FCAR (Fc alpha receptor) - Rat Genome Database

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Gene: FCAR (Fc alpha receptor) Sus scrofa
Analyze
Symbol: FCAR
Name: Fc alpha receptor
RGD ID: 14137208
Description: ENCODES a protein that exhibits IgA binding (ortholog); IgA receptor activity (ortholog); INVOLVED IN cellular response to granulocyte macrophage colony-stimulating factor stimulus (ortholog); cellular response to interferon-alpha (ortholog); cellular response to interleukin-6 (ortholog); ASSOCIATED WITH genetic disease (ortholog); granulomatosis with polyangiitis (ortholog); IgA glomerulonephritis (ortholog); FOUND IN plasma membrane (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fc fragment of IgA receptor; Fc fragment of IgA, receptor for; immunoglobulin A Fc fragment receptor; immunoglobulin alpha Fc receptor
RGD Orthologs
Human
Rat
Bonobo
Dog
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,074,996 - 59,084,788 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,074,979 - 59,084,798 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2653,998,651 - 54,008,044 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:27586529  


Genomics

Comparative Map Data
FCAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,074,996 - 59,084,788 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,074,979 - 59,084,798 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2653,998,651 - 54,008,044 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FCAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381954,874,235 - 54,891,420 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1954,874,235 - 54,891,420 (+)EnsemblGRCh38hg38GRCh38
GRCh371955,385,691 - 55,402,786 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,077,361 - 60,093,651 (+)NCBINCBI36Build 36hg18NCBI36
Build 341960,077,360 - 60,092,249NCBI
Celera1952,426,154 - 52,442,442 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1951,708,188 - 51,724,488 (+)NCBIHuRef
CHM1_11955,379,113 - 55,395,493 (+)NCBICHM1_1
T2T-CHM13v2.01957,968,550 - 57,985,728 (+)NCBIT2T-CHM13v2.0
Fcar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2169,626,458 - 69,660,558 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx174,985,346 - 75,019,443 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0183,549,652 - 83,583,756 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0176,707,876 - 76,741,999 (-)NCBIRnor_WKY
Rnor_6.0173,230,392 - 73,263,462 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl173,230,390 - 73,264,302 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0175,285,444 - 75,318,514 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4168,976,542 - 69,022,651 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1169,054,652 - 69,100,762 (-)NCBI
Celera167,474,424 - 67,508,554 (+)NCBICelera
Cytogenetic Map1q12NCBI
FCAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11960,614,350 - 60,630,614 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1960,614,405 - 60,630,480 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01951,919,345 - 51,935,340 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FCAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,709,675 - 102,720,680 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1102,773,321 - 102,784,329 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01103,376,217 - 103,387,212 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11102,995,899 - 103,006,891 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,700,005 - 102,711,007 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,472,232 - 103,483,230 (-)NCBIUU_Cfam_GSD_1.0
LOC103235282
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1647,498,332 - 47,512,629 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl647,498,497 - 47,514,417 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604532,031 - 48,396 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system respiratory system
High
Medium 2
Low 3 1 1 2 1
Below cutoff 5 1 2 3 5 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000003648   ⟹   ENSSSCP00000003563
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl659,074,996 - 59,084,788 (+)Ensembl
RefSeq Acc Id: NM_001123112   ⟹   NP_001116584
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1659,074,996 - 59,084,350 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003481905   ⟹   XP_003481953
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1659,074,979 - 59,084,798 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001116584 (Get FASTA)   NCBI Sequence Viewer  
  XP_003481953 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AEL12459 (Get FASTA)   NCBI Sequence Viewer  
  CAN13343 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003481953   ⟸   XM_003481905
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001116584   ⟸   NM_001123112
- Peptide Label: precursor
- UniProtKB: K7GP65 (UniProtKB/TrEMBL),   A0A0B4J2J3 (UniProtKB/TrEMBL),   A0A4X1VI73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000003563   ⟸   ENSSSCT00000003648
Protein Domains
Immunoglobulin subtype


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000003284 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005006108 UniProtKB/TrEMBL
  ENSSSCG00015003325 UniProtKB/TrEMBL
  ENSSSCG00025065642 UniProtKB/TrEMBL
  ENSSSCG00030022705 UniProtKB/TrEMBL
  ENSSSCG00035052975 UniProtKB/TrEMBL
  ENSSSCG00040062327 UniProtKB/TrEMBL
  ENSSSCG00045035457 UniProtKB/TrEMBL
  ENSSSCG00050065256 UniProtKB/TrEMBL
  ENSSSCG00055015041 UniProtKB/TrEMBL
  ENSSSCG00060045478 UniProtKB/TrEMBL
  ENSSSCG00065006199 UniProtKB/TrEMBL
  ENSSSCG00070024624 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000003563 ENTREZGENE
  ENSSSCP00000003563.3 UniProtKB/TrEMBL
  ENSSSCP00005005494.1 UniProtKB/TrEMBL
  ENSSSCP00015001498.1 UniProtKB/TrEMBL
  ENSSSCP00025039452.1 UniProtKB/TrEMBL
  ENSSSCP00030014172.1 UniProtKB/TrEMBL
  ENSSSCP00035028677.1 UniProtKB/TrEMBL
  ENSSSCP00040037054.1 UniProtKB/TrEMBL
  ENSSSCP00045042767.1 UniProtKB/TrEMBL
  ENSSSCP00050038158.1 UniProtKB/TrEMBL
  ENSSSCP00055023606.1 UniProtKB/TrEMBL
  ENSSSCP00060026414.1 UniProtKB/TrEMBL
  ENSSSCP00065003531.1 UniProtKB/TrEMBL
  ENSSSCP00070041527.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000003648 ENTREZGENE
  ENSSSCT00000003648.3 UniProtKB/TrEMBL
  ENSSSCT00005009253.1 UniProtKB/TrEMBL
  ENSSSCT00015004219.1 UniProtKB/TrEMBL
  ENSSSCT00025090083.1 UniProtKB/TrEMBL
  ENSSSCT00030031515.1 UniProtKB/TrEMBL
  ENSSSCT00035070659.1 UniProtKB/TrEMBL
  ENSSSCT00040084856.1 UniProtKB/TrEMBL
  ENSSSCT00045060889.1 UniProtKB/TrEMBL
  ENSSSCT00050088888.1 UniProtKB/TrEMBL
  ENSSSCT00055029659.1 UniProtKB/TrEMBL
  ENSSSCT00060061684.1 UniProtKB/TrEMBL
  ENSSSCT00065008338.1 UniProtKB/TrEMBL
  ENSSSCT00070049168.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
KEGG Report ssc:100144539 UniProtKB/TrEMBL
NCBI Gene FCAR ENTREZGENE
PANTHER IMMUNOGLOBULIN ALPHA FC RECEPTOR UniProtKB/TrEMBL
  MHC CLASS I NK CELL RECEPTOR UniProtKB/TrEMBL
Pfam PF00047 UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0B4J2J3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VI73 ENTREZGENE, UniProtKB/TrEMBL
  K7GP65 ENTREZGENE
VGNC ID VGNC:88059 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-11-08 FCAR  Fc alpha receptor  FCAR  Fc fragment of IgA receptor  Symbol and/or name change 19259463 PROVISIONAL