ACO2 (aconitase 2) - Rat Genome Database

Name: ACO2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: ACO2 (aconitase 2) Sus scrofa

Analyze

Symbol:

ACO2

Name:

aconitase 2

RGD ID:

14135229

Description:

ENCODES a protein that exhibits 3 iron, 4 sulfur cluster binding (ortholog); 4 iron, 4 sulfur cluster binding (ortholog); aconitate hydratase activity (ortholog); INVOLVED IN citrate metabolic process (ortholog); isocitrate metabolic process (ortholog); liver development (ortholog); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria pathway; mitochondrial complex II deficiency pathway; ASSOCIATED WITH acute intermittent porphyria (ortholog); adenylosuccinase lyase deficiency (ortholog); adult respiratory distress syndrome (ortholog); FOUND IN mitochondrial matrix (ortholog); INTERACTS WITH curcumin; maleic acid

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

aconitate hydratase, mitochondrial; citrate hydro-lyase; heart aconitase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACO2 (aconitase 2)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Aco2 (aconitase 2, mitochondrial)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Aco2 (aconitase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Aco2 (aconitase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACO2 (aconitase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACO2 (aconitase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Aco2 (aconitase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACO2 (aconitase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Aco2 (aconitase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	7,008,719 - 7,071,025 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	7,014,383 - 7,071,023 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	4,385,951 - 4,443,595 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute intermittent porphyria (ISO)

adenylosuccinase lyase deficiency (ISO)

adult respiratory distress syndrome (ISO)

common variable immunodeficiency 4 (ISO)

COVID-19 (ISO)

Developmental Disabilities (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

infantile cerebellar-retinal degeneration (ISO)

mitochondrial metabolism disease (ISO)

optic atrophy 9 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

curcumin (EXP)

maleic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

citrate metabolic process (IEA,ISO)

isocitrate metabolic process (ISO)

liver development (ISO)

response to isolation stress (ISO)

tricarboxylic acid cycle (IBA,IEA,ISO)

Cellular Component

cytosol (IBA,IEA)

mitochondrial matrix (IEA,ISO)

mitochondrion (IBA,IEA)

Molecular Function

3 iron, 4 sulfur cluster binding (ISO)

4 iron, 4 sulfur cluster binding (IBA,IEA,ISO)

aconitate hydratase activity (IBA,IEA,ISO)

iron ion binding (IEA)

lyase activity (IEA)

metal ion binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

citric acid cycle pathway (ISO)

fumaric aciduria pathway (ISO)

mitochondrial complex II deficiency pathway (ISO)

pyruvate dehydrogenase E2 deficiency pathway (ISO)

pyruvate dehydrogenase E3 deficiency pathway (ISO)

References

Additional References at PubMed

PMID:2303429	PMID:2726740	PMID:2798408	PMID:8661698	PMID:10631981	PMID:14681463	PMID:16142896	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ACO2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	7,008,719 - 7,071,025 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	7,014,383 - 7,071,023 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	4,385,951 - 4,443,595 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACO2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	41,469,117 - 41,528,974 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	41,447,830 - 41,529,273 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	41,865,121 - 41,924,978 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	40,195,075 - 40,254,939 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	40,189,628 - 40,249,492	NCBI
Celera	22	25,671,513 - 25,731,364 (+)	NCBI		Celera
Cytogenetic Map	22	q13.2	ENTREZGENE
HuRef	22	24,830,931 - 24,890,807 (+)	NCBI		HuRef
CHM1_1	22	41,825,012 - 41,884,897 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	41,947,611 - 42,007,811 (+)	NCBI		T2T-CHM13v2.0

Aco2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	81,756,664 - 81,799,338 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	81,756,510 - 81,799,334 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	81,872,463 - 81,915,137 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	81,872,309 - 81,915,133 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	81,702,893 - 81,745,567 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	81,699,718 - 81,742,392 (+)	NCBI		MGSCv36	mm8
Celera	15	83,991,539 - 84,036,379 (+)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI
cM Map	15	38.26	NCBI

Aco2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	115,265,816 - 115,308,931 (+)	NCBI		GRCr8
mRatBN7.2	7	113,385,677 - 113,428,794 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	113,385,646 - 113,428,261 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	115,148,102 - 115,191,078 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	117,371,597 - 117,414,574 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	117,341,038 - 117,384,016 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	123,102,493 - 123,145,608 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	123,102,468 - 123,145,635 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	123,077,888 - 123,121,003 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	120,223,788 - 120,266,944 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	120,258,017 - 120,301,166 (+)	NCBI
Celera	7	109,704,354 - 109,747,462 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

Aco2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	27,027,341 - 27,065,227 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	27,027,341 - 27,065,227 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACO2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	51,299,400 - 51,359,322 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	53,998,677 - 54,058,580 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	22,363,178 - 22,423,041 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	40,450,276 - 40,510,200 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	40,450,276 - 40,510,200 (+)	Ensembl	panpan1.1		panPan2

ACO2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	23,742,284 - 23,798,580 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	23,742,333 - 23,798,498 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	23,674,973 - 23,731,276 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	24,487,132 - 24,543,453 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	24,487,133 - 24,543,365 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	24,203,926 - 24,260,231 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	24,525,094 - 24,581,120 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	24,699,242 - 24,755,563 (-)	NCBI		UU_Cfam_GSD_1.0

Aco2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	7,397,068 - 7,442,218 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936492	407,482 - 452,537 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936492	407,482 - 452,538 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACO2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	24,008,602 - 24,068,346 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	24,008,667 - 24,071,356 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	101,348,982 - 101,410,178 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aco2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	7,074,153 - 7,113,773 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624752	7,074,148 - 7,113,773 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ACO2
1827 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	10	4	3	5	2	23	2	3	3
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_213954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK234325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK389334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK392093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU633382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBZA01000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01044892	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	J05224	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000000070 ⟹ ENSSSCP00000000070

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	7,014,289 - 7,071,025 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000097303 ⟹ ENSSSCP00000078340

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	7,008,719 - 7,071,023 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000105482 ⟹ ENSSSCP00000076303

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	7,008,719 - 7,071,023 (-)	Ensembl

RefSeq Acc Id:

NM_213954 ⟹ NP_999119

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	7,014,383 - 7,071,023 (-)	NCBI

Sequence:

show sequence

AAGCGACCTCATCTTTGTCAGTGCACAAAATGGCGCCTTACAGCCTACTGGTGACCCGGCTGCA
GAAAGCCCTGGGTGTGCGGCAGTACCATGTGGCCTCAGTCCTGTGCCAGCGGGCCAAGGTGGCC
ATGAGCCACTTCGAGCCCCACGAGTACATCCGCTATGACCTGCTTGAGAAGAACATCGACATCG
TTCGCAAGCGACTGAACCGGCCTCTGACCCTCTCAGAGAAGATTGTGTATGGACACCTGGATGA
CCCGGCCAACCAGGAGATCGAGCGGGGCAAGACGTACCTCCGTCTGCGGCCCGACCGCGTGGCC
ATGCAGGATGCCACGGCCCAGATGGCCATGCTGCAGTTCATCAGCAGTGGACTGCCCAAGGTGG
CCGTGCCCTCCACCATCCACTGTGACCATCTGATCGAGGCCCAGCTCGGGGGCGAGAAAGACCT
GCGTCGGGCCAAGGACATAAACCAGGAAGTGTATAACTTCCTGGCAACTGCAGGTGCCAAGTAC
GGCGTGGGCTTCTGGAGGCCTGGCTCCGGAATCATTCACCAGATCATTCTGGAAAACTACGCGT
ACCCTGGGGTTCTTCTGATCGGCACTGATTCCCACACCCCCAATGGCGGTGGCCTGGGGGGCAT
CTGCATTGGAGTCGGGGGTGCTGATGCCGTGGATGTCATGGCCGGGATCCCCTGGGAGCTGAAG
TGCCCCAAGGTGATTGGTGTGAAGCTGACGGGCTCGCTCTCTGGCTGGACCTCACCCAAAGATG
TGATCCTGAAGGTGGCGGGCATCCTCACCGTGAAAGGTGGCACGGGTGCCATCGTGGAGTACCA
TGGGCCTGGCGTGGACTCCATCTCCTGCACTGGCATGGCGACAATCTGCAACATGGGCGCAGAG
ATCGGGGCCACCACCTCCGTGTTTCCTTACAACCACAGGATGAAGAAGTACCTGAGCAAGACAG
GCCGGGCAGATATTGCCAACCTCGCTGACGAATTCAAGGACCACTTGGTACCTGACCCTGGCTG
CCATTATGACCAAGTGATTGAAATTAACCTCAGCGAGCTGAAGCCACACATCAACGGGCCCTTC
ACCCCTGACCTGGCTCACCCCGTGGCGGAAGTGGGCAGCGTGGCAGAGAAGGAGGGGTGGCCGC
TGGACATCCGAGTAGGTCTGATCGGCAGCTGTACCAACTCCAGCTATGAGGACATGGGGCGCTC
AGCAGCCGTGGCCAAGCAGGCACTGGCTCACGGACTCAAGTGCAAGTCCCAGTTTACCATCACA
CCGGGCTCTGAGCAGATCCGAGCCACCATTGAGCGGGATGGTTACGCACAGGTCCTGAGGGATG
TGGGCGGCATCGTCCTGGCCAATGCCTGCGGCCCCTGCATTGGCCAGTGGGACAGAAAGGACAT
CAAGAAGGGGGAGAAGAACACAATTGTCACCTCCTACAACCGCAACTTCACAGGCCGCAACGAC
GCCAACCCCGAGACCCATGCCTTCGTCACGTCCCCGGAGATTGTCACCGCCCTGGCCATCGCTG
GCACCCTCAAGTTCAACCCAGAGACTGACTTCCTGACAGGCAAGGATGGCAAGAAGTTCAAGCT
GGAGGCTCCGGACGCAGACGAGCTTCCCCGAGCGGAGTTCGACCCTGGACAGGACACGTACCAG
CACCCCCCCAAGGACAGCAGCGGGCAGCGGGTGGACGTGAGCCCCACCAGCCAGCGCCTGCAGC
TCCTGGAGCCTTTCGACAAGTGGGACGGCAAAGACCTGGAGGACCTGCAGATTCTCATCAAGGT
CAAAGGCAAGTGTACCACTGACCACATCTCGGCTGCTGGCCCCTGGCTCAAGTTCCGTGGGCAC
CTGGACAACATCTCCAATAACTTGCTCATCGGTGCCATCAACATTGAAAACCGCAAGGCCAACT
CCGTGCGCAATGCTGTCACCCAGGAGTTTGGTCCTGTCCCTGACACTGCCCGCTACTACAAGCA
ACACGGCATCCGGTGGGTGGTGATCGGAGATGAGAACTACGGCGAGGGCTCGAGCCGGGAGCAT
CGGGCCCTGGAGCCGCGCCACCTCGGGGGCCGGGCCATCATCACCAAGAGCTTCGCCAGGATCC
ACGAAACCAACCTGAAGAAGCAGGGCCTGCTGCCCCTGACCTTCGCCGACCCAGCGGACTACAA
CAAGATCCACCCCGTGGACAAGCTGACCATCCAGGGCCTGAAGGACTTTGCCCCTGGCAAGCCC
CTGAAGTGCATCATCAAGCACCCCAACGGGACCCAGGAGACCATCCTGCTGAACCACACTTTCA
ACGAGACCCAGATCGAGTGGTTCCGCGCCGGCAGTGCCCTCAACAGAATGAAGGAGCTGCAGCA
GAAATAAGGCCCTGCTCTGCCACCATGCCCACCGTCCGTCCTGCTCTTCAGGCCCAGCTCCGCT
GTCCCAAGTGCAGTCCATGTCATCAGAGCCGGACCTGAGCTGAGCCCGCCACGGCTTCACTCCG
AGAGGGTGCGGCCAGGCCCTCTCTTCCCTTGGCCCACGGAGTCCGGCCAGTTGGGGACAGGGGC
GAGGTTCGTAATGTTTCAACTCCTTGCCTTCCTGTTTTTAGTTTGATTCAGATCTTAAGCAGCT
TCATGCAACTGTATTTATTTTTGATGATAAGACTTCCATCT

hide sequence

Protein Sequences


Protein RefSeqs	NP_999119	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA30987	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000000070
	ENSSSCP00000000070.4
	ENSSSCP00000076303.1
	ENSSSCP00000078340.1
	ENSSSCP00005002569.1
	ENSSSCP00005002584.1
	ENSSSCP00070048417.1
	ENSSSCP00070048422.1
GenBank Protein	JAG69754	(Get FASTA)	NCBI Sequence Viewer
	P16276	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_999119 ⟸ NM_213954
- Peptide Label:	precursor
- UniProtKB:	P16276 (UniProtKB/Swiss-Prot), A0A8W4FBS4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPHEYIRYDLLEKNIDIVRKRLNRPLT LSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDH LIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTD SHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILT VKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLAD EFKDHLVPDPGCHYDQVIEINLSELKPHINGPFTPDLAHPVAEVGSVAEKEGWPLDIRVGLIGS CTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQVLRDVGGIVLANAC GPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETD FLTGKDGKKFKLEAPDADELPRAEFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDG KDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENRKANSVRNAVTQEF GPVPDTARYYKQHGIRWVVIGDENYGEGSSREHRALEPRHLGGRAIITKSFARIHETNLKKQGL LPLTFADPADYNKIHPVDKLTIQGLKDFAPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRA GSALNRMKELQQK hide sequence

RefSeq Acc Id:

ENSSSCP00000000070 ⟸ ENSSSCT00000000070

RefSeq Acc Id:

ENSSSCP00000078340 ⟸ ENSSSCT00000097303

RefSeq Acc Id:

ENSSSCP00000076303 ⟸ ENSSSCT00000105482

Protein Domains

Aconitase A/isopropylmalate dehydratase small Aconitase/3-isopropylmalate dehydratase large

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000000064	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005002824	UniProtKB/TrEMBL
	ENSSSCG00070028407	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000000070	ENTREZGENE
	ENSSSCT00000000070.5	UniProtKB/TrEMBL
	ENSSSCT00000097303.1	UniProtKB/TrEMBL
	ENSSSCT00000105482.1	UniProtKB/TrEMBL
	ENSSSCT00005004336.1	UniProtKB/TrEMBL
	ENSSSCT00005004370.1	UniProtKB/TrEMBL
	ENSSSCT00070056972.1	UniProtKB/TrEMBL
	ENSSSCT00070056978.1	UniProtKB/TrEMBL
Gene3D-CATH	3.20.19.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.499.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.1060.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Acnase/IPM_dHydase_lsu_aba_1/3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Acoase/IPM_deHydtase_lsu_aba	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Aconitase/3IPM_dehydase_swvl	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Aconitase_4Fe-4S_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Aconitase_4Fe-4S_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Aconitase_dom2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Aconitase_mito-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	AconitaseA/IPMdHydase_ssu_swvl	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	ssc:396999	UniProtKB/Swiss-Prot
NCBI Gene	ACO2	ENTREZGENE
PANTHER	ACONITATE HYDRATASE B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ACONITATE HYDRATASE, MITOCHONDRIAL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Aconitase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Aconitase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	ACONITASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ACONITASE_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ACONITASE_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	LeuD/IlvD-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF53732	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A4X1W359_PIG	UniProtKB/TrEMBL
	A0A4X1W364_PIG	UniProtKB/TrEMBL
	A0A8D0HYX0_PIG	UniProtKB/TrEMBL
	A0A8D0LDV2_PIG	UniProtKB/TrEMBL
	A0A8W4FBS4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8W4FGI3_PIG	UniProtKB/TrEMBL
	ACON_PIG	UniProtKB/Swiss-Prot
	F1SRC5_PIG	UniProtKB/TrEMBL
	P16276	ENTREZGENE
VGNC ID	VGNC:97865	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB