TMED8 (transmembrane p24 trafficking protein family member 8) - Rat Genome Database

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Gene: TMED8 (transmembrane p24 trafficking protein family member 8) Sus scrofa
Analyze
Symbol: TMED8
Name: transmembrane p24 trafficking protein family member 8
RGD ID: 14123708
Description: ASSOCIATED WITH genetic disease (ortholog); hereditary sensory and autonomic neuropathy type 1C (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein TMED8; transmembrane emp24 protein transport domain containing 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7100,411,264 - 100,449,298 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17100,411,259 - 100,449,350 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27106,507,882 - 106,540,567 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
TMED8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7100,411,264 - 100,449,298 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17100,411,259 - 100,449,350 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27106,507,882 - 106,540,567 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMED8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381477,335,021 - 77,377,094 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1477,335,029 - 77,377,094 (-)EnsemblGRCh38hg38GRCh38
GRCh371477,801,364 - 77,843,437 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361476,877,867 - 76,913,149 (-)NCBINCBI36Build 36hg18NCBI36
Build 341476,877,866 - 76,913,149NCBI
Celera1457,846,691 - 57,881,972 (-)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1457,974,194 - 58,009,463 (-)NCBIHuRef
CHM1_11477,747,564 - 77,782,831 (-)NCBICHM1_1
T2T-CHM13v2.01471,544,384 - 71,586,469 (-)NCBIT2T-CHM13v2.0
Tmed8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391287,195,547 - 87,247,264 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1287,213,011 - 87,247,228 (-)EnsemblGRCm39 Ensembl
GRCm381287,166,242 - 87,200,457 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1287,166,237 - 87,200,454 (-)EnsemblGRCm38mm10GRCm38
MGSCv371288,507,192 - 88,541,179 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361288,055,345 - 88,089,332 (-)NCBIMGSCv36mm8
Celera1288,630,768 - 88,664,814 (-)NCBICelera
Cytogenetic Map12D2NCBI
cM Map1241.36NCBI
Tmed8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86112,537,921 - 112,572,199 (-)NCBIGRCr8
mRatBN7.26106,806,973 - 106,841,271 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6106,810,420 - 106,843,216 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.06111,188,938 - 111,222,866 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,194,951 - 111,222,858 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06120,473,103 - 120,506,844 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera6104,628,254 - 104,662,575 (-)NCBICelera
Cytogenetic Map6q31NCBI
Tmed8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554381,246,301 - 1,272,815 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554381,246,301 - 1,273,113 (-)NCBIChiLan1.0ChiLan1.0
TMED8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21578,418,890 - 78,461,242 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11477,635,394 - 77,677,746 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01457,888,235 - 57,930,615 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11477,089,637 - 77,132,037 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1477,096,398 - 77,132,037 (-)Ensemblpanpan1.1panPan2
TMED8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1850,149,099 - 50,163,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl850,156,060 - 50,164,339 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha849,836,775 - 49,869,837 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0850,382,641 - 50,415,947 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl850,387,795 - 50,415,938 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1850,045,477 - 50,078,545 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0850,068,840 - 50,101,841 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0850,466,520 - 50,499,588 (-)NCBIUU_Cfam_GSD_1.0
Tmed8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864025,892,367 - 25,911,257 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364886,165,874 - 6,176,595 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364886,159,119 - 6,176,584 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMED8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12454,595,024 - 54,636,235 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605342,781,717 - 42,828,610 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmed8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473424,526,414 - 24,562,599 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473424,526,410 - 24,569,901 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMED8
1079 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 3 1 6 2 1
Low 9 4 4 2 17 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000057805   ⟹   ENSSSCP00000054249
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl7100,411,264 - 100,449,298 (-)Ensembl
RefSeq Acc Id: XM_003356761   ⟹   XP_003356809
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.17100,411,259 - 100,449,350 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013989199   ⟹   XP_013844653
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.17100,411,259 - 100,429,749 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021099552   ⟹   XP_020955211
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.17100,419,493 - 100,449,350 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003356809   ⟸   XM_003356761
- Peptide Label: isoform X1
- UniProtKB: A0A287BD45 (UniProtKB/TrEMBL),   A0A4X1T2Z3 (UniProtKB/TrEMBL),   A0A8D0HUL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013844653   ⟸   XM_013989199
- Peptide Label: isoform X2
- UniProtKB: A0A8D0HUM1 (UniProtKB/TrEMBL),   A0A8D0HUL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020955211   ⟸   XM_021099552
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSSSCP00000054249   ⟸   ENSSSCT00000057805
Protein Domains
GOLD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000036028 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005002280 UniProtKB/TrEMBL
  ENSSSCG00015037403 UniProtKB/TrEMBL
  ENSSSCG00025067516 UniProtKB/TrEMBL
  ENSSSCG00030031075 UniProtKB/TrEMBL
  ENSSSCG00035026239 UniProtKB/TrEMBL
  ENSSSCG00040026948 UniProtKB/TrEMBL
  ENSSSCG00045033862 UniProtKB/TrEMBL
  ENSSSCG00050051170 UniProtKB/TrEMBL
  ENSSSCG00055003151 UniProtKB/TrEMBL
  ENSSSCG00060001438 UniProtKB/TrEMBL
  ENSSSCG00065065623 UniProtKB/TrEMBL
  ENSSSCG00070006448 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000057805 ENTREZGENE
  ENSSSCT00000057805.2 UniProtKB/TrEMBL
  ENSSSCT00005003436.1 UniProtKB/TrEMBL
  ENSSSCT00005003454.1 UniProtKB/TrEMBL
  ENSSSCT00015049739.1 UniProtKB/TrEMBL
  ENSSSCT00025092725.1 UniProtKB/TrEMBL
  ENSSSCT00030043106.1 UniProtKB/TrEMBL
  ENSSSCT00035034595.1 UniProtKB/TrEMBL
  ENSSSCT00040036054.1 UniProtKB/TrEMBL
  ENSSSCT00045057878.1 UniProtKB/TrEMBL
  ENSSSCT00050069683.1 UniProtKB/TrEMBL
  ENSSSCT00055006093.1 UniProtKB/TrEMBL
  ENSSSCT00060001746.1 UniProtKB/TrEMBL
  ENSSSCT00065090069.1 UniProtKB/TrEMBL
  ENSSSCT00070012313.1 UniProtKB/TrEMBL
Gene3D-CATH GOLD domain UniProtKB/TrEMBL
InterPro GOLD_dom UniProtKB/TrEMBL
  GOLD_dom_sf UniProtKB/TrEMBL
NCBI Gene TMED8 ENTREZGENE
PANTHER LD35087P UniProtKB/TrEMBL
  PROTEIN TMED8 UniProtKB/TrEMBL
Pfam GOLD_2 UniProtKB/TrEMBL
PROSITE GOLD UniProtKB/TrEMBL
Superfamily-SCOP SSF101576 UniProtKB/TrEMBL
UniProt A0A287BD45 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1T2Z3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0HUL0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0HUM1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:94058 ENTREZGENE