TCTA (T cell leukemia translocation altered)

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Gene: TCTA (T cell leukemia translocation altered) Sus scrofa

Analyze

Symbol:

TCTA

Name:

T cell leukemia translocation altered

RGD ID:

14142630

Description:

INVOLVED IN negative regulation of osteoclast differentiation (inferred); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2P (ortholog); FOUND IN integral component of membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

T-cell leukemia translocation-altered gene protein

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	31,991,567 - 31,998,168 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	31,991,408 - 31,995,274 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive limb-girdle muscular dystrophy type 2P (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of osteoclast differentiation (IEA)

osteoclast fusion (IBA)

Cellular Component

integral component of membrane (IEA)

Molecular Function

protein binding (ISO)

References

Genomics

Comparative Map Data

TCTA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	31,991,567 - 31,998,168 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	31,991,408 - 31,995,274 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TCTA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	3	49,412,206 - 49,416,475 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	3	49,412,206 - 49,416,476 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	3	49,449,639 - 49,453,909 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	49,424,643 - 49,428,913 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	3	49,424,642 - 49,428,912	NCBI
Celera	3	49,414,426 - 49,418,696 (+)	NCBI
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	49,509,361 - 49,513,631 (+)	NCBI		HuRef
CHM1_1	3	49,402,406 - 49,406,676 (+)	NCBI		CHM1_1

Tcta
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	108,180,154 - 108,183,358 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	9	108,180,157 - 108,183,359 (-)	Ensembl
GRCm38	9	108,302,955 - 108,306,159 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	108,302,958 - 108,306,160 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	108,205,289 - 108,208,282 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	108,161,051 - 108,164,044 (-)	NCBI			mm8
Celera	9	107,912,001 - 107,914,995 (-)	NCBI		Celera
Cytogenetic Map	9	F2	NCBI
cM Map	9	59.2	NCBI

Tcta
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	108,988,588 - 108,992,324 (-)	NCBI
Rnor_6.0 Ensembl	8	117,079,095 - 117,082,162 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	8	117,079,094 - 117,082,338 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	8	116,427,898 - 116,431,164 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	8	108,291,610 - 108,294,678 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

Tcta
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	1,347,639 - 1,349,864 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955532	1,347,639 - 1,349,864 (+)	NCBI	ChiLan1.0	ChiLan1.0

TCTA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	50,584,614 - 50,588,891 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	3	49,340,010 - 49,344,288 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

TCTA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	20	39,822,211 - 39,824,200 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	20	39,820,845 - 39,824,526 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Tcta
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936529	1,045,735 - 1,047,922 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TCTA
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	10,809,342 - 10,813,655 (+)	NCBI
ChlSab1.1 Ensembl	22	10,809,595 - 10,812,029 (+)	Ensembl

Tcta
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	3,362,037 - 3,365,621 (+)	NCBI

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium			3			3		1
Low	10	4		5	2	20	2	2	3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021068738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021068739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSSSCT00000043143 ⟹ ENSSSCP00000044269

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	13	31,991,567 - 31,998,168 (+)	Ensembl

RefSeq Acc Id:

XM_021068738 ⟹ XP_020924397

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	13	31,991,411 - 31,995,274 (+)	NCBI

Sequence:

