CHGA (chromogranin A) - Rat Genome Database

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Gene: CHGA (chromogranin A) Sus scrofa
Analyze
Symbol: CHGA
Name: chromogranin A
RGD ID: 14142759
Description: INVOLVED IN defense response to Gram-negative bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); mast cell activation (ortholog); PARTICIPATES IN G protein mediated signaling pathway; ASSOCIATED WITH achondrogenesis type IA (ortholog); end stage renal disease (ortholog); genetic disease (ortholog); FOUND IN chromaffin granule (ortholog); extracellular space (ortholog); neuronal dense core vesicle (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cgA; chromogranin A (parathyroid secretory protein 1); chromogranin-A; pancreastatin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7114,345,305 - 114,358,075 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17114,345,542 - 114,357,799 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27120,954,018 - 120,966,278 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:2105940   PMID:2834189   PMID:3537810   PMID:8344192   PMID:12826904   PMID:14681463   PMID:17145712   PMID:17407547   PMID:24507880   PMID:24752611   PMID:30032202  


Genomics

Comparative Map Data
CHGA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7114,345,305 - 114,358,075 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17114,345,542 - 114,357,799 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27120,954,018 - 120,966,278 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHGA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381492,922,664 - 92,935,285 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1492,923,150 - 92,935,285 (+)EnsemblGRCh38hg38GRCh38
GRCh371493,389,495 - 93,401,630 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361492,459,198 - 92,471,391 (+)NCBINCBI36Build 36hg18NCBI36
Build 341492,459,244 - 92,471,389NCBI
Celera1473,443,584 - 73,455,777 (+)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1473,571,127 - 73,583,341 (+)NCBIHuRef
CHM1_11493,327,694 - 93,339,887 (+)NCBICHM1_1
T2T-CHM13v2.01487,154,582 - 87,167,278 (+)NCBIT2T-CHM13v2.0
Chga
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912102,521,200 - 102,531,286 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12102,521,228 - 102,531,287 (+)EnsemblGRCm39 Ensembl
GRCm3812102,554,941 - 102,565,027 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12102,554,969 - 102,565,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712103,793,179 - 103,803,237 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612102,956,019 - 102,966,077 (+)NCBIMGSCv36mm8
Celera12103,769,159 - 103,779,238 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.66NCBI
Chga
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86127,460,895 - 127,472,238 (+)NCBIGRCr8
mRatBN7.26121,696,051 - 121,707,399 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6121,696,051 - 121,707,398 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6121,834,591 - 121,845,883 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,129,839 - 122,141,131 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06121,466,197 - 121,477,529 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06126,434,226 - 126,445,569 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6126,434,226 - 126,445,568 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06135,645,155 - 135,656,373 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.16126,825,283 - 126,836,311 (+)NCBI
Celera6119,184,838 - 119,196,152 (+)NCBICelera
RH 3.4 Map6845.4RGD
Cytogenetic Map6q32NCBI
Chga
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543815,092,394 - 15,104,381 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543815,092,267 - 15,104,321 (+)NCBIChiLan1.0ChiLan1.0
CHGA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21594,080,914 - 94,093,582 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11493,297,419 - 93,310,088 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01473,555,834 - 73,568,547 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11492,895,450 - 92,908,159 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1492,895,450 - 92,908,159 (+)Ensemblpanpan1.1panPan2
CHGA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.181,970,966 - 1,973,511 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha81,985,680 - 1,997,123 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.082,017,991 - 2,029,452 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.181,954,080 - 1,965,378 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.081,904,121 - 1,915,537 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.082,031,347 - 2,042,802 (+)NCBIUU_Cfam_GSD_1.0
Chga
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864012,539,821 - 12,551,315 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936733915,830 - 927,409 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936733915,700 - 927,220 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHGA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12470,663,040 - 70,675,827 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2470,663,298 - 70,677,116 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605357,912,590 - 57,924,715 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chga
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247349,404,916 - 9,416,902 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247349,405,121 - 9,416,774 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CHGA
404 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium 2 3 21
Low 8 2 1
Below cutoff 2 4 1 1

Sequence


RefSeq Acc Id: ENSSSCT00000002726   ⟹   ENSSSCP00000002657
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl7114,345,305 - 114,358,075 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000084306   ⟹   ENSSSCP00000072459
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl7114,345,091 - 114,358,571 (+)Ensembl
RefSeq Acc Id: NM_001164005   ⟹   NP_001157477
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.17114,345,542 - 114,357,799 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001157477 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA31016 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000002657
  ENSSSCP00000002657.3
GenBank Protein P04404 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001157477   ⟸   NM_001164005
- Peptide Label: precursor
- UniProtKB: A0A480ZDS7 (UniProtKB/TrEMBL),   A0A480Z7I2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000002657   ⟸   ENSSSCT00000002726
RefSeq Acc Id: ENSSSCP00000072459   ⟸   ENSSSCT00000084306


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002456 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000002726 ENTREZGENE
  ENSSSCT00000002726.5 UniProtKB/TrEMBL
InterPro Chromogranin_AB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chromogranin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Granin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene CHGA ENTREZGENE
PANTHER CHROMOGRANIN-A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10583 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Granin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS CHROMOGRANIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GRANINS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GRANINS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A480Z7I2 ENTREZGENE, UniProtKB/TrEMBL
  A0A480ZDS7 ENTREZGENE, UniProtKB/TrEMBL
  CMGA_PIG UniProtKB/Swiss-Prot
  F1SD66_PIG UniProtKB/TrEMBL
  P04404 ENTREZGENE
VGNC ID VGNC:103919 ENTREZGENE