60,537,916 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01365,517,621 - 65,540,676 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,567,017 - 57,589,873 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11357,581,096 - 57,603,951 (+)NCBI
Celera1355,569,577 - 55,592,422 (+)NCBICelera
Cytogenetic Map13q21NCBI
Glrx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540630,497,562 - 30,509,340 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540630,497,562 - 30,506,463 (-)NCBIChiLan1.0ChiLan1.0
GLRX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11172,848,858 - 172,859,970 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,849,013 - 172,859,062 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01168,555,858 - 168,565,949 (-)NCBIMhudiblu_PPA_v0panPan3
GLRX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl385,964,039 - 5,971,676 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1385,963,800 - 5,971,673 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Glrx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366381,325,076 - 1,333,994 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLRX2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,318,894 - 36,328,567 (+)NCBI
ChlSab1.1 Ensembl2536,319,637 - 36,328,417 (+)Ensembl
Glrx2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624814481,981 - 505,052 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 2 3 5 1 22 2 2 3
Low 2 1 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: NM_001243717   ⟹   NP_001230646
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.110679,328 - 687,349 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063986   ⟹   XP_020919645
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.110679,305 - 689,890 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001230646 (Get FASTA)   NCBI Sequence Viewer  
  XP_020919645 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020919645   ⟸   XM_021063986
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001230646   ⟸   NM_001243717
- Sequence:
Protein Domains
Glutaredoxin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031991 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070012241 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000040665 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000066072 UniProtKB/TrEMBL
  ENSSSCP00070019765 UniProtKB/TrEMBL
  ENSSSCP00070019770 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000053376 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000084369 UniProtKB/TrEMBL
  ENSSSCT00070023909 UniProtKB/TrEMBL
  ENSSSCT00070023915 UniProtKB/TrEMBL
Gene3D-CATH 3.40.30.10 UniProtKB/TrEMBL
InterPro Glutaredoxin UniProtKB/TrEMBL
  Glutaredoxin_euk/vir UniProtKB/TrEMBL
  Glutaredoxin_subgr UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
KEGG Report ssc:100511215 UniProtKB/TrEMBL
NCBI Gene GLRX2 ENTREZGENE
Pfam Glutaredoxin UniProtKB/TrEMBL
PRINTS GLUTAREDOXIN UniProtKB/TrEMBL
PROSITE GLUTAREDOXIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
TIGRFAMs GRX_euk UniProtKB/TrEMBL
UniProt A0A287A9I5_PIG UniProtKB/TrEMBL
  A0A4X1TWI0_PIG UniProtKB/TrEMBL
  A0A4X1TWI2_PIG UniProtKB/TrEMBL
  A0A5G2QMG6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:95730 ENTREZGENE