show sequence

ACTCATCCTTTAAGCAGGGTGGGGCTTGGTGCGCGTGCGCGGTTTTACTGCTCCGCCCCAACTG
CCAACTCTGCGCGCAGGCGAGGTAGGCGCTCCATGCCTCGGTTTACGCGTGCGCATTATTGAGT
CTGGCTCCGGAAGACCGGACGCTTGCGCAGTGGGGACTACGGTGACAGTCCCCTGGGTCCGCCA
CCGGCCAGTCATGGCGGAGCCTTGGTCGGGGCAGTCCTTGCAGGTTCTGCCGGCCACGGTGCTG
GGCGCGCTGGGCGCCCTCGGCAGCGAGTTCCTGCGGGAGTGGGAGGCTCAGGACATGCGCGTGA
CCCTCTTCAAGTTGCTGCTGCTTTGGTTGGTGTTAAGTCTCCTGAGCATCCAGCTGGCGTGGGG
GTTCTACGGGAGTACGGTGACCGGGCTGTATCACCGCCCAGCTCTGGATGTGTTCCTGCCCCCA
GGTCTGGGCAGCCAGAACGGATCCACACCTGATGGCTCCACGCATTTCTCGTCCTGGGAAACAG
CAGCAAATGAACCTCTCAAAACCCACAGAGAATAAGGGAAGGCAGCAAGAGGGGTCTCCAGGGA
CATCACCGGTTCTGCTACTGCCCAGACCCCAGGGACGACTGCAGAGGAGTAGGGGTTGGGGGGC
GGGGGGTACCCCAGTGCTGGCAGGCCTAGGCCTCCCCTGCCCTTGGCCTTGCCTCCAGCAGCCC
CAAGCCAGTAATTTGCCTCTACCTTTAGCTGGGTGCCTTAAGGAAAGGCATAATCCTCCTCTTT
CAGGGGTCAACTCAGAAGCCTCTGGGTTGGGATGACTAACAGTCCATTTTCTGTCTTGACTTTT
TCCTGGTCCTCTTCCCATCCCCTTGGGATGTGACCCCATAGAGATTTGTTCTTCTGAGAAGAAG
CCTGAGGTTGACCAACTCAGATTTGTAAGGCAAGTCTCTTTTCTCCTAAGTCCTGGGTTTTCCT
AAATTTCTTTGGTTTTGCTTTGTTGGCAGGGGGCCAGGGAATCCTGGCCTGGACACAGCTTTAT
ACTTTATGGTTACTTAGCTGGCCATCCAAGTACAAGGCAGGGGGCAGCTGGCACTCTCTACCCA
TGGAGAACATTGACCTCCCTTCGCCCATCCTGAGCTCTCCAGGTGGGAGGTGGGCAATGGAAGT
TGTCTTTTCCCAAGCATATTCTTTTCAGTCTCTCCCGGAAGGAAGCCAGGTGCCTGAAGGAGGC
TGAGTTCCCAAGGATGAGCCTCCATGCCCACTGCTTAAGTGCCCATGGGGTTGTGGATCTGTAC
CCTGCCCCTCACAAGGAGGTACTAAGGAGTTAGTGCAGAGAGGCCCCATCATGCCCTGTAGCCT
CACCACTTCCCATCTTGACCTGGAACCACAGCTTCATCCCAGAAGCCCACAGTCTCAGCTCCTC
CCCACTAGCACCACCTCAGCTCCCAAGAATTCTCAACAGGGAAGAGCCACAGGGTAGGCAGGCC
TACCACTTCCAGAGTGGGCCAAGGGAGCATCCAAAGGTATAAGTGGAACGCCAATTCCTGAAAG
CAGTGTGGCCCGAGACCTGTCTCCTTCCCTGATGGTCATATTTCTTCCTGCTTCTGCTGGGCCA
CCAGCTACCTCAGTGTCCCACTGCCTGCTTCCTCTTTGTTAAATGTCACATTTCCAGCTGGCAG
CCTTTGCCTAGGCCATCTTTGCAGAGTGCACTGGGGTAGAACTATGCTGAGCTCATGCACATGT
ACTCTGAAATATGTTCTAGCTGGTGGGATAATGCTTTTGTAGTCCCAGGCCCACCCACTAACGA
CACCACACTCAGCATCAGGGTCTCATATTTCACCCCAGGCTCAACTGAGGATGTGGCTTATTAA
ACATGGAAGTGCA

hide sequence

RefSeq Acc Id:

XM_021068739 ⟹ XP_020924398

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	13	31,991,408 - 31,995,274 (+)	NCBI

Sequence:

