RARS1 (arginyl-tRNA synthetase 1) - Rat Genome Database
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Gene: RARS1 (arginyl-tRNA synthetase 1) Sus scrofa
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Symbol: RARS1
Name: arginyl-tRNA synthetase 1
RGD ID: 14126074
Description: ENCODES a protein that exhibits arginine binding (ortholog); arginine-tRNA ligase activity (ortholog); ATP binding (ortholog); INVOLVED IN arginyl-tRNA aminoacylation (ortholog); ASSOCIATED WITH hypomyelinating leukodystrophy 9 (ortholog); FOUND IN aminoacyl-tRNA synthetase multienzyme complex (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: arginine--tRNA ligase, cytoplasmic; arginyl-tRNA synthetase; ARGRS; RARS
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1655,373,726 - 55,412,117 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11655,373,739 - 55,412,076 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21659,959,187 - 59,972,120 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
RARS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1655,373,726 - 55,412,117 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11655,373,739 - 55,412,076 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21659,959,187 - 59,972,120 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RARS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5168,486,451 - 168,519,301 (+)EnsemblGRCh38hg38GRCh38
GRCh385168,486,471 - 168,519,301 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375167,913,476 - 167,946,306 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh375167,913,463 - 167,946,311 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365167,846,041 - 167,878,889 (+)NCBINCBI36hg18NCBI36
Build 345167,846,040 - 167,878,885NCBI
Celera5163,948,808 - 163,981,683 (+)NCBI
Cytogenetic Map5q34NCBI
HuRef5163,012,238 - 163,045,058 (+)NCBIHuRef
CHM1_15167,346,530 - 167,379,378 (+)NCBICHM1_1
Rars
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,699,207 - 35,725,355 (-)NCBIGRCm39mm39
GRCm381135,808,381 - 35,834,528 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,808,381 - 35,834,506 (-)EnsemblGRCm38mm10GRCm38
MGSCv371135,621,883 - 35,648,030 (-)NCBIGRCm37mm9NCBIm37
MGSCv361135,651,806 - 35,677,929 (-)NCBImm8
Celera1139,591,462 - 39,617,635 (-)NCBICelera
Cytogenetic Map11A4NCBI
Rars1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21020,270,744 - 20,295,192 (-)NCBI
Rnor_6.0 Ensembl1020,633,632 - 20,658,100 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01020,633,630 - 20,658,074 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01020,505,807 - 20,530,334 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41020,721,170 - 20,745,484 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11020,722,223 - 20,746,536 (-)NCBI
Celera1019,889,464 - 19,913,910 (-)NCBICelera
Cytogenetic Map10q12NCBI
Rars1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540821,536,426 - 21,574,683 (+)NCBIChiLan1.0ChiLan1.0
RARS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15170,616,819 - 170,649,655 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5170,616,819 - 170,649,655 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05163,851,644 - 163,884,787 (+)NCBIMhudiblu_PPA_v0panPan3
RARS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl443,237,499 - 43,260,677 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1443,237,499 - 43,260,738 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rars1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936622884,324 - 917,964 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RARS1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12370,711,435 - 70,746,000 (+)NCBI
ChlSab1.1 Ensembl2370,711,016 - 70,745,884 (+)Ensembl
Rars1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473321,487,847 - 21,535,487 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 2 3 5 2 17 1 3 3
Low 2 6 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000018527   ⟹   ENSSSCP00000018027
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1655,373,726 - 55,412,117 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000068343   ⟹   ENSSSCP00000072735
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1655,373,726 - 55,411,473 (-)Ensembl
RefSeq Acc Id: NM_001244260   ⟹   NP_001231189
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11655,373,739 - 55,412,076 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001231189 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAS55913 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001231189   ⟸   NM_001244260
- UniProtKB: F1RR89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000072735   ⟸   ENSSSCT00000068343
RefSeq Acc Id: ENSSSCP00000018027   ⟸   ENSSSCT00000018527
Protein Domains
Arg_tRNA_synt_N   DALR_1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017015 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000018027 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000072735 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018527 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000068343 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1360.70 UniProtKB/TrEMBL
  3.40.50.620 UniProtKB/TrEMBL
InterPro aa-tRNA-synth_I_CS UniProtKB/TrEMBL
  Arg-tRNA-ligase UniProtKB/TrEMBL
  Arg-tRNA-synth_N UniProtKB/TrEMBL
  Arg-tRNA-synth_N_sf UniProtKB/TrEMBL
  ArgRS_core UniProtKB/TrEMBL
  DALR_anticod-bd UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
  tRNAsynth_Ia_anticodon-bd UniProtKB/TrEMBL
KEGG Report ssc:414410 UniProtKB/TrEMBL
NCBI Gene RARS ENTREZGENE
PANTHER PTHR11956 UniProtKB/TrEMBL
Pfam Arg_tRNA_synt_N UniProtKB/TrEMBL
  DALR_1 UniProtKB/TrEMBL
  tRNA-synt_1d UniProtKB/TrEMBL
PRINTS TRNASYNTHARG UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_I UniProtKB/TrEMBL
SMART Arg_tRNA_synt_N UniProtKB/TrEMBL
  DALR_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF47323 UniProtKB/TrEMBL
  SSF55190 UniProtKB/TrEMBL
TIGRFAMs argS UniProtKB/TrEMBL
UniProt A0A5G2RDY5_PIG UniProtKB/TrEMBL
  F1RR89 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92099 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-23 RARS1  arginyl-tRNA synthetase 1  RARS  arginyl-tRNA synthetase  Symbol and/or name change 5135510 APPROVED