HEXB (hexosaminidase subunit beta) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: HEXB (hexosaminidase subunit beta) Sus scrofa
Analyze
Symbol: HEXB
Name: hexosaminidase subunit beta
RGD ID: 14137222
Description: ENCODES a protein that exhibits beta-N-acetylglucosaminidase activity (ortholog); beta-N-acetylhexosaminidase activity (ortholog); carbohydrate binding (ortholog); INVOLVED IN cellular calcium ion homeostasis (ortholog); cellular protein metabolic process (ortholog); ganglioside catabolic process (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN beta-N-acetylhexosaminidase complex (ortholog); cortical granule (ortholog); lysosome (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 65 kDa epididymal boar protein; beta-hexosaminidase subunit beta; beta-N-acetylhexosaminidase subunit beta; hexosaminidase subunit B; N-acetyl-beta-glucosaminidase subunit beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl283,744,627 - 83,784,759 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1283,745,263 - 83,784,762 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,331,866 - 85,371,568 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:8902205   PMID:14681463  


Genomics

Comparative Map Data
HEXB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl283,744,627 - 83,784,759 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1283,745,263 - 83,784,762 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,331,866 - 85,371,568 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HEXB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl574,640,023 - 74,722,647 (+)EnsemblGRCh38hg38GRCh38
GRCh38574,640,023 - 74,721,288 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37573,935,848 - 74,017,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,016,767 - 74,052,869 (+)NCBINCBI36hg18NCBI36
Build 34574,016,766 - 74,052,869NCBI
Celera569,875,759 - 69,911,869 (+)NCBI
Cytogenetic Map5q13.3NCBI
HuRef569,185,979 - 69,222,054 (+)NCBIHuRef
CHM1_1573,413,670 - 73,449,974 (+)NCBICHM1_1
Hexb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391397,312,839 - 97,334,865 (-)NCBIGRCm39mm39
GRCm39 Ensembl1397,312,839 - 97,334,865 (-)Ensembl
GRCm381397,176,331 - 97,198,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1397,176,331 - 97,198,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv371397,946,286 - 97,968,312 (-)NCBIGRCm37mm9NCBIm37
MGSCv361398,277,106 - 98,298,969 (-)NCBImm8
Celera13100,809,364 - 100,830,755 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.66NCBI
Hexb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2228,483,997 - 28,504,165 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl228,484,012 - 28,504,223 (-)Ensembl
Rnor_6.0227,983,925 - 28,003,260 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,984,117 - 28,003,186 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0247,094,814 - 47,114,992 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,649,188 - 27,672,231 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1227,569,557 - 27,592,600 (-)NCBI
Celera224,525,921 - 24,545,955 (-)NCBICelera
Cytogenetic Map2q12NCBI
Hexb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,942,278 - 25,961,312 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,942,341 - 25,961,312 (-)NCBIChiLan1.0ChiLan1.0
HEXB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1541,199,681 - 41,232,693 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl541,199,681 - 41,232,693 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0540,589,448 - 40,625,176 (-)NCBIMhudiblu_PPA_v0panPan3
HEXB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1257,221,809 - 57,248,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl257,222,186 - 57,248,417 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,199,623 - 54,228,736 (+)NCBI
ROS_Cfam_1.0257,746,022 - 57,775,171 (+)NCBI
UMICH_Zoey_3.1254,810,104 - 54,839,238 (+)NCBI
UNSW_CanFamBas_1.0255,573,246 - 55,602,349 (+)NCBI
UU_Cfam_GSD_1.0256,470,393 - 56,499,556 (+)NCBI
Hexb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213188,915,295 - 188,940,491 (+)NCBI
SpeTri2.0NW_0049365491,918,482 - 1,943,665 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HEXB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,037,532 - 69,065,925 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl469,037,583 - 69,065,814 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604917,815,486 - 17,843,814 (+)NCBIVero_WHO_p1.0
Hexb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624924195,406 - 219,232 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 2 3 5 3 2 3 3
Low 2 2 2 20
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000015373   ⟹   ENSSSCP00000014965
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl283,745,246 - 83,784,756 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000042967   ⟹   ENSSSCP00000032030
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl283,744,627 - 83,784,759 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000048299   ⟹   ENSSSCP00000040410
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl283,745,292 - 83,784,756 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000051525   ⟹   ENSSSCP00000036716
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl283,745,246 - 83,784,756 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000052645   ⟹   ENSSSCP00000056891
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl283,745,336 - 83,784,756 (+)Ensembl
RefSeq Acc Id: NM_213921   ⟹   NP_999086
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1283,745,263 - 83,784,762 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_999086 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAI47712 (Get FASTA)   NCBI Sequence Viewer  
  CAA63123 (Get FASTA)   NCBI Sequence Viewer  
  Q29548 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_999086   ⟸   NM_213921
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: ENSSSCP00000014965   ⟸   ENSSSCT00000015373
RefSeq Acc Id: ENSSSCP00000036716   ⟸   ENSSSCT00000051525
RefSeq Acc Id: ENSSSCP00000032030   ⟸   ENSSSCT00000042967
RefSeq Acc Id: ENSSSCP00000056891   ⟸   ENSSSCT00000052645
RefSeq Acc Id: ENSSSCP00000040410   ⟸   ENSSSCT00000048299
Protein Domains
Glyco_hydro_20   Glycohydro_20b2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014073 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070002597 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000014965 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000032030 UniProtKB/TrEMBL
  ENSSSCP00000036716 UniProtKB/TrEMBL
  ENSSSCP00000040410 UniProtKB/TrEMBL
  ENSSSCP00000056891 UniProtKB/TrEMBL
  ENSSSCP00070003998 UniProtKB/TrEMBL
  ENSSSCP00070004006 UniProtKB/TrEMBL
  ENSSSCP00070004016 UniProtKB/TrEMBL
  ENSSSCP00070004022 UniProtKB/TrEMBL
  ENSSSCP00070004030 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000015373 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000042967 UniProtKB/TrEMBL
  ENSSSCT00000048299 UniProtKB/TrEMBL
  ENSSSCT00000051525 UniProtKB/TrEMBL
  ENSSSCT00000052645 UniProtKB/TrEMBL
  ENSSSCT00070004914 UniProtKB/TrEMBL
  ENSSSCT00070004922 UniProtKB/TrEMBL
  ENSSSCT00070004933 UniProtKB/TrEMBL
  ENSSSCT00070004940 UniProtKB/TrEMBL
  ENSSSCT00070004949 UniProtKB/TrEMBL
Gene3D-CATH 3.30.379.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Beta_hexosaminidase_sua/sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_20_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hex-like_dom2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEX_eukaryotic_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:396958 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene HEXB ENTREZGENE
Pfam Glyco_hydro_20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycohydro_20b2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF B-hxosamndse_ab_euk UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
PRINTS GLHYDRLASE20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55545 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286ZKQ1_PIG UniProtKB/TrEMBL
  A0A286ZYC3_PIG UniProtKB/TrEMBL
  A0A287A956_PIG UniProtKB/TrEMBL
  A0A287BKF8_PIG UniProtKB/TrEMBL
  A0A4X1SN32_PIG UniProtKB/TrEMBL
  A0A4X1SN58_PIG UniProtKB/TrEMBL
  A0A4X1SPP3_PIG UniProtKB/TrEMBL
  A0A4X1SPQ4_PIG UniProtKB/TrEMBL
  A0A4X1SPQ9_PIG UniProtKB/TrEMBL
  D0G6X8_PIG UniProtKB/TrEMBL
  HEXB_PIG UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary F1S2J8 UniProtKB/TrEMBL
VGNC ID VGNC:88861 ENTREZGENE