show sequence

GTCACTCATCCTTTAAGCAGGGTGGGGCTTGGTGCGCGTGCGCGGTTTTACTGCTCCGCCCCAA
CTGCCAACTCTGCGCGCAGGCGAGGTAGGCGCTCCATGCCTCGGTTTACGCGTGCGCATTATTG
AGTCTGGCTCCGGAAGACCGGACGCTTGCGCAGTGGGGACTACGGTGACAGTCCCCTGGGTCCG
CCACCGGCCAGTCATGGCGGAGCCTTGGTCGGGGCAGTCCTTGCAGGTTCTGCCGGCCACGGTG
CTGGGCGCGCTGGGCGCCCTCGGCAGCGAGTTCCTGCGGGAGTGGGAGGCTCAGGACATGCGCG
TGACCCTCTTCAAGTTGCTGCTGCTTTGGTTGGTGTTAAGTCTCCTGAGCATCCAGCTGGCGTG
GGGGTTCTACGGGAGTACGGTGACCGGGCTGTATCACCGCCCAGGTCTGGGCAGCCAGAACGGA
TCCACACCTGATGGCTCCACGCATTTCTCGTCCTGGGAAACAGCAGCAAATGAACCTCTCAAAA
CCCACAGAGAATAAGGGAAGGCAGCAAGAGGGGTCTCCAGGGACATCACCGGTTCTGCTACTGC
CCAGACCCCAGGGACGACTGCAGAGGAGTAGGGGTTGGGGGGCGGGGGGTACCCCAGTGCTGGC
AGGCCTAGGCCTCCCCTGCCCTTGGCCTTGCCTCCAGCAGCCCCAAGCCAGTAATTTGCCTCTA
CCTTTAGCTGGGTGCCTTAAGGAAAGGCATAATCCTCCTCTTTCAGGGGTCAACTCAGAAGCCT
CTGGGTTGGGATGACTAACAGTCCATTTTCTGTCTTGACTTTTTCCTGGTCCTCTTCCCATCCC
CTTGGGATGTGACCCCATAGAGATTTGTTCTTCTGAGAAGAAGCCTGAGGTTGACCAACTCAGA
TTTGTAAGGCAAGTCTCTTTTCTCCTAAGTCCTGGGTTTTCCTAAATTTCTTTGGTTTTGCTTT
GTTGGCAGGGGGCCAGGGAATCCTGGCCTGGACACAGCTTTATACTTTATGGTTACTTAGCTGG
CCATCCAAGTACAAGGCAGGGGGCAGCTGGCACTCTCTACCCATGGAGAACATTGACCTCCCTT
CGCCCATCCTGAGCTCTCCAGGTGGGAGGTGGGCAATGGAAGTTGTCTTTTCCCAAGCATATTC
TTTTCAGTCTCTCCCGGAAGGAAGCCAGGTGCCTGAAGGAGGCTGAGTTCCCAAGGATGAGCCT
CCATGCCCACTGCTTAAGTGCCCATGGGGTTGTGGATCTGTACCCTGCCCCTCACAAGGAGGTA
CTAAGGAGTTAGTGCAGAGAGGCCCCATCATGCCCTGTAGCCTCACCACTTCCCATCTTGACCT
GGAACCACAGCTTCATCCCAGAAGCCCACAGTCTCAGCTCCTCCCCACTAGCACCACCTCAGCT
CCCAAGAATTCTCAACAGGGAAGAGCCACAGGGTAGGCAGGCCTACCACTTCCAGAGTGGGCCA
AGGGAGCATCCAAAGGTATAAGTGGAACGCCAATTCCTGAAAGCAGTGTGGCCCGAGACCTGTC
TCCTTCCCTGATGGTCATATTTCTTCCTGCTTCTGCTGGGCCACCAGCTACCTCAGTGTCCCAC
TGCCTGCTTCCTCTTTGTTAAATGTCACATTTCCAGCTGGCAGCCTTTGCCTAGGCCATCTTTG
CAGAGTGCACTGGGGTAGAACTATGCTGAGCTCATGCACATGTACTCTGAAATATGTTCTAGCT
GGTGGGATAATGCTTTTGTAGTCCCAGGCCCACCCACTAACGACACCACACTCAGCATCAGGGT
CTCATATTTCACCCCAGGCTCAACTGAGGATGTGGCTTATTAAACATGGAAGTGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020924397	(Get FASTA)	NCBI Sequence Viewer
	XP_020924398	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	XP_020924398 ⟸ XM_021068739
- Peptide Label:	isoform X2
- Sequence:	show sequence MAEPWSGQSLQVLPATVLGALGALGSEFLREWEAQDMRVTLFKLLLLWLVLSLLSIQLAWGFYG STVTGLYHRPGLGSQNGSTPDGSTHFSSWETAANEPLKTHRE hide sequence

RefSeq Acc Id:	XP_020924397 ⟸ XM_021068738
- Peptide Label:	isoform X1
- Sequence:	show sequence MAEPWSGQSLQVLPATVLGALGALGSEFLREWEAQDMRVTLFKLLLLWLVLSLLSIQLAWGFYG STVTGLYHRPALDVFLPPGLGSQNGSTPDGSTHFSSWETAANEPLKTHRE hide sequence

RefSeq Acc Id:

ENSSSCP00000044269 ⟸ ENSSSCT00000043143

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000037459	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00070003838	UniProtKB/TrEMBL
Ensembl Protein	ENSSSCP00000044269	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCP00070005880	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000043143	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCT00070007185	UniProtKB/TrEMBL
InterPro	TCTA	UniProtKB/TrEMBL
NCBI Gene	TCTA	ENTREZGENE
PANTHER	PTHR32267	UniProtKB/TrEMBL
Pfam	T_cell_tran_alt	UniProtKB/TrEMBL
PIRSF	TCTA	UniProtKB/TrEMBL
UniProt	A0A287AK43_PIG	UniProtKB/TrEMBL
	A0A4X1SSR7_PIG	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar