TTL (tubulin tyrosine ligase) - Rat Genome Database

Name: TTL
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: TTL (tubulin tyrosine ligase) Sus scrofa

Analyze

Symbol:

TTL

Name:

tubulin tyrosine ligase

RGD ID:

14138075

Description:

ENCODES a protein that exhibits tubulin-tyrosine ligase activity (ortholog); INVOLVED IN microtubule cytoskeleton organization (ortholog); positive regulation of mitotic cell cycle (ortholog); post-translational protein modification (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN spindle microtubule (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

tubulin--tyrosine ligase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TTL (tubulin tyrosine ligase)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Ttl (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ttl (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ttl (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TTL (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TTL (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ttl (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TTL (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ttl (tubulin tyrosine ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	43,977,265 - 44,022,635 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	43,980,634 - 44,022,611 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	45,574,533 - 45,617,612 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

microtubule cytoskeleton organization (IBA,IEA,ISO)

positive regulation of mitotic cell cycle (ISO)

post-translational protein modification (ISO)

protein modification process (IEA)

regulation of axon extension (ISO)

regulation of metaphase plate congression (ISO)

Cellular Component

spindle microtubule (IBA,IEA)

Molecular Function

ATP binding (IEA)

ligase activity (IEA)

tubulin-tyrosine ligase activity (IBA,IEA,ISO)

References

Additional References at PubMed

PMID:8093886	PMID:22301074

Genomics

Comparative Map Data

TTL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	43,977,265 - 44,022,635 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	43,980,634 - 44,022,611 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	45,574,533 - 45,617,612 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TTL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	112,482,156 - 112,541,739 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	112,482,156 - 112,541,739 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	113,239,733 - 113,299,316 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	112,956,214 - 113,006,694 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	112,956,128 - 113,006,212	NCBI
Celera	2	106,625,279 - 106,675,764 (+)	NCBI		Celera
Cytogenetic Map	2	q14.1	NCBI
HuRef	2	105,693,725 - 105,744,724 (+)	NCBI		HuRef
CHM1_1	2	113,243,890 - 113,294,368 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	112,908,795 - 112,968,389 (+)	NCBI		T2T-CHM13v2.0

Ttl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	128,907,867 - 128,938,203 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	128,907,862 - 128,938,203 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	129,065,947 - 129,096,283 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	129,065,942 - 129,096,283 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	128,891,683 - 128,922,019 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	128,757,430 - 128,785,190 (+)	NCBI		MGSCv36	mm8
Celera	2	130,293,491 - 130,323,607 (+)	NCBI		Celera
Cytogenetic Map	2	F1	NCBI
cM Map	2	62.65	NCBI

Ttl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	136,752,025 - 136,781,758 (+)	NCBI		GRCr8
mRatBN7.2	3	116,298,813 - 116,328,538 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	116,298,797 - 116,328,538 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	120,196,066 - 120,222,520 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	128,791,655 - 128,818,105 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	126,452,127 - 126,478,585 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	121,596,773 - 121,626,581 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	121,596,791 - 121,624,048 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	128,388,189 - 128,417,974 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	116,671,419 - 116,697,989 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	116,576,991 - 116,603,562 (+)	NCBI
Celera	3	115,124,248 - 115,150,813 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

Ttl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955470	1,743,751 - 1,774,512 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955470	1,747,217 - 1,774,512 (-)	NCBI	ChiLan1.0	ChiLan1.0

TTL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	15,591,253 - 15,632,233 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	15,594,017 - 15,635,068 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	89,526,022 - 89,567,068 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	113,505,416 - 113,546,896 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	113,505,416 - 113,546,896 (+)	Ensembl	panpan1.1		panPan2

TTL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	36,735,836 - 36,770,292 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	36,735,788 - 36,767,016 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	36,504,890 - 36,539,300 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	37,511,436 - 37,545,848 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	37,511,409 - 37,545,835 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	36,649,169 - 36,683,745 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	36,703,448 - 36,738,023 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	36,917,312 - 36,951,900 (+)	NCBI		UU_Cfam_GSD_1.0

Ttl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	82,096,219 - 82,130,048 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936783	989,269 - 1,025,690 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936783	989,269 - 1,024,537 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TTL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	15,500,417 - 15,540,252 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	15,500,520 - 15,538,184 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666080	4,140,168 - 4,186,856 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ttl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624749	12,549,969 - 12,595,490 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624749	12,550,017 - 12,595,397 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in TTL
1135 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium						8
Low	10	4	3	5	2	15	2	3	3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001004041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001307533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK240318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01034639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X68453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000008870 ⟹ ENSSSCP00000008644

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	43,977,111 - 44,022,524 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000044871 ⟹ ENSSSCP00000040869

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	43,978,914 - 44,022,535 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000084504 ⟹ ENSSSCP00000068994

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	43,977,266 - 44,022,635 (-)	Ensembl

RefSeq Acc Id:

NM_001004041 ⟹ NP_001004041

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	3	43,980,634 - 44,022,611 (-)	NCBI

Sequence:

show sequence

GCGGCCGGCTACCCTAGAAGCGTGAGGGCGGGCGCCCAGGCCGCTGGCGGGGGCGCGGCTGGAG
CGTGTGGGGCGGGGCCGGCGGGGCCGACGGGTCGGGAGCGCGGCAGTCGCCCCGGCTGGTCCCA
CGCTGAGCAGCGCTTGGCCGGCTGTTTCCTGCAGCGGCTGCAGGGGTGGCCCCGGCGCGCGGCC
CTTCACCATGTACACCTTCGTGGTGCGCGACGAGAACAGCAGCGTTTACGCCGAGGTCTCCCGG
CTGCTGCTCGCCACCGGCCACTGGAAGAGGCTACGGCGGGACAATCCCAGGTTCAACCTGATGC
TGGGAGAAAGGAACCGGCTGCCCTTCGGGAGACTGGGTCACGAGCCTGGATTGATGCAGTTGGT
GAATTACTACCGGGGCGCCGACAAACTGTGTCGCAAAGCTTCCTTAGTGAAGCTCATCAAGACC
AGCCCAGAACTGGCTGAGTCCTGCACGTGGTTCCCGGAGTCCTATGTGATTTATCCAACTAACC
TCAAGACCCCAGTTGCTCCAGCTCAGAATGGAATCCACCCACCAATCCACAGCTCCAGGACAGA
TGAAAGAGAATTTTTCCTGACTTCTTACAACAAAAAGAAAGAAGATGGAGAGGGCAATGTTTGG
ATTGCAAAGTCATCGGCTGGAGCCAAAGGTGAAGGCATCCTCATCTCCTCAGAGGCTACAGAGC
TGCTGGATTTCATAGACAACCAGGGCCAGGTGCACGTGATCCAGAAGTACCTTGAGCGCCCTCT
GCTGCTGGAGCCAGGCCATCGCAAGTTTGACATCAGAAGCTGGGTCTTGGTGGATCATCAGTAT
AACATCTACCTCTACAGAGAAGGTGTGCTTCGGACTGCTTCAGAACCGTACCATACAGATAATT
TCCAAGACAAAACCTGCCATTTGACCAATCACTGCATTCAGAAGGAGTACTCGAAGAATTATGG
AAAGTATGAAGAAGGGAATGAAATGTTCTTTGAGGAGTTCAATCAGTACCTCACAAGTGCTTTG
AACATTACCCTGGAAAGTAGTATCTTACTACAAATCAAACATATAATAAGGAGCTGCCTCCTGA
GCGTGGAGCCCGCCATCAGCACCCGGCACCTGCCTTACCAGAGCTTCCAGCTCTTCGGCTTCGA
CTTCATGGTGGATGAGGACCTGAAGGTGTGGCTCATCGAAGTCAACGGCGCCCCGGCTTGTGCT
CAGAAGCTCTACGCTGAGCTGTGTCAAGGCATCGTGGACATAGCCATAGCCAGTGTCTTCCCGC
CCCCGGATGCAGAGCAGCAGCAGCAGCAGCCCCCGCCGGCCGCTTTCATCAAGCTATGACCGAG
GGAGGTGCCCCGAGCTGCCTTGGAAGAAGCAGGAGGGGGCCCTGGCGGGGAAGGAGAAACCAAG
CCAAACAGGAGGAAGAGCAGCAACTTGCAGAGACACGACCATAGAAGAACAGGCAGCTTCCCTG
AGGAACAGGCAGCTTCCCTGAGGAGTGGTCACCCAGGGTTTCTGGGTGTCGCGCTCAGCACTGC
TACTGAGATTCAAAACCGAAACAAATTTCTCTAAGGAGAGAGCAAGCGGCCGC

hide sequence

RefSeq Acc Id:

XR_001307533

Type:

NON-CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	3	43,980,856 - 44,022,536 (-)	NCBI

Sequence:

show sequence

GGGGCCGGCGGGGCCGACGGGTCGGGAGCGCGGCAGTCGCCCCGGCTGGTCCCACGCTGAGCAG
CCGCTTGGCCGGCTGTTTCCTGCAGCGGCTGCAGGGGTGGCCCCGGCGCGCGGCCCTTCACCAT
GTACACCTTCGTGGTGCGCGACGAGAACAGCAGCGTTTACGCCGAGGTCTCCCGGCTGCTGCTC
GCCACCGGCCACTGGAAGAGGCTACGGCGGGACAATCCCAGGTTCAACCTGATGCTGGGAGAAA
GGAACCGGCTGCCCTTCGGGAGACTGGGTCACGAGCCTGGATTGATGCAGTTGGTGAATTACTA
CCGGGGCGCCGACAAACTGTGTCGCAAAGCTTCCTTAGTGAAGCTCATCAAGACCAGCCCAGAA
CTGGCTGAGTCCTGCACGTGGTTCCCGGAGTCCTATGTGATTTATCCAACTAACCTCAAGACCC
CAGTTGCTCCAGCTCAGAATGGAATCCACCCACCAATCCACAGCTCCAGGACAGATGAAAGAGA
ATTTTTCCTTACTTCTTACAACAAAAAGAAAGAAGATGGAGAGGGCAATGTTTGGATTGCAAAG
TCATCGGCTGGAGCCAAAGGTGAAGGCATCCTCATCTCCTCAGAGGCTACAGAGCTGCTGGATT
TCATAGACAACCAGGGCCAGGTGCACGTGATCCAGAAGTACCTTGAGCGCCCTCTGCTGCTGGA
GCCAGGCCATCGCAAGTTTGACATCAGAAGCTGGGTCTTGGTGGATCATCAGTATAACATCTAC
CTCTACAGAGAAGGTGTGCTTCGGACTGCTTCAGAACCGTACCATACAGATAATTTCCAAGACA
AAACCTGCCATTTGACCAATCACTGCATTCAGAAGGAGTACTCGAAGAATTATGGAAAGTATGA
AGAAGGGAATGAAATGTTCTTTGAGGAGTTCAATCAGTACCTCACAAGTGCTTTGAACATTACC
CTGGAAAGTAGTATCTTACTACAAATCAAACATATAATAAGGAGCTGCCTCCTGAGCGTGGAGC
CCGCCATCAGCACCCGGCACCTGCCTTACCAGAGCTTCCAGCTCTTCGGCTTCGACTTCATGGT
GGATGAGGACCTGAAGGTGTGGCTCATCGAAGTCAACGGCGCCCCTGCTTGTGCTCAGCTGTTG
GTTCTTCTGAAGATCCACGTTCATCAATGTCGAGACCCTCTCATGGCTCCCCACGTCCACGTCT
TGGAGAAATCGAGGTGATTTTCCAGCGGTGTAGGAGAAAGGCCTGTACCTCCAAGGGGCAGTGT
TAACACATAAGTGGTGCCCTCCCTGGGAGCCAGGCCTTTGCCTCTTGCTTCATGGCTGTGACAG
ACAGGAAGCTCTACGCTGAGCTGTGCCAGGGCATCGTGGACATAGCCATAGCCAGTGTCTTCCC
GCCCCCGGATGCAGAGCAGCAGCAGCAGCAGCCCCCGCCGGCCGCTTTCATCAAGCTATGACCG
AGGGAG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001004041	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAA48494	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000008644
	ENSSSCP00000008644.3
	ENSSSCP00000008644.4
	ENSSSCP00000040869.2
	ENSSSCP00025002037.1
	ENSSSCP00045023389.1
	ENSSSCP00050046153.1
	ENSSSCP00065037402.1
	ENSSSCP00070038207.1
	ENSSSCP00070038235.1
	ENSSSCP00070038290.1
GenBank Protein	P38160	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001004041 ⟸ NM_001004041

- UniProtKB:

P38160 (UniProtKB/Swiss-Prot), A0A481CF77 (UniProtKB/TrEMBL), A0A5S6G4E5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYTFVVRDENSSVYAEVSRLLLATGHWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLMQLVNY
YRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIHPPIHSSRTDER
EFFLTSYNKKKEDGEGNVWIAKSSAGAKGEGILISSEATELLDFIDNQGQVHVIQKYLERPLLL
EPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHTDNFQDKTCHLTNHCIQKEYSKNYGKY
EEGNEMFFEEFNQYLTSALNITLESSILLQIKHIIRSCLLSVEPAISTRHLPYQSFQLFGFDFM
VDEDLKVWLIEVNGAPACAQKLYAELCQGIVDIAIASVFPPPDAEQQQQQPPPAAFIKL

hide sequence

RefSeq Acc Id:

ENSSSCP00000040869 ⟸ ENSSSCT00000044871

RefSeq Acc Id:

ENSSSCP00000068994 ⟸ ENSSSCT00000084504

RefSeq Acc Id:

ENSSSCP00000008644 ⟸ ENSSSCT00000008870

Protein Domains

TTL

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000008097	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSSSCG00025003981	UniProtKB/Swiss-Prot
	ENSSSCG00045019764	UniProtKB/Swiss-Prot
	ENSSSCG00050076474	UniProtKB/Swiss-Prot
	ENSSSCG00065062368	UniProtKB/Swiss-Prot
	ENSSSCG00070022661	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000008870	ENTREZGENE
	ENSSSCT00000008870.4	UniProtKB/TrEMBL
	ENSSSCT00000008870.5	UniProtKB/Swiss-Prot
	ENSSSCT00000044871.2	UniProtKB/TrEMBL
	ENSSSCT00025005277.1	UniProtKB/Swiss-Prot
	ENSSSCT00045033729.1	UniProtKB/Swiss-Prot
	ENSSSCT00050105059.1	UniProtKB/Swiss-Prot
	ENSSSCT00065085571.1	UniProtKB/Swiss-Prot
	ENSSSCT00070045327.1	UniProtKB/Swiss-Prot
	ENSSSCT00070045357.1	UniProtKB/TrEMBL
	ENSSSCT00070045424.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.11480	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ATP-grasp fold, B domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	TTL/TTLL_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	ssc:445530	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	TTL	ENTREZGENE
PANTHER	TUBULIN--TYROSINE LIGASE	UniProtKB/Swiss-Prot
	TUBULIN--TYROSINE LIGASE	UniProtKB/Swiss-Prot
	TUBULIN--TYROSINE LIGASE	UniProtKB/TrEMBL
	TUBULIN--TYROSINE LIGASE	UniProtKB/TrEMBL
Pfam	TTL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	TTL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Glutathione synthetase ATP-binding domain-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A287AAQ3_PIG	UniProtKB/TrEMBL
	A0A481CF77	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1V654_PIG	UniProtKB/TrEMBL
	A0A4X1VAE5_PIG	UniProtKB/TrEMBL
	A0A5S6G4E5	ENTREZGENE, UniProtKB/TrEMBL
	P38160	ENTREZGENE, UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

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Imported Disease Annotations - ClinVar